• Title/Summary/Keyword: 과학성

Search Result 35,130, Processing Time 0.058 seconds

A Case of Klinefelter Syndrome with Refractory Seizure in Infant (난치성 경련이 동반된 클라인펠터 증후군 영아)

  • Kim, Sun;Kim, Jong Seok;Kim, Dong Hyun;Lee, Ji Eun;Kwon, Young Se
    • Journal of the Korean Child Neurology Society
    • /
    • v.26 no.4
    • /
    • pp.276-279
    • /
    • 2018
  • Klinefelter syndrome a genetic disorder with various clinical manifestations. Neurological symptoms, such as seizures, are rarely reported with Klinefelter syndrome, and it response well to anti-epileptic drugs. A 5-month-old boy visited the Inha university hospital due to jerking movements and hiccups. The patient had been diagnosed with Klinefelter syndrome at birth and had a medical history of admission to the neonatal intensive care unit due to opisthotonus and ocular deviation at 26 days of age. The patient's serum testosterone level was decreased and his anti-$M{\ddot{u}}llerian$ hormone level was increased. The brain image examination was normal and the electoencephalography and other blood test results showed no specific findings. However, after admission, the patient recurred generalized tonic-clonic-seizures recurred intermittently even after the administration of antiepileptic drugs. This paper reports a case of non-febrile seizures in a child with Klinefelter syndrome who presented with a refractory course.

Development of Primary Reference Gas Mixtures for Liquid Propane (혼합 액체 프로판 표준가스 개발)

  • Jeong, Yun-sung;Kim, Jin-seog;Bae, Hyun-kil;Kang, Ji-hwan;Lee, Seung-ho;Kim, Yong-doo
    • Journal of the Korean Institute of Gas
    • /
    • v.25 no.4
    • /
    • pp.49-56
    • /
    • 2021
  • Liquefied Petroleum Gas is divided into liquefied gases containing propane (C3H8) and butane (C4H10). The quality of LPG varies greatly depending on the composition of the mixture, so it is important to measure the composition accurately. It is difficult to determine the composition of the mixture because liquid and gas coexist at room temperature. Therefore, the uncertainty in determining the concentration of hydrocarbons by component is high, and there are many problems that differ from the actual content standard. Therefore, it is necessary to develop a mixed liquid propane standard gas for the composition and accurate concentration of hydrocarbon substances. Mixed liquid propane standard gas is manufactured into bellows-type constant-pressure cylinders by ISO-6142 (2015). The homogeneity of the four standard gases manufactured was confirmed to be GC-FID. The manufacturer's uncertainty of expansion was 0.01 % to 0.30 % and homogeneity was 0.03 % to 0.25 %. In this mixed liquid propane standard gas, the relative expansion uncertainty of weight method, manufacturing consistency, cylinder adsorption and long-term stability was developed within 0.26 %-1.3 9% (95% of confidence level, k=2).

Exploiting GOCI-II UV Channel to Observe Absorbing Aerosols (GOCI-II 자외선 채널을 활용한 흡수성 에어로졸 관측)

  • Lee, Seoyoung;Kim, Jhoon;Ahn, Jae-Hyun;Lim, Hyunkwang;Cho, Yeseul
    • Korean Journal of Remote Sensing
    • /
    • v.37 no.6_1
    • /
    • pp.1697-1707
    • /
    • 2021
  • On 19 February 2020, the 2nd Geostationary Ocean Color Imager (GOCI-II), a maritime sensor of GEO-KOMPSAT-2B, was launched. The GOCI-II instrument expands the scope of aerosol retrieval research with its improved performance compared to the former instrument (GOCI). In particular, the newly included UV band at 380 nm plays a significant role in improving the sensitivity of GOCI-II observations to the absorbing aerosols. In this study, we calculated the aerosol index and detected absorbing aerosols from January to June 2021 using GOCI-II 380 and 412 nm channels. Compared to the TROPOMI aerosol index, the GOCI-II aerosol index showed a positive bias, but the dust pixels still could be clearly distinguished from the cloud and clear pixels. The high GOCI-II aerosol index coincided with ground-based observations indicating dust aerosols were detected. We found that 70.5% of dust and 80% of moderately-absorbing fine aerosols detected from the ground had GOCI-II aerosol indices larger than the 75th percentile through the whole study period.

