• Title/Summary/Keyword: 김 열

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Characterization of Antidiabetic Compounds from Extract of Torreya nucifera (비자나무 추출물의 항당뇨 활성물질의 특성 연구)

  • Kim, Ji Won;Kim, Dong-Seob;Lee, Hwasin;Park, Bobae;Yu, Sun-Nyoung;Hwang, You-Lim;Kim, Sang Hun;Ahn, Soon-Cheol
    • Journal of Life Science
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    • v.32 no.1
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    • pp.1-10
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    • 2022
  • Natural products have gained increasing attention due to their advantage of long-term safety and low toxicity for a very long time. Torreya nucifera is widespread in southern Korea and Jeju Island and its seeds are commonly used as edible food. Oriental ingredients have often been reported for their insecticidal, antioxidant and antibacterial properties, but there have not yet been any studies on their antidiabetic effect. In this study, we investigated several biological activities of T. nucifera pericarp (TNP) and seeds (TNS) extracts and proceeded to characterize the antidiabetic compounds of TNS. The initial results suggested that TNS extract at 15 and 10 ㎍/ml concentration has inhibitory effects on α-glucosidase and protein tyrosine phosphatase 1B, that is 14.5 and 4.35 times higher than TNP, respectively. Thus, the stronger antidiabetic TNS was selected for the subsequent experiments to characterize its active compounds. Ultrafiltration was used to determine the apparent molecular weight of the active compounds, showing 300 kDa or more. Finally the mixture was then partially purified using Diaion HP-20 column chromatography by eluting with 50~100% methanol. Therefore we concluded that the active compounds of TNS have potential as therapeutic agents in functional food or supplemental treatment to improve diabetic diseases.

Annual Variation on Observation and Activity Pattern of Korean Chipmunk (Tamias sibiricus) in the Seoraksan and Jirisan National Parks, South Korea (설악산과 지리산 국립공원에 서식하는 다람쥐의 연중 관찰 양상과 행동 패턴)

  • Eom, Tae-Kyung;Lee, Jae-Kang;Lee, Dong-Ho;Ko, Hyeongyu;Bae, Ho-Kyoung;Kim, Kyu-Jung;Hwang, Hyun-Su;Park, Go Eun;Choi, Won-Il;Lim, Jong-Hwan;Park, Chan-Ryul;Rhim, Shin-Jae
    • Korean Journal of Environment and Ecology
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    • v.36 no.4
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    • pp.361-367
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    • 2022
  • This study was conducted to identify annual variation of observation and activity pattern of Korean chipmunk (Tamias sibiricus) using camera traps in the Seoraksan and Jirisan National Parks, South Korea from May 2019 to May 2021. The annual variation was identified based on the observed frequency through weekly observations. Daily activity patterns of the species were also analyzed by season. The daily activity pattern of chipmunk appeared to be constantly diurnal across the years regardless of habitat or season. The Korean chipmunks living in the two different regions were observed in different time periods throughout the year. While the chipmunks inhabiting the Seoraksan were observed from 18th to 45th week, the chipmunks inhabiting the Jirisan National Park were observed from 7th to 48th week. This may be influenced by the hibernation period of chipmunks in the two different regions. In both regions, chipmunks were most frequently observed in autumn. It is considered that seasonal variation on population dynamic and activity patterns of chipmunks were reflected in the observation frequency. Although the observation frequency of camera trap is an indirect indicator and thus having a limitation that it cannot distinguish the population density and amount of activity for the target species, camera trapping is still an effective survey technique for monitoring mammals due to its high accessibility and easy use.

Riparian Vegetation Monitoring and Health Assessment by Pilot Opening of Nakdonggang River Estuary (낙동강하구 시범개방에 따른 수변식생 모니터링 및 건강성 평가)

  • Choi, Hyun-Gu;Kim, Hwa-Young;Lee, Jun-Yeol;Sohn, Byeong-Yong;Lee, Ji-Young
    • Korean Journal of Environment and Ecology
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    • v.36 no.5
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    • pp.445-459
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    • 2022
  • In this study, we investigated current vegetation and assessed the health of vegetation through the KERVI (Korea Estuary Riparian Vegetation Index) to monitor vegetation changes near estuaries due to the opening of the Nakdong River estuary. As the first investigation of the long-term monitoring, six areas near the Nakdong River estuary were surveyed twice in July and October 2021, and vegetation monitoring and a survey of species composition and distribution density of aquatic, riparian, and land plants were carried out. The survey identified 262 taxa, 82 families, 192 genera, 196 species, 3 subspecies, 26 varieties, and 1 form of vascular plants in the surveyed area. The results of the vegetation health assessment through KREVI showed that sites 1 and 6 were rated "Very good" in both surveys, sites 2 and 4 were rated "Very good" in the first survey and then "Good"in the second survey, and site 3 and 5 were rated one grade higher in the second survey than the first survey. The assessment showed that the health grades of most species in the survey area were generally high. Most of the potential natural vegetation after the opening of estuary gates to create a brackish water area is expected to consist of reed (Phragmites communisTrin.) communities. The area of the willow (Salix koreensisAndersson) community adjacent to the water area may be somewhat narrower, but the community will be maintained. In the case of freshwater areas in inland areas with very low salinity, reeds (Phragmites communisTrin.) are expected to occupy most of them, and some communities such as amur silver-grass (Miscanthus sacchariflorusBenth.) and cattails (Typha orientalisC. Presl) are expected to be distributed. We suggest establishing measures such as estuary gate operation to create healthy brackish water regions through long-term monitoring.

