• Title/Summary/Keyword: 광치료

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Polarization-sensitive Optical Coherence Tomography Imaging of Pleural Reaction Caused by Talc in an ex vivo Rabbit Model (생체 외 토끼 모델에서의 탈크에 의해 유발되는 흉막 반응의 편광 민감 광 결맞음 단층촬영 이미징)

  • Park, Jung-Eun;Xin, Zhou;Oak, Chulho;Kim, Sungwon;Lee, Haeyoung;Park, Eun-Kee;Jung, Minjung;Kwon, Daa Young;Tang, Shuo;Ahn, Yeh-Chan
    • Korean Journal of Optics and Photonics
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    • v.31 no.1
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    • pp.1-6
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    • 2020
  • The chest wall, an organ directly affected by environmental particles through respiration, consists of ribs, a pleural layer and intercostal muscles. To diagnose early and treat disease in this body part, it is important to visualize the details of the chest wall, but the structure of the pleural layer cannot be seen by chest computed tomography or ultrasound. On the other hand, optical coherence tomography (OCT), with a high spatial resolution, is suited to observe pleural-layer response to talc, one of the fine materials. However, intensity-based OCT is weak in providing information to distinguish the detailed structure of the chest wall, and cannot distinguish the reaction of the pleural layer from the change in the muscle by the talc. Polarization-sensitive OCT (PS-OCT) takes advantage of the fact that specific tissues like muscle, which have optical birefringence, change the backscattered light's polarization state. Moreover, the birefringence of muscle associated with the arrangement of myofilaments indicates the muscle's condition, by measuring retardation change. The PS-OCT image is interpreted from three major perspectives for talc-exposure chest-wall imaging: a thickened pleural layer, a separation between pleural layer and muscle, and a phase-retardation measurement around lesions. In this paper, a rabbit chest wall after talc pleurodesis is investigated by PS-OCT. The PS-OCT images visualize the pleural layer and muscle, respectively, and this system shows different birefringence of normal and damaged lesions. Also, an analyisis based on phase-retardation slope supports results from the PS-OCT image and histology.

Short-Term Result of Endovenous 980-nm Diode Laser Treatment in Varicose Vein of Looter Extremities (하지정맥류에서 정맥내 980-nm 다이오드 레이저 치료의 단기결과)

  • Lee Seock Yeol;Song In Hag;Lee Seung Jin;Park Hyung Joo;Lee Cheol Sae;Lee Kihl Rho
    • Journal of Chest Surgery
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    • v.38 no.8 s.253
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    • pp.557-563
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    • 2005
  • Background: Recently 980-nm diode laser endovenous treatment was introduced and used as a method of treatment for varicose vein in lower extremities. The advantages of endovenous laser treatment are good cosmetic effects without incision and avoidance of complications associated with surgery. Therefore, we performed an endovenous laser treatment using a 980-nm diode laser and observed the effects and the efficiency of treatment. Material and Method: From October, 2003 to March, 2004, 55 patients (84 limbs) underwent endovenous laser treatment with a 980-nm diode laser. The effects of treatment, complications and recurrences were reviewed. Result The mean age of patients was 47.2 years old and the number of men and women were 2f and 35. In a total of 84 limbs, postoperative complications were transient ecchymosis(84 cases), local paresthesia (24 cases), local skin discolorization (6 cases), minimal burn (3 cases), and post operative phlebitis (1 cases). Adjuvant sclerotherapy was performed in 27 limbs and it was performed in varicose veins missed at operation and varicose veins remaining after endovenous laser treatment. In a total of 56 patients, 2 patients $(3.57\%)$ had recurrences after endovenous laser treatment and were treated with phlebectomy. Conclusion: Our findings demonstrated that 980-nm endovenous laser treatment had good cosmetic results with acceptable complications. This study was based on short-term results and long term follow-up is necessary to evaluate the accurate effects of treatment and recurrence. We think that multimodality treatment with endovenous laser treatment including phlebectomy or transilluminated powered phlebectomy can help decreasing of recurrence especially in patients with tortuous varicose cluster.

