• Radiation Oncology Journal
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• v.27 no.4
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• pp.189-193
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• 2009

Purpose: To report on the changes in the patterns of care and survival over time for esthesioneuroblastoma. Materials and Methods: We retrospectively analyzed 42 previously untreated and histologically confirmed esthesioneuroblastoma patients seen between March 1989 and June 2007. According to Kadish's classification, 3 patients (7%) were stage A, 6 (14%) at stage B, and 33 (79%) at stage C. Of the 33 Kadish C patients, 19 and 14 patients were treated from 1989 through 2000 and from 2001 through 2007, respectively. Treatment included surgical resection, radiotherapy, chemotherapy, or a combination of these methods. Chemotherapy was administered to 8 of 19 patients (42%) seen from 1989 through 2000, whereas all of the 14 patients seen from 2001 through 2007 received chemotherapy (p<0.001). No patient was treated by three-dimensional conformal radiotherapy (3D-CRT) from 1989 through 2000, however 8 of 14 patients (67%) seen from 2001 through 2007 underwent 3D-CRT (p<0.001). The median follow-up time for surviving patients was 6.5 years (range, 2.2~15.8 years). Results: The 5-year overall survival (OS) and progression-free survival (PFS) rates for the entire cohort were 53% and 39%, respectively. The 5-year OS was 100% for Kadish stages A or B and 39% for stage C (p=0.007). For patients with stage C disease who were treated from 1989 to 2000 and from 2001 to 2007, the 5-year OS rate was 26% and 59% (p=0.029), respectively and the corresponding 5-year PFS rate was 16% and 46% (p=0.001), respectively. Intraorbital extension and treatment era (1989~2000 vs. 2001~2007) were found as independent factors for OS and PFS in a multivariate analyses. Conclusion: The results of this study suggest that treatment era, which features a distinction in treatment modality and technique with the introduction of 3D-CRT, may be the cause of improved OS and PFS in Kadish stage C patients. To achieve better outcomes for patients with Kadish stage C, combined chemoradiotherapy, especially 3D-CRT, is recommended in addition to surgery.

• Proceedings of the Korean Society of Fisheries Technology Conference
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• 2003.05a
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• pp.191-192
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• 2003

수산양식에 있어서 초기 치자어의 영양은 치자어의 생존 및 성장에 많은 영향을 미친다. 이와 같은 영양에는 주로 DHA와 EPA 등으로 많은 연구자들은 그 초점을 두고 있다. 그러나, 실제 어류에 있어서 부화 직후의 영양소 섭식 능력은 많은 종에 있어서 미지수로 종묘생산시 초기 감모기를 겪고 있으며 이 시기를 부화 후 first feeding 단계의 5∼10일로 잡고 있다. 그러나 이 초기 감모기를 지난 자치어는 rotifer와 Artemia 같은 살아있는 먹이생물을 이용하기에 충분하기 때문에 생존율에는 큰 영향이 없는 것으로 보고되어지고 있다. (중략)

• Korean Journal of Food Science and Technology
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• v.46 no.5
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• pp.655-659
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• 2014

Food-grade protective agents, namely, skim milk, yeast extract, soy powder, and trehalose, were studied for their ability to improve the viability of freeze-dried lactic acid bacteria (LAB), including Weissella cibaria SW1-1, Lactobacillus plantarum A-1, Lactobacillus sakei 2-12 24, and Leuconostoc citreum 3526. The best results were obtained with 10% soy powder; approximately 90% cell viability was observed during the freeze-drying process. Increase in the concentration of soy powder did not cause a proportional increase in the survival rate of LAB. Further, no significant difference was observed when two agents were combined in a 1:1 ratio (p<0.05).

• KOREAN JOURNAL OF CROP SCIENCE
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• v.53 no.4
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• pp.401-406
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• 2008

