• Title/Summary/Keyword: 노화 효과

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The Effect of Middle-aged People's Retirement Preparation on Successful Aging : Focusing on the mediating effect of social support (중장년층의 노후 준비가 성공적 노화에 미치는 영향 : 사회적 지지의 매개효과를 중심으로)

  • Seung-Gwon Jung;Hyun-Seung Park
    • Industry Promotion Research
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    • v.8 no.3
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    • pp.69-78
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    • 2023
  • Based on the perception that integrated retirement preparation in various areas is needed in preparation for increased old age, this study aims to identify the status and characteristics of retirement preparation of middle-aged people and reveal the relationship with successful aging. In addition, it aims to find out the mediating effect of social support in the relationship between retirement preparation and successful aging for the middle-aged. To confirm this, 1,037 men and women aged 50 to 64 who responded to the third, fourth, and fifth additional surveys of the Korean Retirement & Income Study (KReIS) conducted by the National Pension Research Institute were analyzed. When the preparation of middle-aged people for retirement affects successful aging, bootstrapping with IBM SPSS 26 Process Macro Model 4 was conducted to verify the mediating effect of social support. As a result of verifying the significance of independent variables on the parameters, preparation for retirement was positively (+) significant. In other words, it was verified that the higher the preparation for retirement, the higher the social support. Furthermore, it was discovered that social support, an independent variable, had a significant impact on successful aging, and social support, an independent variable, had a significant impact on successful aging. The results of this study suggest the need for social support for successful aging through the preparation of middle-aged people for retirement. It is intended to derive policy implications for preparing for retirement and provide them as basic data to increase the level of successful aging.

A Key Role for the Conserved Nutrient-Sensing TOR Pathway in Aging (노화에 있어서의 영양소 감지 TOR 경로(Nutrient-Sensing TOR Pathway)의 역할)

  • Ahn, Ji-Yun
    • Bulletin of Food Technology
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    • v.23 no.3
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    • pp.400-406
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    • 2010
  • TOR(target of rapamycin)은 모든 진행세포에서 성장과 대사를 조절하는 영양소 인식 단백질 인산화효소(nutrient-sensing protein kinase)로 곤충, 효모, 마우스를 이용한 실험 결과 TOR 신호 전달계는 노화를 조절하는 것으로 밝혀졌다. 또한 TOR은 식이제한 시 나타나는 다양한 보호 효과(생명 연장, 노화 관련 질환 발병 억제 등)의 강력한 중계자로 알려졌다. 본 리뷰에서는 TOR 신호 전달계가 어떻게 노화를 지연시키는가에 대해 다루고자 한다. 노화조절인자로서의 TOR 신호전달계 조절 기전 구명은 매우 중요한 연구 분야이며 노화 관련 질환을 타겟으로 한 제약 및 건강기능식품의 개발을 통해 인간 수명 연장의 꿈을 성취하는 것을 조금 더 앞당길 수 있을 것으로 사료된다.

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Bacillus polymyxa No.26의 생전분 당화형 $\beta$-amylase를 이용한 떡의 노화억제효과

  • 손천배;이상미
    • Proceedings of the Korean Society of Postharvest Science and Technology of Agricultural Products Conference
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    • 2003.10a
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    • pp.215.1-215
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    • 2003
  • Bacillus polymyxa No. 26이 생산하는 생전분 당화형 $\beta$-amylase를 쌀가루 반죽시 첨가하여 45$^{\circ}C$에 5시간 둔 후 증자하여 제조한 절편을 4$^{\circ}C$ 저온실에 40시간 동안 저장하면서 기계적 검사와 관능검사에 의하여 물성과 맛을 측정하고 효소 무 첨가의 경우와 비교하여 노화억제 효과를 조사하였다. 기계적 검사시 효소 무 첨가구의 경우는 40시간까지도 굳지 않아 노화되지 않았으며, 경도, 점착성, 씹힘성에서도 큰 차이를 보였다. 관능검사시에도 경도, 촉촉함성, 단맛에 있어서 효소 첨가효과가 크게 나타났으며 떡의 제조 시 효소의 이용으로 설탕첨가를 생략할 수 있고 소화성과 맛을 좋게하므로서 품질을 향상시킬 수 있었다.

