• The Journal of the Korea Contents Association
• /
• v.20 no.12
• /
• pp.454-459
• /
• 2020

The main cause of oral disease is the formation of tooth surface bacteria, and a chemical mouthwash is used as a suppression method. However, chemical preparations have side effects, so we tried to verify the antibacterial effect of bamboo extract against oral microbes. Subjects were 15 college students as a control group and an experimental group, and the changes in oral microbes before and after the use of distilled water and bamboo extract were compared. Analysis of SPSS Windows ver. 20.0 was used (p<0.05). Results The total number of pathogenic microorganisms further decreased after using bamboo extract solution after using gargling solution between groups.

• Journal of the Korea Convergence Society
• /
• v.10 no.12
• /
• pp.109-115
• /
• 2019

This study was conducted to identify the relationship among the cognitive function of the elderly with dementia in the nursing home and the oral health condition and pathogenic microorganisms in the mouth. Data was collected for a month in February 2019 for 30 people through a non-probable sampling method due to the special nature of dementia elderly people aged 70 years or older, living in nursing homes in Daegu. Technical statistics, ANOVA, and Pearson's correlation coefficient were analyzed using the SPSS window ver. 21.0 program. According to the study, the lower the rating of long - term care classification in nursing homes, the more the number of high-risk oral pathogens, and the more the number of existing permanent teeth, the more the number of microbes in the mouth. However, there was no significant difference in cognitive function. Therefore, it is suggested that oral health care, an elderly dementia people in nursing homes, should have different management methods depending on the oral environment, and also professional managers should be able to manage oral health condition for actual care.

• Korean Journal of Microbiology
• /
• v.55 no.1
• /
• pp.52-54
• /
• 2019

Dialister pneumosintes is a Gram-staining-negative, anaerobic, non-fermenting, and rod-shaped bacterium. D. pneumosintes is considered to be a periodontal pathogen. D. pneumosintes KCOM 1685 (= ChDC B414) was isolated from a human postoperative maxillary cyst lesion. In this report, we present the draft genome sequence of D. pneumosintes KCOM 1685.

• Journal of Korean society of Dental Hygiene
• /
• v.22 no.5
• /
• pp.411-416
• /
• 2022

Objectives: This study aimed to identify pathogenic microorganisms in the oral cavity of Alzheimer's dementia patients and recognize the necessity and importance of oral prevention management. Methods: The participants comprised 40 dementia patients aged 60 years or older and general patients who were using nursing care facilities in Gwangju from February to July 2017. Samples were collected with Eazyperio products for oral pathogenic microbial testing. Eighteen types of bacteria could be detected by analyzing Multiplex-Quantity Real Time polymerase chain reaction at a genetic testing agency. Results: The study comprised more women than men. Most participants were in their 80s. Statistically significant differences were observed in some oral pathogenic microorganisms. Conclusions: Pathogenic microorganisms could more easily proliferate in the oral cavities of Alzheimer's dementia patients than they could among general elderly participants due to a lack of awareness of oral hygiene and prevention management. To improve this, it is considered necessary to deploy oral health care professionals.

• Journal of Life Science
• /
• v.31 no.1
• /
• pp.100-108
• /
• 2021

In the oral cavity, there are hundreds of microbial species that exist as planktonic cells or are incorporated into biofilms. The accumulation and proliferation of pathogenic bacteria in the oral biofilm can lead to caries and periodontitis, which are typical oral diseases. The oral bacteria in the biofilm not only can resist environmental stress inside the oral cavity, but also have a 1,000 times higher resistance to antibiotics than planktonic cells by genes exchange through the interaction between cells in the oral biofilm. Therefore, if the formation of oral biofilm is suppressed or removed, oral diseases caused by bacterial infection can be more effectively prevented or treated. In particular, since oral biofilms have the characteristic of forming a biofilm by gathering several bacteria, quorum sensing, a signaling system between cells, can be a target for controlling the oral biofilm. In addition, a method of inhibiting biofilm formation by using arginine, an alkali-producing substrate of oral bacteria, is used to convert the distribution of oral microorganisms into an environment similar to that of healthy teeth or inhibit the secretion of glucosyltransferase by S. mutans to inhibit the formation of non-soluble glucans. It can be a target to control oral biofilm. This method of inhibiting or removing the oral biofilm formation rather than inducing the death of pathogenic bacteria in the oral cavity will be a new strategy that can selectively prevent or therapeutic avenues for oral diseases including dental caries.