To select adoptable varieties in paddy soil with relatively high content of soil moisture, the growth characteristics and ginsenoside content of two-year-old ginseng was investigated in paddy soil with two types of drainage conditions such as poorly and imperfectly drained class, using 4 varieties, Cheonpoong (CP), Yeonpoong (YP), Hwangsookjong (HS) Jakyeongjong (JK). The ratio of survived plant in poor drainage conditions was higher than that in imperfect drainage conditions, and the ratio of discolored leaf in the former was lower than that in the latter. The ratio of survived plant was highest in HS, while lowest in YP. The ratio of discolored leaf was lowest in HS, while highest in YP among 4 varieties. Root weight per plant and yield were more distinctly decreased in poor drainage conditions than those in imperfect drainage conditions. Descending order of yield in poor drainage conditions was JK, CP, YP and HS, while CP, YP, JK and HS in imperfect drainage conditions. Varietal difference of rusty colored root was more distinct than that between poor and imperfect drainage conditions. The ratio of rusty colored root was relatively low in CP and JK, while high in YP and HS. Total ginsenoside content of two-year-old ginseng grown in poor drainage conditions was increased more than that in imperfect drainage conditions due to full growth of root. Regardless of different drainage conditions total ginsenoside content was highest in YP, while lowest in HS among 4 varieties, and there were no distinct difference between CP and JK.

• Journal of the Korean Applied Science and Technology
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• v.33 no.4
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• pp.658-666
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• 2016

We produced the Red ginseng residue water(RGW), ethanol(RGE), 1,3-butylene glycol(RGB) extract from Red ginseng residues, analyzed the components of the extracts by HPLC, and evaluated the cell viability on B16F10, antioxidant and anti-wrinkle effects for application of cosmetics. As a result, RGW, RGE, RGB have various ginsenoside and its content of RGB were higher than RGW, RGE as component analysis by using high performance liquid chromatography(HPLC). RGW showed similar with RGB in cell viability on B16F10 which were higher than RGE. DPPH radical scavenging activity increased according to the RGE>RGB>RGW. SOD-like activity increased according to the RGB>RGE>RGW. Also, elastase inhibition effect increased according to the RGW>RGB>RGE. These results suggested that RGB and RGW may have potential for the application of antioxidant and anti-wrinkle effects for cosmetics.

• The Journal of the Korean life insurance medical association
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• v.22
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• pp.55-98
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• 2003

본 연구는 질병별사망율연구(疾病別死亡率硏究)의 이론적 기초를 제시하고 일본 선진보험사의 질병별사망율연구(疾病別死亡率硏究)의 경험을 고찰하고 국내 보험사들의 질병사망율연관데이터의 현황분석을 통해 향후 질병별사망율연구(疾病別死亡率硏究)의 결과를 얻기 위해 현재 보험사들이 전사적으로 준비하여야 할 것에 대해 제언을 하고자 한다. 사망률연구(mortality study)란 인구통계학적 개념을 기본으로 하여 역학적 연구방법의 하나인 코호트방법과 생존분석방법을 결합하여 인구집단(또는 피보험자 집단)을 대상으로 대량의 자료를 장기적으로 관찰하여 그 사망의 빈도와 분포를 기술하고 사망연관지수들을 알아내어 생명보험사업에 있어서 위험선택기술을 향상시키는 것이다. 초과사망을 및 사망비 산출의 실제를 생명표 방법론과 급성심근 경색증 환자의 생존 분석을 통해 알아본다. 생명표 방법론을 이용한 생존 분석방법이란 의학저널에서 발표된 논문을 사망률표로 변경하기 위한 필수적인 단계에 대한 것이다 관찰된 생존 곡선을 생명표 작성법의 한 방법인 비교 경험 사망률로 바꾸는데 초점을 두었다. 일본생명(日本生命)의 경우, 일본 협영생명(協塋生命)의 경우, 일본사망율조사(MA)위원회 생명보험사망을 연구고서등을 통해 질병별사망율연구(疾病別死亡率硏究)를 살펴 보았다. 일본은 질병별사망율(疾病別死亡率)을 구하기 위해서 1950년대 이후부터 체계적으로 자료를 모으고 축적, 분석하여 지속성을 유지하였다. 또한 일본MA위원회의 경우처럼 보험의학의사, 계리, 통계, 전산부서로 구성된 전담위원회의 통일된 협조가 질병별사망율연구(疾病別死亡率硏究)를 가능하게 하였다. 그리고 의학적인 관점에서 볼 때 일본보험의학계는 일본만의 독특한 질병분류로 분석하여 온 것이 특이하다. 질병별사망율연구(疾病別死亡率硏究)에 대해서는 모두가 필요성을 인정하면서도 구체적인 대비책은 없는 것이 우리나라 보험업계의 실정이다. 이러한 현실의 직접적인 이유는 질병별사망율연구(疾病別死亡率硏究)라는 것이 그 특성상 중장기적인 계획이며 많은 전문인력의 통합되고 집중된 노력이 요구되기 때문이다. 우리도 "생명보험사사망율연구위원회(Life Insurance Mortality Committee" (가칭)를 설치하고 장기적인 계획안을 먼저 만드는 것이 선행되어야 할 것이다. 지금부터 질병별사망율(疾病別死亡率) 데이터를 축적하고 매 5년 또는 매 10년마다 데이터를 분석한다면 질병별사망율(疾病別死亡率)에 대해 고유의 기술을 습득하는 것이 그리 먼 미래의 일만은 아닐 것이다.

