• Proceedings of the Korea Society for Simulation Conference
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• 2004.05a
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• pp.118-122
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• 2004

본 논문에서는 인체의 머리 부분을 촬영한 의료 영상에서 뇌 영역만을 분할하는 방법에 대해 제시하고자 한다. 뇌의 해부학적 구조 및 기능적 이상 부위를 파악할 경우에 영상 내에 함께 보여지는 두개골과 뇌척수액 등을 제외한 대뇌피질 영역을 분할하면 보다 효과적인 정보 분석 및 진단이 가능하게 된다. 본 시스템에서는 3단계 알고리즘을 제시한다. 첫 번째 단계에서는 영상 내에 존재하는 잡음을 제거하기 위한 필터링이고, 두 번째 단계에서는 필터링된 결과에 대한 영상분할을 수행하는 것이다 이 때 정확한 결과 도출을 위하여 사용자의 인터렉션이 들어가게 된다. 세번째 단계에서는 형태학적 방법을 이용하여 분할 결과를 보완한다. 본 연구를 위한 실험에는 자기 공명 촬영 영상(MRI: Magnetic Resonance Imaging), 단일 광전자 방출 단층 촬영영상(SPECT: Single Photon Emission Computed Tomography), 양전자 방출 단층 촬영영상(PET: Positron Emission Tomography) 등을 사용하였다. 본 시스템에서는 다양한 모달리티의 뇌 영상에서 대뇌피질 부분을 정확하게 영상 분할함으로써 뇌의 구조적 이상을 판단하기 위한 해부학적 정보 분석을 가능케 하고 있다. 뿐만 아니라 뇌 질환에 대한 정확한 진단 시뮬레이션도 가능하게 하고자 한다.

• Proceedings of the Korea Contents Association Conference
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• 2017.05a
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• pp.475-476
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• 2017

손상된 조직이나 부위를 원상태로 회복하기 위한 대제 물질인 생체재료 개발에 관한 연구가 꾸준히 이루어지고 있다. 이러한 생체재료는 생체내에서 기능을 수행하기 위한 기계적 특성과 생물학적 특성을 갖추어야 한다. 생분해성 고분자는 금속재료에 비해 우수한 분해성으로 널리 사용되고 있다. 그러나 대부분의 생분해성 고분자는 약한 기계적 특성으로 사용범위가 제한적이다. 문제점의 해결을 위해 hydroxyapatie와 TCP등을 활용한 방법이 제시되어왔다. 이에 본 연구는 ${\beta}-TCP$ 첨가량에 따른 세라믹/고분자 복합체를 제조하여 다양한 기계적 효과를 평가하였다.

• Proceedings of the Korean Reliability Society Conference
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• 2004.07a
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• pp.297-301
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• 2004

세탁기의 Shaft Ass'y는 모터로부터 동력을 전달 받아 세탁 및 탈수행정의 제어 기능을 수행하는 세탁기의 핵심부품으로 사용 중 브레이크 밴드소음을 유발하여 소비자의 불만족 요소로 작용하고 있다. 그러나 드럼과 브레이크 페드의 정확한 마찰소음 현상 규명이 안되어 불량 개선에 많은 어려움이 있다. 이를 해결하고자 소음, 진동, 소재 분석 및 ESPI(Electronic Speckle Pattern Interferometry) 분석을 통해 고장원인을 규명하였다. 특히 ESPI는 비접촉, Full Field 정밀 변형 가시화 장치로 Shaft Ass'y의 동작 중 공진소음 발생 부위를 변형 가시화를 통해 정확하게 찾을 수 있었다. 밴드소음 원인은 브레이크 Lever의 공진에 의해 발생하였고 브레이크 밴드 패드의 접촉면적 불균일로 인한 국부적 마찰력 증대가 소음원으로 작용하였다. 밴드소음의 정확한 고장 메커니즘 규명을 통해 개선안을 도출하여 적용하였고 밴드소음 개선효과를 얻을 수 있었다.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2014.10a
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• pp.501-504
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• 2014

자동차의 하중을 지탱하고 자동차의 방향 전환 유지와 노면 충격을 흡수 완화하며, 엔진의 구동력과 브레이크 작동 시 제동력을 노면에 전달하는 등의 기능을 수행하는 타이어의 상태는 안전과 직결되어 있다고 볼 수 있다. 주행 중 타이어의 불량으로 인한 사고는 무시할 수 없는 부분을 차지한다. 타이어의 편마모는 주행 안전성을 위한 타이어의 문제 중 하나로 운전자의 운전습관과 휠얼라이먼트의 이상 등으로 타이어의 특정 부위가 마모되는 증상을 말하는데, 객관적으로 정확하게 검증할 수 있는 측정방법이 없는 것이 현실이다. 본 논문에서는 현실의 주관적인 검증기준의 단점을 보완하고 키넥트 센서를 이용하여 각 타이어의 마모 정도를 체크하여 편마모를 객관적으로 검증할 수 있는 시스템을 설계하고자 한다.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.7
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• pp.487-495
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• 2020

This study examined the effects of auricular acupressure on female college students with functional constipation to propose auricular acupressure as an effective and evidence-based nursing intervention. This is an experimental study designed with randomization and single-blind in a Sham-control approach. The subjects included 44 female college students with functional constipation whose symptoms met the Rome IV criteria. In this study, five different acupressure sites were applied to each group; the experimental group (n=23) received auricular acupressure on rectum, large intestine, lung, san jiao, and shenmen, whereas the Sham control group (n=21) received acupressure on ankle, helix, tooth, jaw, and external ear. The intervention was implemented once a week for a total of six weeks. After six weeks, the severity of constipation, stool form, and quality of life regarding constipation in the experimental group significantly improved compared to that of the Sham control group (p<.001). Consequently, the study showed that auricular acupressure can be used as an effective nursing intervention to alleviate constipation in female college students.

