• Journal of Life Science
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• v.29 no.6
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• pp.705-711
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• 2019

Benign prostatic hyperplasia (BPH) is the most common urogenital disorder in men, benign tumor and is a typical disease deteriorating the quality of old men's lives, and its prevalence increases with age. Though the molecular pathogenesis of BPH has not yet been clearly revealed, it is known that the variation and aging of the endocrine including sex hormone may cause BPH. Especially the hypertrophy of the prostate cell by the formation of the excessive dihydrotestosterone (DHT) is estimated to cause BPH. If testosterone exists excessively in blood, a lot of DHT is produced in prostate by $5{\alpha}-reductase$. Thus, in this study we tried to analyze haematological change and histopathological change by using the model rat with BPH caused by hypodermic injection of testosterone to prove the effect of Houttuynia cordata extracts on BPH. Rats were divided into four experimental groups: no treatment group (N), the testosterone injection and D.W treatment group (DO), the testosterone injection and Houttuynia cordata treatment group (HO) and testosterone injection and finasteride treatment group (FO). Prostate weight, volume and weight ratio in the HO and FO groups were significantly lower than the DO group. Testosterone and DHT levels in the HO group were significantly lower than the DO group. The HO and FO groups showed trophic symptoms and were lined by flattened epithelial cells, thus, the stromal proliferation is relatively low as compared to the DO group. These results suggest that Houttuynia cordata may control benign prostatic hyperplasia.

• Journal of Industrial Convergence
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• v.18 no.6
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• pp.139-146
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• 2020

Care of people with severe disabilities requires care throughout their life cycle compared to non-disabled families. For this reason, carers of severely handicapped families are highly likely to have negative feelings throughout the family as well as daily stress. Disabled families also have a high rate of experiencing difficulties between non-disabled children or married couples in life centered on the disabled. In particular, the rapid aging in Korea affects the lives of the elderly disabilities along with the aging of the caregivers. The study explored alternatives to realistic support through the past and present experiences of caregivers with disabilities through qualitative research methods, and derived hopes and expectations for the future as follows.First, after confirming the disability for infants and toddlers with disabilities, information about the support system or system is provided from the rating agency. Second, providing "customized care support" suitable for the type of disability or individual characteristics at the social, political, institutional, and economic levels. Third, the provision of programs for non-disabled children and the provision of healing programs only for families with disabilities or those with disabilities. Fourth, the provision of spaces and programs that provide rest and rest for adults with disabilities. Fifth, the application of a long-term care system for the elderly reflecting the aging age of the disabled and institutionalization of community care for the disabled. The research is meaningful in that it presents discussion points for improving the quality of life of adults and the elderly with disabilities.

• Journal of the Korea institute for structural maintenance and inspection
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• v.20 no.2
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• pp.18-25
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• 2016

Bascule bridge, with its use to help vessels ply, has a several examples overseas of being serviced for more than decades years by careful maintenance, admitted its significance as landmarks for its rareness. Yeongdo Bridge, the sole bascule bridge in Korea was reconstructed in 2013 after being demolished because of its corrosion and aging, and now operates once in a day. Recently, safety inspections are executed thanks to demands getting higher for maintenance and safety of bridges, but measurement and analysis about bascule bridges are scarce. This study includes the analysis of the bascule bridge's behavior such as stress, vibration and reaction in normal condition and while it lifts up, based on measurement. We expect that this study will be used as an initial data to compare and confirm bridge's changes as service year and the number of operation increase.

• The Journal of the Korea Contents Association
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• v.19 no.10
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• pp.560-567
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• 2019

South Korea, which has entered an aged society, is about to enter a super-aged society in 2025. With the increase of an aging population, traffic accidents by aged drivers have been settled as a social problem. Now, when Korea is facing a super-aged society to come, a study was conducted to prevent traffic accidents that occur while the elderly people are driving through a disaster prevention design. For theoretical research, this study examined the concept and necessity of disaster prevention design, the present condition of an aged society, aged drivers' physical and cognitive characteristics, and the policies related to the forms of traffic lights the elderly people see. In addition, to propose the design, this study investigated and analyzed the traffic safety forms and colors of the International Standards Organization and proposed the first and second forms of the design of traffic lights for the gradual improvement of the traffic lights based on that. The first improved design form is a plan for displaying a triangle, an arrow with a large area, and a quadrangle in the lens of the head of the existing traffic lights, and the second improved design form is a plan for introducing a new traffic light head and forming the traffic light with a bigger triangle, an arrow with a large area and a quadrangular lens. Since it has a visually clearer form than the present traffic lights, it is expected that aged drivers who have physical and cognitive characteristics due to aging can secure better visibility and conspicuity and that they can make better reflex responses than they can now, also in the change of driving environment (rain and heavy snowstorm, etc.). In addition, it is expected that this study would be a preceding study to prepare standard guidelines on traffic safety signs other than traffic lights to be prepared for the super-aged society.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.44 no.3
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• pp.349-362
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• 2018