Analysis of the effect of long-term water supply improvement by the installation of sand dams in water scarce areas (물부족 지역에서 샌드댐 설치에 의한 장기 물공급 개선 효과 분석)

  • Chung, Il-Moon;Lee, Jeongwoo;Lee, Jeong Eun;Kim, Il-Hwan
    • Journal of Korea Water Resources Association
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    • v.55 no.12
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    • pp.999-1009
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    • 2022
  • The Chuncheon Mullori area is an underprivileged area for water welfare that does not have a local water supply system. Here, water is supplied to the village by using a small-scale water supply facility that uses underground water and underground water as the source. To solve the problem of water shortage during drought and to prepare for the increasing water demand, a sand dam was installed near the valley river, and this facility has been operating since May 2022. In this study, in order to evaluate the reliability of water supply when a sand dam is assumed during a drought in the past, groundwater runoff simulation results using MODFLOW were used to generate inflow data from 2011 to 2020, an unmeasured period. After performing SWAT-K basin hydrologic modeling for the watershed upstream of the existing water intake source and the sand dam, the groundwater runoff was calculated, and the relative ratio of the monthly groundwater runoff for the previous 10 years to the monthly groundwater runoff in 2021 was obtained. By applying this ratio to the 2021 inflow time series data, historical inflow data from 2011 to 2020 were generated. As a result of analyzing the availability of water supply during extreme drought in the past for three cases of demand 20 m3/day, 50 m3/day, and 100 m3/day, it can be confirmed that the reliability of water supply increases with the installation of sand dams. In the case of 100 m3/day, it was analyzed that the reliability exceeded 90% only when the existing water intake source and the sand dam were operated in conjunction. All three operating conditions were evaluated to satisfy 50 m3/day or more of demand based on 95% reliability of water supply and 30 m3/day or more of demand based on 99% of reliability.

Forage and TDN Yield of Several Winter Crops at Different Clipping Date (사료용 맥류 품종의 예취 시기별 청예 및 건물수량과 영양가 비교)

  • Hwang, Jong-Jin;Sung, Byung-Ryeol;Youn, Kyu-Bok;Ahn, Wan-Sik;Lee, Jong-Ho;Chung, Kyu-Yong;Kim, Young-Sang
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.30 no.3
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    • pp.301-309
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    • 1985
  • This experiment was conducted to know a substantial body of information about the differences of the important forage characteristics; green fodder yield, dry matter yield, TDN%, TDN yield and so forth of the seven cultivars selected as the forage crops (Rye, Triticale, Wheat and Barley) depending on the specific times of cutting stage, on the Wheat and Barley Research Institute from October, 1983 to June, 1984, and the results summarized as follows. Green fodder yield & dry matter weight, when clipped at 20, 30 April and 10 May, of varieties Homil #2 showed the most yielding capacity, but when clipped at 20 May, Suweon#8 (triticale) showed the most green fodder yield whereas Homil #1 the most significant dry matter weight. Plant height, in the cases of Paldanghomil, Homil #1 & Homil #2, showed distinctly longer than that of Bunong, Suweon #8 & Suweon #9 and continued to grow even after the heading date. Dry matter ratio increased with time (Dry matter yield/green fodder yield x100). TDN % decreased but TDN yield increased with time but Homil #1, Homil #2 and Paldanghomil showed relatively the higher values. In the elements of nutrient of cell wall, Suweon #8 & Bungong among 7 cultivars have good quality. The reasonable clipping date of wheat &barley as green fodder crops are 10 May to 20 May, but if clipped before 10 May and 20 May, Homil #2 and Suweon #8 became the promising forage crops, respectively.

