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Preparation of Nano-emulsion Containing Polygonum aviculare Extract for Enhanced Transdermal Delivery (피부 흡수 증진을 위한 마디풀 추출물 함유 나노에멀젼 제조에 관한 연구)

  • Lim, Myoung Sun;Park, Min A;Park, Soo Nam
    • Applied Chemistry for Engineering
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    • v.23 no.2
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    • pp.222-227
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    • 2012
  • In this study, nano-emulsion containing ethyl acetate fraction of Polygonum aviculare (P. aviculare) extract was prepared and skin permeability of the nano-emulsion was evaluated. Nano-emulsion was prepared using homogenizer and microfluidizer by the high-energy method. The droplet size and loading efficiency of nano-emulsion containing ethyl acetate fraction of P. aviculare extract were determined. The mean droplet size was 238 nm and the loading efficiency was more than 98%. The size distribution of nano-emulsion was a monodispersed form and nano-emulsion was more stable than that of using typical emulsion without using the microfluidizer. The in vitro skin permeation study of nano-emulsion containing ethyl acetate fraction of P. aviculare extract was carried out using Franz diffusion cells. Compared to 1,3-butylene glycol, nano-emulsion showed greater values of cumulative permeation of ethyl acetate fraction from P. aviculare extract. These results indicate that the stability and skin permeability of nano-emulsion containing ethyl acetate fraction of P. aviculare exerting anti-oxidative and anti-aging activities were enhanced.

Effect of SPR Chip with Nano-structured Surface on Sensitivity in SPR Sensor (나노형상을 가진 표면플라즈몬공명 센서칩의 감도 개선 효과)

  • Cho, Yong-Jin;Kim, Chul-Jin;Kim, Namsoo;Kim, Chong-Tai;Kim, Tae-Eun;Kim, Hyo-Sop;Kim, Jae-Ho
    • Food Engineering Progress
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    • v.14 no.1
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    • pp.49-53
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    • 2010
  • Surface plasmon resonance (SPR) which is utilized in thin film refractometry-based sensors has been concerned on measurement of physical, chemical and biological quantities because of its high sensitivity and label-free feature. In this paper, an application of SPR to detection of alcohol content in wine and liquor was investigated. The result showed that SPR sensor had high potential to evaluate alcohol content. Nevertheless, food industry may need SPR sensor with higher sensitivity. Herein, we introduced a nano-technique into fabrication of SPR chip to enhance SPR sensitivity. Using Langmuir-Blodgett (LB) method, gold film with nano-structured surface was devised. In order to make a new SPR chip, firstly, a single layer of nano-scaled silica particles adhered to plain surface of gold film. Thereafter, gold was deposited on the template by an e-beam evaporator. Finally, the nano-structured surface with basin-like shape was obtained after removing the silica particles by sonication. In this study, two types of silica particles, or 130 nm and 300 nm, were used as template beads and sensitivity of the new SPR chip was tested with ethanol solution, respectively. Applying the new developed SPR sensor to a model food of alcoholic beverage, the sensitivity showed improvement of 95% over the conventional one.

Characteristics of Remote Sensors on KOMPSAT-I (다목적 실용위성 1호 탑재 센서의 특성)

  • 조영민;백홍렬
    • Korean Journal of Remote Sensing
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    • v.12 no.1
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    • pp.1-16
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    • 1996
  • Korea Aerospace Research Institute(KARI) is developing a Korea Multi-Purpose Satellite I(KOMPSAT-I) which accommodates Electro-Optical Camera(EOC), Ocean Color Imager(OCI), Space Physics Sensor(SPS) for cartography, ocean color monitoring, and space environment monitoring respectively. The satellite has the weight of about 500 kg and is operated on the sun synchronized orbit with the altitude of 685km, the orbit period of 98 minutes, and the orbit revisit time of 28days. The satellite will be launched in the third quarter of 1999 and its lifetime is more than 3 years. EOC has cartography mission to provide images for the production of scale maps, including digital elevation models, of Korea from a remote earth view in the KOMPSAT orbit. EOC collects panchromatic imagery with the ground sample distance(GSD) of 6.6m and the swath width of 15km at nadir through the visible spectral band of 510-730 nm. EOC scans the ground track of 800km per orbit by push-broom and body pointed method. OCI mission is worldwide ocean color monitoring for the study of biological oceanography. OCI is a multispectral imager generating 6 color ocean images with and <1km GSD by whisk-broom scanning method. OCI is designed to provide on-orbit spectral band selectability in the spectral range from 400nm to 900nm. The color images are collected through 6 primary spectral bands centered at 443, 490, 510, 555, 670, 865nm or 6 spectral bands selected in the spectral range via ground commands after launch. SPS consists of High Energy Particle Detector(HEPD) and Ionosphere Measurement Sensor(IMS). HEPD has mission to characterize the low altitude high energy particle environment and to study the effects of radiation environment on microelectronics. IMS measures densities and temperature of electrons in the ionosphere and monitors the ionospheric irregularities in KOMPSAT orbit.

