• Journal of Oral Medicine and Pain
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• v.38 no.1
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• pp.19-28
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• 2013

With Korea's rapid entry to aged society, elderly population has become a major age group both in the whole society and medical field and its importance will be constantly stressed out. Elderly population is also important in the field of oral medicine which deals with chronic and recurrent diseases in the orofacial region of non-dental origin but there exist few studies indicating epidemiology of elderly patients in this regards. This study aimed to investigate change of age distribution of new patients in a university-based dental hospital and oral medicine clinic for last decade and to investigate clinical epidemiology of elderly patients (${\geq}$ 65 years) of oral medicine clinic. This study was performed retrospectively using medical records of the new patients in Dankook University Dental Hospital in 2001 and 2011. According to the study, percentage of elderly new patients increased in both dental hospital and oral medicine clinic and degree of the increase was greater in oral medicine clinic than in the whole hospital (p=0.000). 13.5% of adult patients ${\geq}$ 18 years of oral medicine clinic were elderly patients ${\geq}$ 65 years. 83% of elderly patients were suffering from one or more systemic diseases. Although TMD was the most common reason for elderly patients who visited oral medicine clinic, oral soft tissue diseases, dry mouth, burning mouth syndrome and oromandibular dystonia was more frequently diagnosed in elderly patients compared to adult patients aged 18 to 64 years. Pain severity and interference of Brief Pain Inventory and depression and anxiety scores of Hospital Anxiety Depression Scales were higher in elderly patients than in the adult patients (p<0.05). Increase of elderly patients with chronic oral diseases and pain needs more attention of dentists and specialists of oral medicine to improvement of assessment and development of tailored management because large portion of the elderly patients have systemic diseases, polypharmacy and impaired communication, possibly restricting treatment options.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1994.04a
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• pp.195-195
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• 1994

병원별 총 추적기간은 602-4,137 인년 이었으며, 병원별 대상자 1인당 추적일수의 중앙값은 34.5-61일 이었다. 병원별 추적 완료율도 35.3-92.3%로 다양하게 나타났다. 대상자중 칼슘차단제의 혈관확장효과에 따른 부작용들의 8주간 누적 발생율을 보면, 안면홍조 23.3%, 두통 13.5%, 심계항진 13.3%, 어지러움 7.6%, 하지부종 6.6% 였다. 그 외 부작용으로는 변비 13예, 소화장애 8예, 오심 6예, 치은비대, 안면부종, 피로감이 각각 2예, 탈모증, 불면증, 허약감, 피부질환, 호흡곤란, 손발저림, 발한, 구강건조 등이 각각 1예 있었다. 안면홍조의 발생율이 남자(12.9%)보다 여자(29.9%)에서 높았으며, 투여한 약제에 따라서 Nitrendipine 34.0%, Nifedipine 26,6%, Nicardipine 17.8%, Amlodipine 12.2%로써 약제별로 차이가 있었다. 두통의 발생율은 40세 미만 32.8%, 40-54세 15,8%, 55세 이상 10.5%로써 연령이 증가할수록 발생율이 낮았다. 하지부종의 발생율도 남자(3.4%)보다 여자(8.6%)에서 높았으며, 투여한 약제에 따라서 Nitrendipine 15.2%, Nifedipine 10.0%, Amlodipine 2, 1%, Nicardipine 0%로써 약제별로 차이가 있었다. 안면홍조가 발생한 환자에서 약물을 계속 투여시 2주후에 63.5%, 4주후에 77.0% 6주후에 88.5%가 소실하여 최초 안면홍조가 발생한 환자중 11.5%에서만 증상이 남아있었다. 약물투여를 중단하게 된 사유는 안면홍조와 두통이 각각 15예, 심계항진 4예, 어지러움 2예, 변비 및 안면부종이 각각 1예로 나타났다.

• Journal of dental hygiene science
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• v.16 no.5
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• pp.370-377
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• 2016

This study is conducted to provide a basis for effective management of bad breath with a poll in 155-scaling patients visiting the dental hygiene department of a university located in Gyeong-gi province after grasping the relevance among halitosis, xerostomia, and stress from them. Analysis was performed using PASW Statistics 18.0. The results of the halitosis measurements based on the general properties showed a significant difference in the hydrogen sulfide ($H_2S$) level depending on the patient's age; the highest level of 355.61 was observed in patients in their twenties followed by 227.85 in the fifties (p<0.001). The level was higher in cases with sinusitis or rhinitis (p=0.034). The $H_2S$ and $(CH_3)_2S$ levels showed are levant (r=0.492, p<0.01) correlation with the components of halitosis. Further, among other factors affecting breath odor, $(CH_3)_2S$ was shown to increase with increased stress. These results indicate that emotional factors, such as stress, should be considered when diagnosing patients with halitosis, and systematic and standardized diagnostic tools should be developed.

