• Clinical and Experimental Pediatrics
• /
• v.49 no.12
• /
• pp.1296-1300
• /
• 2006

Purpose : We studied the usefulness of transcutaneous bilirubinometers in follow-up of bilirubin levels during phototherapy in neonatal jaundice patients. Methods : Transcutaneous bilirubin (TcB) was measured twice per day on 90 neonatal jaundice patients without risk factors of jaundice by transcutaneous bilirubinometer JM-103(Minolta/Hill-Rom Air-shields, Japan). TcB was measured simultaneously on the patched-forehead (TcB-PF), patchedchest(TcB-PC), unpatched-forehead (TcB-UF) and unpatched-chest (TcB-UC) of infants with neonatal jaundice. Plasma bilirubin (PB) was measured by American Optical bilirubinometer (American Optical Co, Buffalo, USA) within 30 minutes after transcutaneous bilirubinometer measurement. Each TcB was compared with PB. Results : In the study group, the mean gestational age was $38.6{\pm}1.3wk$, the mean birthweight was $3,207.0{\pm}472.1g$, the mean age at start of phototherapy was $4.9{\pm}0.9days$ and the mean duration of phototherapy was $1.3{\pm}0.6days$. The correlation between TcB and PB level was observed. The correlation between TcB of the patched part (TcB-PF, TcB-PC) and PB was more significant than that of the unpatched part (TcB-UF, TcB-UC) and PB. The most significant correlation was between PB and TcB-PC. Conclusion : TcB was useful in the follow-up of jaundice during phototherapy as well the screening of jaundice in neonatal jaundice patients. TcB of patched-chest area was the most reliable site in transcutaneous bilirubinometer examination in neonatal jaundice patients.

• Journal of the Korean Applied Science and Technology
• /
• v.39 no.4
• /
• pp.552-559
• /
• 2022

Atopic dermatitis (AD) is a chronic inflammatory skin disease accompanied by severe itching, mainly before five. The aim of this study is to investigate the effects of 405 nm+850 nm LED light therapy on AD-like symptoms in NC/Nga mice. The mice were randomly placed in the normal (Vehicle), atopic dermatitis-induced (CON), and 405 nm + 850 nm LED light therapy (LED) groups. The LED experimental group conducted 405 nm+850 nm wavelength LED ray therapy for 10 minutes a day for seven days. LED light therapy research confirmed the improvement and improvement of Dermatics score and observed the reduction of epidermal tissue thickness caused by dermatitis. Based on the significant decrease of serum IL-1𝛽 and transdermal moisture loss and serum IgE concentration due to LED light therapy, LED light therapy can help restore normal skin conditions in mice that cause atopic dermatitis. This study showed the anti-atopic effect of infrared light and blue light. Light in mice with atopic dermatitis led to the simultaneous use of circular LEDs with two wavelengths.

• Journal of Yeungnam Medical Science
• /
• v.12 no.1
• /
• pp.75-83
• /
• 1995

Even though phototherapy is an effective means of treating hyperbilirubinemia, adequate binocular shields are essential to prevent light hazard of retina during phototherapy. The phototherapy to young albino rabbits was performed under various conditions; exposured for 12, 24, and 48 hours, continuity or intermittence of irradiation, and use of shields. Although there was no definite pathologic change in indirect ophthalmoscopic examination, severe damage was seen at electron microscopic level. In all experimental groups, swelling and edema of photoreceptor were seen at right after phototherapy. Futhermore, more severe damage was seen in case of intermittent irradiated group and prolong exposed group. In mydriatic eyes, severity of damage was similiar to non mydriatic eyes, but area of retinal damage was more extensive than non-mydriatic eyes. In control group which was protected by binocular shields during phototherapy, no significant abnormality was found.

• Electronics and Telecommunications Trends
• /
• v.25 no.5
• /
• pp.59-71
• /
• 2010

피부질환 치료를 위한 광선요법은 태양광, 레이저, 형광등, UV 램프 등 다양한 광원을 이용하여 광이 피부 내에서 생화학적 반응을 촉진하는 원리를 이용하여 피부 조직의 선택적 재생 또는 파괴 등을 통해 손상된 피부를 치료하는 광 의료 기술이다. 최근 발전하고 있는 LED 광원 기술은 광선요법에서 시용되어온 광원을 대체할 수 있는 기술로 각광을 받고 있다. 이에 본 고에서는 광선요법과 관련된 기초 원리를 살펴보고, LED가 피부질환 치료용 광원으로 사용될 때 고려되어야 하는 임상적, 기술적 문제점과 다양한 피부질환 치료에 있어서 LED 광원의 역할에 대해 살펴 보았다. 아울러, 피부질환 치료용 LED 치료기 관련 국내외 연구 개발 동향과 기업들이 출시한 LED 치료기의 특성을 살펴보았다. LED 치료기 관련 표준화 동향과 국내외 지식재산권 현황을 살펴보았으며, 향후 LED 기반의 피부질환 치료기의 개발 방향을 모색하였다.