Characteristics of particulate matter collection efficiency and ozone emission rate of an electrostatic precipitator by thickness of high-voltage electrode and distance of collection plates (고전압 전극 두께와 집진판 간격에 따른 전기집진기의 미세먼지 집진효율 및 오존발생 특성)

  • Lee, Jae-In;Woo, Sang-Hee;Kim, Jong Bum;Lee, Seung-Bok;Bae, Gwi-Nam
    • Particle and aerosol research
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    • v.14 no.4
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    • pp.171-180
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    • 2018
  • To optimize the shape of the electrostatic precipitator for the removal of particulate matter in subway environments, the wind-tunnel experiments were carried out to characterize collection efficiency and ozone emission rate. As a standardized parameter, power consumption divided by the square of flow velocity, was increased, the $PM_{10}$ collection efficiency increased. If the standardized parameter is higher than 1.0 due to high power consumption or low flow velocity, increase in thickness of electrodes from 1 to 2 mm, or increase in distance of collection plates from 5 to 10 cm did not change the $PM_{10}$ collection efficiency much. Increase in thickness of high-voltage electrodes, however, can cause decrease in $PM_{10}$ collection efficiency by 28% for low power consumption and high flow velocity. The ozone emission rate decreased as distance of collection plates became wider, because the ozone emission rate per unit channel was constant, and the number of collection channels decreased as the distance of collection plates increased. When the distance of collection plates was narrow, the ozone emission rate increased with the increase of the thickness of electrodes, but the difference was negligible when the distance of collection plates was wide. It was found that the electrostatic precipitator having a thin high-voltage electrodes and a narrow distance of collection plates is advantageous. However, to increase the thickness of high-voltage electrodes, or to increase the distance of collection plates is needed, it is necessary to increase the applied voltage or reduce the flow rate to compensate reduction of the collection efficiency.

Isotherm, Kinetic, Thermodynamic and Competitive for Adsorption of Brilliant Green and Quinoline Yellow Dyes by Activated Carbon (활성탄에 의한 Brilliant Green과 Quinoline Yellow 염료의 흡착에 대한 등온선, 동력학, 열역학 및 경쟁흡착)

  • Lee, Jong Jib
    • Korean Chemical Engineering Research
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    • v.59 no.4
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    • pp.565-573
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    • 2021
  • Isotherms, kinetics and thermodynamic properties for adsorption of Brilliant Green(BG), Quinoline Yellow(QY) dyes by activated carbon were carried out using variables such as dose of adsorbent, pH, initial concentration, contact time, temperature and competitive. BG showed the highest adsorption rate of 92.4% at pH 11, and QY was adsorbed at 90.9% at pH 3. BG was in good agreement with the Freundlich isothermal model, and QY was well matched with Langmuir model. The separation coefficients of isotherm model indicated that these dyes could be effectively treated by activated carbon. Estimated adsorption energy by Temkin isotherm model indicated that the adsorption of BG and QY by activated carbon is a physical adsorption. The kinetic experimental results showed that the pseudo second order model had a better fit than the pseudo first order model with a smaller in the equilibrium adsorption amount. It was confirmed that surface diffusion was a rate controlling step by the intraparticle diffusion model. The activation energy and enthalpy change of the adsorption process indicated that the adsorption process was a relatively easy endothermic reaction. The entropy change indicated that the disorder of the adsorption system increased as the adsorption of BG and QY dyes to activated carbon proceeded. Gibbs free energy was found that the adsorption reaction became more spontaneous with increasing temperature. As a result of competitive adsorption of the mixed solution, it was found that QY was disturbed by BG and the adsorption reduced.

