• Journal of Dental Rehabilitation and Applied Science
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• v.32 no.4
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• pp.301-306
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• 2016

It is very hard for edentulous patients to satisfy retention and stability with their complete denture. Especially, for patients with systemic diseases such as Parkinson's disease causing involuntary and limited movements, fabricating complete dentures may be challenging to both dentists and patients due to functional limitations. To overcome this problem, overdentures can be used through conserving retained roots. In this case, a 45-year-old male patient had to extract numerous teeth due to dental caries, and at the time of visit he was taking drugs for diabetes and Parkinson's disease for a period of long time. A complete denture was applied to maxilla, and for mandible, an overdenture on two preserved retained roots was applied where its retention and stability were obtained by magnetic attachments. This case reports that overdenture with retained roots improved overall functional limitations.

• Korean Journal of Food Science and Technology
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• v.35 no.4
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• pp.690-695
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• 2003

Physiological activities of 40% ethanol extracts of Phellinus ribis were studied by employing several biological and biochemical assays. The extracts of Phellinus ribis displayed nitrate-scavenging activities (NSA) at pH 1.2 as with 64% NSA with 1.0 mg/mL of the extracts. They also had 91% 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activities at the concentration of 1.0 mg/mL. Antioxidant activities of the extracts (at 0.5 mg/mL) on the autoxidation of linoleic acid (p<0.001) were also observed.. The inhibitory effect of the extracts on angiotensin converting enzyme was 11%. Cytotoxic effects of Phellinus ribis extracts against human cancer cell tines were also examined using MTT assay. The extracts (at 50 mg/mL) had severe growth inhibitory effects on A549, Hela, AGS, and SK-Hep-1, which were 8, 44, 76 and 42%, respectively. Ames test indicated that the extracts had no mutating effects on Salmonella typhimurium TA98 and TA100.

• The Journal of the Korean bone and joint tumor society
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• v.15 no.1
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• pp.69-74
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• 2009

Soft tissue sarcomas of popliteal fossa are rare, accounting for less than 5% of all soft tissue sarcomas of the extremities. In an extracompartmental space such as the popliteal, cubital fossa and inguinal space, where major vessels and nerves traverse, performing resections with wide margin is difficult and sometimes marginal margin is inevitable for limb salvage. For popliteal tumor resection, posterior approach would be a classic method. For tumors with small size and not adherent to surrounding structures, tumor is easily resected by this approach and dissection of nerve sheath or adventitia of vessel. On the contrary, tumors of large size and infiltrating the posterior structure of knee joint may show difficulty in en-bloc resection itself. These cases were candidates for amputation. Furthermore, tumors involving both popliteal fossa and anterior compartment usually had no choice but to have an amputation to prevent local recurrence. We regarded soft tissue sarcoma showing this kind of presentation as bone tumor having extraosseous mass. We performed wide en-bloc resection of proximal tibia and fibula along with sarcoma involving both compartment on liposarcoma of 47-year old man.

• Clinics in Shoulder and Elbow
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• v.12 no.2
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• pp.126-136
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• 2009

Purpose: We evaluated the correlation of the anatomic parameters of the acromion those represent on the magnetic resonance image (MRI) of impingement syndrome. Materials and Methods: From June, 2004 to December, 2005, 71 cases were surgically proven to be impingement syndrome, and the anterior acromial hooking angle, the lateral acromial hooking angle (AAHA and LAHA) and the acromial hooking index (AHI: the sum of the AAHA and LAHA) were compared to 16 control cases. At the same period, 55 cases were surgically proven to be partial or full thickness rotator cuff tear, and age, gender and twelve anatomic parameters, including the acromial type, the acromial angle, the anterior covering, the acromial slope, the AAHA, the lateral acromial angle, the acromial torsional angle, the lateral acromial angulation, the LAHA, the lateral covering, the acromiohumeral distance and the AHI were assessed. Results: The AAHA and AHI were increased as impingement syndrome proceeded. The acromial type and acromial angle, and the AAHA, LAHA and AHI showed significant differences between the controls and the rotator cuff tear patients on univariant analysis. On multivariant analysis, gender was most strongly correlated with rotator cuff tear. Age, AAHA and the acromial angle showed similar correlation, respectively. Conclusion: The coronal acromial shape is correlated with rotator cuff tear, and it is important to correct the lateral acromial shape when performing acromioplasty.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.1
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• pp.284-290
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• 2020

