• Title/Summary/Keyword: 관찰-추천

Search Result 192, Processing Time 0.029 seconds

Changes of Polyamine Metabolism and Delayed Neuronal Degeneration of Hippocampus after Transient Cerebral Ischemia in Mongolian Gerbils (뇌허혈 손상에 있어서 Polyamine 대사의 변동이 해마신경세포의 지연성괴사에 미치는 효과에 관한 연구)

  • Shin, Kyung-Ho;Shin, Hwa-Jung;Lee, Young-Jae;Kim, Hyung-Gun;Choi, Sang-Hyun;Chun, Yeon-Sook;Chun, Boe-Gwun
    • The Korean Journal of Pharmacology
    • /
    • v.32 no.3
    • /
    • pp.323-334
    • /
    • 1996
  • Male Mongolian gerbils $(60{\sim}80g)$ were given DL-difluoromethylornithine (DFMO; 250mg/kg, ip) and methylglyoxal bis(guanylhydrazone) (MGBG; 50 mg/k, ip), respectively, 1 h prior to transient (7 min) occlusion of bilateral common carotid arteries (OBC7) and a daily dose of one of them for 6 days after recirculation, and the polyamine contents, activities of ornithine and S-adenosylmethionine decarboxylases (ODC and SAM-DC), and light microscopic findings of the hippocampus were evaluated. The hippocampal putrescine (PT) levels of the control gerbils treated with saline (STGr), markedly increased after OBC7, showing a peak level at 24 h after recirculation. The peak PT level was reduced in DFMO treated gerbils (DTCr) and in MGBG treated gerbils (MTGr). And 7 days after recirculation, the PT level of DTGr was decreased to about 75% of the PT level in the sham operated group (nonTGr) and to about 55% of the STGr level, respectively. The hippocampal spermidine (SD) level of STGr tended to decline, showing the lowest value at 8 h after recirculation. But the spermidine (SD) level of DTGr was somewhat higher at 8 h after OBC7 than those of STGr and MTGr The hippocampal spermine (SM) levels of all the experimental groups were little changed for 7 days after OBC. OBC7 markedly increased the hippocampal ODC activity. reaching a maximum (about 3 times higher than preischemic level) at 8 h and rapidly recovered to the control value by 24 h in STGr gerbils, and the OBC7-induced increase of ODC activity was significantly attenuated by DFMO or MGBG treatment. Whereas OBC7 induced a rapid decrease of the hippocampal SAMDC activity follwed by gradual recovery to the preischemic level, and the decrease of the SAMDC activity was slightly attenuated by DFMO or MGBG treatment. 7 Days after OBC7 the histological finding of the hippocampal complex stained with cresyl violet showed an extensive delayed neuronal damage in the CA1 region and to a lesser extent, in the dentate gyrus, sparing the CA3 region. And the neuronal death was aggevated by DFMO but significantly attenuated by MGBG. The immunochemical reactivity of hippocampus to anti-GFAP antibody was significantly increased in the CA1 region and to a lesser extent, in the dentate gyrus 7 days after OBC7, but was little changed in the CA3. And the increase of the anti-GFAP immunoreactivity was moderately enhanced by DFMO and significantly suppressed by MGBG. These results suggest that the polyamine metabolism may play a modulatory role in the ischemic brain damage.

  • PDF

Quality Characteristics of Jeung-Pyun with Tapioca Flour (타피오카 분말을 첨가한 증편의 품질특성)

  • Yoo, Chang-Hee;Shim, Young-Hyn
    • Korean journal of food and cookery science
    • /
    • v.22 no.3 s.93
    • /
    • pp.396-401
    • /
    • 2006
  • This study was performed to determine the quality characteristics of Jeung-Pyun with added tapioca flour. With increasing tapioca flour content, the moisture content of the product was decreased. The addition of tapioca flour increased the volume and symmetry compared to the control with no tapioca flour. The highest uniformity was shown by the 10% added group, but the differences were not significant. In the Hunter's value, the lightness of the control was higher than that of the group with added tapioca flour. Whereas the reverse was the case for the yellowness. With increasing tapioca flour content, the springiness, gumminess, cohesiveness, and chewiness of Jeung-Pyun were increased, and the hardness increased. In sensory evaluation cell uniformity and chewiness were the highest in the 20% added group. The hardness of the sense examination increasing with increasing tapioca floor content. The overall quality of Jeung-Pyun was the lowest in the 30% added group.

