• 대한두경부종양학회:학술대회논문집
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• 1989.11a
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• pp.20.1-20.1
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• 1989

• 대한두경부종양학회:학술대회논문집
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• 1992.11a
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• pp.137-138
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• 1992

• The Korean Journal of Cytopathology
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• v.8 no.1
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• pp.103-107
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• 1997

Initial rapid diagnosis of primary pulmonary cryptococcosis(PPC) occurring in a immunocompetent host was made by transthoracic fine needle aspiration cytology of a solitary subpleural nodule. Numerous refractile spherical organisms surrounded by a clear halo were demonstrated with haematoxylin-eosin and Papanicolaou stains. The organisms, $5{\sim}15{\mu}m$ in diameter, were easily demonstrated with Gomori methenamine-silver stain. Many of the organisms showed narrow-base budding. Carminophilic cell walls were well demonstrated with mucicarmine stain.

• Proceedings of the KOR-KST Conference
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• 1999.10a
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• pp.287-290
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• 1999

• Journal of Chest Surgery
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• v.20 no.3
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• pp.593-597
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• 1987

Mesothelioma is a primary tumor of the pleura. There are two forms of mesotheliomas; diffuse form and localized form. The majority of localized mesotheliomas are benign, but the tumor with pedicle recur at 20% after removal of it. Malignant localized fibrous mesothelioma is differential diagnosed pathologically and clinically with diffuse mesothelioma. Symptoms of localized mesothelioma are generally related to the size of the tumor. We presented one case of malignant localized fibrous mesothelioma. The patient was 32 years old female and chief complaints were dyspnea and dry cough. Sputum cytology and needle lung biopsy were not able to diagnose definitely the tumor. Explothoracotomy was carried out for definite tissue biopsy. At the time of operation, huge adult head size mass was in the right thoracic cavity. The surface of the mass was nodular, multilobular and had hard consistency. Pedicle was formed above first rib and its diameter was 4.5cm. There was no adhesion except to RUL. Frozen biopsy suggested mesothelioma. Extirpation of the mass, right upper lobectomy. and partial pleurectomy were carried out.

• The monthly packaging world
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• s.54
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• pp.160-171
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• 1997

보호성, 편리성 등의 주로 원초적인 기능에 국한되어 발전해 온 종래의 포장이 근자에 와서는 각종 인쇄재와 인쇄술의 발전에 편승하여 괄목할만큼 향상된 미적 기능을 갖게 되었음은 주지의 사실이다. 그러나 마아케팅의 유력한 수단이 되고 있는 현대의 포장은 그 존속의 가치가 이러한 원초적이고도 미의식 중심의 기능으로만 편향되어서는 안되며, 품질과 가격 등의 제품 자체의 경쟁력에 못지 않은 고객의 구매행위에 보다 직접적이고도 결정적인 소구작용을 할 수 있도록 창

• Communications of Mathematical Education
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• v.18 no.3 s.20
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• pp.73-80
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• 2004

이 연구에서는 초등학교 1학년 수학영재학생들을 위한 심화학습 자료를 개발하였다. 개발된 학습 자료에는 다양한 활동 중심과 간학문적 접관을 통하여 수학에 대한 흥미를 증진시진 수 있는 내용을 포함시켜 지적영역에만 국한되는 편협성을 탈피하여 보다 창의성을 신장하도록 하였다.

• Radiation Oncology Journal
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• v.16 no.3
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• pp.291-301
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• 1998