This study was undertaken to determine the effects of SNAGs (sustained natural apophyseal glides) and visual convergence biofeedback on the proprioception and neck disability of patients with chronic neck dysfunction. A total of 31 patients with neck dysfunction were assigned to either SNAGs (n = 16) or biofeedback (n = 15). The groups were assessed for proprioception and neck disability, before and after the intervention. The SNAGs were performed using belt with flexion, extension and right-left rotation, whereas biofeedback training included visual feedback training with deep neck flexor. Intervention was implemented for 20 minutes, twice a week for 4 weeks. Biofeedback training a showed significant effect on the joint position sense (left and right rotation) as compared to the SNAGs group (p< 0.05), whereas neck disability index was significantly effective for SNAGs (p< 0.05). Ed. Notes: The previous statement lacked clarity. I have suggested the edit as per my understanding. Please review and revise appropriately, if required. Therefore, the SNAGs technique is effective for neck function, and biofeedback training is a positive intervention method for enhancing the proprioceptive sensation. In future studies on patients with neck pain, it may be possible to select an intervention method based on the characteristics of the disease.

• Proceedings of the KSCN Conference
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• 2003.11a
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• pp.1073-1074
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• 2003

본 연구는 고학력 중년 여성을 대상으로 취업 여부에 따른 영양섭취 상태의 차이를 분석하여 고학력 중년 여성의 영양 및 건강관리를 위한 대책 마련의 기초자료로 활용하고자 시행되었다. 연구 대상자의 선정은 유의추출 방법으로 전업 여성은 고학력자 비율이 높은 대전시의 일정 지역에 거주하는 기혼여성으로 하였고, 취업여성은 여러 직업의 특성으로 인한 교란(confounding)을 줄이기 위하여 고학력 여성의 비율이 높은 기혼의 교사로 한정하였다. 연령에 의한 교란을 방지하기 위하여 연령대별로 동일 비율로 무작위 추출하여 전업여성 250명, 취업여성 236명을 대상으로, 24시간 회상법을 이용하여 조사 전일 하루동안의 식이 섭취 내용을 개별 면담으로 조사하였다. 1일 영양소 섭취 조사 결과 취업여성은 전업여성에 비해 인, 비타민 B$_1$, B$_2$를, 전업여성은 취업여성에 비해 지방 및 동물성 지방, 나트륨, 비타민 C, 엽산을 많이 섭취하고 있었다. P/M/S비는 전업여성 1/1.19/1.05, 취업여성 l/l.05/0.87로 나타나 취업여성이 전업여성에 비해서, 그리고 한국인 영양권장량의 기준(1/1/1)에 비해서 포화지방의 비가 낮았다. 또한 지방 에너지 구성비도 전업여성(24.38%)이 취업여성(23.29%)에 비해 높았고, 총 열량에 대한 동물성 지방의 섭취비율이 전업여성 12.44%, 취업여성 11.46%으로 나타나 전업여성이 취업여성에 비해 동물성 지방, 포화지방비, 지방에너지 구성비가 모두 높았다. 영양권장량에 대한 영양소 섭취 백분율에서 전업여성과 취업여성 모두 칼슘과 아연을 권장량에 비해 낮게 섭취하고 있었고, 질적 영양지수(INQ)도 두 군 모두에서 칼슘이 가장 낮게 나타났다. 인의 영양밀도(Nutrient Density)가 취업주부에서 높았던 점 외에는 영양밀도와 영양소 적정섭취비(NAR) 모두에서 비타민 B$_1$, B$_2$가 전업여성에 비해 취업여성이, 비타민 C가 취업여성에 비해 전업여성이 더 높았다. 한편 두 군 모두 INQ가 가장 높은 영양소는 인이었고, INQ가 가장 낮은 영양소는 칼슘으로 나타났으며, INQ가 1 미만인 영양소는 칼슘과 함께 철분으로 나타났다. 이는 1998년도 국민건강영양조사 결과에서 45세 이상 여성의 경우 관절염, 요통.좌골통, 디스크 등 근골격계질환 유병률이 남자보다 3배정도 높게 나타난 결과에 비추어볼 때 이들 관련 영양소에 대한 섭취 방안 지도의 필요성을 제시하고 있다. 결론적으로 고학력 중년 여성중 전업여성에 대해서는 지방 특히 동물성 지방 식품 섭취에 대한 적절한 영양교육과 식사관리 지도가 요구된다 하겠다. 또한 고학력 중년 여성은 취업 여부에 관계없이 칼슘과 철분이 많이 함유된 식품으로 식사량을 증가시켜 주는 영양 지도 및 영양 보강 대책이 요구되며, 칼슘과 인의 적정섭취비가 되도록 인의 섭취를 낮추는 식생활 지도가 필요하다.

