• 제목/요약/키워드: 관계절

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Expression and Clinical Significance of the N-myc Downstream Regulated Gene-1 in Hypopharyngeal Cancer (하인두암에서의 N-myc Downstream Regulated Gene-1 발현의 임상적 의의)

  • Sohn, In-Kyung;Han, Nam-Soo;Shin, Yoo-Seob;Kim, Jang-Hee;Kim, Chul-Ho
    • Korean Journal of Head & Neck Oncology
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    • v.27 no.1
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    • pp.22-26
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    • 2011
  • 목 적 : 두경부 암은 발생 순위에서 전체 6위에 해당하는 다빈도 암이나 최근 20여년 동안의 노력에도 불구하고 두경부 암의 독톡한 특성상 생존률에서 뚜렷한 향상을 보이지 못하고 있다. 특히, 하인두 암은 원발 부위의 점막하 침윤이 흔하며, 주변 림프절 전이와 원격 전이가 흔하고, 2차 원발 암종 발생이 흔하여 두경부 암 중에서도 가장 불량한 예후를 보이고 있는 악성 종양이다. 최근에 이러한 암을 치료하고 진단하기 위한 방법으로 분자생물학적 접근법들이 많이 시도 되고 있으며, 그 중 하나로 N-myc downstream regulated gene-1(Ndrg-1)이라는 유전자가 유방, 전립선, 방광 암 등의 타 악성 종양에서 종양의 전이 및 진행 양상과 관련되어 있다는 보고가 있었다. 이에 본 연구는 하인두 암에서의 Ndrg-1의 발현 양상을 살펴보고 이와 임상 양상과의 연관관계를 살펴보고자 하였다. 방 법 : 1996년부터 2003년까지 수술 받은 하인두 암 환자 56명을 대상으로 면역조직화학검사를 시행하여 Ndrg-1 발현을 확인하였고, 3명의 신선 조직을 대상으로 RT-PCR, Western blot을 시행하였다. 결 과 : Ndrg-1은 RT-PCR에서 정상 조직과 악성종양 조직 모두에서 비슷한 수준으로 발현되었다. 그러나 Western blot에서는 정상 조직에서 뚜렷한 증가 양상을 보여 타 연구와 동일한 결과를 보였고, 이는 불필요하며 비효율적인 mRNA수준에서의 발현이 있지만 최종적인 단백 산물 발현에서는 암종의 진행과 연계되어 악성 종양 진행군에서 발현이 억제되는 결과로 해석된다. 면역조직화학검사에서는 정상 상피조직에서 Ndrg-1 발현이 확인되었으며, 통계적으로 유의하지는 않으나 불량한 예후를 가진 그룹에서 대체로 발현이 억제되는 악성 종양과의 역 연관 관계를 확인할 수 있었고, 특히 림프절 전이를 보인 그룹과 그렇지 않은 그룹 사이에서는 통계적으로 유의미한 결과가 확인되었다. 결 론 : 즉, 림프절 전이가 없는 그룹에서 Ndrg-1이 종양의 전이에 관여할 것이라는 타 연구와 일관된 결과로 하인두 암에서도 그 역할이 있음을 나타내는 결과라 할 수 있다.

Pollen Morphology of Euphorbia Subsection Meleuphorbia (대극속 Meleuphorbia아절의 화분형태학적 연구)

  • Noh, Mi-Ae;Park, Ki-Ryong
    • Applied Microscopy
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    • v.38 no.4
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    • pp.329-338
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    • 2008
  • Pollen morphological studies using light and scanning electron microscopy were conducted to determined the sub-sectional boundary and species relationship of 12 species of subsect. Meleuphorbia and related taxa. Based on the sculpturing patterns of pollen grains and UPGMA tree from numerical analyses using 8 quantitative pollen characters 12 species were divided into two types: type I, having microperforate pollen grains in E. epicyparissias, E. inermis, E. pillansii, E. obesa, E. bubalina, E. meloformis, E. nesemanii, and E. jansenvillensis, and type II, having fossulate sculpturing pattern in E. longituberculosa, E. monteiri, E. caput-medusae and E. grantii. The resulting pollen data suggest that the subsect. Meleuphorbia should not be a natural group, but closely related to the species from subsect. Anthacantha and sect. Treisia and sect. Medusea. Thus, the pollen morphological data recommended to combine above taxa as a single taxonomic group.