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Cone Characteristics and Seed Quality among Harvest Times in the Clonal Seed Orchard of Larix kaempferi (낙엽송 클론 채종원에서 구과 채취시기에 따른 구과특성 및 종자품질)

  • Ye-Ji Kim;Da-Eun Gu;Gyehong Cho;Heeyoon Choi;Yeongkon Woo;Chae-Bin Lee;Sungryul Ryu;Hye-Joon Joo;Kyu-Suk Kang
    • Journal of Korean Society of Forest Science
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    • v.112 no.3
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    • pp.352-362
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    • 2023
  • Harvest time is one of the most important determining factors of seed quality, especially for species that produce seeds over irregular and long-term periods, such as Larix kaempferi. A cone collection plan must be established to increase seed production efficiency and stable mass production. We investigated seed qualities such as seed efficiency, germination rate, and T50 (germination speed), with 7 or 8 cone collection times at a clonal seed orchard of L. kaempferi in Chungju between 2021 and 2022. A multivariate analysis was then performed for the collected data. In early August, decreases in the moisture contents and browning of cones were observed. These were followed by a decrease in germination rate, with a peak at the end of September, but no clear trend was observed. The later the cones were harvested, the better the seed vigor (T50). However, the seed yield and efficiency decreased owing to increases in seed scattering and the number of insect-damaged seeds. As a result, the optimal time of seed harvest for the seed orchard was in early August. To produce uniform seedlings, insect damage must be reduced through timely control and harvest cones in early September. This shows that the degree of browning and moisture content of cones can be used as indicators of the timing of cone collection in L. kaempferi seed orchards.

Dynamic Equilibrium Position Prediction Model for the Confluence Area of Nakdong River (낙동강 합류부 삼각주의 동적 평형 위치 예측 모델: 감천-낙동강 합류점 중심 분석 연구)

  • Minsik Kim;Haein Shin;Wook-Hyun Nahm;Wonsuck Kim
    • Economic and Environmental Geology
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    • v.56 no.4
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    • pp.435-445
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    • 2023
  • A delta is a depositional landform that is formed when sediment transported by a river is deposited in a relatively low-energy environment, such as a lake, sea, or a main channel. Among these, a delta formed at the confluence of rivers has a great importance in river management and research because it has a significant impact on the hydraulic and sedimentological characteristics of the river. Recently, the equilibrium state of the confluence area has been disrupted by large-scale dredging and construction of levees in the Nakdong River. However, due to the natural recovery of the river, the confluence area is returning to its pre-dredging natural state through ongoing sedimentation. The time-series data show that the confluence delta has been steadily growing since the dredging, but once it reaches a certain size, it repeats growth and retreat, and the overall size does not change significantly. In this study, we developed a model to explain the sedimentation-erosion processes in the confluence area based on the assumption that the confluence delta reaches a dynamic equilibrium. The model is based on two fundamental principles: sedimentation due to supply from the tributary and erosion due to the main channel. The erosion coefficient that represents the Nakdong River confluence areas, was obtained using data from the tributaries of the Nakdong River. Sensitivity analyses were conducted using the developed model to understand how the confluence delta responds to changes in the sediment and water discharges of the tributary and the main channel, respectively. We then used annual average discharge of the Nakdong River's tributaries to predict the dynamic equilibrium positions of the confluence deltas. Finally, we conducted a simulation experiment on the development of the Gamcheon-Nakdong River delta using recorded daily discharge. The results showed that even though it is a simple model, it accurately predicted the dynamic equilibrium positions of the confluence deltas in the Nakdong River, including the areas where the delta had not formed, and those where the delta had already formed and predicted the trend of the response of the Gamcheon-Nakdong River delta. However, the actual retreat in the Gamcheon-Nakdong River delta was not captured fully due to errors and limitations in the simplification process. The insights through this study provide basic information on the sediment supply of the Nakdong River through the confluence areas, which can be implemented as a basic model for river maintenance and management.

Feasibility Assessment on the Application of X-ray Computed Tomography on the Characterization of Bentonite under Hydration (벤토나이트 수화반응 특성화를 위한 X선 단층촬영 기술 적용성 평가)

