• Journal of the Society of Cosmetic Scientists of Korea
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• v.43 no.1
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• pp.43-52
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• 2017

EtOAc fractions of Magnolia obovata (M. obovata) Bark extracts were studied for the potential ingredient as a safe and effective whitening cosmetic material. The concentration of active substances honokiol was determined by HPLC. In vitro, the fractions reduced the extracellular and intracellular melanin contents in B16F10 cells in dose dependently and inhibited extracellular melanin secretion ($IC_{50}=11.05{\mu}g/mL$). The $12.5{\mu}g/mL$ treatment of maximum concentration effectively inhibited up to about 60% to the amount of extracullular melanin. Also, the $12.5{\mu}g/mL$ treatment of maximum concentration effectively inhibited up to about 59% to the amount of intracullular melanin ($IC_{50}=10.85{\mu}g/mL$). The $IC_{50}$ value of ${\alpha}-arbutin$ used as a positive control was $59.99{\mu}g/mL$. So, EtOAc fractions of M. obovata Bark extracts showed whitening effect when compared with the non-treatment group. In case of in vivo study, Cosmetic cream with EtOAc fractions of M. obovata Bark extracts was approved by Ethics committee of KDRI (IRB number: KDRI-IRB-1537). As a result in progress for skin sensitization as well as assessment of skin irritation through repeated patch test, skin allergens was identified as non sensitizing agents. Also, cosmetic cream with EtOAc fractions of M. obovata Bark extracts showed significant topical whitening effect and reliable skin safety when compared with the non-treatment group. In conclusion, EtOAc fractions of M. obovata Bark extracts may be a useful cosmetic ingredient for effective skin whitening.

• Journal of radiological science and technology
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• v.32 no.2
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• pp.177-182
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• 2009

Purpose : This study presents the optimization of flip angle (FA) to obtain higher contrast to noise ratio (CNR) and lower specific absorption rate (SAR). Materials and Method : T1-weighted images of the cerebrum of brain were obtained from 50$^\circ$ to 130$^\circ$ FA with 10$^\circ$ interval. Signal to noise ratios (SNRs) were calculated for white matter (WM), gray matter (GM), and background noise. The proper FA was analyzed by T-test statistics and Kruskal-wallis analysis using R1 = 1- exp ($\frac{-TR}{T1}$) and Ernst angle cos $\theta$ = exp ($\frac{-TR}{T1}$). Results : The SNR of WM at 130$^\circ$ FA is approximately 1.6 times higher than the SNR of WM at 50$^\circ$. The SNR of GM at 130$^\circ$ FA is approximately 1.9 times higher than the SNR of GM at 50$^\circ$. Although the SNRs of WM and GM showed similar trends with the change of FA values, the slowdown point of decrease after linear fitting were different. While the SNR of WM started decreasing at 120$^\circ$ FA, the SNR of GM started decreasing at less than 110$^\circ$. The highest SNRs of WM and GM were obtained at 130$^\circ$ FA. The highest CNRs, however, were obtained at 80$^\circ$ FA. Conclusion : Although SNR increased with the change of FA values from 50$^\circ$ to 130$^\circ$ at 3T SE T1WI, CNR was higher at 80$^\circ$ FA than at the usually used 90$^\circ$ FA. In addition, the SAR was decreased by using smaller FA. The CNR can be increased by using this optimized FA at 3T MR SE T1WI.

• 보존과학연구
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• s.34
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• pp.64-81
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• 2013

It is not easy to define the priority criteria of the need of conservation treatment for stone cultural heritage, although many of them have been treated and restored over the past decade. This study approached the correlation between damage grade and the need of conservation treatment based on damage diagnosis of stone cultural heritage carried out from 2001 to 2005. The number of Third-graded (from First to Fifth-grade) stone heritage in deterioration was the highest among state-designated stone cultural heritage. The Fourth-graded stone cultural heritage (143 in total) was mostly influenced by high physiochemical deterioration, whereas the Fifth-graded ones (61 in total) was dominantly affected by biological colonization. It was estimated that total 211 stone cultural heritage were treated for conservation and restoration from 2002 to 2011. They were usually cleaned (total 134, 26.1%), joined and consolidated, and maintenance works as shelter construction, drainage installation and surrounding cleaning were carried out for some of them. The number of conservation intervention increased with the high deterioration grade, and the case number of metamorphic and sedimentary rocks. By age, the stone cultural heritage in Three-kingdom Period were treated the most, and other heritage in Unified Shilla, Goryeo and Joseon showed an approximate ratio. The stone cultural heritage fallen in the fifth-grade in deterioration demonstrated the highest ratio, approximately 80% of conservation intervention. These results can be used as preliminary data to define the emergency criteria for conservation intervention policy.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.29 no.2
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• pp.238-245
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• 1996

