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Radiprotective Effects of S-2-($\omega$-aminoalkylamino) ethyl Derivatives and Their Drug Toxicities (S-2-($\omega$-aminoalkylamino) ethyl 유도체(誘導體)들의 방사선장해방호효과(放射線障害防護效果)와 독성(毒性))

  • Kim, You-Sun;Kim, Suc-Won
    • Journal of Radiation Protection and Research
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    • v.8 no.2
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    • pp.1-7
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    • 1983
  • S-2-($\omega-aminoalkylamino) ethyl dihydrogen phosphorothioates and S-2-($\omega$-aminoalkylamino) ethyl isothiuronium bromides were prepared from easily available starting compounds via convenient synthetic processes. The isothiuronium derivatives showed extreme drug toxicities as compared to that of AET, which seemed to be due to an intramolecular rearrangement of these compounds. The propyl derivative of the phosphorothioate could show better radioprotective effect than those of AET and WR-638, whereas the ethyl derivative of the equivalent drug dose revealed far less protective effect. The correlation between radioprotective effects, drug toxicities, and chemical structures were discussed through infrared spectroscopy.

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Stress and Displacement Fields of a Propagating Mode III Crack in Orthotropic Piezoelectric Materials (직교이방성 압전재료에서 전파 하는 모드 III 균열의 응력장과 변위장)

  • Lee, Kwang-Ho
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.34 no.6
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    • pp.701-708
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    • 2010
  • The stress and displacement fields of a permeable propagating crack in orthotropic piezoelectric materials under anti-plane shear mechanical load and in-plane electric load are analyzed. The equations of motion for the propagating crack in piezoelectric materials are developed and the solution on the stress and the displacement fields through an asymptotic analysis was obtained. The influences of the piezoelectric constant and of the dielectric permittivity on the stress and displacement fields at the crack tip are explicitly clarified. Using the stress and displacement fields obtained in this study, the characteristics of stress and displacement at a propagating crack tip in piezoelectric materials are discussed.

Medial Longitudinal Fasciculus on MRI in a Patient with Internuclear Ophthalmoparesis: A Case Report (신경핵사이 눈근육마비환자에서 자기공명영상에서의 내측세로다발: 증례 보고)

  • Kim, Sung Min;Kim, Ho Kyun;Lee, Hui Joong
    • Investigative Magnetic Resonance Imaging
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    • v.18 no.2
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    • pp.167-170
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    • 2014
  • The medial longitudinal fasciculus (MLF) is myelinated composite tract, lying near the midline, ventral to periaqueductal grey matter that plays a key role in coordinating eye movements. A lesion of the MLF results in an ipsilateral adduction deficit and a contralateral abducting nystagmus, referred to as an internuclear ophthalmoparesis. The blended tract with adjacent white matter in pons and midbrain is indistinguishable on brain imaging such as CT and MRI. Until now, to the best of our knowledge, MLF is not delineated on in vivo MRI. We present a case showing the whole connecting courses of MLF lesion on MRI in a patient with inflammatory demyelinating disorder.

Artificial Neural Network based Motion Classification Algorithm using Surface Electromyogram (표면 근전도를 이용한 Artificial Neural Network 기반의 동작 분류 알고리즘)

  • Jeong, E.C.;Kim, S.J.;Song, Y.R.;Lee, S.M.
    • Journal of rehabilitation welfare engineering & assistive technology
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    • v.6 no.1
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    • pp.67-73
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    • 2012
  • In this paper, Artificial Neural Network(ANN) based motion classification algorithm is proposed to classify wrist motions using surface electromyograms(sEMG). surface EMGs are obtained from two electrodes placed on the flexor carpi ulnaris muscle and extensor carpi ulnaris muscle of 26 subjects under no strain condition during wrist motions and used to recognize wrist motions such as up, down, left, right, and rest. Feature is extracted from obtained EMG signals in time domain for fast processing and used to classify wrist motions using ANN. DAMV, DASDV, MAV, and RMS were used as features and accuracies of motion classification based on ANN were 98.03% for DAMV, 97.97% for DASDV, 96.95% for MAV, 96.82% for RMS.

