• Tuberculosis and Respiratory Diseases
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• v.48 no.1
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• pp.33-44
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• 2000

Background: To evaluate airway responses and inflammation to antigen in Sprague-Dawley rat asthma model, we examined airway responses, serial histologic changes of the lung, and the relationship between airway responses and airway inflammation after antigen airway challenge. Methods: Sprague-Dawley rats were sensitized with subcutaneous injection of 10 ${\mu}g$ ovalbumin(OA). Antigen airway challenges were done 14~16 days after sensitization and the sensitized rats were sacrificed 1h($A_E$), 6~8h($A_L$) and 1day($A_D$) after airway challenge, to examine the histologic changes of the lung. Airway responses were measured by body plethysmograph and recorded by enhanced pause(Penh) as an index of airway obstruction 6~8h after antigen challenges. Nonsensitized controls(10 rats) were also challenged with antigen and sacrificed 1 day later. Histopathologic examination of two trachea, large bronchi, small bronchi, and vessels was performed to evaluate the severity of inflammation and eosinophilic infiltration with H&E stain. Results: In 17 of 20 rats(85%) in both groups, we observed airway responses. Among them, an early response(ER) in 15 rats(75%), an dual response in 5(25%), and an late response(LR) only in 2 rats(10%) displayed. There were no significant differences in the severity of inflammation among the trachea, large bronchi, small bronchi and vessels in all groups after antigen challenge(p>0.05) and between early and late responders. The significant eosinophil infiltration was observed in 5 rats(50%) of AL(p<0.05) compared with in AE and controls. Also, eosinophil infiltration was observed in higher trend in LR(57.1%) compared to ER(40%)(p>0.05). Conclusion: Sprague-Dawley rats sensitized with subcutaneous injection of OA showed a significant airway responses to antigen challenge. But antigen challenges caused a little eosinophil infiltration and no significant airway inflammation. Asthma model of Sprague-Dawley rats could be useful for antigen-induced airway responses, but this model has a limitation for the study of human asthma because of no significant pathologic change.

• Proceedings of the KAIS Fall Conference
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• 2011.05b
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• pp.1061-1063
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• 2011

본 연구는 병원전 단계 기도기 시뮬레이션 교육에 대한 연구로 연구대상은 응급구조학과 4학년 학생 22명으로 구성하였다. 교육시간은 10분 동안 3개의 기도유지기에 대한 전체 강의가 있었고, 10분 동안 마네킹을 이용하여 세 가지 기도기의 사용방법을 교육하고 실습을 시행하였다. 응급구조학과 학생을 대상으로 Airway management trainer Simman를 이용한 기도 내 이물 제거 모델에서 매킨토시후두경과 GlideScope and the AWS$^{(R)}$, McGrath$^{(R)}$ 비디오 후두경의 기관내 삽관 성공률과 삽관 시간, 시행자의 선호도를 비교한 결과 의미 있는 차이를 보였다. 마네킨을 이용한 병원전 기도기인 1차 시도에서는 유의한 차이를 보였지만 2차에서 숙련이 된 경우이라서 큰차이를 보이지 않았다. 기관내 삽관 기구의 선호도 조사에서는 Pentax AWS를 가장 선호하였다.

• Journal of Korea Multimedia Society
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• v.6 no.6
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• pp.991-999
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• 2003

In this paper, we proposed image acquisition techniques that can reflect anatomical airway information lot breath change by EBCT Also, we proposed new method to detect automatically boundary of inner airway for acquired slice images using this image acquisition technology. We confirmed that new method detects boundary of inner airway effectively through computer simulation that apply image data about each slice position of airway. And, we could see change for cross section area of inner airway by time change. Therefore, we think that proposed method can utilize on quantitative analysis in clinical field.