The Relationship between English Proficiency and Syntactic Complexity for Korean College Students (한국 대학생의 에세이에 나타난 영어 능력 수준과 통사적 복잡성 간의 관계 탐색)

  • Lee, Young-Ju
    • The Journal of the Convergence on Culture Technology
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    • v.7 no.3
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    • pp.439-444
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    • 2021
  • This study investigates the relationship between syntactic complexity and English proficiency for Korean college students, using the recently developed TAASSC(the Tool for the Automatic Analysis of Syntactic Sophistication and Complexity) program. Essays on the ICNALE(International Corpus Network of Asian Learners of English) corpus were employed and phrasal complexity indices and clausal complexity indices, respectively were used to predict English proficiency level for Korean students. Results of stepwise regression analysis showed that indices of phrasal complexity explained 8% of variance in English proficiency, while indices of clausal complexity accounted for approximately 11%. That is, indices of clausal complexity were slightly better predictors of English proficiency than indices of phrasal complexity, which contradicts Biber et at.(2011)'s claim that phrasal complexity is the hallmark of writing development.

Investigation into Longitudinal Writing Development Using Linear Mixed Effects Model (선형 혼합 모형을 통해 살펴본 쓰기 능력의 장기적인 발전 양상 탐색)

  • Lee, Young-Ju
    • The Journal of the Convergence on Culture Technology
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    • v.8 no.2
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    • pp.315-319
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    • 2022
  • This study investigates longitudinal writing development in terms of syntactic complexity using linear mixed effects (LME) model. This study employs essays written by four case study participants. Participants voluntarily wrote essays outside of the classroom and submitted the first and second drafts, after reflecting on the automated writing evaluation feedback (i.e., Criterion) every month over one year. A total of 48 first drafts were analyzed and syntactic complexity features were selected from Syntactic Complexity Analyzer. Results of LME showed that there was a significant positive linear relationship between time and mean length of T-unit and also between time and the ratio of dependent clauses to independent clauses, indicating that case study participants wrote longer T-units and also a higher proportion of dependent clauses over one year.

The Effect of SBAR Reports on Communication Clarity and Nurse-Physician Collaborative Relationships: A One Group Pretest-Posttest Design (간호사의 SBAR 환자보고가 의사소통의 명확성과 간호사와 의사의 협력관계에 미치는 영향: 단일군 전후실험 설계)

  • Kim, Hwa Young;Jeong, Yeon Jin;Kang, Jiyeon;Mun, Hyun Suk
    • Journal of muscle and joint health
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    • v.23 no.2
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    • pp.105-113
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    • 2016
  • Purpose: The purpose of this study was to investigate the effect of Situation-Background-Assessment-Recommendation (SBAR) reports on communication clarity and nurse-physician collaborative relationships. Methods: SBAR forms in one group were measured at baseline, at 2 weeks, and at 4 weeks postintervention. The subjects were 30 nurses who worked in a general ward of a general hospital in B city, Korea. A 45-minute SBAR education was provided to all subjects. Data was collected between September to October 2015. The collected data was analyzed using a repeated measure ANOVA. Results: After SBAR reports, levels of nurse's communication clarity and nurse-physician collaborative relationships were significantly higher than levels before SBAR reports. Conclusion: SBAR reports improved the communication clarity and nurse-physician collaborative relationships. It is recommended to use a lot of SBAR in clinical practice.

Design and Implementation of an Instance Access Handling System for Supporting Schema Evolution (스키마 진화를 지원하는 인스턴스 접근처리시스템의 설계 및 구현)

  • Jin, Min;Kim, Bong-Jin
    • The Transactions of the Korea Information Processing Society
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    • v.7 no.12
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    • pp.3753-3761
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    • 2000
  • There exist several versions of schema and instances created under different versions of the schema concurrently in the database in schema evolution environments. This paper proposes a mechanism for accessing instances regardless of versions in schema evolution environments in object relational databases. Access handling routines are used in accessing to the instances through the undefined attributes in the versions in which they were created. The change of semantic information of attributes is supported. Access handling routines are defined for each pair of semantics rather than defining backdate/update functions for each pair of versions of a class. A query language that accommodates version and semantic information is defined through the extension of the primitive SQL format.