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Field Study for Location Estimation System of Dielectric breakdown in Gas Insulated Switchgear (GIS 절연파괴 위치 추정 시스템의 현장 적용 연구)

  • Min, Byoung-Woon;Lee, Jung-Bok;Kim, Jung Pyo;Kim, Jung-Han
    • Proceedings of the KIEE Conference
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    • 2015.07a
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    • pp.543-544
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    • 2015
  • GIS(Gas Insulated Switchgear:가스절연 개폐장치)는 절연성능이 뛰어난 $SF_6$가스로 절연되어 초고압 전력의 제어(차단,투입)를 담당하는 중요한 장치이다. GIS는 절연성능을 검증하기 위하여 현장 운전전에 공장검수시험(내전압시험)과 현장 가압 시험을 수행한다. 이 때 GIS의 조립/운반/설치의 오류로 인한 절연성능 저하로 절연파괴(내부아크)가 발생될 수 있다. 그러나 GIS는 $SF_6$가스로 밀폐되어 있어 절연파괴를 정확히 알 수 없을 뿐만 아니라 사고 위치를 확인하기 어렵다는 단점을 가지고 있다. 따라서 본 논문에서는 이런 문제를 해결하기 위하여 GIS 내부에서 발생되는 사고를 신속하게 탐지하고 위치를 정확하게 표정할 수 있도록 개발된 GIS 절연파괴 위치 추정 시스템의 현장 적용연구를 수행하였다. 이를 통해 GIS 절연파괴 위치 추정 시스템의 성능을 확인하였다.

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Treatment of Acromioclavicular Joint Injury (견봉 쇄골인대 손상의 치료)

  • Noh, Kyu-Cheol;Lee, Jae-Won;Yoo, Yon-Sik
    • Journal of the Korean Arthroscopy Society
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    • v.15 no.1
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    • pp.58-68
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    • 2011
  • Acromioclavicular (AC) joint dislocations are common injuries in active individuals secondary to direct force on the lateral aspect of the adducted shoulder. Complete disruption of the acromioclavicular and coracoclavicular (CC) ligaments may occur, depending on the magnitude of the insulting force. Most of these injuries are successfully treated without surgery. However, for the treatment of cases in which surgical management is warranted, there are more than 100 surgical techniques available without a gold standard technique. We review the anatomy of the acromioclavicular joint, the diagnosis of disorders of this joint, and the different treatment options in this article.

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Etcher용 상부전극의 Life Time 평가 방법 연구

  • No, Seung-Wan;Song, Je-Beom;Sin, Jae-Su;Gang, Sang-U;Kim, Jin-Tae;Sin, Yong-Hyeon;Yun, Ju-Yeong
    • Proceedings of the Korean Vacuum Society Conference
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    • 2010.08a
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    • pp.43-43
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    • 2010
  • 반도체 및 디스플레이의 진공부품은 알루미늄 모제에 전해연마법(electrolytic polishing), 양극산화피막법(anodizing), 플라즈마 용사법(plasma spray) 등을 사용하여 $Al_2O_3$ 피막을 성장시켜 사용되고 있다. 반도체 제조공정 중 30~40% 이상의 비중을 차지하는 식각(etching) 및 증착(deposition) 공정의 대부분 은 플라즈마에 의해 화학적, 물리적 침식이 발생하여 피막에 손상을 일으켜 피막이 깨지거나 박리되면서 다량의 particle을 생성함으로써 생산수율에도 문제를 야기 시킨다. 본 연구에서는 이러한 진공부품의 하나인 etcher용 상부전극을 양극산화피막법(Anodizing)으로 $Al_2O_3$ 피막을 성장시킨 샘플을 제작하여 플라즈마 처리에 따른 내전압, 식각율, 표면 미세구조의 변화를 관찰하였고 이를 종합적으로 고려하여 etcher용 상부전극의 Life Time 평가 방법을 연구하였다. 이러한 실험을 통해 플라즈마 처리 후 피막에 크랙이 발생되는 것을 확인할 수 있었고 피막의 손상으로 전기적 특성이 감소되는 것을 확인할 수 있었다. 또한 플라즈마 처리 중 ISPM 장비를 이용하여 플라즈마 공정에서 발생하는 오염입자를 실시간으로 측정할 수 있는 방법을 연구하였다. 이러한 결과를 이용하여 진공공정에서 사용되는 코팅부품이 플라즈마에 의한 손상정도를 정량화 하고 etcher용 상부전극의 Life Time 평가 방법을 개발하여 부품 양산업체의 진공장비용 코팅부품의 개발 신뢰성 향상이 가능할 것으로 기대된다.

