• Title/Summary/Keyword: 내당능

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The effects of different intensity endurance and resistance exercise on diabetic-related blood profiles in impaired glucose tolerance mice (다른 운동 강도의 지구성 및 저항성 운동 중재가 내당능 장애 쥐들의 당뇨관련 혈액인자에 미치는 영향)

  • Park, Chan-Ho;Woo, Jin-Hee;Roh, Hee-Tae;Shin, Ki-Ok;Kim, Do-Yeon;Yoon, Byung-Kon
    • Journal of the Korean Applied Science and Technology
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    • v.37 no.3
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    • pp.571-581
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    • 2020
  • The purpose of this study was to investigate the effect of endurance and resistance exercise by using different intensity on diabetic-related blood profiles in impaired glucose tolerance mice. 54 C57BL/6 mice were divided into (1) Control group (CO, n=9), (2) impaired glucose tolerance group (IGT, n=9), (3) IGT + 50% of VO2max endurance exercise group (IGT50A, n=9), (4) IGT + 75% of VO2max endurance exercise group (IGT75A, n=9), (5) IGT +50% of 1RM resistance exercise group (IGT50R, n=9), 그리고 (6) IGT + 75% of 1RM resistance exercise group (IGT75R, n=9). Endurance exercise program was performed 40 min/day, 5 days a week for 8 weeks on treadmill. Resistance exercise program was consisted in ladder-climbing 8 set/day, 5 days a week for 8 weeks. After completed the exercise program, there was no different insulin level in the groups. The fasting glucose was significantly lower in CO than in other groups, and it was not different among the exercised groups. However, IGT75R was statistically lower than IGT. HOMA-IR was only different between CO and IGT. HbA1c was higher in IGT than in other groups. As compared with exercised groups, IGT 75A was lower than IGT50R. TC was lower in CO than in other groups, but there was no different in TG. Endurance exercise groups showed higher than CO and IGT in HDL-C level. LDL-C was lower in CO than other groups. In addition, IGT75A was lower than IGT and IGT50R in LDL-C level. In conclusion, 75% of 1RM resistance exercise had more positive effect on fasting glucose, and 75% of VO2max endurance exercise improved HbA1c and LDL-C level. In addition, endurance exercise had more effective in HDL-C improvement as compared with resistance exercise.

Diabetes Story I - 당뇨의 전단계 - 내당능장애와 공복혈당장애 -

  • 사단법인 한국당뇨협회
    • The Monthly Diabetes
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    • s.219
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    • pp.50-51
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    • 2008
  • 당뇨병환자가 10만명을 육박해 당뇨 대란이 예상되는 가운데, 당뇨병 예비자 또한 그 수가 만만치 않다. 당뇨병 예비자에는 생활습관이 불규칙하거나, 운동을 전혀 하지 않는 사람, 비만한 사람 등이 포함이 되는데, 당뇨병 전단계라 불리우는 내당능장애와 공복혈당장애 환자도 마찬가지이다. 당뇨병 전단계는 확실하게 당뇨병으로 진단을 받은 것은 아니지만 당뇨병으로 발전할 가능성이 충분한 상태로써 공복, 식후혈당이 이상이 있는 경우를 말한다. 이러한 환자도 당뇨병환자와 똑같은 치료법으로 관리를 해야 훗날 당뇨병으로 발전하거나, 그로 인한 합병증의 피해를 줄일 수 있다.

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Effects of Regular Walking Exercise on Health-Related Parameters in Persons with Chronic Diseases (규칙적인 걷기운동이 질환별 노인의 건강변인에 미치는 효과)

  • Lim, Hwe-Jin;Kim, Yu-Sik;Cho, Hyeong-Suk;Kim, Chang-Hee;Lim, Hee-Jung;Jeong, Hee-Seong;Im, Jee-Aee;Yoon, Byung-Kon;Paik, Il-Young;Suh, Sang-Hoon
    • Journal of Life Science
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    • v.19 no.12
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    • pp.1750-1757
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    • 2009
  • The purpose of this study was to investigate the effects of regular walking exercise on health-related parameters in the elderly with chronic diseases - apoplexy, overweight, impaired fasting glucose, and overweight + impaired fasting glucose. A total of 85 subjects, 27, 17, 21 and 20 in apoplexy (A), overweight (O), impaired fasting glucose (IFG), overweight + impaired fasting glucose group (O_IFG), respectively, completed a 12-week walking exercise. The health-related parameters were measured before and at the completion of the exercise program including anthropometric measurements, functional physical fitness levels, blood pressure, fasting glucose, blood lipid profiles and chronic inflammatory markers (CRPs). Significant improvements in body weight, BMI, %body fat, blood pressure, all blood lipid measurements and all measured physical fitness items were shown in A; those in %body fat, TC, HDL-C and LDL-C in O; those in body weight, BMI, %body fat, fasting glucose, TC, TG and HDL-C in IFG; and those in body weight, HDL-C and LDL-C in O_IFG (p<0.05). The results of the present study demonstrated that a 12-week walking exercise brought positive effects on body weight, bloody lipid profiles, fasting glucose and functional physical fitness levels in the elderly with chronic diseases. In conclusion, this study suggested that walking regularly is very effective in lowering the risks of developing chronic diseases.