Purpose : A retrospective study was conducted comparing single daily fraction (SDF) thoracic radiotherapy (TRT) with twice daily (BID) TRT to determine the potential benefit of BID TRT in limited-stage small cell lung cancer (SCLC). Endpoints of the study were response. survival, pattern of failure, and acute toxicity. Materials and Methods : Between November 1989 to December 1996, 78 patients with histologically proven limited-stage SCLC were treated at the Department of Therapeutic Radiology, Chungnam National University Hospital. Of these, 9 were irradiated for palliative intent, and 1 had recurrent disease. Remaining 68 patients were enrolled in this study. There were 26 patients with a median age of 58 years, and 22 (85$\%$) ECOG performance score of less than 1 in SDF TRT. There were 42 patients with a median age of 57 years, and 36 (86$\%$) ECOG performance score of less than 1 in BID TRT By radiation fractionation regimen, there were 26 in SDF TRT and 42 in BID TRT. SDF TRT consisted of 180 cGy, 5 days a week. BID TRT consisted of 150 cGy BID, 5 days a week in 13 of 42 and 120 cGy BID, in 29 of 42. And the twice daily fractions were separated by at least 4 hours. Total radiotherapy doses were between 5040 and 6940 cGy (median, 5040 cGy) in SDF TRT and was between 4320 and 5100 cGy (median, 4560 cGy) in BID TRT. Prophylactic cranial irradiation (PCI) was recommended for patients who achieved a CR. The recommended PCI dose was 2500 cGy/10 fractions. Chemotherapy consisted of CAV (cytoxan 1000 mg/$m^2$, adriamycin 40 mg/$m^2$, vincristine 1 mg/$m^2$) alternating with VPP (cisplatin 60 mg/$m^2$, etoposide 100 mg/$m^2$) every 3 weeks in 25 (96$\%$) of SDF TRT and in 40 (95$\%$) of BID TRT. Median cycle of chemotherapy was six in both group. Timing for chemotherapy was sequential in 23 of SDF TRT and in 3 BID TRT, and concurrent in 3 of SDF TRT and in 39 of BID TRT Follow-up ranged from 2 to 99 months (median, 14 months) in both groups. Results : Of the 26 SDF TRT, 9 (35$\%$) achieved a complete response (CR) and 14 (54$\%$) experienced a partial response (PR). Of the 42 BID TRT, 18 (43$\%$) achieved a CR and 23 (55$\%$) experienced a PR. There was no significant response difference between the two arms (p=0.119). Overall median and 2-year survival were 15 months and 26.8$\%$, respectively. The 2-year survivals were 26.9$\%$ and 28$\%$ in both arm, respectively (p=0.51). The 2-rear survivals were 35$\%$ in CR and 24.2$\%$ in PR, respectively. The grade 2 to 3 esophageal toxicities and grade 2 to 4 neutropenias were more common in BID TRT (p=0.028 0.003). There was no difference in locoregional and distant metastasis between the two arms (p=0 125 and 0.335, respectively). The most common site of distant metastasis was the brain. Conclusion : The median survival and 2-year survival were 17 months and 20.9$\%$ in SDF TRT with sequential chemotherapy, and 15 months and 28$\%$ in BID TRT with concurrent chemotherapy, respectively. We did not observe a substantial improvement of long-term survival in the BID TRT with concurrent chemotherapy compared with standard schedules of SDF TRT with sequential chemotherapy. The grade 2 to 3 esophageal toxicities and glade 2 to 4 neutropenias were more common in BID TRT with concurrent chemotherapy. Although the acute toxicities were more common in BID TRT with concurrent chemotherapy than SDF TRT with sequential chemotherapy, a concurrent chemotherapy and twice daily TRT was feasible. However further patient accrual and long-term follow up are needed to determine the potential benefits of BID TRT in limited-stage SCLC.

• Radiation Oncology Journal
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• v.20 no.1
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• pp.17-23
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• 2002

Purpose : To clarify the clinical benefit derived from the combined modality therapy (CMT) consisting of chemotherapy (CT) and involved field radiotherapy (RT) for stage I and II angiocentric lymphomas of the head and neck. Materials and Methods : Of 143 patients with angiocentric lymphoma of the head and neck treated at our hospital between 1976 and 1995, 104 patients (RT group) received involved field RT alone with a median dose of 50.4 Gy (range : 20~70 Gy), while 39 patients (CMT group) received a median 3 cycles (range : 1~6 cycles) of CT before involved field RT. The response rate, patterns of failure, complications, and survival data of the RT group were compared with those of the CMT group. Results : Despite a higher response rate, local failure was the most common pattern of failure in patients of both groups. The patterns of failure, including the systemic relapse rate were not influenced by the addition of combination CT. Although both modalities were well tolerated by the majority of patients, aberrant immunologic disorders or medical illnesses, such as a hemophagocytic syndrome, sepsis, intractable hemorrhage, or the evolution of second primary malignancies were more frequently observed in patients of the CMT group. The prognosis of patients in the RT group was relatively poor, with a 5-year overall actuarial survival rate of 38% and disease-free survival rate of 32%, respectively. However, their clinical outcome was not altered by the addition of systemic CT. Achieving complete remission was the most important prognostic factor by univariate and multivariate analyses, but treatment modality was not found to be a prognostic variable influencing survival. Conclusions : Involved field RT alone for angiocentric lymphoma of the head and neck was insufficient to achieve an improved survival rate, but the addition of CT to involved field RT failed to demonstrate any therapeutic advantage over involved field RT alone.

• Science of Emotion and Sensibility
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• v.2 no.2
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• pp.93-104
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• 1999

대부분의 제품디자인관련 종사자들은 제품심미성이 소비자의 제품선호에 중요한 영향을 미친다는 주장에 동의하고 있다. 그러나 기존 연구들이 많은 기여를 했다고 볼 수 있으나 제품 심미성을 어떻게 평가 할 것인가\ulcorner 소비자 반응에 대한 그 영향을 어떻게 측정 할 것인가\ulcorner 에 대한 연구가 미미한 편이다. 따라서 본 연구는 제품디자인에 대한 소비자의 선호에 대한 심미성 차원의 영향을 탐색하고, 남성용 화장품 용기의 심미성 차원에 대한 소비자 인식의 측정을 통한 실증적 결과를 보여준다. 이 연구가 남성용화장품용기에 국한되었다 할지라도 다른 다양한 제품의 심미성 역할에도 확대 적용될 수 있을 것이다.