Effect of Aqueous Extracts from Rubus coreanus Miquel and Angelica gigas Nakai on Anti-tumor and Anti-stress activities in mice (복분자와 당귀 열수추출물의 마우스를 이용한 항암 및 항스트레스 효과)

  • Kim, Jung-Hwa;Kim, Cheol-Hee;Kim, Hyou-Sung;Kwon, Min-Chul;Song, Young-Kyu;Seong, Nak-Sul;Lee, Seung-Eun;Yi, Jae-Seon;Kwon, Oh-Woung;Lee, Hyeon-Yong
    • Korean Journal of Medicinal Crop Science
    • /
    • v.14 no.4
    • /
    • pp.206-211
    • /
    • 2006
  • This study was performed to examine antitumor activities of Rubus coreanus Miquel and Angelica gigas Nakai extracts against sarcoma-180 and anti-stress activities in ICR mice. The variation of body weights of the 20 days of Rubus coreanus extracts-administrated mice group was very low. The survival rate (T/C %) of Rubus coreanus extract administrated group was 161% after 50 days from the inoculation of sarcoma-180 and the increment of their body weights was suppressed. Anti-stress effect of the extracts of R. coreanus and A. gigas were estimated by maeasuring blood chemical value and internal organs weight in ICR mice. The extracts of R. coreanus reduced the cholesterol and glucose to the normal level in the all stress animal models. The extracts of R. coreanus reduced the hypertrophy of the internal organs such as adrenal, spleen and liver to the regular level.

Effect of Application Method and Concentration of Plant Growth Retardants On Plant Quality of Potted Saxifraga rosacea Moench

  • Park, Yeon Hee;Kim, Yoon Jin;Jung, Hyun Hwan;Kim, Ki Sun
    • FLOWER RESEARCH JOURNAL
    • /
    • v.19 no.3
    • /
    • pp.127-138
    • /
    • 2011
  • Four different plant growth retardants (PGRs), paclobutrazol, flurprimidol, daminozide, and chlormequat, were applied to potted Saxifraga rosacea 'Kumoma' and 'Kumoma-Gusa' plants for control of the growth and flowering. Paclobutrazol (10, 20, 40, $80mg{\cdot}L^{-1}$), flurprimidol (5, 10, 20, $40mg{\cdot}L^{-1}$), daminozide (500, 1000, 2000, $4000mg{\cdot}L^{-1}$), and chlormequat (50, 100, 200, $400mg{\cdot}L^{-1}$) were applied to the plants by a foliar spray or drenching. In 'Kumoma', application of $40mg{\cdot}L^{-1}$ paclobutrazol by a foliar spray or drenching reduced plant height by 12.5 and 12.6 cm, and flower length by 3.4 and 3.3 cm, respectively. On the other hand, in 'Kumoma-Gusa', drenching of paclobutrazol reduced plant height by 10.7 to 12.6 cm and flower length by 2.0 to 3.9 cm with increasing concentration, but the number of florets almost fell to 20 as compared to 40.5 in the control. 'Kumoma-Gusa' plants drenched with $80mg{\cdot}L^{-1}$ paclobutrazol and sprayed with $40mg{\cdot}L^{-1}$ flurprimidol had the shortest heights of 10.7 and 9.9 cm, and floral length of 2.0 and 1.5 cm, respectively. A flurprimidol drenching at $40mg{\cdot}L^{-1}$ delayed the harvest by 3-13 days as compared to the control and the smallest number of florets, 15.6, was observed in this treatment. In both cultivars, chlormequat and daminozide did not effectively influence the growth and flowering. However, number of florets increased to more than 41 at all concentrations and up to 63, the greatest floret number, with chlormequat drench in 'Kumoma-Gusa'. These results demonstrated that over $40mg{\cdot}L^{-1}$ of paclobutrazol or 5 to $20mg{\cdot}L^{-1}$ of flurprimidol could be used as PGRs to control the growth of floral length and flowering for improving potted plant quality in S. rosacea 'Kumoma' and 'Kumoma-Gusa'.

