• The Korean Journal of Nuclear Medicine Technology
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• v.20 no.1
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• pp.32-36
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• 2016

Purpose In nuclear medicine examination, $^{131}I$ is widely used in nuclear medicine examination such as diagnosis, treatment, and others of thyroid cancer and other diseases. $^{131}I$ conducts examination and treatment through emission of ${\gamma}$ ray and ${\beta}^-$ ray. Since $^{131}I$ (364 keV) contains more energy compared to $^{99m}Tc$ (140 keV) although it displays high integrated rate and enables quick discharge through kidney, the objective of this study lies in comparing the difference in exposure dose of $^{131}I$ before and after wearing apron when handling $^{131}I$ with focus on 3 elements of external exposure protection that are distance, time, and shield in order to reduce the exposure to technicians in comparison with $^{99m}Tc$ during the handling and administration process. When wearing apron (in general, Pb 0.5 mm), $^{99m}Tc$ presents shield of over 90% but shielding effect of $^{131}I$ is relatively low as it is of high energy and there may be even more exposure due to influence of scattered ray (secondary) and bremsstrahlung in case of high dose. However, there is no special report or guideline for low dose (74 MBq) high energy thus quantitative analysis on exposure dose of technicians will be conducted based on apron wearing during the handling of $^{131}I$. Materials and Methods With patients who visited Department of Nuclear Medicine of our hospital for low dose $^{131}I$ administration for thyroid cancer and diagnosis for 7 months from Jun 2014 to Dec 2014 as its subject, total 6 pieces of TLD was attached to interior and exterior of apron placed on thyroid, chest, and testicle from preparation to administration. Then, radiation exposure dose from $^{131}I$ examination to administration was measured. Total procedure time was set as within 5 min per person including 3 min of explanation, 1 min of distribution, and 1 min of administration. In regards to TLD location selection, chest at which exposure dose is generally measured and thyroid and testicle with high sensitivity were selected. For preparation, 74 MBq of $^{131}I$ shall be distributed with the use of $2m{\ell}$ syringe and then it shall be distributed after making it into dose of $2m{\ell}$ though dilution with normal saline. When distributing $^{131}I$ and administering it to the patient, $100m{\ell}$ of water shall be put into a cup, distributed $^{131}I$ shall be diluted, and then oral administration to patients shall be conducted with the distance of 1m from the patient. The process of withdrawing $2m{\ell}$ syringe and cup used for oral administration was conducted while wearing apron and TLD. Apron and TLD were stored at storage room without influence of radiation exposure and the exposure dose was measured with request to Seoul Radiology Services. Results With the result of monthly accumulated exposure dose of TLD worn inside and outside of apron placed on thyroid, chest, and testicle during low dose $^{131}I$ examination during the research period divided by number of people, statistics processing was conducted with Wilcoxon Signed Rank Test using SPSS Version. 12.0K. As a result, it was revealed that there was no significant difference since all of thyroid (p = 0.345), chest (p = 0.686), and testicle (p = 0.715) were presented to be p > 0.05. Also, when converting the change in total exposure dose during research period into percentage, it was revealed to be -23.5%, -8.3%, and 19.0% for thyroid, chest, and testicle respectively. Conclusion As a result of conducting Wilcoxon Signed Rank Test, it was revealed that there is no statistically significant difference (p > 0.05). Also, in case of calculating shielding rate with accumulate exposure dose during 7 months, it was revealed that there is irregular change in exposure dose for inside and outside of apron. Although the degree of change seems to be high when it is expressed in percentage, it cannot be considered a big change since the unit of accumulated exposure dose is in decimal points. Therefore, regardless of wearing apron during high energy low dose $^{131}I$ administration, placing certain distance and terminating the administration as soon as possible would be of great assistance in reducing the exposure dose. Although this study restricted $^{131}I$ administration time to be within 5 min per person and distance for oral administration to be 1m, there was a shortcoming to acquire accurate result as there was insufficient number of N for statistics and it could be processed only through non-parametric method. Also, exposure dose per person during lose dose $^{131}I$ administration was measured with accumulated exposure dose using TLD rather than through direct-reading exposure dose thus more accurate result could be acquired when measurement is conducted using electronic dosimeter and pocket dosimeter.