A Comparison of coincidence between the Light field & the Radiation field using film and BIS (필름과 BIS 영상장치를 이용한 광/방사선조사야 일치성 비교평가)

  • Bang, Dong-Wan;Seok, Jin-Yong;Jeong, Yun-Ju;Choi, Byeong-Don;Park, Jin-Hong
    • The Journal of Korean Society for Radiation Therapy
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    • v.16 no.2
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    • pp.33-41
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    • 2004
  • Purpose : Film has been the primary tool in coincidence testing between the light field and the radiation field, which constitutes the quality assurance list of a linear accelerator. But there is a great chance of errors being different among the observer when using film. Thus this study set out to use the BIS(Beam Image System) in addition to film in comparing and evaluating coincidence results between the two fields and in searching for the improvement measures. Materials & Methods : Photon beam of 6 and 15MV was exposed to film and the BIS using a linear accelerator. The light and radiation fields were each $50{\times}50,\;100{\times}100,\;and\;200{\times}200mm^2$. The gantry angle was $0^{\circ}$ when using film and $0^{\circ}\;and\;270^{\circ}$ when using the BIS. The devices adopted to test coincidence between the two fields were a ruler and film scanner when using film. With the BIS, the width of the scanned light and radiation fields was measured for errors with setting the X and Y axis. Results : The visual measurements of the observer with film resulted that the radiation field was bigger than the light field and that their maximum error was 1.9mm. The results were the same with the measurements using the film scanner except for the average error, which was less than 1.9mm. On the contrary, the measurements using the BIS showed that the light field was bigger than the radiation field at the gantry angle of $0^{\circ}\;and\;270^{\circ}$. The maximum error was 0.96mm, and the error range was $<{\pm}2mm$ both in the X and Y axis. The average error of ${\Delta}X$, Y was the smallest in the order of the visual film measurements, film scanner measurements, and BIS measurements Conclusion . This requires a careful measurement for accurate quality assurance since errors are much different according to each observer that tests coincidence between visual fields with film. And an observer needs to use another image device or develop a measuring device of his own if it seems necessary for accurate measurements.

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THE EFFECTS OF FLUORIDE RELEASING ORTHODONTIC SEALANT ON THE SHEAR BOND STRENGTH Of LIGHT-AND CHEMICAL-CURED ORTHODONTIC RESINS (불소가 유리되는 교정용 전색제가 광중합형 및 화학중합형 교정용 접착제의 전단결합강도에 미치는 영향)

  • Kim, Bong-Hyun;Yoon, Young-Jooh;Kim, Kwang-Won
    • The korean journal of orthodontics
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    • v.27 no.5 s.64
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    • pp.781-789
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    • 1997
  • The purpose of this study was to evaluate the effects of fluoride relasing orthodontic sealant on the shear bond strength of light-and chemical-cured orthodontic rosins, to compare the shear bond strenth with light-and chemical-cured orthodontic resins, and to identify the changes of shear bond strength by rebonding in vitro. The brackets were divided into eight groups. Each group of metal brackets had different bonding mechanisms with adhesives. Group A : Transbond only Group B : Mono-Lok 2 only Group C : Light cured FluoroBond+Transbond Group D : Light cured FluoroBond+Mono-Lok 2 Group E : Transbond only(rebonded) Group F : Nomo-Lok 2 only(rebonded) Group G : Light cured FluoroBond+Transbond(rebonded) Group H : Light cured FluoroBond+Mono-Lok 2(rebonded) 65 extracted human premolars were prepared for bonding and 65 metal brackets for each group were bonded to prepared enamel surfaces of buccal surfaces as the above prescription. 24 hours bonding after, the Instron universal testing machine was used to test the shear bond strength of metal brackets to enamel. After debonding, same kind of metal brackets for each group were rebonded to prepared enamel surfaces of buccal surfaces to test the shear bond strength at the rebonding to enamel. Statistical analysis of the data was carried out Student's t-test ANOVA test, and Scheffe test using $SPSS/PC^+$ The results were as follows : 1. The order of shear bond strength was Group B(11.84MPa), Group A(10.75MPa), Group, D(9.69MPa), and Group C(9.39MPa)in lst bonded groups. 2. The order of shear bond strength was Group E(7.40MPa), Group G(6.48MPa), Group F(5.89MPa), and Group H(5.15MPa) in rebonded groups. 3. The shear bond strength of chemical cured orthodontic rosins had higher than that of light-cured orthodontic resins in all groups, but there was no statistical significance between groups(P>0.05). 4. In rebonded groups, the shear bond strength of light cured orthodontic rosins had higher than that of chemical cured orthodontic resins, but there was no statistical significance between groups(P>0.05). 5. The shear bond strength of all rebonded groups progressively decreased than that of 1st bonded groups, and there was statistical significance between groups(p<0.05, p<0.001).