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Lightning Impulse Breakdown Voltage Characteristics for 22.9kV TR CNCV-W Power Cable Before and After Cyclic Aging for 14days (14주기 열화에 따른 22.9kV TR CNCV-W 전력케이블의 Lightning-Impulse 파괴전압 특성분석)

  • Kim, We-Young;Heo, Jong-Cheoi;Park, Tae-Gone
    • Proceedings of the KIEE Conference
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    • 2006.07c
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    • pp.1505-1506
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    • 2006
  • XLPE 절연 전력케이블의 제조과정에서 발생하는 가교부산물을 제거할 목적으로 14주기노화를 실시한다. 이 과정에서 가교부산물이 제거되는 효과도 있지만 열에 의한 구조적 결함도 생기게 되며, 이들 모두가 뇌충격파괴전압에 영향을 준다. 22.9kV 트리억제형(TR CNCV-W) 케이블에 대하여 14주기노화 전과 후의 파괴전압을 분석하였으며, 전반적으로 노화과정이 파괴전압을 감소시키는 결과를 보였으나 60 $mm^2$ 케이블은 상승효과와 감소효과가 비슷하게 작용하는 것으로 나타났다.

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Anti-aging Effects of Sweroside Isolated from Nymphoides indica (어리연꽃으로부터 분리한 Sweroside의 항노화 효과)

  • Kim, You Ah;Kim, Dong Hee;Park, Chae Bin;Park, Tae Soon;Park, Byoung Jun
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.44 no.2
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    • pp.103-110
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    • 2018
  • To develop a new functional agent for cosmetics, we investigated the anti-aging activities in fibroblasts using sweroside isolated from Nymphoides indica. The anti-aging effect of sweroside was validated in CCD-986sk cells. Results showed that sweroside inhibited expressions of UVB-induced ROS and increased pro-collagen. Furthermore, sweroside had inhibited MMP-1 expression. Taken together, the results suggested that sweroside has considerable potential as a new cosmetics ingredient with an anti-aging effect.

Photo-aging regulation effects of newly bred Green ball apple (신품종 그린볼 사과의 광노화인자 조절효과)

  • Lee, Eun-Ho;Lee, Seung-Yeol;Jung, Hee-Young;Kang, In-Kyu;Ahn, Dong-Hyun;Cho, Young-Je
    • Journal of Applied Biological Chemistry
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    • v.63 no.1
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    • pp.75-82
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    • 2020
  • In this study, extracts from the Green ball apple peel (GBE) and the newly bred green ball apple from Korea showed inhibition effects on photo-aging factor regulation associated with skin aging. To investigate the inhibition effect on photo-aging factor regulation in skin, GBE was treated with UVB to induce photo-aging related factors in CCD986sk fibroblast cells. Photo-aging factor regulation effects showed that GBE inhibited UVB-stimulated matrix metalloproteinase (MMP)-1 and MMP-9 protein synthesis in collagen type I alpha 2 chain (COL1A2), MMP-1, MMP-9, and tissue inhibitors of metalloproteinase (TIMP)-1 protein expression. The expression of COL1A2 and TIMP-1 protein was significantly increased. The mRNA expression levels of COL1A2, MMP-1, MMP-9, hyaluronan synthase (HAS)2, transforming growth factor (TGF)-β, and TIMP-1 were decreased by GBE. The expression of TIMP-1 and TGF-β, which are regulators involved in matrix metalloproteinase and type I procollagen expression, was found to increase with increasing expression of COL1A2. The expression of HAS2, which is involved in the production of hyaluronic acid, one of the structural proteins constituting the skin, was also confirmed. Therefore, GBE showed excellent efficacy against photo-aging factor regulation and could be used as functional material to prevent and treat skin aging.

The SOC Strategy Intervention Program for Successful Aging of the Elderly: A Pilot Study (노인의 성공적 노화를 위한 SOC전략 중재프로그램의 효과: A Pilot Study)

  • Shin, Ga-In;Woo, Ye-Shin;Park, Dasol;Park, Hae Yean
    • Therapeutic Science for Rehabilitation
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    • v.8 no.4
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    • pp.33-39
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    • 2019
  • Objective : The purpose of this study is to examine the effect of successful intervention program on SOC strategy and successful aging of the elderly. Methods : Three elderly individuals aged ${\geq}65$ living in W-si, Gangwon-do, were included. A successful aging program using an SOC strategy was conducted twice a week for 6 sessions. To verify the effectiveness of the program, the Korean versions of the SOC scale and the successful aging scale were used. Descriptive statistics were used for general characteristics, and the Wilcoxon signed-rank test was used to compare successful aging and SOC strategies. Results : After 3 weeks for successful aging program, the SOC strategy levels of the subjects were constant or improved. In addition, the average score of successful aging level increased by 11.4 points. Conclusion : This study show that the successful aging program using the SOC strategy improved the level of SOC strategy and the level of successful aging. The results of this study can be used as basic data to develop programs that can promote SOC strategy and successful aging. Also, the result of this study can be used as a basic data for the development of guidelines for occupational therapists in the future.