• The Journal of the Korean bone and joint tumor society
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• v.8 no.1
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• pp.1-11
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• 2002

Purpose : We evaluated the radiological and functional results of prosthetic reconstruction for locally aggressive benign and malignant tumor in the lower extremity. Materials and Methods : Eighty eight patients were followed up for an average 76 months(22~174). We examined the survival rate of prosthesis, and evaluated the final result by MSTS functional score and ISOLS radiological implants evaluation system. They were statistically analyzed according to the age(<20 year vs. ${\geq}$20 year), fixation methods, amount of bony resection, chemotherapy, local recurrence, and presence of metastasis. Results : The 5 year prosthetic survival rates were 100% in the proximal femur, 83.3% in the distal femur, 81.9% in the proximal tibia. Mean total functional scores were 73.3%, 72%, 68.7%, respectively. In distal femur, the non-chemotherapeutic group was superior in the prosthetic survival rate. Recurrence or metastasis affected the functions in the distal femur and proximal tibia. In the radiological evaluation of the distal femur, older patients over 20 years of age and with cement fixation were superior in bone remodeling(p<0.05). Postoperative infection and radiological loosening were the main causes of the prosthetic failure. Conclusion : The prosthetic reconstruction in the lower extremity led to good clinical and radiological results. Amount of bony resection, chemotherapy, recurrence and metastasis seemed to influence the prosthetic survival, and long-term follow-up will be necessary to investigate more significant prognostic factors.

• Journal of Yeungnam Medical Science
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• v.22 no.1
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• pp.72-80
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• 2005

Background: Nasopharyngeal cancer is a rare disease with a relatively poor prognosis because it tends to be diagnosed at an advanced stage. The aim of this study was to establish the clinical characteristics of nasopharyngeal cancer. Materials and Methods: The medical records of 54 patients with nasopharyngeal cancer from January 1993 to December 2002 were reviewed retrospectively. Forty one cases were male (75.9%) and thirteen were female (24.1%). The average age was of 46.9 (range 16 to 78 years) years. The majority of patients (79.6%) were diagnosed in the advanced stage. The most common complaints were a neck mass (55.5%) and the WHO type III (53.7%) was the most frequent histological type. Results: The cumulative survival rate for a 5-year period was 46.5% and the T stage, N stage, pathologic type, and clinical stage were not significantly related to the survival rate. Sixteen of 54 (31.5%) cases presented with a distant metastasis of the bone, lung, brain, spine, and liver, and six cases (11.1%) presented with a locoregional recurrence. Conclusion: TNM staging is not appropriate for predicting survival rate of nasopharyngeal carcinoma patients. Therefore, a newer staging system, which includes new factors, is needed to predict the prognosis.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.46 no.3
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• pp.189-194
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• 2001