An annual plant, Eclipta prostrata (Linn) is a member of the Asteraceae plant family and inhabited in tropical or subtropical regions of the world. Through many previous researches, E. prostrata has been extensively studied for its hepatoprotective effect, antivenom potential against viper venom, antioxidant, hair-growth, wound-healing efficacy and so on. In this study, for better understanding of the potential of E. prostrata as skin protectant, we conducted the experiments evaluating the antioxidant and antiaging efficacy. To this end, 50% ethanolic extract of E. prostrata and its ethyl acetate fraction were prepared and investigated. For the evaluation of antioxidant capacity of the samples, $FSC_{50}$ and $OSC_{50}$ were estimated. As a result, $OSC_{50}$ of ethyl acetate fraction was 2.7 times superior to $OSC_{50}$ of L-ascorbic acid, a well known antioxidant agent. Futhermore E. prostrata showed notable reactive oxygen species (ROS) scavenging effect and protective effect against $H_2O_2$ in the celluar level as well. Especially, in the $^1O_2$ induced hemolysis test, $64{\mu}g/mL$ of ethyl acetate fraction showed greater than 6 times increased retardation effect compare to control which means E. prostrata has remarkable antioxidant capacity. To validate the antiaging effect of the samples, we conducted elastase inhibition assay using elastase solution extracted from human skin fibroblasts, Hs68. As a result, $16{\mu}g/mL$ of each sample showed 6.8% and 14.0% of elastase inhibition respectively. Finally, antimicrobial activity of E. prostrata was assessed to validate the possibility as alternative preservative. From the result, ethyl acetate fraction showed oustanding antimicrobial activity as of methyl paraben, a well known chemical preservative. In conclusion, these results suggest that E. prostrata can be used as natural skin protectant or preservative as natural ingredient in food or cosmetics industry.

• The Journal of the Korea Contents Association
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• v.15 no.7
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• pp.643-654
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• 2015

The purpose of this study is to examine the implications of religious activities to longevity in a perspective of religious people in the ancient near east. The major sources of the study are the records of Adad-Guppi in the Neo-Babylonian Empire, prayers of Daniel in the Old Testament and records of Anna in the New Testament. The research method is a synchronic method based on final forms of the texts. Adad-Guppi lived for 104 years with temple-centered lives, fasting-like dedication, prayer and mission for the nation. Daniel fasted and prayed for the return of Jewish nation, and restoration of the city and the temple in Jerusalem, resulting in longevity of late eighties in the court of Babylon. Anna lived for more than 100 years old with her life mission for the messiah in spite of limitations of her times as an old widow. The implications of religious activities with temple-centered lives, fasting, prayer, and mission for the ages are understood to be beneficial to longevity in a perspective of the ancient near east.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.68 no.4
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• pp.262-275
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• 2023

This study aimed to assess the preferences of African, American, and Asian panels, in comparison to a Korean panel, for various Korean rice varieties, including three japonica, two indica, and one Tongil-type, all developed by the Rural Development Administration in Korea. Regarding rice appearance, most panelists, except for the Koreans, favored long and slender rice varieties like 'Hanyeol', 'Hyangyeol', and 'Amissal'. In contrast, the Koreans preferred wider varieties like 'Sindongjin' and 'Deuraehyang'. Notably, the overseas panelists consistently favored rice varieties with high appearance quality in sensory evaluations of cooked rice. Both overseas and Korean panelists strongly preferred the indica rice variety 'Hanyeol' in terms of appearance quality and sensory evaluations. However, Korean rice varieties like 'Amissal' and 'Sindongjin' scored high in appearance quality with overseas panelists but received low ratings in sensory aspects, including shape, stickiness, and taste, compared to those for 'Hanyeol'. This suggests that considering sensory characteristics is important when exporting Korean rice varieties. Regarding taste characteristics preferred by the panelists derived from the correlation analysis between taste traits, Africans preferred rice with a smooth texture and no stickiness, especially favoring long-grain rice. Americans leaned towards rice with a slightly firm texture, some stickiness, and late aging characteristics. Asians preferred rice with a smooth texture, low stickiness, and long-grain varieties. In contrast, Koreans favored round rice with a glossy appearance, a slightly firm texture, late aging traits, and some stickiness. These research findings can serve as valuable data for the development of rice varieties for overseas markets and are expected to contribute to securing competitiveness in international markets.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.42 no.4
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• pp.413-420
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• 2016

