• Journal of Korean Ophthalmic Optics Society
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• v.20 no.2
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• pp.237-246
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• 2015

Purpose: The present study was conducted to reveal the correlation of structural denaturation and decrease of enzyme activity when the antioxidative enzymes, superoxide dismutase (SOD) and catalase (CAT) were repeatedly exposed to UV-B, and further investigate whether the denaturation and inactivation of those enzymes can be effectively blocked by using UV-inhibitory RGP lens. Methods: Each enzyme solution was prepared from the standardized SOD and CAT, and repeatedly exposed to UV-B of 312 nm for 30 minutes, 1 hour and 2 hours a day over 1, 2, 3, 4 and 5 days. Structural denaturation of SOD and CAT induced by repeat UV-B irradiation was confirmed by the electrophoretic analysis, and their enzyme activity was determined by the colorimetric assay using the proper assay kit. At that time, the change in structure and activity of the antioxidant enzymes directly exposed to UV-B was compared to the case that UV-B was blocked by UV-inhibitory RGP lens. Results: SOD exposed repeatedly to UV-B showed the polymerization pattern in the electrophoretic analysis when it repeatedly exposed for 30 min a day, however, the change of its activity was less than 10%. On the other hand, CAT repeatedly exposed to UV-B reduced size and density of the electrophoretic band which indicated a structure denaturation, and its activity was significantly decreased. In the case that the repeat exposure time was longer, CAT activity was completely lost even though some enzyme band occurred in the electrphoretic analysis. In addition, the degeneration of CAT due to UV-B irradiation was inhibited to some extent by using RGP lens with a UV-B blocking of 63.7%, however, it was not completely inhibited. Conclusions: From these results, it was revealed that the structural denaturation of antioxidative enzymes was not perfectly correlated with the reduction in enzyme activity according to the type of enzyme. It is recommended to minimize the exposure time to UV when wearing contact lens, or wear the contact lenses having UV blocking rate of the FDA Class I blocker or the sunglasses having equivalent UV-blocking rate for reducing the damage of antioxidative enzymes induced by UV.

• Korean Journal of Cognitive Science
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• v.6 no.1
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• pp.47-71
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• 1995

A psychological disturbance caused by letters in double image was termed as'letter sickness'.The effects of stimulus exposure time and letter familiarity on the letter sickness were measured to test a hypothesis that disturbances in eye movement and recognition stages is the cause of letter sickness.Letter sickness incteased significantly as stimulus exposure time lengthened from 50ms,100ms,to 3000ms.It was also significantly higher with familiar Hangul letters as compared with less familiar foreign letters and meaningless words as compared with meaningful words,respectively.These experimental findings imply that letter sickness is caused by the failure of adjusting eye movements to dismiss the double images.that the more familiar the letters.the more strongly the letter-identification process is commotted,resulting in the increased effect of disturbance from double image.and that the disturbance effect of double image is amplified when it is hard to extract the meaning from familiar letters.An experiment where subjects were made to learn Braille-like symbols consisting of 6 dots to test the hypothesis that the stronger the tendency to process the meaning of a symbol,the stronger becomes letter sickness due to double image,also showed that letter sickness significantly increased as a function of learning.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.7 no.6
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• pp.1202-1209
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• 2003

With explosive growth of Internet users, the market share of electronic commerce becomes wider. Therefore the Internet is standing in the spotlight of a new medium of advertisement, and several Internet advertising methods have been implemented. However the banner advertising that is the typical internet advertising method is showing low click rate because of user's unconcern. Accordingly we propose a new Internet advertising method that makes expose advertising content on the background of web browser when user puts mouse pointer over a specified text. Internet users are willing to click a interesting text, just at that moment the advertising content is appeared on the background of web browser. Therefore we could expect high effectiveness of advertising and moreover after clicking the text, the advertising content is shown continually on the web browser. The proposed method, unlike banner advertising, various shapes of image can be applied and makes use of whole background of web page.

• Cartoon and Animation Studies
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• s.41
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• pp.307-336
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• 2015

Virtual reality technology is one of the important technologies that will affect our life in many ways. This novel technology will draw new paradigm into the medical field due to its advantages in physical safety and environment that are fully controlled. Phobia treatment using VR technology has been implemented and its feasibility has been proved through a number of researches in many institutions. This study has observed the current progress of its technology environment and the trend of research. Also, This study has analyzed the results from domestic and international data. Analysis shows that other countries are ahead of korea in all aspects of the phobia treatment using virtual reality method. Although the authors limited the kinds of journals, the amount of quantity in international researches are two times more than domestics. Also, The researchers in other countries concentrate on the multi-modal studies. To use virtual reality in the phobia treatment, we need to understand the needs of the society members and the government has responsibility to support what the researchers need.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.12
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• pp.765-773
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• 2018

The purpose of this study was to investigate the effect of Healing Beat on autonomic balance, heart rate, and anxiety in healthy adults exposed to stressors. Data were collected from 64 healthy volunteers who volunteered after responded to a recruitment announcement at D City University and analyzed using descriptive statistics, the X2-test, the t-test, and repeated measures of ANOVA. Results showed that both experimental and control general characteristics and variables were homogeneous. Significant intergroup differences were obtained for autonomic balance (F = 6.151, p <.001), heart rate (F = 5.455, p <.001), and anxiety (t = -7.633, p <.001). These results indicate Healing Beat is effective at relieving anxiety in stressful situations, and that Healing Beat can be used to relieve stress in many clinical situations or daily life when individuals are exposed to various stressors.

