• The Journal of the Korea Contents Association
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• v.9 no.7
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• pp.268-275
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• 2009

Today, in order to cope with the changing security environments and the citizen demand actively and efficiently, the Korean police is attempting a great change inside and outside such as the practical application of decentralized police system. Police's corruption is serious in various statistical data that present from lower part that is show. compares to continuous upright improvement effort and evaluation of the inside of the police system. the citizens recognition against it is evaluated lowly. The difference of recognition on police potential integrity between members of the police organization, the citizen and the external agency points the insufficiency of police improvement, deficiency of effective system and policy, organization culture as causes.

• Proceedings of KOSOMES biannual meeting
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• 2004.05b
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• pp.73-79
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• 2004

When large-scale oil spill happens, it will put the fatal impact on the ecosystem, ultimately harm human being seriously. Accordingly every coastal country invests to improve response technologies, of which oil removal by use of bioremediation agent is taken to be secondary or alternative cleanup method in a specific spilled area In this regards, the author attempts to find out the efficiency and effectiveness of bioremediation agent to oil slick by laboratory experiment as well as the possibility of bioremediation application to future spill accident and gets the some results. In this study, the effectiveness and efficiency of bioremediation agent to oil slick is examined by short-term laboratory test and it is found that bioremediation agent am degrade oils effectively. however, considering the environment c! spill site is quite different from that of lab, the author will carry on the on-scene test of bioremediation for longer period to look into the possibility of biorediation agent as one of oil spill response methods.

• Proceedings of the Korea Contents Association Conference
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• 2007.11a
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• pp.315-318
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• 2007

Today, in order to cope with the changing security enviornments and the citizen demand actively and efficiently, the Korean police is attemting a great change inside and outside such as the practical application of decentralized police system and investigation structure regulation. Compares to continuous upright improvement effoer and evaluation of the inside of the police system, the citizens recognition against it is evaluated lowly. The difference of recognition on police potential integrity between members of the police organization, the citizen and the external agency points the insufficiency of police improvement, deficiency of effetive system and policy, organization culture as causes.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.34 no.4
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• pp.303-309
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• 2008

Deficiency of collagen regeneration, denaturalization of elastic fibers, and promotion of reactive oxygen species formation are important factors for deterioration of skin function. They induce wrinckle formation and decrease skin elasticity. Vitamin C and its derivatives have been used as cosmetic ingredients for anti-aging effects but their chemical instability has been a major problem. In an attempt to develop a novel anti-aging agent with a improved stability and bioactivity, the anti-wrinkle effect of 3-O-cetyl-L-ascorbic acid (VCCE), a new vitamin C derivative, was investigated in this study. VCCE increased procollagen type-1 synthesis in a dose-dependent manner (149% at 0.002%) in cultured fiboroblasts. Its potent anti-wrinkle effect was confirmed in vivo by analyzing human skin replica by a visiometer and the PRIMOS system. It did not cause any irritation in human patch test. Taken together, our findings suggest that the VCCE has potential benefits applicable to cosmetics for anti-wrinkle effects.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.45 no.7
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• pp.558-565
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• 2017

Recently, there has been a tendency to lead the private sector in the launch vehicle market, and as the market has become saturated, efforts are being made to reduce the launch cost. Advanced countries in space development have promoted manned long-range space exploration plans. As oxygen/methane is more efficient, lower cost, and eco-friendly than typical propellants, and can be produced locally on an alien planet, it is the most suitable next-generation propellant to meet this trend. Now methane engine development is accelerating due to changes in international conditions and corporate environment. It is also expected to develop a methane engine in order to survive in this global trend and to keep up with the launch vehicle market in the future.

• The Journal of Society for e-Business Studies
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• v.23 no.2
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• pp.67-81
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• 2018

Technology commercialization is a reward process for companies' various trials and investment to develop technologies, which can be regarded as a way to figure out company's business performance. To successfully attain companies' purpose via technology commercialization, a variety of knowledge which triggers and completes business activities are needed. This paper suggests a methodology to analyze problems and solutions around the technology commercialization process in terms of knowledge distribution status, especially focused on Korean SMC cases. The knowledge map of this paper is constructed from the knowledge networks and identifies problems and solutions of the target process. A case study for applying proposed concepts to SMC's cases is also performed by checking knowledge distribution status and extracting practical implications. This paper's ideas can be regarded as one of references for SMCs to prepare technology commercialization with guaranteeing facilitated knowledge distribution and utilization.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.37 no.1
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• pp.91-96
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• 2011

Deficiency of collagen regeneration, denaturalization of fibers, increased melanin synthesis and reactive oxygen species are important factors inducing deterioration of healthy skin function. They induce freckles and decrease in skin elasticity. Vitamin C, vitamin A and their derivatives have been used as cosmetic ingredients for improvement of these problems but they have various problems. We have been developing the various derivatives of these ingredients. In this study, we investigated whitening effect of 3-o-cetyl-L-ascorbic acid (VCCE), a new vitamin C derivative. The VCCE inhibited melanogenesis in a dose dependent manner(44 % at $20\;{\mu}g/mL $) and tyrosinase expression. For 8 weeks, we also investigated skin brightening effect of VCCE on pigmented spots in UV-irradiated human skin. In results, VCCE showed a statistically significant skin whitening effect by mechanical and visual evaluation. Taken together, our findings suggest that the VCCE has potential benefits as an active ingredient for whitening cosmetics.