• Tuberculosis and Respiratory Diseases
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• v.50 no.4
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• pp.462-472
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• 2001

Background : The determinants of intubation and the response to therapy in COPD patients with hypercapnic respiratory failure were retrospectively reviewed. Methods : This study involved a review of 132 episodes of hypercapnic respiratory failure($PaCO_2\;{\geq}\;50\;mmHg$ and $pH\;{\leq}\;7.35$). The time frame for resolution or the time to intubation of patients who were admitted between 1996 and 1999 was analyzed. Results : Out of 132 hypercapnic episodes, 49(37%) required intubation. A comparison was made with the 83 cases that responded to treatment. Patients requiring intubation had a greater severity of illness, which included a higher APACHE II (Acute Physiology and Chronic Health Evaluation II) score ($20{\pm}5$ vs $14{\pm}4$ ; p<0.01), a higher WBC, a higher serum BUN, and greater acidosis (pH, $7.23{\pm}0.11$ vs $7.32{\pm}0.04$ ; p<0.01). Those with the most severe acidosis(pH<7.20) had the highest intubation rate(87%) and shortest time to intubation($2{\pm}3\;h$). Conversely, those with an initial pH 7.31 to 7.35 were less likely to be intubated(20%), and had a longer time to intubation($97{\pm}121\;h$). The patients with a pH 7.21 to 7.25($4.1{\pm}2.9$ day) required longer period of time to respond to medical treatment than patients with a pH of 7.31 to 7.35($2.2{\pm}3.1$ day). Of those patients requiring intubation, half(55%) were intubated within 8 h of admission, and most (75%) within 24 h. Of those patients responding to treatment medical therapy, half(52%) recovered within 24 h and most (78%) recovered within 48 h. Conclusion: Respiratory acidosis at the initial presentation is associated with an increased likelihood of intubation. This should assist in deciding help with the decision whether to treat patients medically, institute noninvasive ventilation, or proceed to intubation.

• The Korean Journal of Nuclear Medicine
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• v.32 no.3
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• pp.276-289
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• 1998

Purpose: To evaluate dysphagia objectively and quantitatively, and to clarify the effect of neck position and viscosity changes in patients with aspiration and laryngeal penetration. Materials and Methods: We studied 35 patients with dysphagia and 21 normal controls using videofluoroscopy and scintigraphy. Videofluoroscopy was performed with barium with three different viscosity, and scintigraphy was done with water, yogurt, and steamed egg mixed with Tc-99m tin colloid. If aspiration was found during videofluoroscopic examination, patient's neck position was changed and study repeated. Videofluoroscopy was analyzed qualitatively. We calculated 7 quantitative parameters from scintigraphy. According to the videofluoroscopic findings, we divided patients into 3 subgroups; aspiration, laryngeal penetration, and no-aspiration group. Results: The result of videofluoroscopy revealed that the most common finding was the delay in triggering pharyngeal swallow. Pharyngeal transit time (PTT) and pharyngeal swallowing efficiency(PSE) in patients with aspiration were signifi-cantly different from other groups. After neck position change, aspiration could be reduced in all of 7 patients, and laryngeal penetration reduced by about 82%. PTT and PSE were also improved after position change. Aspiration and laryngeal penetration occurred more frequently in thin liquid swallowing than in thick liquid and solid swallowing. Conclusion: PTT and PSE were useful for the evaluation of dysphagia. Aspiration and laryngeal penetration could be reduced when appropriate position assumed. We could decrease the chance of aspiration by changing the patient diet consistency. Scintigraphy might be useful tool to quantitate and follow up these changes.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1981.05a
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• pp.3.3-4
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• 1981

We have observed foreign body in food and air passage in 138 cases during the period from Jan. 1972 to Dec. 1980 in E.N.T. department of Kyung Hee university hospital. The following results were obtained. 1) Age distribution was predominent in under 5 years old showing 102 cases (73.9%). 2) Distribution of location was 132 cases in food passage and 6 cases in air passage. 3) In food passage, malewas 81 cases (61.4%). In air passage, male was 4 cases(66.7%). 4) Coin was the most frequent foreign body in food passage. Others were metals, meats, bony pieces, and shell. 5) Distribution of lodgement was frequent in first narrowing of esophagus. 6) Duration of lodgement was 112 cases (84.8%) within 24 hours in food passage and 4 cases (66.7%) within 24 hours in air passage.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1995.04a
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• pp.93.1-93
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• 1995