• Journal of the Korea Society of Computer and Information
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• v.14 no.10
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• pp.159-166
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• 2009

A nature immunity system responds sensitively to an external invasion with various functions in a lot of bodies, besides it there is a function to remember information to have been currently infected. we propose a hybrid model similar to immune system which combine with the antibody which applied genetic algorithm as select antibody and the arbitrary abnormal system call sequence that applied negative selection of a nature immunity system. A proposed model uses an arbitrary abnormal system Kol sequence in order to reduce a positive defect and a negative defect. Data used to experiment are send mail data processed UNM (University of New Maxico). The negative defect that an experiment results proposal model judged system call more abnormal than the existing negative selection to normal system call appeared 0.55% low.

• Korean Journal of Construction Engineering and Management
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• v.19 no.6
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• pp.115-123
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• 2018

The primary objective of this study is to develop an all-in-one based steel pipe pile cutting robot prototype that improves the conventional steel pipe pile head cutting work in safety, quality, and productivity. For this, the following research works are conducted sequentially; 1)literature review and expert survey, 2)selection of core technology using AHP analysis, 3)deduction of detail design, 4)verification of structural stability, 5)development of full-scale prototype. As a result leveling laser and laser detector(94.46), plasma cutter(96.72), rotary grapple(98.45) are selected as a core technologies. As an outcome, it is analyzed that gripper, cylinder pivot bracket and gripper base are structurally stable. Their maximum stresses are shown as 43.0%, 19.4%, 5.3% compared to their yield strength respectively. The development of full-scale prototype in this study will be utilized for the development of the all-in-one attachment based steel pipe pile cutting robot commercialization model.

• Journal of environmental and Sanitary engineering
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• v.1 no.1 s.1
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• pp.69-79
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• 1986

This studies were carried out to investigate the high infection sites from various specimens, cultural isolation on the susceptible media and specific antibody titres of M. pulmonis in experimental 310 mice and 330 rats obtained from two breeding facilities. Efficiency of complement faxation test (CF test) for detection of M. pulmonis antibody in mice and rats were compared directly with the diagnostic cultural isolation method. 1. Isolation rates of M. pulmonis among infection sites were about 30% from the oral cavities and $40\%$ from the middle ear of mice. The rates were $100\%$from the nasal cavaties and $90\%$ from the oral cavities of rats. 2. The infection rates were $12\%$ to A group and $16\%$ to B group of mice. The rates in the rats were $55\%$ to A group and $70\%$ to B group. 3. The M. pulmonis antibody titres by CF test were $73\%$ of total 100 mice in serum dilution below 1:5 (< 1:5), and $24\%$ of total samples in antibody titres above 1:5 (> 1:5), but 3 samples were not showed anticomplementary activities. The antibody titres in rats were $35\%$ of 120 rats in below 1:5 (< 1:5), and $61\%$ of total samples in above 1:5 (> 1:5), but the remained were not showed anticomplementary activities.

• Korean Journal of Microbiology
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• v.38 no.3
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• pp.153-161
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• 2002

Sox4, a transcription factor, consists of three functional domains: an HMG-box domain as a DNA binding domain, serine rich region as a transactivation domain and glycine rich region (GRR), an unknown functional domain. Although Sox4 is known to be functionally involved in heart, B-cell and reproductive system development, its physiological function remains to be elucidated. We used pGEX expression system to develop a simple and rapid method for purifying Sox4 protein in suitable forms for biochemical studies of their functions. Unexpectedly, we observed that full-length Sox4 appears to be protease-sensitive during expression and purification in E. coli. To map the protease-sensitive site in Sox4, we generated various constructs with each of functional domains of Sox4 and purified as the GST-Sox4 fusion proteins using glutathione beads. We found that the specific cleavage site for the proteolytic enzyme, which exists in E. coli, is localized within the novel GRR of Sox4. Our study suggest that the GRR of Sox4 may a target for the cellular protease action and this cleavage in the GRR may be involved in regulating physiological function of Sox4. Additionally, our study may provide a useful method for investigating the proteolytic cleavage of the target molecule in E. coli.

• Investigative Magnetic Resonance Imaging
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• v.13 no.1
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• pp.40-46
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• 2009

Purpose : The purpose of this study was to investigate the quantitative evaluation of the corticospinal tract (CST) at the multiple levels by using functional MRI (fMRI) co-registered to diffusion tensor tractography (DTT). Materials and Methods : Ten normal subjects without any history of neurological disorder participated in this study. fMRI was performed at 1.5 T MR scanner using hand grasp-release movement paradigm. DTT was performed by using DtiStudio on the basis of fiber assignment continuous tracking algorithm (FACT). The seed region of interest (ROI) was drawn in the area of maximum fMRI activation during the motor task of hand grasp-release movement on a 2-D fractional anisotropy (FA) color map, and the target ROI was drawn in the cortiocospinal portion of anterior lower pons. We have drawn five ROIs for the measurement of FA and apparent diffusion coefficient (ADC) along the corona radiata (CR) down to the medulla. Results : The contralateral primary sensorimotor cortex (SM1) was mainly found to be activated in all subjects. DTT showed that tracts originated from SM1 and ran to the medulla along the known pathway of the CST. In all subjects, FA values of the CST were higher at the level of the midbrain and posterior limb of internal capsule (PLIC) than the level of others. Conclusion : Our study showed that co-registered fMRI and DTT has elucidated the state of CST on 3-D and analyzed the quantitative values of FA and ADC at the multiple levels. We conclude that co-registered fMRI and DTT may be applied as a useful tool for clarifying and investigating the state of CST in the patients with brain injury.