It is possible to use hairy vetch as green manure for corn not only in corn single cropping but also in double cropping system of corn and fall oats. Fall oats and hairy vetch were mixed-sown after corn harvest and harvested as forage in the early of November, and then hairy vetch stubble was over-wintered and incorporated into soil at corn planting as green manure without N fertilizer (FO+HV-GM). Other treatments were fall oats without N fertilizer on corn (FO-0N) and with N fertilizer 200kg/ha on corn (FO-200N), hairy vetch green manure without N fertilizer on corn (HV-GM), and fell winter follow without N fertilizer on corn (WF-0N). Soil nitrate content, corn growth and nitrogen uptakes, and yield of corn were measured and compared during 2-year experimental seasons. Dry matter and N amount of hairy vetch at the plot of FO+HV-GM were 60% less than those at the plot of HV-GM. The N effect of hairy vetch green manure on corn at the plot of HV-GM was similar to that at FO-200N plot for two years. Soil nitrate at the plot of FO+HV-GM was below the half of those at plots of HV-GM and FO-200N at 6-leaf stage of corn. N uptake of corn at the plot of FO+HV-GM at silking stage was 30% less than those at plot of HV-GM and FO-200N. However, soil nitrate at 6-leaf stage of corn and the amount of nitrogen uptake of corn at silking stage increased two times and 30-40 kg/ha, respectively, compared with those at the plot of FO-0N. Corn yield at FO+HV-GM decreased about 2 ton/ha due to the decrease of corn grain weight in the first year compared with plot of HV-GM and FO-200N, but its difference was not shown in succeeding second year. Corn N uptake at FO+HV-GM decreased 60 kg/ha and 20 kg/ha in 1999 and 2000, compared with plot of HV-GM and FO-200N, respectively, but increased 30kg/ha and 45kg/ha compared with the plot of FO-0N in 1999, 2000, respectively. Therefore, it is estimated that hairy vetch green manure in fall oats-corn double cropping system can reduce nitrogen chemical fertilizer on corn as much as 50-100 kg/ha although its N effect is much lower than the N effect of hairy vetch green manure in corn single cropping of which N effect is over 200 kg/ha.

• 한국HCI학회:학술대회논문집
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• 2009.02a
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• pp.1363-1373
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• 2009