• Journal of the Korea Convergence Society
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• v.13 no.4
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• pp.373-381
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• 2022

The Fukushima nuclear power plant water spill caused by the Great East Japan Earthquake in March 2011 raised fears about radiation exposure through consumption of radioactively contaminated seafood. The Korean government banned importing agricultural and fishery products from eight prefectures near Fukushima, but the related news were continuously reported partly due to the WTO dispute with Japan, which seems to have aggravated consumers' anxiety about seafood. In this study, data on daily purchases of products for three years (2018-2020) were collected and the effect of Japanese radiation-related news on domestic consumers' purchases of seafood was estimated using a polynomial lag distributed model. As a result of the analysis, it was found that radiation-related news had a statistically significant negative effect on the purchase of seafood on the 5th and 6th days after exposure to consumers through the media. It captures the carryover effect in which consumers' perceptions are reflected in the purchase of seafood after exposure to related news.

• Journal of the Korean Society of Radiology
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• v.10 no.5
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• pp.321-325
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• 2016

Dose creep is one of clinical errors that arises from the tester's inexperience or carelessness, and according to Task Group #116 of American Association of Physicists in Medicine, its continued occurrence is being reported in the digital method. At this point, the demand for an automatic exposure control device that minimizes the dose creep phenomenon and can improve reproducibility is increasing. In this study is to consider the automatic exposure control device sensor that can is not only easy to produce, but also reduce the dose creep phenomenon by conducting a research on high-efficient semiconductor sensor. As a result, the Intrinsic-type and PIN-type sensors have excellent optical property compared to Ref sensor, would have less shading effect, and have relatively low sensitivity, but would provide accurate feedback signals to automatic exposure control device with its consistent tendency according to exposure condition changes.

• Food Science and Preservation
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• v.23 no.7
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• pp.960-966
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• 2016

This study was conducted to explore the potential for use of atmospheric pressure dielectric barrier discharge plasma (atmospheric pressure DBD plasma) as a non-thermal sterilization technology for microorganisms in dried red pepper. The effects of key parameters such as power, exposure time and distance on the sterilization efficiency and the quality of red dried pepper by the atmospheric pressure DBD plasma treatment were investigated. The results revealed that the plasma treatment was very effective for sterilization of Staphylococcus aureus, with 15 min of treatment at 1.0 kW and 20 mm sterilizing 82.6% of the S. aureus. Increasing the power or exposure time and decreasing the exposure distance led to improved sterilization efficiency. The atmospheric pressure DBD plasma treatment showed no effect on the ASTA (American spice trade association) value or hardness of dried red pepper. Furthermore, no effects of atmospheric pressure DBD plasma treatment were observed on the sensory properties of dried red pepper. To assess the storage stability, the dried red pepper was treated with atmospheric pressure DBD plasma (1.5 kW power, 15 min exposure time and 10 mm exposure distance), then stored for 12 weeks at $25^{\circ}C$. Consequently, the ASTA value, hardness and capsaicin concentration of dried red pepper were maintained.

• 한국노년학
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• v.36 no.4
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• pp.1109-1124
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• 2016

We examined the effect of stereotype threat (STT) on spatial working memory and facial emotion recognition in Korean elderly. In addition, we investigated the role of expected moderator such as self-perception of aging. Seventeen seniors (male=7) received basic cognitive tests including K-WMS-IV, MMSE and answered self-report questionnaires including self-perception of aging, anxiety of aging, attitude toward aging and age identity on the first visit. On the second visit, they were exposed to negative stereotype by reading a script detailing cognitive decline related to aging while a control group was exposed to a neutral content. Following the exposure, they were tested on a spatial-working memory task (Corsi-block tapping task) and emotion recognition task (facial expression identification task). The results showed that the seniors exposed to STT showed significantly lower performance on emotion recognition task (p < .05) (i.e., especially on the more difficult facial stimuli). In addition, there was a significant interaction between STT and self-perception of aging (p< .05), indicating that those who have positive self-perception of aging did not show impairment in emotion recognition task and difficult spatial working memory task under STT. On the other hand, those with negative self-perception of aging showed impaired performance under STT. Taken together, the current study suggests that being exposed to STT could negatively influence cognitive and emotional functioning of elderly. Interestingly, having a positive self-perception of aging could protect the underperformance caused by STT.

• The Journal of Korean Obstetrics and Gynecology
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• v.18 no.4
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• pp.1-9
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• 2005

Purpose : 이 연구는 SKBR3 인간 유방암 세포주에 대한 Euonymus alatus (Thunb.) Sieb 추출물 (CWE) 의 증식억제, 항산화 작용 및 세포사 유발 효과를 검토하기 위해 이루어 졌다. Methods : SKBR3 세포주는 48시간 동안 다양한 농도 ($0-40\;{\mu}g/ml$)의 CWE를 첨가하면서 배양되었고, 세포의 생존 비율은 MTT 배양을 통해서 평가하였다. 또한 CWE의 증식억제 효과는 유방암 세포주의 세포사와 관련되어 있음을 형태학적인 변화와 올리고뉴클레오솜 DNA 분절을 통해 확인하였다. Results : CWE의 50%에서 효과를 나타내게 하는 약물농도인 $ED_{50}$ (effective dose 50%)은 $9.3+2.2{\mu}g/ml$이며, 약물의 농도에 의존하여 세포의 증식을 억제시켰다. 아울러, 다양한 농도와 배양시간에서 CWE가 ROS 생산을 억제하는 것을 밝힐 수 있었다. 따라서 이러한 작용과 항암예방효과는 농도와 노출 시간에 의존하였다. Conclusion : 이러한 관찰을 통해 Euonymus alatus (Thunb.) Sieb의 열수 추출물은 SKBR3 인간 유방암 세포주에 대해 강한 증식억제 효과와 강력한 항산화효과 및 세포사의 유발 효과를 가지는 것으로 인식할 수 있다.