  • Melvin B., Diaz;Gyung Won, Lee;Seohyeon, Yun;Kwang Yeom, Kim;Chang-soo, Lee;Minseop, Kim;Jin-Seop, Kim
    • Tunnel and Underground Space
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    • v.32 no.6
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    • pp.491-501
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    • 2022
  • Bentonite has been proposed as a buffer and backfill material for high-level radioactive waste repository. Under such repository environment conditions, bentonite is subjected to combined thermal, hydrological, mechanical, and chemical processes. This study evaluates the feasibility of applying X-ray CT technology on the characterization of bentonite under hydration conditions using a newly developed testing cell. The cylindrical cell is made of platic material, with a removable cap to place the sample, enabling to apply vertical pressure on the sample and to measure swelling pressure. The hydration test was carried out with a sample made of Gyeonju bentonite, with a dry density of 1.4 g/cm3, and a water content of 20%. The sample had a diameter of 27.5 mm and a height of 34 mm. During the test, water was injected at a constant pressure of 0.207 MPa, and lasted for 7 days. After one day of hydration, bentonite swelled and filled out the space inside the cell. Moreover, CT histograms showed how the hydration process induced an initial increase and later progressive decrease on the density of the sample. Detailed profiles of the mean CT value, CT standard deviation, and CT gradient provided more details on the hydration process of the sample and showed how the bottom and top regions exhibited a decrease on density while the middle region showed an increase, especially during the first two days of hydration. Later, the differences in CT values with respect to the initial state decreased, and were small at the end of testing. The formation and later reduction of cracks was also characterized through CT scanning.

A prediction study on the number of emergency patients with ASTHMA according to the concentration of air pollutants (대기오염물질 농도에 따른 천식 응급환자 수 예측 연구)

  • Han Joo Lee;Min Kyu Jee;Cheong Won Kim
    • Journal of Service Research and Studies
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    • v.13 no.1
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    • pp.63-75
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    • 2023
  • Due to the development of industry, interest in air pollutants has increased. Air pollutants have affected various fields such as environmental pollution and global warming. Among them, environmental diseases are one of the fields affected by air pollutants. Air pollutants can affect the human body's skin or respiratory tract due to their small molecular size. As a result, various studies on air pollutants and environmental diseases have been conducted. Asthma, part of an environmental disease, can be life-threatening if symptoms worsen and cause asthma attacks, and in the case of adult asthma, it is difficult to cure once it occurs. Factors that worsen asthma include particulate matter and air pollution. Asthma is an increasing prevalence worldwide. In this paper, we study how air pollutants correlate with the number of emergency room admissions in asthma patients and predict the number of future asthma emergency patients using highly correlated air pollutants. Air pollutants used concentrations of five pollutants: sulfur dioxide(SO2), carbon monoxide(CO), ozone(O3), nitrogen dioxide(NO2), and fine dust(PM10), and environmental diseases used data on the number of hospitalizations of asthma patients in the emergency room. Data on the number of emergency patients of air pollutants and asthma were used for a total of 5 years from January 1, 2013 to December 31, 2017. The model made predictions using two models, Informer and LTSF-Linear, and performance indicators of MAE, MAPE, and RMSE were used to measure the performance of the model. The results were compared by making predictions for both cases including and not including the number of emergency patients. This paper presents air pollutants that improve the model's performance in predicting the number of asthma emergency patients using Informer and LTSF-Linear models.

Evaluation of the LG AdvansureTM Malaria P.f./P.v. real-time QPCR for the Diagnosis of Malaria (LG AdvansureTM Malaria P.f./P.v. real-time QPCR의 말라리아 진단 유용성)

  • Lee, Hye Jin;Kim, Ha Nui;Yoo, Byong Joon;Kim, Jang Su;Kim, Myong Han;Lim, Chae Seung;Lee, Kap No
    • Laboratory Medicine Online
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    • v.1 no.2
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    • pp.100-104
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    • 2011
  • Background: Malaria is a problematic disease in Korea, and microscopic examination of Giemsa-stained blood smear has been used as the gold standard for its diagnosis. However, this technique is time-consuming and has low sensitivity in samples with low numbers of malarial parasites (<20 parasites/μL). Here, we evaluated the performance characteristics of the LG AdvansureTM Malaria P.f./P.v. real-time QPCR (LG life sciences, Korea). Methods: Blood samples from 173 persons who visited Korea University Ansan Hospital were evaluated. QPCR was performed in 73 malaria patients and 100 healthy subjects by using the LG Advansure Malaria P.f./P.v. real-time QPCRR kit, and the results were compared with those of microscopy. The detection limit of this kit was determined by serial dilution of Plasmodium-infected blood with normal blood (blood not infected with Plasmodium). Results: Among the 73 patients that were microscopically confirmed to have malaria (Plasmodium vivax infection, N=70, P. falciparum infection, N=3), 69 patients were diagnosed with P. vivax infection and 3 were diagnosed with P. falciparum infection by LG AdvansureTM Malaria P.f./P.v. realtime QPCR. Both the tests indicated absence of infection in the 100 healthy subjects. The detection limit of LG AdvansureTM Malaria P.f./P.v. real-time QPCR was 0.1 parasite/μL. Conclusions: LG AdvansureTM Malaria P.f./P.v. real-time QPCRis a very sensitive and specific technique and can be used as a confirmatory test for malaria.