Vertical profiles of $^{210}Po\;and\;^{210}Pb$ were measured for the upper 100 m of water column at six stations in the middle region of the Korean East Sea during March 1993. The distribution patterns of these radionuclides with the water mass and controlling factors on their distributions were also discussed. $^{210}Pb$ activities were generally high at surface water and gradually decrease with depth. Vertical profiles of $^{210}Po$ were relatively homogeneous except for at station E3, where chlorophyll-a concentration was the highest and $^{210}Po$ activity in the upper 30 m was lower than below 50 m. The $^{210}Po$ activities relative to its parent $^{210}Pb$ at all stations were deficient at the upper 30 m, but were excess or nearly equilibrated values below 50 m. The magnitude of $^{210}Po$ deficiency was relatively high at station E3 and E6, where strong thermocline occured. However, $^{210}Pb$ activities showed strong excess in the upper 100 m of all stations, compared with its parent $^{226}Ra$. The residence time of $^{210}Po$ ranged from 1.0 to 7.8 years, and was relatively short at station E3 and E6. The data obtained at the upper 50 m water column during $1992\~1994$, also showed that removal rate constant of $^{210}Po$ and inventories of chlorophyll-a was negatively related. This indicates that the primary production plays an important role in controlling the distributions of $^{210}Po$ at the upper water column of the Korean last Sea in spring. While, inventories of excess $^{210}Pb$ was generally decreasing with increasing density difference between 50 m and 100 m, suggesting that $^{210}Pb$ concentrations in the upper water column were controlled by stability of water column.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.34 no.4
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• pp.389-393
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• 2001

For an effective utilization, quality stability of instant powdered oyster soup made of canned oyster processing waste water (IPSW) was determined. Instant powdered soup from oyster hot-water extracts (IPSE) was also prepared by mixing hot-water extract powder (15 g) with table salt (5 g), cream powder (19 g), milk replacer (12 g), wheat flour (20 g), corn flour (15 g), starch (5 g), glucose (7.5 g) and onion powder (1.5 g). In preparing IPSW, mixed powder from wash water and boiling liquid waste, instead of powder from hot-water extracts and table salt, was added (powder from boiling liquid waste: powder from wash water= 12: 8) and other additives were added in proportion to those in the IPSE. The moisture content, water activity, peroxide value and fatty acid composition showed little changes during storage of the IPSW. The pH, volatile basic nitrogen content and brown pigment formation increased slightly, while white index decreased slightly during storage of IPSW. No significant difference was observed in the changes of food component during storage between IPSW and IPSE. According to a sensory evaluation, the change in quality of IPSW was negligible during 12 months of storage. from the results of the chemical experiment and sensory evaluation, IPSW packed with laminated film bag (OPP, $20{\mu}m/PE,\;20{\mu}m/paper,\;45g/m^3/PE,\;20{\mu}\;m/Al,\;7{\mu}\;m/PE,\;20{\mu}m$) was revealed to be preserved in good quality during 12 months of storage.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.34 no.4
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• pp.340-347
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• 2001

Seasonal variation of the elemental and biochemical composition of the suspended particulate matter (SPM) was investigated in terms of quantity and quality of diets for suspension feeders from July 1999 to August 2000 in two coastal bay systems of Gosung and Kangjin Bays in Korea. No clear patterns in the seasonal variations of SPM concentration were found in these two bay systems. The results indicated that the seasonal variation of SPM could not be considered the variation of food available to suspension-feeders. The simultaneous peaks in chlorophyll a and biochemical components in summer indicated that the quantity of the particulate organic matter primarily depended on phytoplankton productivity. However, no correlation between chlorophyll a and biochemical components [particulate protein (PPr), carbohydrate (PCHO) and lipid] were found, indicating that other processes might also contribute to the particulate organic matter in the period when the phytoplankton biomass was low. High C: Chl a and C:N, and carbohydrate peaks during the autumn to spring period suggested that resuspension of surface sediments was a probable process to supply the particulate organic matter. The food material, represented by summing up the total quantity of three biochemical components, was highest in spring with minor peaks during the period from autumn to the next spring, The food index, calculated as the ratio of food material to total SPM, did not generally exceed $6\%$ with short peaks during the year. Therefore, nutritional quality of SPM in the bays are relatively poor than in other more productive coastal waters in the world. Our results confirm that the measurement of a single chemical variable cannot describe fully the nutritive value of the seston available to suspension-feeders as previously proposed, and the biochemical composition of SPM can provide effective information on its origin and nutritive Quality.

• Journal of dental hygiene science
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• v.11 no.1
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• pp.15-21
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• 2011

Introduction The aim of this study, personal trait and their dental care based on experience level of dental fear is to analyze the differences. Catastrophizing is an irrational belief that something is far worse than it actually is. Because it makes it possible to analyze patients' anxious thoughts and tendencies. Methods The Dental Fear Survey(DFS) and Anxious Thoughts and Tendencies(AT&T) were used as measuring tools, and the independent sample t-test and ANOVA were performed on the basis of the mean value of the summated scale scores and the standard deviation. On the factors to dental anxiety, the multiple regression analysis was performed. Results Demographically, the total DFS score was higher in women($25.73{\pm}8.27$) than in men. Also, AT&T was higher in women($31.01{\pm}7.05$) (p<0.05). Dental fear was intense in the group of patients who visited dental clinics only problems($25.29{\pm}8.57$) than in those regular visited($22.29{\pm}7.78$). In relation to dental experiences, the DFS score was significantly higher in children. In many cases, patients experienced therapeutic pains in children($26.40{\pm}9.54$) (p=0.004). Also in many patients, dental anxiety began to occur in adolescence(44.3%). The multiple regression analysis result, it was found that dental treatment pain and their AT&T wielded great influence upon dental fear.