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A photoelastic study of the stress distribution on canine retraction by segmented TMA T-loop spring (Segmented TMA T-loop spring에 의한 견치 후방이동시의 응력분포에 관한 광탄성법적 분석)

  • Yoon, Young-Jooh;Kim, Kwang-Won;Yu, Pil-Sik
    • The korean journal of orthodontics
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    • v.31 no.2 s.85
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    • pp.199-207
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    • 2001
  • The segmented TMA T-loop spring, used for reciprocal space closure and described by Burstone, was used to achievebodily movement of canine. Photoelastic analysis is a technique for the transformation of internal stress into visible light patterns. The two-dimensional photoelastic stress analysis was performed, and stress distribution was recorded by photography. The purpose of this study was to visualize photoelastically the distribution of forces transmitted to the alveolus and surrounding structures using new segmented TMA T-loop spring for canine retraction. The results were as follows: 1. Decreased activation produced decreased stress of upper 1st. premolar extraction site and increased intrusive stress of upper 1st. molar, regardless of T-loop position. 2. At 5mm activation, More posterior positioning of T-loop Produced an increased stress in upper 1st. premolar extraction site. 3. At 3mm activation, More posterior positioning of T-loop produced an increased stress in upper 1st. premolar extraction site and mesial lower half of upper 1st. molar mesio-buccal root. 4. At 1mm activation, More anterior positioning of T-loop produced an increased stress in upper mesial and blew apex area of upper canine root. 5. 0.25 B/L ratio and 3mm activation produced bodily movement of canine. To summarize, desired tooth movement and anchorage requirement is possible by altering the activation and mesio-distal position of the T-loop spring.

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Early caries detection using optical coherence tomography: a review of the literature (광간섭단층촬영술을 이용한 치아우식증의 발견)

  • Park, Young-Seok;Cho, Byeong-Hoon;Lee, Seung-Pyo;Shon, Won-Jun
    • Restorative Dentistry and Endodontics
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    • v.36 no.5
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    • pp.367-376
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    • 2011
  • Early detection of carious lesions increases the possibility of treatment without the need for surgical intervention. Optical coherence tomography (OCT) is an emerging three-dimensional imaging technique that has been successfully used in other medical fields, such as ophthalmology for optical biopsy, and is a prospective candidate for early caries detection. The technique is based on low coherence interferometry and is advantageous in that it is non-invasive, does not use ionizing radiation, and can render threedimensional images. A brief history of the development of this technique and its principles are discussed in this paper. There have been numerous studies on caries detection, which were mostly in vitro or ex vivo experiments. Through these studies, the feasibility of OCT for caries detection was confirmed. However, further research should be performed, including in vivo studies of OCT applications, in order to prove the clinical usefulness of this technique. In addition, some technological problems must be resolved in the near future to allow for the use of OCT in everyday practice.

Enhanced biosynthesis of artemisinin by environmental stresses in Artemisia annua (환경스트레스 처리에 의한 개똥쑥 artemisinin 생합성 증진)

  • Kyung Woon Kim;Cheol Ho Hwang
    • Journal of Plant Biotechnology
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    • v.49 no.4
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    • pp.307-315
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    • 2022
  • Artemisinin is a secondary metabolite of Artemisia annua that shows potent anti-malarial, anti-bacterial, antiviral, and anti-tumor effects. The supply of artemisinin depends on its content in Artemisia annua, in which various environmental factors can affect the plant's biosynthetic yield. In this study, the effects of different light-emitting diode (LED)-irradiation conditions were tested to optimize the germination and growth of Artemisia annua for the enhanced production of artemisinin. Specifically, the ratio between the red and blue lights in the irradiating LED was varied for investigation as follows: [Red : Blue] = [6 : 4], [7 : 3], and [8 : 2]. Furthermore, additional stress factors like UV-B-irradiation (1,395 ㎼/cm2), low temperature (4℃), and dehydration were also explored to induce hormetic expressions of ADS, CYP, and ALDH1, which are essential genes for the biosynthesis of artemisinin. Quantitative polymerase chain reaction (qPCR) was used to analyze the expression levels of the respective genes and their correlation with the specified conditions. [8 : 2] LED-irradiation was the most optimal among the tested conditions for the cultivation of Artemisia annua in terms of both fresh and dry weights post-harvest. For the production of artemisinin, however, [7 : 3] LED-irradiation with dehydration for six hours pre-harvest was the most optimal condition by inducing around twofold enhancement in the biosynthetic yield of artemisinin. As expected, a correlation was observed between the expression levels of the genes and the contents of artemisinin accumulated.