Serum Ferritin as a Risk Factor in Type 2 Diabetes Mellitus (2형 당뇨병 발생위험인자로서의 혈청 Ferritin의 의의)

  • Kim, Jeong Hyeon;Kim, Ho Seong;Kim, Deok Hui
    • Clinical and Experimental Pediatrics
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    • v.48 no.11
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    • pp.1239-1243
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    • 2005
  • Purpose : Iron accumulation interferes with hepatic insulin extraction and affects insulin synthesis and secretion. The purpose of this study is to investigate the correlation between serum ferritin and type 2 diabetes mellitus. Methods : We compared the serum ferritin level among 18 patients in an impaired glucose tolerance (IGT) group, 36 in a type 1 diabetes group, eight in a type 2 diabetes group and 29 in a healthy control group. The correlation between serum ferritin levels and sex, body mass indices(BMI), blood pressure(BP), serum fasting sugar level and serum fasting insulin level were also analyzed. Results : The mean log ferritin were $1.33{\pm}0.32$(healthy control group), $1.63{\pm}0.19$(IGT group) and $1.90{\pm}0.30$(type 2 diabetes group). In the IGT group, log ferritin was higher than in the healthy control group(P=0.001). The log ferritin of the type 2 diabetes group was higher than that of the healthy control group(P=0.001). Comparing log ferritin to other factors, log ferritin had a significant positive correlation with body mass indices(P<0.001), systolic blood pressure(P=0.001), and fasting glucose(P=0.001), fasting insulin(P=0.002). Conclusion : Compared to the normal healthy group, serum ferritin concentrations were significantly higher in the IGT group and the type 2 diabetes group. The elevation of serum ferritin concentration may be a risk factor of type 2 diabetes mellitus.

Effects of Acute forest Walking Exercise on Blood Glucose of IGT, NIDDM in the Elderly (산림 걷기 운동이 내당능장애와 인슐린 비의존형 당뇨병 노인 환자의 혈당치에 미치는 효과)

  • Choi, Jong-Hwan;Shin, Won-Sop;Rho, Ki-Taek;Yeon, Poung-Sik
    • Journal of Korean Society of Forest Science
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    • v.99 no.1
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    • pp.47-51
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    • 2010
  • The purpose of this study was to analyze the effect of acute forest walking exercise on blood glucose of IGT (impaired glucose tolerance), NIDDM (non-insulin dependent diabetes mellitus) in the elderly. There were four groups (n=60): forest walking exercise with IGT group (n=15; $66.21{\pm}4.16$ yrs), forest walking exercise with NIDDM group (n=15; $64.85{\pm}3.23$ yrs), field walking exercise with IGT group (n=15; $67.44{\pm}1.78$ yrs), field walking exercise with NIDDM group (n=15; $65.55{\pm}8.21$ yrs). They were tested on blood glucose levels at the beginning and at the end of each walking exercise. While the forest walking groups (interval + resistance exercise) worked for 40minutes with HRmax 50~60% level, the field walking groups (only aerobic exercise) worked for 40 minutes with HRmax 50~60% level. For data analysis, mean and standard deviation scores were calculated, and paired t-test and ANCOVA test were used. This study resulted in as follows. First, both walking groups showed the significant decrease of blood glucose in impaired glucose tolerance (IGT) after completing each exercise. Second, while the forest walking group showed the significant decrease of blood glucose in insulin dependent diabetes mellitus (NIDDM) after completing the forest exercise, the field walking group did not present any decrease of blood glucose in NIDDM after the field walking exercise. Therefore, the present findings suggest that the forest walking exercise as an interval and resistance exercise may be more effective to decrease blood glucose for IGT and NIDDM peoples in comparison to the field walking exercise as an aerobic exercise.