• KDI Journal of Economic Policy
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• v.18 no.2
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• pp.3-61
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• 1996

80년대초 이후 기술혁신의 가속으로 중소기업에서도 기술변화에 대한 적응이 경쟁력의 유지를 위한 핵심과제가 되면서, OECD 국가는 중소기업에 대한 과학기술정보(科學技術情報)의 이전(移轉)을 촉진하는 정부지원을 확충하였다. 경제성과의 개선을 위해서는 기술혁신만이 아니라 기술혁신의 성과를 확산시키는 것도 중요하다는 인식으로 중소기업의 경쟁력향상에 기여하는 과학기술정보의 공급확대를 위하여 연구개발사업(硏究開發事業)에 대한 지원을 강화하는 동시에 중소기업에 대한 과학기술정보의 이전을 촉진하기 위하여 과학기술정보의 공급원(供給源)(대학, 시험연구기관 등)과 중소기업을 연결하는 다양한 중개(仲介)(촉매(觸媒))기관(機關)의 설립 운영을 지원하고 있다. 연구개발과 과학기술정보이전에 관한 과학기술공급원과 중소기업간의 인식의 차이를 해소하기 위하여 정보교환(情報交換)과 인적교류(人的交流)를 확대하고 과학기술공급원이 제공하는 지식을 중소기업이 이용하기 쉬운 기술로 변환하기도 한다. 이러한 기능을 중개기관이 효과적으로 수행하기 위해서는 중소기업 사업자와 신뢰관계(信賴關係)를 구축하는 것이 긴요하며, 기술변화를 인지 수용하도록 유도하는 초기단계에서는 중소기업의 네트워크를 통하여 접근하는 것이 효과적이다. 이러한 기술확산과정(技術擴散過程)의 특성으로 인하여 지역혁신체제(地域革新體制)의 구축과 기술혁신정책(技術革新政策)의 지역화(地域化)가 강조되고 있다. 최근에 통상산업부와 과학기술처도 기술혁신정책의 지역화를 시도하고 있다. 연구기반과 산업기반을 고려하여 지역별로 다양한 유형의 산학연 공동연구기반이 구축될 계획이다. 기술혁신정책의 지역화는 시도단계에 불과하며 효율적인 지역혁신체제를 구축하기 위한 여건도 불리하다. 선진국에 비하여 대학과 연구기관의 연구자원(硏究資源)에서도 현격한 차이가 있으나, 네트워크의 혁신성을 좌우하는 지식집약형 중소기업의 비중과 중소기업기술개발의 혁신성에서도 선진국에 비하여 절대열위에 있다. 이러한 불리한 여건을 극복하기 위하여 중소기업의 혁신현장에 밀착된 지역의 전문가집단이 지역경제의 비전과 지역산업의 특수성을 고려하여 지역연구개발사업(地域硏究開發事業)을 전략적으로 기획하고 효율적으로 추진하며, 기획 추진과정에 참여하는 지역대학 지역시험연구기관 지역산업단체 등이 구성하는 지역사회(地域社會)의 협의체(協議體)가 정보공유(情報共有)와 공동학습(共同學習)을 통하여 지역혁신체제의 형성을 주도하고 경쟁과 협력의 조화를 통하여 기술혁신을 가속시키는 지역사회(地域社會)의 규범(規範)과 문화(文化)가 정착되도록 노력하며 중앙정부는 지역연구개발사업에 대한 지원에서 투명하고 합리적인 평가기준을 제시하고 지역산업의 혁신성과에 의하여 지원을 차등화(差等化)하는 경쟁원리를 도입하여 지역사회의 합리적 의사결정을 유도해야 한다.

• Korean Journal of Animal Reproduction
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• v.21 no.1
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• pp.1-7
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• 1997

Recently the production of transgenic animals to express foreign proteins in mammary glands has been a routine procedure. However, it still takes a considerable time and effort, and is faced with various technical challenges until the protein of interest is successfully made. Thus, a development of an a vitro model for mamm a ary-specific gene expression for recombinant genes was carried out in this study. To this end, bovine $\alpha$$_S1$ casein cDNA was inserted at the multiple cloning site of pMSG vector under the control of MMTV promoter. MCF$_7$ cells were tran sfected with pMSG $\alpha$$_S1$ CN by CaP0$_4$ precipitation. Transfectants were selected in HAT medium and induced with dexamethasone. The cells were analyzed with chicken anti-casein and FITC-labeled rabbit anti-chicken antibodies. The results showed that dexamethasone induced 30-40 fold increase in the MMTV- $\alpha$$_S1$ casein e expression. Therefore MCF$_7$ cells, which have multiple steroid receptors, along with pMSG vector can be used as an in vitro model for the study of mammary-specific gene expression.

• Journal of Digital Convergence
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• v.14 no.3
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• pp.35-43
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• 2016

Internal and external environment changes surrounding our society are pressing our government to solve a lot of difficult problems. These problems are more likely to be solved by a number of ministries and agencies, rather than a single ministry or agency. Thus collaboration is a necessary strategy to increase government's problem-solving skills. This study examines determinants of successful collaboration by analysing cases of local governments that solved uneasy problems covering many ministries after persistent efforts which have been controversial issues in our society. First, theoretical approach for collaboration and its matrix is examined. Second, interviews of government officers are analyzed to study collaboration cases. Finally, Strategic points of view are discussed to promote collaboration within government sectors. The results show that common goal sharing, incentives and supporting systems play important roles in inducing collaboration.