• Journal of Korean society of Dental Hygiene
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• v.15 no.1
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• pp.55-62
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• 2015

Objectives: The purpose of this study was to investigate the associated factors of self-reported dry mouth in adults. Methods: A self-reported questionnaire was filled out by 249 adults in Seoul and Gyeonggi-do from June to October, 2014. The questionnaire consisted of general characteristics of the subjects, age, monthly income, smoking, alcohol drinking, and systemic diseases including systemic diseases, medication, oral health status, and stress. The question for dry mouth consisted of dryness in skin, eyes, lips, and nasal mucosa. The subjective dry mouth consisted of 6 questions measured by visual analogue scale(VAS). Cronbach's alpha was 0.881 in the study. Oral health related quality of life (OHIP-14) was adapted from Yoon. The questionnaire for OHIP-14 included functional limitation, physical pain, psychological disability, social disability, and experience in hadicap measured by Likert 5 scale. Cronbach's alpha was 0.885 in the study. Data was analyzed for a t-test, one-way ANOVA and multiple regression analysis by using SPSS(SPSS 18.0, USA) program. Results: There were positive correlations between oral health-related quality of life and self-reported dry mouth (functional limitation r=0.288, physical pain r=0.219, psychological discomfort r=0.193, physical disability r=0.280, psychological disability r=0.205, social disability r=0.224 and handicap r=0.270). In the multiple regression analysis, variation of self-reported dry mouth were positively associated with dry eyes{very often(${\beta}=0.305$)), sometimes(${\beta}=0.186$)}, dryness on lips{very often(${\beta}=0.247$), sometimes(${\beta}=0.177$)}, handicap(${\beta}=0.152$), physical disability(${\beta}=0.128$) and alcohol drinking(1-2 times/week)(${\beta}=0.116$) (p<0.001). Conclusions: Self-reported dry mouth may cause deterioration of the entire body dryness(dryness on eyes and lips), low oral health-related quality of life(handicap and physical disability) and alcohol drinking. Thus, It is necessary to develop oral health education programs to prevent and manage dry mouth in adults.

• Journal of Oral Medicine and Pain
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• v.38 no.2
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• pp.137-142
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• 2013

Oral Medicine includes temporomandibular disorder, orofacial pains such as neuropathic pain, soft tissue diseases, halitosis, laser treatment, snoring, sleep apnea and identification through forensic dentistry etc. Such diseases are relatively common and cause great inconvenience and pain to the patients, as well as incur fatal health scare at times. In terms of oral medicine, the number of orofacial patients is growing due to a change in the life style and an increased stress as time goes in contemporary society and the demand of areas requiring oral medical professionalism, such as soft tissue lesions, snoring and sleep apnea, forensic dentistry evaluation and others are rapidly ascending. Consequently, among the areas in dental science, the calls for the expertism in oral medicine and its role are mounting. Analyzing the distribution according to disease entity, symptoms, duration of disease, and the prehistory courses of new patients visiting the department of oral medicine in a year provides information of the role and the relative importance of oral medicine in prospect and enables effective diagnosis and treatments for the patients. Therefore, in the present study, by analyzing new patients visiting the oral medicine clinic in our dental hospital for a year and by evaluating the role and the professionalism in future oral medicine, the authors concluded the followings: 1. It was founded that new patients to oral medicine mainly had temporomandibular disorders, soft tissue diseases, and neuropathic pains. 2. The number of patients with temporomandibular disorder appeared to be the highest percentage and the order within this was the patients with combined disorders, muscle disorder, and internal derangement of joint disc. 3. The number of patients with xerostomia appeared to be the highest percentage within soft tissue disease, followed by lichen planus and recurrent apthous ulcers. 4. The number of patients with burning mouth syndrome appeared to be the highest percentage within neuropathic pain.

• Journal of Korean Clinical Health Science
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• v.6 no.2
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• pp.1156-1170
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• 2018

Purpose. This study was conducted to analyze fatigue and subjective oral health status in the employees in educational institutions and provide basic data for the development of a program for the promotion of oral health. Methods. As for the subjects, this study conducted a survey with 468 educational personnel in elementary, middle, and high schools in the Daegu-Gyeongbuk area from March through June 2016 and utilized 407 copies finally. As for the items on the survey, this study conducted an investigation on their general characteristics, fatigue, and subjective oral health status(halitosis, xerostomia, temporomandibular disorder) with the self-administered method. With the data collected, this study conducted frequency analysis, t-test, ANOVA, and multiple regression analysis, using SPSS 20.0 statistical program, and the statistical significance level was .05. Results. As a result of this study, it turned out that by sex, fatigue was higher in women(4.59 points); by the place of work, those in 'elementary school' had higher fatigue(4.59 points); and by health condition and oral health status, most of them responded that they were 'not healthy'(4.81 and 4.84 points, respectively) and there was a statistically significant difference (p<.05). As for the correlation between fatigue and subjective oral health status, there were positive(+) impacts on halitosis(=.248, p<.001), xerostomia(=.097, p<.05), and temporomandibular disorder(=.148, p<.01), so it turned out that there was a correlation between fatigue and subjective oral health status. Conclusion. Based on the result of an analysis of the impacts of the fatigue level on subjective oral health status, it is judged that it would be necessary to continue to build up a program that can promote the oral health status of the educational personnel. In addition, it is necessary to conduct studies continuously for the development and application of a program for the change in lifestyle and behavior that can lower their fatigue.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.37 no.1
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• pp.69-85
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• 2024