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Flashover Voltage of 800kV Class Composite Hollow Insulator for $SF_6$ Gas Insulated Switchgear (GIS) (800kV $SF_6$ 가스절연 개폐장치용 (GIS) 복합절연애자 (Composite Hollow Insulator)의 표면오손시 내전압특성)

  • Lee, C.R.;Yoon, J.H.;Choi, B.H.;Yoon, C.Y.;Ko, K.S.;Ban, S.G.;Huh, J.C.
    • Proceedings of the KIEE Conference
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    • 2002.07c
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    • pp.1449-1451
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    • 2002
  • A developed 800kV class composite hollow insulator for $SF_6$ Gas Insulated Switchgear (GIS) was tested as to insulation with their surfaces contaminated. The wet power frequency withstand voltage of the silicone rubber housing was about 135kV at an equivalent salt deposite density of $5kg/m^2$, to sufficiently satisfy the required performance. According to IEC 60507, the salt fog withstand voltage was measured at 565kV, and the highest measured leakage current was below 0.2mA. Therefore, it was clarified that the composite hollow insulator has sufficient insulation performance even when it is contaminated on the surface.

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Effect of the Melting atmospheres for the $SnO_2-(1-x)P_2O_5-xR_2O_3$ Glass System (SnO-(1-x)$P_2O_5-xR_2O_3$ 계 유리에서 $R_2O_3$ 치환 및 용융분위기의 영향)

  • Lee, Young-Hun;Ji, Mi-Jung;Lee, Hong-Lim
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2005.11a
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    • pp.206-207
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    • 2005
  • Display 소재로서 유전체나 격벽재 실링재로 사용되고 있는 frit는 PbO를 주성분으로 갖는 유리가 사용되고 있다. PbO 성분이 함유된(50$\sim$85%) 구성소재는 최근 RoHS 나 WEEE 등의 환경규제 실행에 직면해 있으며, 대체재료의 개발을 위한 많은 연구가 진행되고 있다 PbO 성분을 대체할 성분으로는 $Bi_2O_3$ 계, BaO-ZnO 계, $P_2O_5$ 계 등의 성분이 주요성분으로 이루어져 있으며, PbO 성분을 함유한 유리의 저융점, 저유전율, 고 투과율, 내산성, 내전압, 팽창계수 matching 등의 특성들에 부합되는 재료를 개발하기 위해 많은 노력을 기울이고 있다. 본 연구에서는 SnO-$P_2O_5$ 계 유리 조성을 선택하여 $R_2O_3$의 치환 및 용융분위기의 조절에 따른 저융점 유리로서의 특성과 효과에 대하여 고찰하였다.

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Cepstral and spectral analysis of voices with adductor spasmodic dysphonia (내전형연축성 발성장애 음성에 대한 켑스트럼과 스펙트럼 분석)

  • Shim, Hee Jeong;Jung, Hun;Lee, Sue Ann;Choi, Byung Heun;Heo, Jeong Hwa;Ko, Do-Heung
    • Phonetics and Speech Sciences
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    • v.8 no.2
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    • pp.73-80
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    • 2016
  • The purpose of this study was to analyze perceptual and spectral/cepstral measurements in patients with adductor spasmodic dysphonia(ADSD). Sixty participants with gender and age matched individuals(30 ADSD and 30 controls) were recorded in reading a sentence and sustained the vowel /a/. Acoustic data were analyzed acoustically by measuring CPP, L/H ratio, mean CPP F0 and CSID, and auditory-perceptual ratings were measured using GRBAS. The main results can be summarized as below: (a) the CSID for the connected speech was significantly higher than for the sustained vowel (b) the G, R and S for the connected speech were significantly higher than for the sustained vowel (c) Spectral/cepstral parameters were significantly correlated with the perceptual parameters, and (d) the ROC analysis showed that the threshold of 13.491 for the CSID achieved a good classification for ADSD, with 86.7% sensitivity and 96.7% specificity. Spectral and cepstral analysis for the connected speech is especially meaningful on cases where perceptual analysis and clinical evaluation alone are insufficient.