• Journal of Life Science
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• v.28 no.12
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• pp.1455-1460
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• 2018

Due to a rapidly expanding aging population, the incidence of degenerative bone disease has increased, and efforts to handle the issue using regenerative medicine have become more important. In order to control various bone diseases such as osteoarthritis and osteoporosis, regenerative medicine utilizing adult stem cells has been extensively studied. And it is now clear that the mitochondrial energy metabolism, oxidative phosphorylation, is important for the process of stem cell differentiation. Interestingly, a recent study reported that salicylate promotes mitochondrial biogenesis by regulating the expression of $PGC-1{\alpha}$ in murine cells. However, the possible effects of salicylate on osteogenic differentiation through increased mitochondrial biogenesis in stem cells remain unknown. Thus, here we investigated whether salicylate could influence osteogenic differentiation and mitochondrial biogenesis of periosteum-derived mesenchymal stem cells (POMSCs). We found that salicylate treatments of POMSCs undergoing osteogenic differentiation increased the activity of alkaline phosphatase, a well-known early marker of bone cell differentiation. In addition, we observed that mitochondrial mass was increased by salicylate treatments in POMSCs. Together, these results indicate that salicylate can enhance osteogenic differentiation and mitochondrial biogenesis in POMSCs. Therefore, the findings in this study suggest that small molecules augmenting mitochondrial function such as salicylate can be a novel modulator for osteogenic differentiation and regenerative medicine.

• Journal of Dental Rehabilitation and Applied Science
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• v.37 no.2
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• pp.88-94
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• 2021

Purpose: The purpose of this study was to evaluate the anti-inflammatory effects of non-thermal atmospheric pressure plasma (NTP) on human gingival fibroblasts (HGFs) for clinical application of periodontal treatment. Materials and Methods: HGFs were treated with Porphyromonas gingivalis (Pg) lipopolysaccharide (LPS). Customized NTP device was developed for periodontal in vitro study. Cell viability was evaluated with cell counting kit-8. The levels of inflammatory cytokines, including interleukin (IL)-8 and 6, were determined by enzyme-linked immunosorbent assay. Results: When NTP was applied, the cell viability did not change significantly, and there was no difference for 6 h and 24h. When Pg LPS was treated to HGFs, the secretion of IL-8 and IL-6 was increased compared to the control group. But when the NTP was applied, the secretion of them was significantly decreased. Conclusion: NTP did not affect cell viability of HGFs. And it inhibited the LPS-induced production of IL-8 and IL-6.

• Journal of Dental Rehabilitation and Applied Science
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• v.37 no.1
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• pp.48-60
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• 2021

Patients who have extruded anterior teeth and deep bite with pathologic tooth migration, it is necessary not only periodontal treatment for reduce inflammation, but also orthodontic treatment for intrusion of anterior teeth. However, it is difficult to place the orthodontic brackets due to the deep bite, and there is a problem that the extrusion of the posterior teeth occurs more easily than the intrusion of the anterior teeth biomechanically. In particular, in patients with long face, relative intrusion of the anterior teeth by extrusion of the posterior teeth causes the clockwise rotation of the mandible and makes the facial profile worse. Therefore the biomechanical consideration and appliance design that can block these problems are required from the treatment plan. This is a patient who had a deep overbite with extruded anterior teeth, treated by periodontal treatment and intrusion of mandibular anterior teeth using cute brackes and miniscrews, and resulted in favorable maintenance during 8-year retention.

• Journal of Korean Medicine Rehabilitation
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• v.31 no.1
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• pp.119-135
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• 2021

Objectives This review aims to analyze the current research trend in the usage of bee venom (BV) acupuncture for articular diseases of single type joint. Methods We collected 74 articles on BV acupuncture clinical study for articular diseases of single joint by searching Korean web databases 'Journal of Korean Medicine Rehabilitation', 'Oriental Medicine Advanced Searching Integrated System', 'Korean Traditional Knowledge Portal' from 1999 to 2020 August. Results We summarized the most frequent clinical treatment methods of BV acupuncture for articular diseases of single type joint. Research focused on specific diseases in application of BV acupuncture about some articular type diseases of single joint. It is assumed that the details of treatment for each joint are not related to the type of joint. In clinical study of BV acupuncture, reproducibility was mostly insufficient. Conclusions BV acupuncture clinical study for articular diseases of single joint should be proceed for a number of subjects, to treat various types of disease, by using more safe and detailed treatments.