Surgical Treatment of Thoracic Injuries Combined with Abdominal Injuries (복부 손상을 동반한 흉부손상 환자의 외과적 치료)

  • Jeong, Seong-Un;Kim, Byeong-Jun;Lee, Seong-Gwang
    • Journal of Chest Surgery
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    • v.28 no.9
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    • pp.842-846
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    • 1995
  • Recently, the trauma patients have been markedly increasing due to the vast increase of traffic accident, industrial disaster, incidental accident and violence. The authors have analysed of 22 patients of thoracic injuries combined with abdominal injuries and summarized as follows. The ratio of male to female was 3.4:1 and their age distribution was from 5 years to 68 years and mean age was 34.4 years. The etiologies of injury were traffic accident, stab wound, fall down and violence. Associated injuries were fractures, bowel perforation, kidney rupture, head injury, liver laceration, spleen rupture and so forth. The modes of treatment were closed thoracostomy, repair of diaphragm, ruptured bowel repair, explo-thoracotomy, splenectomy, hepatic lobectomy in this order of frequency. The postoperative complications were atelectasis, wound infection, pneumonia, empyema, acute renal failure, respiratory failure and bleeding. The mortality rate was 13.6% [3/22 and the causes of death were respiratory failure 1 case, acute renal failure 1 case and hypovolemic shock 1 case.

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생체 신호 처리용 칩 기술 동향

  • Lim, Shin-Il
    • Review of KIISC
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    • v.17 no.1
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    • pp.38-46
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    • 2007
  • 유비쿼터스 네트워크(u-network)를 통해 u-health의 개념이 실현됨에 있어 생체 신호를 최초로 측정, 처리하는 부분의 생체 신호 측정용 칩들에 대한 최근 기술 개발 동향을 기술하였다. 이러한 추세에 맞추어 여러 가지 핵심 기술들이 부상하고 있지만, 본 기고에서는 이러한 시스템의 최종 하위 계층, 즉 단말기 등의 부분에 적용되는 bio 관련 시스템 반도체 칩(SoC : system-on-a-chip)에 대해 기술한다. 바이오 칩 중, 기존의 광을 사용하지 않고 값 싸게 구현 할 수 있는 CMOS 기반의 DNA 칩 개발 동향을 살펴보았으며, 신약 개발이나 치료에 사용할 수 있도록 신경 신호 전달을 검출할 수 있는 신경 신호 전달 측정 칩들의 기술 개발도 살펴보았다. 개인의 의료 생체정보를 모니터링 할 수 있도록 심전도, 근전도, 뇌파, 산소포화도, 체지방 등을 측정할 수 있는 의료용 칩들의 개발 현황도 살펴보았다.

Calcaneal Fractures-Extended Lateral Approach (종골 골절의 치료-광범위 외측 접근법)

  • Chun, Sung-Kwang;Kim, Hak Jun
    • Journal of Korean Foot and Ankle Society
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    • v.17 no.2
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    • pp.79-83
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    • 2013
  • Calcaneus is largest tarsal bone and the fracture of calcaneus is most common tarsal fractures. Calcaneal fractures are divided into extra-articular and intra-articular fractures. Intra-articular calcaneal fractures could be classified as tongue type and joint depression type using simple lateral radiograph (Essex-Lopresti classification), but Sanders suggested new classification according to involving the posterior facet of calcaneus using computed tomography. The involvement of posterior facet was revealed as more complicated than Essex-Lopresti classification. The principle purpose of treatment of calcaneal fractures are restoration of calcaneal height (B$\ddot{o}$hler angle), width, axis, anatomical reduction of joint and restoration of function through the stable fixation. Good visualization of joint and anatomical reduction could be achieved by extended lateral approach. But, skin problem could be occurred after of extended lateral approach.