• Korean Journal of Microbiology
• /
• v.55 no.2
• /
• pp.154-156
• /
• 2019

Eikenella corrodens is Gram-negative, facultatively anaerobic, and rod-shaped bacterium. It is a part of the normal human mucosal flora that can cause several systemic diseases such as endocarditis, liver abscess, and intracranial bacterial infection. E. corrodens KCOM 3110 (= JS217) was isolated from human subgingival dental plaque of periodontitis lesion. Here, we present the complete genome sequence of E. corrodens KCOM 3110.

• Journal of the korean academy of Pediatric Dentistry
• /
• v.50 no.2
• /
• pp.131-141
• /
• 2023

Dental caries is a multifactorial disease influenced by interactions between teeth, biofilm, dietary factors, and various biological, behavioral, sociocultural, and genetic factors. Recent research has shown that dental caries results from dysbiosis, an imbalance in the oral microbial community, shifting the concept from an infectious disease to a non-communicable disease (NCD). Dental caries shares similarities with other chronic NCDs such as cardiovascular diseases and diabetes, as they all relate to dietary intake, lifestyle habits, and environmental factors. Considering the high prevalence of dental caries and its impact on people's health and quality of life, it is important to understand dental caries as an NCD and develop effective oral health management strategies. Ecological prevention methods and efficient public health policies should be provided to reduce risk factors associated with dental caries.

• Journal of Oral Medicine and Pain
• /
• v.20 no.2
• /
• pp.283-289
• /
• 1995

레이저가 의학영역에서 사용된 후 구강내 연조직과 경조직 병소에 대한 임상적 적용에 관한 관심이 커져왔다. 레이저가 조사되는 부위에서는 대부분 연기가 발생한다. 이 경우 병원체가 존재하는 병소에 대한 레이저치료시 발생되는 연기속에 병원체가 포함되어 이Tekas 환자와 술자는 이의 흡입가능성이 크므로 균혈증 및 상기도나 호흡계의 의원성 감염이 유발될 수 있다. 저자는 레이저치료시 발생되는 연기속에 병원체가 포함되어 있는지의 여부를 규명하기위해 각각 10개의 실험군에 통기성 미생물인 Escherichia coli(E.coli)가 배양된 brain geart infusion (BHI) 배지와 E.coli 가 존재하는 치근단 병소를 실험적으로 만든 후 각각 pulsed Nd:YAG 레이저를 조사해 연기를 채취, 배양, 분석하여 다음과 같은 결과를 얻었다. 1. Pulsed Nd:YAG 레이저를 E. colir 배양된 agar substrate 와 실험적으로 만들어진 치근단부위의 E.coli 현탁액에 조사시 발생된 연기에서 처음 접종된 것과 같은 E.coli가 검출되었다. 2. 감염병소에 pulsed Nd:YAG 레이저를 조사시 발생되는 연기의 유해효과로부터 환자와 술자 및 보조자의 보호를 위해 효과적인 흡입기를 사용이 권장된다.

• Journal of the Korea Convergence Society
• /
• v.13 no.4
• /
• pp.653-657
• /
• 2022

Oral disease causes a significant health and economic burden worldwide, significantly reducing people's quality of life. Dental caries, a representative oral disease, is caused by S. mutans. Oral pathogenic microorganisms contain lipopolysaccharide (LPS), which can cause an immune response and cause various oral diseases. The purpose of this study was to investigate the antioxidant and antibacterial effects of bamboo leaf extract (BLE) to control oral diseases. THP-1, oral fibroblasts, and S mutans culture medium were treated with bamboo leaf extract at different concentrations of 0-8% to conduct the experiment.. As a result, the antioxidant effect according to the BLE concentration was confirmed in mononuclear cell lines and oral fibroblasts. In addition, the antibacterial effect of S. mutans according to the BLE concentration was demonstrated. Therefore, BLE can be used for the prevention or treatment of oral diseases.

• Journal of Dental Rehabilitation and Applied Science
• /
• v.37 no.4
• /
• pp.294-300
• /
• 2021

Necrotizing periodontal disease caused by plaque bacteria is showed clinical findings including pseudo-membrane, interproximal necrosis of the affected area, pain on palpation and gingiva bleeding. Microbiological examination is showed that patients have fusospirochetal bacteria. Two patients who were provisionally diagnosed as necrotizing periodontal disease received nonsurgical periodontal treatments in conjunction with dressing using 3% hydrogen peroxide and local antibiotic delivery. Before and 3 - 5 days after initial treatment, the levels of periodontal bacteria in gingival crevicular fluid obtained using quantitative PCR were compared. After treatment, patients recovered normal gingiva. The number of periodontal diseases related bacterial species decreased from seven or eight to one. As a result, periodontium of patients with necrotizing periodontal disease was recovered to normal periodontium by nonsurgical periodontal treatments.