저자들은 1985년 9월부터 1995년 2월까지 계명대학교 의과대학 이비인후과에 내원한 환자중 기도이물을 의심하여 환기형 기관지경술을 시행한 54례의 유소아 환자들을 대상으로 임상적 고찰을 하여 다음과 같은 결론을 얻었다.1) 기도이물을 의심한 환자 54례중 4세 이하가 49례(90.7%)로 대부분을 차지하였고, 남녀의 비는 3.5:1 이었다. 2) 이물개재 시간별 분포는 7일에서 30일 이내가 13례(24.0%)로 가장 많았고 다음이 2일에서 3일이내로 12례(22.2%)였다. 3) 기도이물의 증상으로는 기침(85.1%), 호흡곤란(38,9%), 고열(31.5%) 등의 순이었다. 4) 기도이물의 종류로는 식물성이 23례(67.6%)로 가장 많았고, 이중 땅콩이 19례였으며, 금속류, 플라스틱류 순이었다. 5) 이물이 있었던 34례중 흉부단순 X-선 소견상 이상소견을 나타낸 경우는 32례(94.1%)였으며, 이중 폐기종이 가장 많은 빈도를 보였고, 식물성이물은 전례에서 이상소견을 보였다. 6) 기도이물을 의심한 환자 54례중 이물이 없었던 20(37.0%)례 모두 흉부단순 X-선 소견상 이상소견을 나타내었고 이중 폐렴이 10례(50%)로 가장 많았고 무기폐, 페기종의 순이었다. 7) 이물의 개재부위는 주기관지 26례(우:14, 자:12), 기관 6례, 성문 2례의 순이었다.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1982.05a
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• pp.6.2-7
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• 1982

We have observed foreign bodies in food and air passage in 270 cases during the period from Sep. 1976 to Aug. 1981 in E.N.T. department of Han Gang Sacred Heart Hospital. The following results were obtained. 1) Distribution of location was 256 cases (94.8%) in food passage and 14 cases(5.2%) in air passage. 2) Age distribution was predominent in under 5 years old showing 198 cases(77.7%) in food passage and 10 cases (71.4%) in air passage. Under 5 years old group in the cases of food passage, coin was the most frequent material : 175 cases(87.9%), and in the cases of air passage, plastic material was the most frequent material : 5 cases(50.0%). Over 40 years old group in the cases of food passage, bony pieces was the most frequent material : 8 cases(47.1%), and meats was second frequent material: 6 cases. 3) Male seems to be more frequently involved than female in cases of food and air passage. Food passage - Male: Female - 151 : 105 (1.4:1) Air passage - Male : Female - 10:4 (2.5:1) 4) Coin was the most frequent foreign body in food Passage (199 cases-77.7%). Others were metals, bony pices, and meats. Plastic material was the most frequent foreign body in air passage (7 cases-50%). 5) In the locality of food passage, the first narrowing of the esophagus was the most frequent site, and air passage, the bronchus-especially right bronchus-was the most frequent site. 6) During of lodgement was 218 cases (85.2%) within 24 hours in food passage and 9 cases (64.3%) within 24 hours in air passage, and in air passage one case visited 5 months later after the accident.

• Journal of Digital Convergence
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• v.14 no.9
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• pp.43-51
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• 2016

The purpose of this study is to find out what are the factors that influence christian characteristics among christian theology major and non major students. Among the diversity factors, especially focused on studies of faith character variable and satisfaction of chapel, and how much these factors affect and how it correlates and what affects the most between christian theology major and non major students. This study has been surveyed to students who are enrolled in B University. As a result, christian theology major students have larger portion of Christian characteristics than non major students. Additionally students who are satisfied with chapel, having personal prayer time, meditation time, spending longer hour with bible and involving church activities have highly established christian personalities upon students.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1976.06a
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• pp.88.2-89
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• 1976

Clinical observation is made on the total 205 cases of foreign bodies in the air and food passages. The entire foreign body cases that had visited ENT Dept. of Han Gang Sacred Heart Hospital from January, 1972 to March, 1976 are included in this study. The results summarized are as follows: 1) The majority of the cases of foreign bodies are found in the food passage, 200 cases (97.6%) while in the air passage only 5 cases was present. 2) The most common foreign bodies in the esophagus was coin (90%) and in the air passage, the sorts of foreign bodies are bean, peanut, plastic bullet, corn and towel clip. 3) In the locality of foreign bodies, the first narrowing is the most frequent site in the esophagus. 4) The majority of the cases with esophageal foreign body is male (M:F 1.4 : 1), in the air passage (M:F 3:2). 5) The patients with esophageal foreign body visited within 3 days in 87%, and with trachiobronchial foreign body visited within a day in all cases.