본 연구는 두 집단지성의 가장 대표적인 서비스인 네이버 지식iN과 위키피디아의 구조적, 경험적 차이를 바탕으로 생산의 차원에서 생산 주기, 생산 참여자, 생산물의 모델을 설정하고, 새롭게 탄생하는 지식을 중심으로 검증함으로써 최종 지식 소비 행위를 반영한 각각의 종합모델을 도출하였다. 우리는 웹에서 집단지성의 일상화를 확인할 수 있다. 지식 획득 매체가 매스미디어에서 인터넷으로 변화하는 과정에서 등장한 포털 및 검색사이트는 지식의 생산이 전문가패러다임에서 소비자 중심으로 재편될 수 있는 가능성을 열어주었다. 그리고 이러한 생산 방식의 변화는 '지식'의 개념 역시 변화시키고 있다. 즉, 집단지성이라는 새로운 웹2.0의 현상이 지식생산방식을 변화시키고 변화된 지식생산방식은 '지식'자체를 변화시킨다는 이론적 가설을 도출할 수 있는 것이다. 본 연구는 이러한 새로운 현상들을 분석하기 위해서는 먼저 보다 엄밀하게 집단지성의 개념을 규정할 필요성에 출발하였다. 현재 집단지성이라는 이름으로 불리면서 급격히 성장하고 있는 위키 방식의 인터넷 서비스와 지식검색 방식의 인터넷 서비스를 비교함으로써 보다 정교한 집단지성의 모델을 구축하고자 하였다. 위키형 집단지성과 지식검색형 집단지성의 차이점은 경험적으로도 뚜렷하게 확인할 수 있다. 본 연구는 이러한 경험적 차이와 기존의 문헌에서 밝혀진 사실들을 바탕으로 두 서비스의 지식생산 방식을 생산플로우, 생산참여자 성향, 생산물(지식)의 성향과 같이 세 영역으로 나누어 각각의 가설 모델을 설정하고 이 모델을 선정된 질의어를 바탕으로 검증한 뒤에 최종적인 모델을 도출하는 방식으로 진행되었다. 지식검색형 집단지성은 '질문-답변-채택'의 구조이고, 그 구조 속에서 '질문기-답변기-순서화기'를 거쳐 하나의 지식 덩어리인 'K-let'을 생산한다. 생산된 'K-let'들은 지식검색서비스의 데이터베이스에 축적되고, 이는 공통된 질의어를 기준으로 소비자들에 의해서 검색되어 소비된다. 하나의 질문에 대해 여러 개의 답변들이 존재하고, 답변자의 성향은 크게 전문성과 체계성을 바탕으로 한 전문가형 답변자와 경험적이고 의견지향적인 대화형 답변자로 나눠진다. 다수의 네티즌들의 참여에 의해서 지식의 생산이 진행되므로 질문의 성향 역시 사실, 의견, 경험 등 다양한 스펙트럼을 가지는 모델로 설정하였다. 반면에 위키형 집단지성은 개방형 플랫폼을 바탕으로 한 백과사전의 형식이며, 이러한 형식 속에서 최초의 개념어 등록과 다수의 편집활동을 거치면서 완성되지 않는 하나의 아티클인 'W-let'을 생산한다. 이러한 'W-let'은 생성 초기에 소수에 의한 활발한 내용 입력 활동으로 어느 정도의 안정화를 거친 후에는 꾸준한 다수의 수정활동을 통해서 'W-let'의 생명력을 유지함으로써 지식의 실제적인 변화를 반영한다. 생산된 'W-let'들은 위키형 집단지성 서비스의 데이터베이스에 축적되고, 이것들은 내부링크를 통해서 모두 연결되어 있다. 백과사전 형식으로 하나의 개념어를 설명하는 하나의 아티클은 오로지 사실적인 지식들로만 구성되나 내부링크와 외부링크를 통해서 다양한 스펙트럼을 가지는 모델로 설정하였다. 위와 같이 설정된 모델을 바탕으로 공통된 질의어 및 개념어를 선정하여 각각의 서비스에 노출시켰다. 이를 통해서 얻어진 각 서비스의 데이터베이스에 축적된 모든 데이터들 중에서 일정한 기간을 기준으로 각각의 모델 검증에 필요한 데이터를 추출하여 분석하는 방식으로 진행되었다. 그 결과 지식검색형 집단지성에서는 '질문-답변-채택'의 생산 구조 속에 다수가 참여하여 질문-채택답변-기타답변으로 배열되어 있는 완성된 형태의 K-let들을 지속적으로 생산하며 비슷한 성향을 가진 K-let들이 반복적으로 생산되어 지식검색 데이터베이스에 누적된다. 지식 소비자들은 질의어 검색을 통해서 다양한 K-let들을 선택하여 비교, 검토한 후에 선택된 K-let들의 배열은 해체되어 소비자들에 의해서 재배열됨을 발견할 수 있었다. 이에 지식검색형 집단지성이란 다수의 의해서 생산되고 누적된 지식들이 소비자의 검색과 선택에 의해 해체되어 재배열되는 지식의 맞춤화 과정이라고 정의내릴 수 있었다. 반면에 위키형 집단지성에서는 '내용입력-미세수정' 구조 속에서 생명력 있는 W-let을 생성한다. W-let은 백과사전처럼 정리되어 내부링크를 통해서 서로 연결되고, 외부링크를 통해 확장되고, 지식소비자들은 검색을 통해 최초의 W-let에 도달한 후에 링크를 선택함으로써 지식을 확장시킴을 검증할 수 있었다. 따라서 위키형 집단지성이란 다수의 의해서 생산되고 정리된 지식들이 소비자의 검색과 링크에 의해 무한히 확장되는 지식의 확대 재생산되는 과정이라고 정의 내릴 수 있다. 결국, 현재의 집단지성이란 지식이 다수의 참여로 생산됨으로써 개인에게 맞춤화되고, 끊임없이 확대 재생산되는 과정을 의미한다. 그리고 이러한 집단지성의 방식은 지식이라는 현재의 차원을 넘어서 정치, 경제를 비롯한 사회의 전 영역으로 점차적으로 확대되어갈 것이다. 앞으로 연구들은 두 가지 모델이 혼재되어 있는 현재의 집단지성이 어떠한 새로운 모델을 만들면서 다른 영역으로 확장되어갈 것인지에 대해서 초점을 맞춰 나가야할 것이다.