• Journal of agriculture & life science
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• v.46 no.2
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• pp.63-73
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• 2012

This study was conducted to investigate effects of fertilization treatments (non-fertilizing, deep-fertilizing 20g, 50g, 100g, and surface-fertilizing 20g) on survival rate, growth performances, and seedling quality index (SQI) of container seedling and bare root seedling of Pinus densiflora in the field. There were no significantly differences in survival rate among fertilization treatments in the field. Besides, there was no toxic effect on seedling by over 100g fertilization in deep-fertilizing treatment. The root collar diameter and height of P. densiflora in both seedling types were the highest at 100g fertilization in deep-fertilizing treatments, and the biomass products and SQI were the same as above growth of root collar diameter and height. In most of the treatments, container seedlings showed better growth performances than bare root seedlings. In optimal fertilization, effect of fertilization was higher in container seedling than bare root seedling.

• The Science & Technology
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• v.31 no.4 s.347
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• pp.70-71
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• 1998

면역 억제제인 「마이크로 에멀션 제제기술 」을 개발한 한미약품 중앙연구는 다국적기업인 노바티스사로부터 향후 20년 총 2천억원 규모의 로열티를 받게 되었다. 장기의식 후에 따르는 조직이식거부반응을 막아 환자의 생존율을 늘려주는 획기적인 면역억제제의 신기술 개발은 "세계최고의 위업"이라는 평을 받고 있다. 외환에 시달리는 요즘 막대한 달러의 로열티는 시민들의 주름살을 펴주는 낭보가 아닐 수가 없다.

• Korean Journal of Environmental Biology
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• v.40 no.3
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• pp.275-280
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• 2022

Suspended solids play an important role in the growth and survival of aquatic organisms. The marine zooplankton species tested in this study were Tigriopus west (Copepoda) and Haustorioides koreanus (Amphipoda) sampled from the intertidal zone, including Artemia nauplii(Branchiopoda) hatched from cysts. The study design included six concentrations (0, 50, 100, 250, 500, and 1,000mg L^-1) of the suspended test particles assayed in triplicate. Experimental cultures in 500 mL-round polycarbonate bottles were subsampled after 96 h to count dead zooplankton. The culture bottles were agitated at 4 RPM on a rotating wheel at 23℃ and 30 PSU. The survival rates of Artemia nauplii and T. west were not affected by suspended solid concentrations higher than 50.0 mg L^-1, whereas the survival rate of H. koreanus decreased with increasing concentrations (p<0.05). In conclusion, H. koreanus and T. west, which were continuously exposed to suspended solid concentrations higher than 50.0 mg L^-1, were affected by low-intensity ecological stress. However, in the case of H. koreanus, a concentration of 50.0 mg L^-1 may be considered to be the limit of tolerance to suspended solids, suggesting that the number of individuals who eventually die will increase if continuously exposed.

• Proceedings of the Korean Society of Fisheries Technology Conference
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• 2000.05a
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• pp.508-509
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• 2000

우리나라의 굴 양식업은 1970년대 수하식 굴 양식기술 개발보급으로 계속 증대 발전하였으나, 연안의 산업화와 도시화에 의한 수질환경 악화 그리고 장기간의 집약적 양식에 의한 어장 노화와 양식 굴의 품종 열화 등에 원인하여 1990년대에 들어서면서 양식 생산량이 점차 감소하는 경향을 보이고 있다. 따라서 굴 양식의 지속적 생산 방안의 모색을 위하여 환경 적응력이 강한 굴 품종을 선발하고 변화된 어장환경을 이해하고자, 산지별 굴의 양성 해역별 양성시험을 실시하여 굴의 성장도, 비만도 및 생존율의 비교 조사와 그리고 환경조사 등을 실시하였다. (중략)