Predictors of Successful Aging in Community-dwelling Elders and Mediation Effect of Transcendence (지역사회 노인의 성공적 노화 예측요인과 초월감의 매개효과)

  • An, Ji Won
    • The Journal of the Korea Contents Association
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    • v.16 no.4
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    • pp.582-593
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    • 2016
  • The purpose of this study was to identify predictive factors of successful aging and to determine mediating effect of transcendence between successful aging and influencing factors of community-dwelling elders in Korea. 162 elders were participated in this study who visited seniors welfare center and senior citizen center. Data were analyzed by PASW 18.0 for t-test, Pearson's correlation coefficients and hierarchical regression analysis. Transcendence, parent-child relationship, depression, spirituality and perceived economic status were statistically significant influencing factors, explained 77% of successful aging in community-dwelling elderly. The mediating role of transcendence was identified about parent-child relationship, depression, spirituality and perceived economic condition. The study findings demonstrated that transcendence was significant variable affecting successful aging. The variables affecting successful aging such as transcendence, parent-child relationship, depression, spirituality, perceived economic status can be utilized for nursing strategies to successful aging in community-dwelling elders.

Effects of the Elderly's Human, Economic and Cultural Capitals on Successful Aging: Focused on Mediating Effects of Engagement in Social Activities (노인의 인적·경제·문화자본이 성공적 노화에 미치는 영향: 사회활동참여의 매개효과를 중심으로)

  • Han, Hee Kyung
    • 한국노년학
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    • v.38 no.4
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    • pp.981-997
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    • 2018
  • This paper verifies if the engagement in social activities mediates the effects of human, economic and cultural capitals on successful aging in elderly citizens. The questionnaire survey data collected from 356 elderly citizens aged 65 and over in Busan undergoes structural equation modeling for analysis. The analysis highlights the following. First, human and cultural capitals influence social engagement activities whereas economic capital does not. Second, economic capital affects successful aging whereas human and cultural capitals do not. Third, engagement in social activities impacts on successful aging. Fourth, engagement in social activities mediates the effects of human, economic and cultural capitals on successful aging. Based on these findings, this paper makes suggestions for improving the capitals and social activities of the elderly for successful aging.

The Relationship between Aging Anxiety and Psychological Well-Being in Mid-life Adults: The Moderated Mediation Effect of Cognitive Flexibility and Subjective Economic Status (중년의 노화불안과 심리적 안녕감의 관계: 인지적 유연성과 주관적 경제수준의 조절된 매개효과)

  • Yang, Ok-Ji;Lee, Su-Lim
    • The Journal of the Korea Contents Association
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    • v.20 no.7
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    • pp.491-502
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    • 2020
  • This study was aimed to verify moderated mediation effect between cognitive-flexibility and subjective economic status in the process that aging anxiety have an effect on psychological well-being. For this, online survey was conducted to 317(M:159, F:158) adults who ranged from 40 to 64 years old. Survey was conducted from 2017.9.3. to 9.28. Correlation analysis, regression analysis, and significant test was done through SPSS 21.0 and SPSS Macro. First, the analysis showed that meaningful correlation was found among aging anxiety, cognitive flexibility, subjective economic status and psychological well-being. Secondly, cognitive flexibility was found to have meaningful partial mediation effect(β = .530, p < .001) in the relationship between aging anxiety and psychological well-being. Thirdly, subjective economic status was found to have a meaningful moderation effect(β = .080, 𝜟R2=.006, p <.05) in the relationship between cognitive flexibility and psychological well-being. Fourthly, verification result by SPSS Macro showed that, mediation effect of cognitive flexibility and subjective economic status was existent in the relationship of aging anxiety and psychological well-being. Lastly, implications and limitations of this study and suggestions for future studies were discussed.