• Journal of the Korean Society for Marine Environment & Energy
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• v.18 no.2
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• pp.94-101
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• 2015

To mitigate the greenhouse gas emission, many carbon capture and storage projects are underway all over the world. In Korea, many studies focus on the storage of $CO_2$ in the offshore sediment. Assurance of safety is one of the most important issues in the geological storage of $CO_2$. Especially, the assessment of possibility of leakage and amount of leaked $CO_2$ is very crucial to analyze the safety of marine geological storage of $CO_2$. In this study, the leakage of injected $CO_2$ through fault was numerically studied. TOUGH2-MP ECO2N was used to simulate the subsurface behavior of injected $CO_2$. The storage site was 150 m thick saline aquifer located 825 m under the continental shelf. It was assumed that $CO_2$ leak was happened through the fault located 1,000 m away from the injection well. The injected $CO_2$ could migrate through the aquifer by both pressure difference driven by injection and buoyancy force. The enough pressure differences made it possible the $CO_2$ to migrate to the bottom of the fault. The $CO_2$ could be leaked to seabed through the fault due to the buoyancy force. Prior to leakage of the injected $CO_2$, the formation water leaked to seabed. When $CO_2$ reached the seabed, leakage of formation water stopped but the same amount of sea water starts to flow into the underground as the amount of leaked $CO_2$. To analyze the effect of injection rate on the leakage behavior, the injection rate of $CO_2$ was varied as 0.5, 0.75, and $1MtCO_2/year$. The starting times of leakage at 1, 0.75 and $0.5MtCO_2/year$ injection rates are 11.3, 15.6 and 23.2 years after the injection, respectively. The leakage of $CO_2$ to the seabed continued for a period time after the end of $CO_2$ injection. The ratios of total leaked $CO_2$ to total injected $CO_2$ at 1, 0.75 and $0.5MtCO_2/year$ injection rates are 19.5%, 11.5% and 2.8%, respectively.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.17 no.3
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• pp.188-201
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• 2005

This is the first part of a two-part paper which describes comparison of reliability design methods by application to Donghae Harbor Breakwaters. This paper, Part 1, is restricted to stability of armor blocks, while Part 2 deals with sliding of caissons. Reliability design methods have been developed fur breakwater designs since the mid-1980s. The reliability design method is classified into three categories depending on the level of probabilistic concepts being employed. In the Level 1 method, partial safety factors are used, which are predetermined depending on the allowable probability of failure. In the Level 2 method, the probability of failure is evaluated with the reliability index, which is calculated using the means and standard deviations of the load and resistance. The load and resistance are assumed to distribute normally. In the Level 3 method, the cumulative quantity of failure (e.g. cumulative damage of armor blocks) during the lifetime of the breakwater is calculated without assumptions of normal distribution of load and resistance. Each method calculates different design parameters, but they can be expressed in terms of probability of failure so that tile difference can be compared among the different methods. In this study, we applied the reliability design methods to the stability of armor blocks of the breakwaters of Donghae Harbor, which was constructed by traditional deterministic design methods to be damaged in 1987. Analyses are made for the breakwaters before the damage and after reinforcement. The probability of failure before the damage is much higher than the target probability of failure while that for the reinforced breakwater is much lower than the target value, indicating that the breakwaters before damage and after reinforcement were under- and over-designed, respectively. On the other hand, the results of the different reliability design methods were in fairly good agreement, confirming that there is not much difference among different methods.

• Childhood Kidney Diseases
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• v.4 no.1
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• pp.84-91
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• 2000

Purpose: To improve the recovery of growth deficit after renal transplantation in children, we analysed the factors affecting height growth after renal transplantation. Methods: We reviewed medical records of fifty-six children in whom height data were available for three years after transplantation. All height data were converted into Z-scores. We analyzed the effects of sex, age at transplantation, cumulative mean steroid dose for 3 years, serum creatinine levels, height at transplantation, donor source and history of prior dialysis on patients' z-scores and delta Zs. Results: The Z-scores at transplantation were lower in patients of younger age (P=0.007). When baseline Z-scores were lower, the delta Zs were higher (P<0.01), but the Z-scores after transplantation were still lower (P<0.001). According to the analysis of the partial correlation coefficients, Z-scores and delta Zs at 1 year after transplantation were higher in groups of younger age and of lower steroid dosages (P<0.05). The delta Zs at 6 month and 1 year after transplantation were lower in the group with abnormally higher serum creatinine (P<0.05). There was no difference in Z-scores between groups of different genders, donor sources, and histories of previous dialysis. Conclusion: The children of younger age, on lower steroid dosage, with less growth retardation at transplantation, and with normal graft function had better height growth recoveries after renal transplantation.