Objectives : By analyzing articles on xerostomia and burning mouth syndrome, two representative diseases that cause various symptoms in oral cavity. Methods : We analyzed articles by dividing them into review articles, original articles, case reports. The subjects were 11 articles on xerostomia and 13 articles on burning mouth syndrome published in Korean medical journals. Results : 1. The subjects were 11 articles on xerostomia and 13 articles on burning mouth syndrome published in Korean medical journals. 2. The first article was published in 2007 and the most published articles were three each in 2013, 2018 and 2022. 3. Classification by type of article was as follows: 2 review articles(8.3%), 16 original articles(66.7%) and 6 case reports(25.0%). 4. The journal with the most published articles was journal of internal Korean medicine and the topics were xerostomia(72.7%), burning mouth syndrome(76.9%). 5. For both diseases, the number of female patients was higher than that of male patients. 6. The main symptom of xerostomia is dryness in the mouth and the main symptom of burning mouth syndrome is pain in the oral cavity. 7. Questionnaires, diagnosis based on dialectics and diagnostic devices were used to diagnose xerostomia and burning mouth syndrome. Conclusion : Diagnosis of xerostomia and burning mouth syndrome require overall consideration the entire hum an body along with the oral cavity. Since there are many different diagnostic methods, appropriate methods must be carefully selected and used.

• Journal of Hospice and Palliative Care
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• v.16 no.4
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• pp.205-215
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• 2013

Most terminally ill cancer patients experience various physical and psychological symptoms during their illness. In addition to pain, they commonly suffer from fatigue, anorexia-cachexia syndrome, nausea, vomiting and dyspnea. In this paper, I reviewed some of the common non-pain symptoms in terminally ill cancer patients, based on the National Comprehensive Cancer Network (NCCN) guidelines to better understand and treat cancer patients. Cancer-related fatigue (CRF) is a common symptom in terminally ill cancer patients. There are reversible causes of fatigue, which include anemia, sleep disturbance, malnutrition, pain, depression and anxiety, medical comorbidities, hyperthyroidism and hypogonadism. Energy conservation and education are recommended as central management for CRF. Corticosteroid and psychostimulants can be used as well. The anorexia and cachexia syndrome has reversible causes and should be managed. It includes stomatitis, constipation and uncontrolled severe symptoms such as pain or dyspnea, delirium, nausea/vomiting, depression and gastroparesis. To manage the syndrome, it is important to provide emotional support and inform the patient and family of the natural history of the disease. Megesteol acetate, dronabinol and corticosteroid can be helpful. Nausea and vomiting will occur by potentially reversible causes including drug consumption, uremia, infection, anxiety, constipation, gastric irritation and proximal gastrointestinal obstruction. Metoclopramide, haloperidol, olanzapine and ondansetron can be used to manage nausea and vomiting. Dyspnea is common even in terminally ill cancer patients without lung disease. Opioids are effective for symptomatic management of dyspnea. To improve the quality of life for terminally ill cancer patients, we should try to ameliorate these symptoms by paying more attention to patients and understanding of management principles.

• The Journal of Korean Medicine
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• v.34 no.3
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• pp.13-24
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• 2013

