• 제목/요약/키워드: 뇌질환

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화열과 음허로 진단된 급성기 뇌질환 환자의 특성 비교 연구 (A Comparison on the General Characteristics of Acute Stroke Patients between Fire-Heat and Deficiency of Yin)

  • 김혜미;곽자영;조승연;신애숙;이인환;김나희;나병조;박성욱;정우상;문상관;박정미;고창남;조기호;김영석;배형섭
    • 대한중풍순환신경학회지
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    • 제10권1호
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    • pp.33-39
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    • 2009
  • Objects : This study propose to compare on general characteristics of acute stroke patients between Fire-Heat group and Deficiency of Yin group. Method : We recruited acute stroke patient within 4 weeks after stroke admitted to Department of Internal Medicine of Kyunghee University Oriental Medicial Center, Dongguk University Ilsan Oriental Medical Center, Kyungwon University Songpa Oriental Medical Centar and Kyungwon University Incheon Oriental Medical Center from April 2007 to August 2009. We investigate age, sex, type of stroke, past history, general characteristics, smoking, drinking alcohol, marriage sasang constitution, etc. Result : It was significant different in sex, smoking, dringking alcohol and marriage between Fire-Heat group and Deficiency Yin group. We need more cases for another result that could associate with diagnosis of stroke. Conclusion : We found that Fire heat group was more associated with lifestyle than deficiency yin group. Further study will be needed to analysis for the diagnosis and the treatments of stroke.

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중풍 환자의 심박변이도 특성에 대한 임상적 연구 (Clinical Study for Characteristics of Heart Rate Variability in Stroke Patients)

  • 이인환;신애숙;김나희;김혜미;심소라;김민경;조승연;나병조;정우성;문상관;박정미;고창남;조기호;김영석;배형섭;박성욱
    • 대한중풍순환신경학회지
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    • 제11권1호
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    • pp.1-8
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    • 2010
  • Objectives : We designed this study to investigate difference of heart rate variability(HRV) according to sex, age, acute or chronic phase, category of stroke, national institute of health stroke scale(NIHSS), lesion of stroke. Methods : 64 subjects were recruited from the patients admitted to the department of oriental medicine at East-West Neo Medical Center, Kyung Hee University from 1 September 2009 to 31 August 2010. We compared heart rate(HR), standard deviation of all normal P-P intervals(SDNN), low frequency(LF), high frequency(HF), LF/HF ratio. Results and Conclusions : 1. LF/HF ratio is significantly different between over-70 and below-70 of age. 2. SDNN is significantly different between acute and chronic stroke patients. 3. In sex, category of stroke, national institute of health stroke scale(NIHSS), lesion of stroke, there are no significantly different among the any values of heart rate variability(HRV).

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퇴행성 뇌질환 치료제의 연구개발 및 특허동향 분석 (A Study on the R&D Trend and Patent Analysis of Treatments for Degenerative Brain Diseases)

  • 손은수;손은화
    • 한국산학기술학회논문지
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    • 제12권10호
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    • pp.4411-4417
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    • 2011
  • 현대사회가 급속히 고령화됨에 따라 알츠하이머질환, 파킨슨병 등 퇴행성 뇌질환의 발생속도도 급증하고 있다. 퇴행성 뇌질환 대부분은 아직도 근원적인 치료가 불가능한 채 발병원인도 명확하지 않은 상태이나 최근 세포분자학적 기술 수준의 향상으로 퇴행성 뇌질환의 원인 규명 및 치료제 개발에 활기를 띠고 있다. 본 연구에서는 퇴행성 뇌질환 기작별 최근 치료제의 연구개발 동향과 국내외 기술동향을 조사 분석 하였으며, 과학계량학적 특허정보 분석을 통해 국가별 기술수준을 파악하고 기술개발 전망을 제시하였다.

