• The monthly packaging world
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• s.81
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• pp.172-182
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• 2000

• The monthly packaging world
• /
• s.76
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• pp.174-182
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• 1999

• The Korean Journal of Pesticide Science
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• v.6 no.3
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• pp.135-156
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• 2002

내분비계 장애물질이 환경호르몬이란 용어로 우리들의 실생활에 사용되는 용기 등을 통해 여러 가지 영향을 미치고 있다. 수많은 화학물질들 중에서 환경호르몬은 어떠한 종류의 화학물질이며, 언제 알려지게 되었고, 어떻게 분류되었으며, 이러한 환경호르몬성을 갖는 물질들의 환경호르몬성은 어떠한 연구기법에 의해 검색되는지와 현재까지의 사용실태와 문제점 및 국내외 관련 동향 등을 고찰하여 보았다.

• Bulletin of Food Technology
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• v.20 no.4
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• pp.3-10
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• 2007

• Proceedings of the Korea Society of Environmental Toocicology Conference
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• 2000.12a
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• pp.61-61
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• 2000

• Proceedings of the Korean Society of Life Science Conference
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• 2003.10a
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• pp.54-54
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• 2003

• 한국생물공학회:학술대회논문집
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• 2000.04a
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• pp.117-120
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• 2000

For detecting toxicity of endocrine disruptors (EDs), rapid, sensitive, and simple methods are needed. Therefore, in this study, a new method in which the different toxic effect of EDs can be monitored using 4 different recombinant bacteria was designed and evaluated. It was found that the recombinant bacteria could monitor the toxic effect, not estrogenic effect, due to EDCs through the measurement of bioluminescence and cell growth rate, which were shown to depend upon a form of cellular toxicity, such as DNA damage, protein damage, oxidative damage, and membrane damage. In addition, it was found that the damage done by EDCs can be divided into several groups based upon the toxic mechanisms of the EDCs

• KSBB Journal
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• v.18 no.5
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• pp.424-428
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• 2003

In the present study, we have analyzed effects of the endocrine distruptors, such as bisphenol A, nonylphenol and pentachlorophenol, on cell proliferation in the human breast cancer cell line, MCF-7, and the human prostate cancer cell line, PC-3, with MTT method. A dose dependent analysis of the cell proliferation of MCF-7 cells after administration of bisphenol A, nonylphenol and pentachlorophenol revealed a significant induction of cell proliferation. Maximum induction of cell proliferation was observed at concentrations between 10$\^$-7/ and 10$\^$-6/ M. Whereas, these chemicals had little effect on proliferation of PC-3 cells. These results demonstrated that bisphenol A, nonylphenol and pentachlorophenol do not induce proliferation of PC-3 cells but exhibit a significant induction of MCF-7 cell proliferation, suggesting all these chemicals are a estrogen mimic.

• 한국상하수도협회지
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• s.1
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• pp.42-48
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• 2002

• The monthly packaging world
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• s.85
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• pp.177-181
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• 2000