• Sleep Medicine and Psychophysiology
• /
• v.1 no.2
• /
• pp.188-192
• /
• 1994

The author reports a 32 years old female patient with late luteal phase dysphoric disorder who received evening bright light treatment for 7 consecutive days during the late luteal phase of menstrual cycle. After the treatment, beneficial clinical effects were observed. This result suggests that bright light can be an alternative treatment for LLPDD. However, the placebo effects should be ruled out completely. Further controlled studies with more patients will be needed.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
• /
• 2001.05a
• /
• pp.215-218
• /
• 2001

본 연구는 가시광선영역에서 각각의 색을 구현하여 색채치료에 이용하기 위한 시스템을 개발하는데 있다. 사용된 광원은 에너지 밀도가 전파장에 걸쳐서 일정한 Dichroic reflector hallogen lamp를 사용하였고, 광원에서 발생하는 적외선을 차단하기 위하여 IR filter를 사용하였다. 색채치료에 사용 가능한 순수한 파장의 색을 분리하기 위하여 long pass filter와 short pass filter로 구성되는 color filter set를 사용하여 구성하였다. 개발된 가시광선 제시 시스템은 빨강, 파랑, 노란 광을 낼 수 있도록 되어 있으며 각각의 광도는 2390 lx, 1020 lx, 17400 lx이다. 개발된 시스템의 객관적 효과를 검증하기 위하여 피부 서식균으로 항균 실험을 하나 결과 노란 광이 빨강이나 파란 광에 비해 세포성장 억제가 컸다. 대식세포와 피부암세포로 실시한 항염 실험은 각각의 색광에 대한 영향이 크지 않았다.

• The Science & Technology
• /
• v.11 no.10 s.113
• /
• pp.57-58
• /
• 1978

태양광선이 강하게 내려 쬐이는 열대지방에 살고 있는 사람의 피부색이 검은 까닭은? ……이것이 인류가 오랜동안 진화하면서 자연환경에 적응한 것일까? 이에 대한 해결은 종래 여러 설이 있었다. 이에 대해 광에 약한 비타민류가 태양광선속의 자외선에 의해 광분해되는것을 막아주기 위함이란 견지에서 엽산염을 써서 시험관으로 실험하고 또 광선치료를 받은 백인이나. 열대주민의 비타민부족에 의한 산과영역의 이상들의 관찰로 이 설을 실증하는 연구가 미ㆍ미네소타대학 의학부의 브란트ㆍ잇튼 두 의학자에 의해 발표되었다.

• The Optical Journal
• /
• s.105
• /
• pp.27-29
• /
• 2006

레이저 광선이 가져다준 많은 장점과 편리함에 비하면 레이저의 위험성이라는 부정적인 요소가 차지하는 비중은 미미하다고 볼 수 있다. 그러나 우려되는 것은 레이저를 생산하거나 이용하는 공장의 작업장을 비롯하여, 수술 또는 치료용으로 사용하는 의료기관의 수가 지속적으로 늘어나고 있음을 감안할 때, 이러한 장소에서 레이저를 동작시키는 사용자를 포함한 주변사람이 레이저광선에 직접 또는 간접적으로 노출되어 사고를 당할 확률도 그만큼 높아지고 있다는 점이다.

• Physical Therapy Korea
• /
• v.3 no.1
• /
• pp.73-79
• /
• 1996

Photochemotherapy(UVA with 8-methoxypsoralen) was given to 30 patients with systemic psoriasis. The results of clearing and long-term(6-month) interval maintenance were reported. Clearing requirements were in general similar to these reported by Melski and Burger. The skin of the 14 patients (46.6%) recovered good skin condition by a once weekly maintenance dose. This result was better than that reported by other authors. 1. During initial treatment period, average number of treatment was 27.3 and average duration treatment was 24.8 weeks. 2. The factors to quit treatment were motion decrease, moving to the remote area, complications, etc. 3. Number of patient who received maintenance treatment was 14. 4. The complications reported from the patients were hyperpigmentation, nausea, headache, pruritis, vomiting, gastritis.

• Neonatal Medicine
• /
• v.17 no.2
• /
• pp.266-269
• /
• 2010

Gilbert's syndrome is caused by a reduction in the activity of uridine diphosphate glucuronosyltransferase (UGT) and induces chronic, non-hemolytic unconjugated hyperbilirubinemia. It has been suggested that 3-10% of the population has Gilbert's syndrome. Commonly, Gilbert's syndrome causes mild symptoms. However, a case of Gilbert's syndrome with severe neonatal hyperbilirubinemia is presented here. The patient developed jaundice three days after birth. Five days after birth, the patient's total serum bilirubin level was 34 mg/dL. The patient received intensive phototherapy and was given oral phenobarbital. Hemolytic hyperbilirubinemia was excluded on the basis of laboratory tests. Heterozygote polymorphisms of the promoter region (-3279T>G) and exon 1 (211G>A) were found in UGT1A1 gene. After discharge, the patient did not require any further treatment. This is the first case of proven Gilbert's syndrome with severe neonatal hyperbilirubinemia in Korea.