퇴행성 뇌질환에서 뇌 자기공명영상 기반 인공지능 소프트웨어 활용의 현재 (Brain MRI-Based Artificial Intelligence Software in Patients with Neurodegenerative Diseases: Current Status)

  • 정소영;서종현;박호영;허훤;심우현;김상준
    • 대한영상의학회지
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    • 제83권3호
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    • pp.473-485
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    • 2022
  • 현대사회가 점차 고령화 사회가 됨에 따라 퇴행성 뇌질환의 발병률이 증가하고 있으며, 이러한 퇴행성 뇌질환에 관한 많은 연구들이 이루어지고 있다. 퇴행성 뇌질환의 진단에서 영상분석은 영상표지자로서 중요한 역할을 하고 있다. 영상분석에서 객관적이고 일관성 있는 평가는 퇴행성 뇌질환의 조기 진단 및 정확한 진단에 중요하다. 이에 다양한 퇴행성 뇌질환과 관련한 영상연구에 자기공명영상(이하 MRI)을 이용한 인공지능이 조기 진단과 최적의 치료 방향 계획 및 결정에 도움이 될 가능성을 보여주었다. 특히 MRI 기반의 뇌용적 측정과 분획화 및 특성을 포착하는 인공지능 소프트웨어들이 개발되고 연구되기 시작했다. 본 고찰에서는 우리나라에서 퇴행성 뇌질환과 관련하여 사용되고 있는 인공지능 소프트웨어의 현재 상황과 향후 인공지능 소프트웨어의 퇴행성 뇌질환 연구에의 활용, 그리고 인공지능 소프트웨어의 한계에 대해서 다루고자 한다.

중풍 뇌 질환의 한 방향 협진에 관한 임상적 고찰 (Clinical Observation on East-West Integration Treatment in Stroke and Brain Disease)

  • 신애숙;이인환;김나희;김혜미;김민경;심소라;조승연;박성욱;박정미;배형섭;고창남
    • 대한중풍순환신경학회지
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    • 제11권1호
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    • pp.9-17
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    • 2010
  • Objectives : This study was aimed to evaluate the current status of East-West integrated treatment in stroke and brain disease and to discuss further plans. Methods : The medical records of patients who visited the stroke and brain disease center at Kyung Hee University, East-West Neo Medical Center from May 2006 to August 2010 were evaluated. The general characteristics of patients who underwent integrated treatment, trend in the number of cross referrals were initially evaluated. Later major disorders, the reasons of referrals and the number of visits in outpatients were analyzed. Results : 1. 3496 patients were referred from the eastern medical hospital to the western medical hospital and 2440 patients from the western medical hospital to the eastern medical hospital. The number of patients reached a peak alter the opening of the hospital and has decreased from then on. Referrals of female patients were more than those of male patients and patients over 50 years old were the most. 2. Admitted patients with stroke of chronic stage were most commonly referred from the eastern medical hospital to the western medical hospital and cerebral infarction was most common from the western medical hospital to the eastern medical hospital. Among the outpatients cerebral infarction topped from east to west, and stroke of chronic stage from west to east. 3. 36.6% of the patients from east to west received integrated treatment more than 3 times and 28.6% from west to east. Headache was the second most common reason to be referred from west to east and 36.7% of patients didn't continue to have either of the treatment and 30.3% received eastern treatment only, Conclusions: According to this study, chronic stroke management was successfully performed in the outpatient clinic in the form of East-West integration treatment. Further research on other diseases such as headache is recommended.