SPONTANEOUS ERUPTION GUIDANCE OF UNERUPTED TOOTH AFTER SURGICAL REMOVAL OF COMPLEX ODONTOMA (복잡 치아종의 외과적 적출후 미맹출치의 자발적 맹출 유도)

  • Park, Sung-Youn;Nam, Dong-Woo;Kim, Hyun-Jung;Kim, Young-Jin;Nam, Soon-Hyeun
    • Journal of the korean academy of Pediatric Dentistry
    • /
    • v.30 no.3
    • /
    • pp.489-494
    • /
    • 2003
  • Odontomas are the common type of odontogenic tumors and generally they are asymptomatic, depending upon size, location and their limited growth potential. they are rarely diagnosed before the second decade of life, and the frequently lead to impaction or delayed eruption of permanent teeth. Odontomas are classified of compound as compound or complex by morphology. Complex odontomas are unorganized masses of odontogenic tissues, morphologically not resembling the teeth, account for approximately 25 percent of all odontomas, 22 percent of odontogenic tumor of the jaws, and have a predilection for the posterior mandible in males. The etiology of odontomas is unknown, although local trauma, infection, and genetic factors have been suggested. Usually, treatment of odontoma is conservative sugical removal and their is little probability of recurrence. This paper describes two cases of complex odontomas diagnosed in children due to impaction of maxillary first molar in all cases, the surgical excision of the lesions was performed. Follow-up after 2 years, showed spontaneous eruption of the first permanent molar to the occlusal plane.

  • PDF

Investigation of Forest Maschines and Tools in Central Europe (1) - On the Ax - (유럽 중부지방(中部地方)의 산림작업용(山林作業用) 기기(機器)의 조사검토(調査検討) (1) - 도끼편 -)

  • Ma, Sang Kyu
    • Journal of Korean Society of Forest Science
    • /
    • v.53 no.1
    • /
    • pp.62-74
    • /
    • 1981
  • The developed record of forest maschines and tools in West Germany, Austria and Swiss, their technical characteristics and the working methods with them have been tried to investigate through the study of literature and observation. The aim of this investigation is to find out and introduce the technical information for training our forest men with them and for improving or developing our forest maschines and tools. Although ax chosen as first report for this aim is the oldest tool in the mankind history, still this is widely using in the forest work. And this has some special working filed that any other maschines could not overcome and sometimes should be recommended in the agronomical sideview. Through this investigation several points could be proposed as the technical informations when we will try to improve our ax 1. Radius of as-face curvature is proposed to be 150 mm and it's central point to be passed at one third point near to ax-eye. 2. Cutting angle is proposed to be $30^{\circ}$, ax-thick at 12 mm distance from ax-face to be 4 mm, thick at 30 mm distance from face to be 5 to 6 mm and ax-face width to be $125{\pm}5mm$. 3. Neck size is proposed to be $3.5{\pm}0.5{\times}5.5{\pm}0.5cm$ with a little curvature and neck thick from ax-house to be more than 1.5 cm. 4. Ax weight is proposed to be 1,000 gr with the stupid back and the sharp front. 5. The handle length of ax will be followed to the arm length of our forest workers.

  • PDF

Permeability and Strength of Cements Exposed to Supercritical CO2 for Varying Periods (초임계 CO2 - 시멘트 반응 전후의 투수율 및 강도 변화)

  • Lee, Hikweon;Kim, Kideok;Kim, Taehee;Kim, Gyo-Won
    • The Journal of Engineering Geology
    • /
    • v.26 no.1
    • /
    • pp.117-128
    • /
    • 2016
  • Chemical reaction tests were performed to assess the properties of hardened specimens of cement pastes (KS-1 Portland and Class G) exposed to supercritical CO2 for 1, 10, and 100 days. After exposure, the samples' measured permeability and strength were compared with values measured for pristine samples. The pristine cements had permeabilities of 0.009~0.025 mD, which increased by one order of magnitude after 100 days of exposure (to 0.11~0.29 mD). The enhancement of permeability is attributed to the stress release experienced by the samples after removal from the pressure vessel after exposure. Despite its enhancement, the measured permeability mostly remained lower than the API (American Petroleum Institute) recommended maximum value of 0.2 mD. The degradation of the cement samples due to exposure to supercritical CO2 led to a layer of altered material advancing inwards from the sample edges. The Vickers hardness in the altered zone was much higher than that in the unaltered zone, possibly owing to the increase in density and the decrease in porosity due to the carbonation that occurred in the altered zone. Hardness close to the edge within the altered zone was found to have decreased significantly, which is attributed to the conversion of C-S-H into less-strong amorphous silica.