Evaluation of NOx Reduction Performance by Photocatalytic (TiO2) Coating of Cement Mortar Mixed with Zeolite and Activate Hwangtoh (제올라이트와 활성 황토를 혼입한 시멘트 모르타르의 광촉매(TiO2) 코팅에 따른 NOx 저감성능평가)

  • Park, Jang-Hyun;Kim, Hyeok-Jung
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.8 no.4
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    • pp.483-489
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    • 2020
  • Particulate matter is divided into PM10 (particle diameter of 10 ㎛ or less) and PM2.5 (particle diameter of 2.5 ㎛ or less), which are approximately 1/5 of the thickness of the hair. Due to its effect on the human body, lung disease, arteriosclerosis and heart It is known as a carcinogen that causes various diseases such as diseases. It is known that the main cause of such fine dust is nitrogen dioxide (NOx), which is emitted from automobiles in about 57.3% of urban roadsides. Therefore, in this study, as part of the development of functional construction materials to reduce NOx generated from road transport pollutants, comparative evaluation of NOx reduction performance was conducted according to the replacement rate of cement mortar in which cement was replaced with a porous material. In addition, the NOx reduction performance of cement mortar according to the photocatalyst application method and the number of applications was compared an d evaluated. As a result of the experiment, when activated ocher was substituted by 30%, it showed a reduction effect of about 32.7%, showing the best reduction performance.

The study on collection efficiency of two-stage electrostatic precipitator using non-metallic electrode for improve corrosion resistance and light weight (내부식성과 경량성 향상을 위한 비금속 재질 집진판의 2단 전기집진기 집진효율 연구)

  • An, So-Hee;Lee, Yeawan;Kim, Ye-Sle;Kim, Yong-Jin;Han, Bangwoo;Kim, Hak-Joon
    • Particle and aerosol research
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    • v.17 no.2
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    • pp.21-27
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    • 2021
  • We developed non-metallic electrodes that can replace metallic electrodes of the electrostatic precipitator(ESP) for the purpose of light weight, corrosion resistance, cost reduction. We manufactured three types of collection electrodes made of stainless steel (M), Carbon ink coating layer-Plastic sheet-Carbon ink coating layer (CPC), and Plastic sheet-Carbon ink coating layer-Plastic sheet (PCP). We studied the collection efficiency of a two-stage ESP using oil mist particles with and without collection stage by changing the flow rate, the material of collection electrode, and the applied voltage of the pre-charger module and the collection module. Here we measured concentrations of particles at diameters of 0.45 ㎛ (CMD; count median diameter) and 3.0 ㎛ (MMD : mass median diameter), as well as PM2.5 and PM10. As a result of the experiment, two-stage ESP had 22~25% higher collection efficiency in PM2.5 than one-stage ESP at the same applied voltage. The difference in collection efficiency by varying the materials of collection electrodes was less than 5%. The weight of the non-metallic electrode was only one eighth the weight of the metal electrode. CPC electrode had a thickness of 0.27 mm, which was 1.5 times thinner than a thickness of PCP electrode, so when the flow rate increased, the CPC electrodes couldn't be kept at equal intervals due to the fluttering unlike PCP electrodes. In addition, the PCP-CPC collection module of the present experiment followed the theoretical efficiency based on Deutsch equation and Cochet's charging theory.