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한열변증에 따른 중풍 환자의 제반특성 비교 (The Comparison on the General Characteristics of Acute Stroke Patient between Heat pattern group and Cold pattern group)

  • 김민경;이인환;신애숙;김나희;김혜미;심소라;나병조;조승연;박성욱;정우상;문상관;박정미;고창남;조기호;김영석;배형섭
    • 대한중풍순환신경학회지
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    • 제11권1호
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    • pp.18-25
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    • 2010
  • Object : This study was conducted as part of the national project to standardize stroke diagnosis in Korean medicine. In this study, we aimed to evaluate the characteristics of acute stroke between heat pattern group and cold pattern group. Methods : We recruited stroke patients from 5 universities(Kyung-Hee University oriental medical center, Kyung-Hee University East-West Neo medical center, Kyungwon university lncheon oriental medical center, Kyungwon university Songpa oriental medical center and DongGuk university llsan oriental medical center) from April, 2007 until February, 2010. We diagnosed them and selected 463 heat pattern patients and 182 cold pattern patients. Results : We find that the risk factor of smoking, alcohol, diet(prefer to meat) are more associated with the heat pattern group. On the other hand, inflammation history in recent 3 months and diet(prefer to sea food) are more associated with the cold pattern group. RBC, Hg, Hct, TG, CK and Cl are more related to the heat pattern group. CPT, total cholesterol and HDL are more related to the cold pattern group. Tae-eum type takes high distribution of the heat pattern group, and So-eum type takes high distribution of the cold pattern group. Conclusions : This study provides evidence that the heat pattern group have more risk factor than the cold pattern group.

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안전백호탕 가미방으로 호전된 상열감 및 안면홍조를 호소하는 환자 1례 (A Case Report of Hot Flushing Treated with Gami Ahnjeonbaekho-tang)

  • 김연진;양승보;이보윤;이동혁;조승연;박성욱;고창남;박정미
    • 대한중풍순환신경학회지
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    • 제16권1호
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    • pp.41-48
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    • 2015
  • ■ Objectives This clinical study is to report the effect of Korean medicine on patient with hot flushing ■ Methods A patient who suffered from hot flushing was treated with herbal medicine 'Gami Ahnjeonbaekho-tang', acupuncture, moxibustion and pharmaco-acupuncture. Degree and frequency of flushing were measured. Digital Infrared Thermal Imaging (DITI) was used to estimate the temperature of skin surface for the outcome assessment ■ Results After taking Gami Ahnjeonbaekho-tang, degree and frequency of hot flushing reduced and skin temperature of patient was reduced on DITI. ■ Conclusion This clinical case study showed the effect of Korean medicine on hot flushing

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중풍 용어 표준화 및 영번역 방안에 관한 연구 (A Study For Standardization of Stroke Terminology)

  • 이주아;이정섭;강병갑;고미미;문태웅;고호연;박성영;정희;방옥선
    • 대한중풍순환신경학회지
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    • 제11권1호
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    • pp.76-81
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    • 2010
  • Background : Currently, the absence of a unified terminology and proper translation about Traditional Korean Medicine is a problem that should be solved. Although Traditional Korean Medicine has undergone steady growth in popularity during the past years, the Westerner's poor access to information has been drawback to its reception in the West. Objective : This research is aimed to seek system for standardization of stroke terminology and proper translation into English. Conclusion : We proposed the method of making unified terminology and translation about stroke in Traditional Korean Medicine.

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감각장애를 동반한 Thalamic Ataxia 환자 치험 1례 (A Case Report of an Ataxia Patient with Sensory Loss Diagnosed with Thalamic Infarction)

  • 이보윤;이현중;이동혁;두경희;김수경;조승연;박정미;고창남;배형섭;박성욱
    • 대한중풍순환신경학회지
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    • 제15권1호
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    • pp.39-49
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    • 2014
  • This report is about a case of an ataxia patient with sensory loss diagnosed with thalamic Infarction. The patient had symtoms of gait disturbances and dysmetria. We used Korean medicine treatment modalities including acupunture, electroacupuncture, moxibustion and herb medicines. The improvement of ataxia was evaluated by International Cooperative Ataxia Rating Scale and Balance master system. After treatment, decreased scores of International Cooperative Ataxia Rating Scale and change of the trace of Balance master system showed that symtoms of ataxia were improved. Sensory deficits and other conditions were also getting better. This report suggests that Korean medicine could have a therapeutic effect for Thalamic ataxia.

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