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Influence of Interpersonal relation and Job Stress on Nursing Performance of Male Nurses (남자간호사의 대인관계능력과 직무 스트레스가 간호업무성과에 미치는 영향)

  • Cho, Mi-Kyoung;Kim, Chul-Gyu;Mo, Hyeong-Jung
    • Journal of muscle and joint health
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    • v.22 no.3
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    • pp.195-204
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    • 2015
  • Purpose: The purpose of this study was to identify the effect of interpersonal relation and job stress on nursing performance among male nurses. Methods: This study was cross-sectional descriptive one. The data were collected from self-administered questionnaires by 110 male nurses members affiliated with the Korean Man Nurses Association. The data were analyzed using descriptive statistics, independent t-test, one way ANOVA with Duncan test, Pearson correlation, and stepwise multiple regression with the SPSS/WIN 21.0. Results: The average scores of interpersonal relation, job stress, and nursing performance were respectively 3.64, 3.10, 3.63. Nursing performance was high in married, good health condition, manager, and high salary among male nurses. Nursing performance showed significant positive correlation with interpersonal relation (p<.001), and a significant negative correlation with job stress (p=.010). Influencing factors of nursing performance among male nurses were interpersonal relation, health status, total duration of career, position, and the adjusted $R^2$ of the regression model was 42%. Conclusion: The results suggest that we need to develop a training program to improve the nursing performance of the male nurses.

The Effect of Social Networks and Information Literacy Competency on Job Competency of Community Health Practitioners (보건진료소장의 사회적 관계망, 정보활용역량이 직무역량에 미치는 영향)

  • Ryu, Si-Ok;Son, Yedong;Ahn, Okhee
    • Journal of muscle and joint health
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    • v.28 no.2
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    • pp.140-151
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    • 2021
  • Purpose: This descriptive research study aimed to investigate the effect of social networks and information literacy competency on the job competency of community health practitioners. Methods: The participants of this study were 170 community health practitioners working in the southern and northern regions of J, Korea. Data collection was carried out from March 6, 2018, to April 17, 2018, using a structured self-report questionnaire. Data were analyzed using the SPSS / WIN 23.0 statistical program. Results: Information literacy competency showed 45.5% explanatory power for job competency. However, there was no significant relationship between social networks and job competency. Conclusion: It is helpful to establish a systematic education system for job training and to expand educational opportunities using varied methods like online or mobile-based teaching to increase the job competency of community health practitioners.

The Effects of Self-esteem and Major Satisfaction on Interpersonal Relationship Ability of Nursing Students Who Have Experienced Clinical Practice (임상실습을 경험한 간호대학생의 자아존중감, 전공만족도가 대인관계능력에 미치는 영향)

  • Lee, Kyoung Eun
    • Journal of muscle and joint health
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    • v.27 no.3
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    • pp.316-324
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    • 2020
  • Purpose: This study aimed to investigate the relationship between the subject's self-esteem, major satisfaction, and interpersonal ability, and to identify factors that affect interpersonal relationships. Methods: The subjects of this study were 135 nursing college students in the third and forth grades enrolled in a college located in B Metropolitan City. Data were collected using a structured questionnaire was used, and the data collection period was from July 13, 2020 to August 9, 2020. Results: The average degree of self-esteem, major satisfaction, and degree of interpersonal relationship were relatively high. The interpersonal relationship ability according to the general characteristics of the subjects showed significant differences in religion, residence type, departmental friend, health status, and satisfaction with clinical practice. The factors influencing the subject's interpersonal relationship ability were in the order of self-esteem, major satisfaction, good health, and traces of residence. Conclusion: Based on the results of this study, it is considered necessary to develop a nursing intervention program that can enhance the interpersonal skills of nursing college students.

Relationships of Activities of Daily Living and Body Image with Quality of Life in Stroke Patients: Mediating Effects of Interpersonal Relations (뇌졸중 환자의 일상생활 수행능력, 신체상이 삶의 질에 미치는 영향: 대인관계 매개효과 중심)

  • Kim, Minju;Park, Hyomin
    • Journal of muscle and joint health
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    • v.28 no.2
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    • pp.183-191
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    • 2021
  • Purpose: This study was conducted to identify factors associated with stroke patients' quality of life (QOL) and examine the mediating effects of interpersonal relations in the relationships of activities of daily living (ADL) and body image with QOL. Methods: In this study, 160 stroke patients were recruited from an outpatient clinic of a university hospital and rehabilitation clinic of a long-term care hospital. Participants completed a questionnaire which included sociodemographic characteristics, ADL, body image, interpersonal relation, and QOL. Descriptive statistics, t-tests, ANOVA, Pearson's correlation coefficients, multiple regression analysis, and process macro mediation analysis were conducted using SPSS. Results: The mean scores were 91.01 (range 6~100) for ADL, 61.19 (range 40~79) for body image, 87.53 (range 29~123) for interpersonal relations, and 186.67 (range 71~243) for QOL. Multiple regression analyses showed that ADL, body image, interpersonal relations, and participation in group activities after stroke were significantly associated with QOL among stroke patients (p<.05). There were no mediating effects of interpersonal relations in the relationships of ADL and body image with QOL (p>.05). Conclusion: This study showed that there is a need for physical, psychological, and social recovery to improve the QOL of stroke patients.