• Journal of Chest Surgery
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• v.36 no.4
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• pp.261-266
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• 2003

Background: Surgery of abdominal aortic aneurysm revealed high operative mortality. We reviewed our 11-years' experiences of abdominal aortic aneurysm operation and wish to obtain information on the treatment. Material and Method: From Jan. 1990 to Dec. 2000, 48 patients were operated due to abdominal aortic aneurysm in Yonsei Cardiovascular Center Mean age was $62.8{\pm}12.7$ and there were 40 males and 8 females. Among 48 patients, nine patients had ruptured abdominal aortic aneurysm, and mean aneurysm diameter of non-ruptured cases was $8.8{\pm}2.4$cm. Result: There were 6 early deaths, and early mortality was 12.5%. Among 9 patients of preoperative aneurysm rupture, three patients died (33.3%), and among 39 patients of non-ruptured cases, 3 patients died (7.7%). Among preoperative variables, age (p<0.05), preoperative BUN level (p<0.05), and DM (p<0.05) were risk factors of early mortality. Among discharged 42 patients, 40 patients were followed up (f/u rate=95.2%) and mean follow up was $3.6{\pm}0.2$ years. During follow up periods, five patients died (late mortality=11.9%), and Kaplan-Meier survival analysis revealed $81.7{\pm}7.6$% survival rate at five and ten year. Linealized incidence of graft related event was 3.53% per patient-year. Conclusion: Surgical mortality of ruptured abdominal aortic aneurysm was higher than non-ruptured cases; therefore, early resection of the aneurysm can decrease the surgical mortality.

• Journal of Life Science
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• v.7 no.2
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• pp.142-148
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• 1997

This study was carried out to clarify seasonal changes of chemical compositions and their interrelation in leaves, shoots and berries treated with gibberellin($GA$_{3}$)for seedless grapes in ‘Delaware’grapevines. the clusters were dipped twice with 100ppm $GA_{3}$: 10 days befor and after the full bloom. The reaults obtained as follows; 1. Cumulative growth curve of berry fresh weight showed a double sigmoid curve and the characteristics of three distinctive growth stages(I, II, III)were weekened with $GA_{3}$ treatment. 2. while the contents of ash, total carbon, total nitrogen and total carbohydratd had little reation with edvelopment and ripeness of berries, those of total sugar and starch jad close relation, viz., they decreased with enlargement and maturity fo berries, but increased rapidly after harvest in leaves and shoots. Especially, total sugars in leaves and shoots decreased coincidently with starch-increasing in shoots at November. 3. The contents of total soluble solid and reducing sugar in berries increased rapidly at growth stage III, but those of total titratable acidity and organic acid decreased coincidently with sugar-increasing. 4. The berry-hardness increased until growth stage I, and then stagnated until gtowth stage II, and then increased rapidly at growth stage III. pH of berry-juice decreased until growth stageII, afterwards increased at growth stage III. 5. By correlation and path coefficient analysis between qualitative characters and the ratio of total soluble solid to titratable acidity($^{\circ}$Brix/Acidity), total correlation coefficients were all highly significant. Of these characters, pH and viscosity of berry-juice were positive, but brightness and hardness of berry, negative. The direct effect of pH on $^{\circ}$Brix/Acidity ratio, p4y=0.9090, was large positively and those of berry-hardness and juice-viscosity, p1y=0, 5938, median and, p2y=0, 3550, small, respectively. Direct effect of brightness was negatively small.