A Study on collection efficiency of two-stage electrostatic precipitator using PET-coated non-metallic electrode with respect to relative humidity (PET 코팅된 비금속 집진판을 사용한 2단 전기집진기의 상대습도에 따른 집진효율 연구)

  • Haneol Lee;Gwangtaek Lee;So-Hee An;Ye Won Park;Gunhee Lee;Kee Jung Hong;Inyong Park;Sang Bok Kim;Daehoon Park;Yeawan Lee;Dong-Keun Song;Yong-Jin Kim;Bangwoo Han;Hak-Joon Kim
    • Particle and aerosol research
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    • v.19 no.3
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    • pp.53-62
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    • 2023
  • This study compared the collection efficiency of a two-stage electrostatic precipitator (ESP) with a lightweight PET film-coated carbon electrode collector plate, depending on the relative humidity of the exhaust gas and the applied voltage to the pre-charger. It was confirmed that the onset voltage at which corona discharge occurs decreases and the discharge current decreases at the same voltage as the relative humidity increases. On the other hand, even though there was almost no change in the diameter of the particles generated depending on the relative humidity, the efficiency was higher at the same voltage as the relative humidity increased. In addition, by applying a two-stage ESP structure, the collection efficiency was higher than that of a single-stage electrostatic precipitator under the same conditions. The ESP using the carbon electrode coated with PET film used in this study is expected to be effective in various aspects such as weight and in the current situation where environmental regulations are rapidly tightening.

Improving Thermal Conductivity of Neutron Absorbing B4C/Al Composites by Introducing cBN Reinforcement (cBN 입자상 강화재 첨가에 따른 중성자 흡수용 B4C/Al 복합재의 열전도도 변화 연구)

  • Minwoo Kang;Donghyun Lee;Tae Gyu Lee;Junghwan Kim;Sang-Bok Lee;Hansang Kwon;Seungchan Cho
    • Composites Research
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    • v.36 no.6
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    • pp.435-440
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    • 2023
  • This study aimed to enhance the thermal conductivity of B4C/Al composite materials, commonly used in transport/storage containers for spent nuclear fuel, by incorporating both boron carbide (B4C) and cubic boron nitride(cBN) as reinforcing agents in an aluminum (Al) matrix. The composite materials were successfully manufactured through a stir casting process and practical neutron-absorbing materials were obtained by rolling the fabricated composite ingot. The evaluation of the thermal conductivity of the fabricated composites was carried out because thermal conductivity is critical for neutron absorbing materials. The thermal conductivity measurement results indicated an approximately 3% increase in thermal conductivity under the same volume fraction when compared to composite materials using only B4C particles. Through neutron absorption cross-sectional area calculations, it was confirmed that the neutron absorption capability decreased to a negligible level. Based on the findings of this study, new design approaches for neutron absorption materials are proposed, contributing to the development of high-performance transport/storage containers.

Green Synthesis of Nanoceria and the Mechanism Behind Their Antibacterial Activity (나노세리아의 친환경 합성과 항균 활성 메커니즘)

  • Maheshkumar Prakash Patil;Yong-Suk Lee;Mi Jeong Jo;Yong Bae Seo;Gun-Do Kim
    • Journal of Life Science
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    • v.34 no.9
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    • pp.647-655
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    • 2024
  • The synthesis of cerium oxide nanoparticles (nanoceria, CeO2) has received significant attention across scientific and technological disciplines in the last decade. This article explores an overview of the green synthesis method and the antibacterial activity of nanoceria. The utilization of biological materials, such as plants and microorganisms, in the synthesis of nanoceria, has gained attention as an ecofriendly approach. Plants are rich in phytochemicals, including alkaloids, flavonoids, phenols, proteins, and other nutritious components. Likewise, microorganisms generate bioactive metabolites, pigments, enzymes, proteins, acids, and antibiotics. The phytochemicals and metabolites are involved in the reduction of metal salt into nanoceria and provide stability to synthesized nanoparticles. Nanoceria synthesis using plants and microorganisms is facile and ecofriendly, and synthesized nanoceria are biocompatible. Many biomedical applications of nanoceria have been reported, including those that are anticancer, anti-inflammatory, larvicidal, enzyme inhibiting, antibiofilm, and antimicrobial. However, in this review, we focused on and described in detail the antibacterial potential of nanoceria. The antibacterial activity of nanoceria occurs due to excessive reactive oxygen species generation, the impairment of the cell membrane, and the inhibition of cellular mechanisms. Ultimately, this review's primary goal is to provide readers with a logical understanding of the significant achievements of nanoceria as a cutting-edge therapeutic agent for treating a range of microbial pathogens and combating other diseases.