• Journal of dental hygiene science
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• v.14 no.4
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• pp.516-524
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• 2014

Workers' oral health is important to guarantee workers' right of health and increase productivity. The aim of this study was to investigate recognition and satisfaction of national oral examination for workers in Incheon and Daejeon. Three hundred seventy-nine workers who were selected by convenience cluster sampling answered the questionnaire about experience, recognition and satisfaction of national health examination and oral examination by self recording type. A total of 76.0 percent of the subjects had national health examination, and 51.7% had national oral examination. A total of 64.9 percent had experienced notice about national health examination from the company, and 28.2% about national oral examination. The subjects had high positive score about intention of treatment, dental scaling, and change of toothbrushing method depending on oral examination, need of national health and oral examination, and usefulness to one's health through national health and oral examination. Office workers, regular workers, and the workers with monthly income more than 2 million won had more notice about national health and oral examination compared with sales and production workers, contract workers and the workers with monthly income less than 2 million won. We suggest institutional management of the notice about national oral examination be needed, especially for economically poor, or contract workers to increase the ratio to have national oral examination.

• Journal of dental hygiene science
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• v.7 no.1
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• pp.1-7
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• 2007

This study aimed to provide basic information on dental hygienists' practicing the prevention of infections by figuring out their actual conditions in dental clinics. The subjects of the study were the dental hygienists who participated in the continuing medical education of Incheon & Gyeonggi-do association and Seoul city association in October and November 2005 and the self-administered surveys were used for the prevention of infections. The results were as below. 1. In terms of education experiences of infection prevention, those who answered "there were" were 72 persons (42.9%) and those who followed the educational route for infection prevention were "through the in-house education from the hospital" and they were 42 persons (58%), which were highest. 2. In terms of the injury experiences, those who answered "there were" were 147 persons (87.5%) and the number of annual injury out of 147 persons with injury experiences was 7.7 time. For the tools that were damaged, 125 persons (75%) damaged the "explorer," which was highest. 3. For the experiences of being infected with contagious diseases, those who answered "there were" were 6 persons (3.6%) and there were four persons for "hepatitis B", one person for "rubella" and one person for "TB." 4. The questions with high practice scores were as in the following: "2. I wash my hands after conducting medical examinations (1.86 points)," "7. I always close the lid of a shot of Novocain after doing local anesthesia (1.86 points)" and "20. I separate and collect the wastes and give them to those who treat accumulated materials (1.85 points)". Meanwhile, the questions with low practice scores were as below: "16. I change my medical gowns (doctor wears) once a day (0.24 point)" and "I wash my medical gowns every time after examining patients with contagious diseases (0.52 points)." 5. The question with high knowledge was as below: "1. The contagion during the dental treatment is determined by source of infection, infection methods, infection routes and the host that is prone to infection (0.95 point)" and the question with the lowest knowledge was "5. HBV(hepatitis B) is destroyed after adding 95oC of heat for more than 5 minutes (0.27 points)." 6. The question with the highest organization-related factors was "I am always ready to use a mask, gloves, etc. if necessary" (0.89 points)" and the question with the lowest score was "There is a guideline that I can refer when I am exposed to dangerous situations related to the contagion in my workplace (0.33 point)." 7. In terms of the equipment conditions of protectors in medical environments, 168 persons for (disposable) mask (100%), 167 persons for disposable gloves (Latex) (99.4%), which meant that most of them were equipped with them. On the contrary, 108 persons (64.3%) are equipped with the protectors for frontal faces, which is the lowest and 165 persons (98.2%) said that they had autoclave in their disinfecting and sterilizing devices.

• Journal of Life Science
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• v.19 no.3
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• pp.366-372
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• 2009

In the course of screening of useful enzyme-producing microorganisms from marine sedimentary layers, we isolated 2 amylase producing strains and tested their amylase producing activities. Analyses of 16S rDNA sequences and biochemical methods (BIOLOG) of two isolates showed that they were confirmed to be a gram positive Bacillus sp. and gram negative Pseudoalteromonas sp., respectively. Excellent amylase producing strains were termed Bacillus sp. ST-63 and Pseudoalteromonas sp. ST-140, and further studies were conducted on their amylase producing characteristics. Optimum conditions for cell growth in amylase activity were obtained when the isolate (Bacillus sp. ST-63 and Pseudoalteromonas sp. ST-140) was cultured at $30^{\circ}C$ and pH $7{\sim}8$.