Hydroxy acid has been used to enhance anti-aging and skin moisturization by peeling effect on the skin stratum corneum, and thus it has been widely used in topical products and cosmetic products. Among them, the effect that appears most effectively in a short period of time has been reported to be effected by the pH of the cosmetic formulations. However, there are many difficulties in use due to irritation caused by pH and concerns about side effects. The purpose of this study was to evaluate the effect of applying cosmetics with (1) varying concentrations, (2) types and (3) pH of hydroxy acid on human skin. 22 healthy adults were stained with DHA (dihydroxyacetone) and DC (dansyl chloride) on the forearm, and the skin exfoliation effect was measured after application of the test products. (1) The application of GA (glycolic acid) increased the desquamation by concentration dependent. (2) the test product prepared with neutral pH showed no exfoliation effect. In contrast, SA (salicylic acid) showed a statistically significant exfoliation effect at both acidic pH and neutral pH. (3) The neutral pH SA showed excellent exfoliation effect on bot DHA and DC stained stratum corneum. These results suggest that it is possible to manufacture safe cosmetics without damaging the skin barrier, providing an opportunity to use cosmetics that are expected to exfoliate to people, whose skin is sensitive to pH.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.31 no.1 s.49
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• pp.121-125
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• 2005

Most of the cells, specially in the skin, free radicals and reactive oxygen species induced aging, accompanying with diseases. The pinaceae family is very familiar plant with Korean spirit. However, those plants were not estimated for natural products in manufactural process. We employed 4 different plants, Pinus koraienis S et Z. Pinus banksiana LAMBERT. Pinus rigida MILL. Pinus densiflora S. et Z. in pinceae family. The ethanol extracts were prepared for three different parts of plant, wood, bark and leaf, respectively. In this study, we carried out free radical and superoxide radical scavenging assay to investigate the anti-oxidative activity The bark and leaf part of plants showed similar anti-oxidant effect. L-ascorbic acid and $\alpha$-tocopherol at $10{\mu}g/mL$. Also we tried to investigate inhibitory effects of elastase activity in in vitro experiments on pinaceae plant extract as a matters for functional cosmetics. Among those plants, the bark of Pinus rigida MILL. and Pinus densiflora S. et Z. showed inhibitory effect. The cell viability was evaluated with MTT assay. The potential relationship was shown between the cell viability and anti-oxidant effect because the anti-oxidant effects were positively correlated wvith the cell growth in MTT assay. As the results in our experiments, we expect the potential activities of pinaceae as a material of functional cosmetics.

• The Journal of the Korea Contents Association
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• v.19 no.9
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• pp.271-279
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• 2019

The life expectancy of people has been steadily extended due to the improvement of living standards and the development of medical technology. Besides, the low birth rate and long life expectancy decrease the youth population while the elderly population is steadily increasing. Many elderly people have enough time and financial allowance, and the interest in health care is increased all over society. There are also increasing numbers of elderly people who exercise lightly in the playgrounds and parks such as running and walking. Outdoor fitness equipment that can be easily seen in neighbourhood parks, public spaces, etc. can be good health promotion tools that can be easily accessed in the daily life of the elderly. Outdoor fitness equipment Description Signs require a design that takes into account the declining vision of older users. Proper design is also important for the prevention of safety accidents in use. The purpose of this study is to find out the perception of the elderly about outdoor fitness exercise equipment sign system and to find the problem of recognition. To do this, we conduct user observation and interview surveys for the elderly. As a result, the emphasis of the caveat or problems with the size of the writing were pointed out, and it was necessary to explain the picture rather than the text. Also, there was a high demand for refraining from using foreign words, using universal words and including motor effects in signs. Based on the results of the user observation and interviews, we propose guidelines for the use of outdoor exercise equipment.