Objectives: The aims of this study were to investigate the availability of diagnosis of Yin-deficiency in the elderly with xerostomia and factors influencing subjective oral dryness. Methods: We surveyed 50 patients recruited by the clinical trial, 'Efficacy of Yukmijihwang-tang on Xerostomia in the Elderly: A Randomized, Double-blind, Placebo-controlled, Two-center Trial'. The subjects were assessed on their subjective oral dryness using the Dry Mouth Symptom Questionnaire (DMSQ). Their salivary functions were measured by Unstimulated Salivary Flow Rate (USFR) measurements. In addition, the subjects were evaluated on their Qi-stagnation and Yin-deficiency conditions using the Qi-stagnation questionnaire and Yin-deficiency questionnaire. Results: There were statistically significant correlations between three variables (USFR, DMSQ score and Qi-stagnation score) and Yin-deficiency score. In the multiple regression analysis, the regression model was statistically significant (F = 10.273, p < .001). The factor most strongly influencing the subjective oral dryness was USFR (${\beta}$ = -0.386). Yin-deficiency had the next strongest impact on the subjective oral dryness (${\beta}$ = 0.371). Qi-stagnation affected the subjective oral dryness weakly (${\beta}$ = 0.075). In the simple regression analysis, Yin-deficiency had a statistically significant effect on each of six subscales of DMSQ (p < .01). Among the six subscales, DMSQ-1 ('Oral dryness at night or on awakening') was the most strongly influenced by Yin-deficiency. Conclusions: The results of this study show that the diagnosis of Yin-deficiency in the elderly with xerostomia was available and Yin-deficiency was an important factor influencing the subjective oral dryness. Therefore, the consideration of Yin-deficiency is significant for diagnosis and treatment in the elderly with xerostomia.

• Journal of Welding and Joining
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• v.15 no.6
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• pp.24-31
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• 1997

2매의 금속을 맞대어 그 한 쪽에 접촉면과 평행하게 고주파진동을 가하면 단 시간에 접합된다. 이공정을 초음파 용접이라고 하며 그 물리적인 본질은 아직 불분명 하지만, 첫째로는 강한 마찰에 의해 금속 자유면의 산화물층이 제거되기 때문이라는 점과 둘째로는 마찰에 의해 금속 표면이 강하게 가열되어 이에 따른 연화에 의해 접합 이 된다고 하는 점이다. 그러나 이와 같이 가열된다고 하더라도 가열은 표면부에만 국한되고 다른 부분은 가열되지 않는다. 따라서 초음파용접은 냉간접합이라고도 한다. 또 가압력과 진동에 의한 힘이 동시에 작용하기 때문에 용접할 면을 미리 청정하게 할 필요는 없고 용접전의 단계에서 자연적으로 청정화가 이루어진다고 하는 사실이 간접 적으로 증명되고 있다. 초음파 용접(Ultrasonic welding)의 특징을 요약하면 고상용접 의 일종으로서 용접중에 국부적으로 고주파 진동에너지와 압력을 가하여 용접하는 방법이다. 이 때 모재를 용융시키지 않고 건전한 야금학적 결합부가 얻어진다는 데에 큰 특징이 있다. 또한 초음파용접은 다른 용접법에 비해 경제성이 매우 높고, 초음파 용접에 필요한 출력이 전기아크 용접에 필요한 출력의 5 - 10%로 충분한 경우가 많다. 초음파 용접은 통상의 방법으로는 용접하기 어려운 동종 금속이나 이종 금속의 용접에 널리 사용된다. 이 용접법은 반도체, 미세회로, 전기 접점의 형성에 대한 생산기술 로서 사용되고 있는데 소형 모터, 알루미늄 박의 가공, 알루미늄 합금의 조립 등에 이용되고 있다. 한편 최근에는 자동차, 우주항공산업 분야의 구조제 용접용으로도 채용되고 있다.출함이 바람직하다.분비되는 배설-분비 항원의 자극과 깊은 관계가 있음을 알 수 있었다.넌트 명세서를 대한 XML DTD(Document Type Definition)를 정의하고, HTML 기반 검색 방법과 XML 기반 검색 방법에 대한 컴포넌트 검색 성능을 비교한다.따라 NO 생산 및 세포독성이 증가하였고. NO 생산을 저하시키는 약제들은 활성화된 복강 대식세포 및 RAW264.7 세포에 의한 질편모충에 대한 세포독성을 현저히 감소시키는 것으로 보아 NO는 질편모충에 대한 대식세포의 숙주 방어기전에서 중요한 역할을 감당할 것으로 생각된다.nction index) 와 최대개구시 동통의 정도는 시술전과 시술 4주후간에 유의한 차이가 관찰되었다.피부온도는 검사자간에는 특정부위에 따라 다소 차이가 있을 수 있으나 일반적으로 높은 재현성을 보여줌으로서 향후 교근 및 측두근의 임상연구 평가에 피부온도조사는 도움이 되리라 사료된다. lactobacilli의 양은 peroxidase system을 함유하거나(p < 0.01) 함유하지 않은(p < 0.05) 치약을 사용한 군 모두에서 양치전에 비해 유의성있게 감소하였다. 6. 양치후 30분에 채취한 구강건조증 환자의 자극성 전타액내 S. mutans 양은 peroxida system을 함유한 세치제를 사용한 군에서 대조군에 비해 유의성있게 낮았다(p < 0.05). 7. 양치후 30분에 채취한 구강건조증 환자의 자극성 전타액내 lactobacilli양은 peroxidase system을 함유한 세치제를 사용한 군에서 대조군에 비해 상대적으로 낮게 나타났으나(p = 0.067)