An Exploration on the Creative Disposition, Creative Thinking Power, Multiple Intelligences and Morality of Gifted Children (유소년영재의 창의적 성향.창의적사고력.다중지능.도덕성에 관한 탐색)

  • Ryu, Bong-Sun;Lee, Gyoung-Eun;Hong, Seong-Yong
    • Journal of Gifted/Talented Education
    • /
    • v.21 no.4
    • /
    • pp.979-992
    • /
    • 2011
  • Gifted children cultivate their many talents through experience. For the purpose of revealing the talents or abilities of gifted children, it is necessary to provide them with various types of environment for their exploration from the early stage of their school age. In addition, knowing their concern, aptitude and interest from the early stage of their school age will be much helpful for them to grow, advance and search for their future career path. Accordingly, the purpose of this study is to examine the definitional and cognitive characteristics of gifted children through tests on the creative disposition, creative thinking power, multiple intelligences and morality of gifted children at the early stage of their school age in order to provide basic information on the gifted children studies. Accordingly, 90 gifted children were selected as the participants of this study through observation and recommendation. The result showed much difference between the second grade and the third grade in their creative disposition, creative thinking power, multiple intelligences and morality according to school year. As for the difference according to gender, the second grade female students showed meaningful differences in the sub-domain of creative disposition, multiple intelligences and morality and the third grade showed no differences. Such study result shows that students in upper school year clearly have their own sense of purpose.

Professional Development and Perceptual Changes in Gifted Education by Regular Classroom Teachers (일반교사들의 영재교육에 대한 인식변화와 전문성 신장)

  • Chun, Miran;Huh, Mooyul
    • Journal of Gifted/Talented Education
    • /
    • v.24 no.5
    • /
    • pp.781-806
    • /
    • 2014
  • The purpose of this study is to examine the change in the beliefs of regular classroom teachers after participating in a gifted education lectures and practicum as well as the effectiveness of the lectures and practicum. Each teacher was asked to complete a pre-/ a mid-/ and post-journal, detailing their expected characteristics and then describing what occurred and how their initial expectations were altered. The teachers mentioned high thinking skills, creativity, fast problem solving skills, and a lack of communication skills as intellectual characteristics of gifted students and high motivation and task commitment as social characteristics. They mentioned the characteristics in textbooks on pre- and mid-journals, but presented their observations in post-journals such as lack of communication skills, competitive spirit, and frustrations. The study found that teachers broadened their view of giftedness, recognized the need to adapt instructions for gifted students, realized the necessity of knowing the students to differentiate instruction patterns, and emphasized teaching-learning strategies for the gifted. These results contribute to the promise of having regular classroom teachers engage in a field experience with gifted students to supplement discussions about gifted education lectures.

Residue Determination of Chlorothalonil in Sesame and Soil (Chlorothalonil의 참깨 및 토양중 잔류소장에 관한 연구)

  • Lee, Kang-Bong;Cho, Ill-Kyu;Shim, Jae-Han;Suh, Yong-Tack
    • Korean Journal of Environmental Agriculture
    • /
    • v.9 no.1
    • /
    • pp.15-22
    • /
    • 1990
  • The efects of application time on the persistence of chlorothalonil in sesame plants and its persistence in soil were studied in the field. A procedure was used which permited the analysis of residues of Chlorothalonil (DACONIL 2787) in sesame(Sesamum indicum L.)and soil. The procedure was based on the multiresidue analytical method using an polarized acetonitrile solution or acidified acetone as the extracting solvent. The DACONIL 2787 is separated from the fat in the extracts by using an activated alumina and Florisil chromatogaphic column. Residues of DACONIL 2787 were determined by subjecting the alternate eluate from the Florisil column to gas chromatographic analysis(ECD). Residue of chlorothalonil in sesame are proved to 0.06 ppm for six sprays, 3rd day before harvest The half-life of chlorothalonil in soil proved to be 8.9 days and residues of chlorothalonil was only 0.03 ppm 100 days after application of 15 ppm.

  • PDF