Effects of Tiamulin on Starry Flounder, Platichthys stellatus Infected with Streptococcus parauberis HFTC0083 (Tiamulin이 Streptococcus parauberis HFTC0083에 감염된 강도다리(Platichthys stellatus)에 미치는 영향)

  • Joo, Min-Soo;Kim, Boseong;Kim, Do-Hyung;Seo, Jung-Soo;Kwon, Mun-Gyeong;Jee, Bo-Young;Park, Chan-Il
    • Journal of Marine Life Science
    • /
    • v.4 no.1
    • /
    • pp.29-37
    • /
    • 2019
  • In order to control disease caused by multi-drug resistant bacteria in the aquaculture, the use of veterinary antibiotics, which are prohibited to fish, is increasing, instead of the existing fisheries antibiotics. Among them, tiamulin is illegally used in some cultured fish because it exhibits effective antibacterial activity against Gram-positive bacteria. To prevent unauthorized use, treatment of fish should be accompanied by a prescription from veterinarians or fisheries disease managers through research on fish of tiamulin. Tiamulin was injected intramuscularly at 5, 10 and 15 mg kg-1 for the streptococcus-infected starry flounder, but did not show any therapeutic effect. Oral administration at a concentration of 15 and 30 mg kg-1 was similarly ineffective. The concentrations of 30 and 60 mg kg-1 resulted in death due to toxicity of antibiotics. Therefore, it is inappropriate to treat antibiotics with streptococcus-infected starry flounder.

A New Short Stem, Lodging Resistance and High Yielding Vegetable Peanut cultivar, "Jopyeong" (조숙 단경 내도복 다수성 풋땅콩 "조평")

  • Pae, Suk-Bok;Park, Chang-Hwan;Cheong, Young-Keun;Jung, Chan-Sik;Lee, Myung-Hee;Lee, Yu-Young;Hwang, Chung-Dong;Oh, Se-Kwan;Kim, Jung-Tae;Park, Keum-Yong;Kim, Wook-Han;Choi, Gyu-Hwan;Lee, Jae-Chul;Jeong, Byung-Joon;Kim, Ho-Young
    • Korean Journal of Breeding Science
    • /
    • v.40 no.1
    • /
    • pp.63-67
    • /
    • 2008
  • A new peanut cultivar "Jopyeong" (Arachis hypogaea ssp. hypogaea L.) was developed at the Yeongnam Agricultural Research Institute, NICS, in Milyang in 2006. It was developed from the cross between the very short stem cultivar "CUP brittle" and the high-yielding cultivar "Daekwang". "Jopyeong" which is Virginia plant type has 23 branch number per plant with early maturing and ellipse-shaped large kernel. Each pod has two grains with brown testa and 100 seed weight was 87g in the regional yield trials (RYT). This variety also showed more resistant to late leaf spots compared with check one. Especially it has resistance to lodging owing to short stem and erect plant type. In the regional yield trials "Jopyeong" was out-yielded than check variety by 11% with 8.37 ton/ha for fresh pod and by 4% with 3.95 ton/ha for grain.

Study on Waxy Corn IX. Amylogram Properties, Antioxidant Activity and Texture Analysis on the Developed Waxy Corn Hybrids (찰옥수수 연구 IX. 찰옥수수 교잡종의 아밀로그램 특성, 항산화성 및 식미관련 종실의 물성)

  • Bok, Tae-Gyu;Lee, Moon-Sub;Choi, Yun-Pyo;Cha, Hui-Jung;Baek, Seoung-U;Jo, Yang-Hee;Lee, Hee-Bong
    • Korean Journal of Breeding Science
    • /
    • v.43 no.1
    • /
    • pp.62-67
    • /
    • 2011
  • This study was carried out to gain basic informations about amylogram, antioxidant activity function and physicochemical properties for kernel of the newly developed waxy corn hybrids. The used materials were produced in 2008 and cultivated at breeding farm of CNU in 2009. From amylogram analysis, peak and minimum viscosity of the used hybrids were appeared in CNU08H-71 and CNU08H-69 hybrid, respectively. DPPH free radical scavenging effect marked as election donating ability was highly appeared in CNU08H-15 and CNU08H-69 hybrid, while CNU08H-h102 hybrid was the lowest. Hardness of kernel was highly appeared in CNU08H-35 hybrid, and chewiness and gumminess were also the highest in this hybrid, but those of CNU08H-h105 hybrid were the lowest. In these facts, we confirmed that the used hybrids were very different among traits related to amylogram, functions and table qualities. Accordingly, development of the new waxy corn hybrid will be profitable to select and develop as a crossing combination including many excellent traits.

A Clinical Study for the Efficacy and Safety of Functional Cosmetics Containing peptide Scolopendrasin-I isolated from the Scolopendra subspinipes mutilans in Patients with Dry Skin due to Mild Atopic Dermatitis (아토피성 피부로 건조함을 가진 대상자에 대한 왕지네로부터 분리한 펩타이드 Scolopendrasin-I 함유 기능성 화장품의 기능성 및 안전성을 평가하기 위한 임상적 연구)

  • Park, Hye-Su;Kim, Tae-Jun;Park, Shin-Yong;Kim, Hee-Taek
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
    • /
    • v.32 no.3
    • /
    • pp.23-36
    • /
    • 2019
  • Objectives : The purpose of this study is to confirm the efficacy and safety of "Functional cosmetics containing peptide Scolopendrasin-I isolated from the Scolopendra subspinipes mutilans" on dry skin due to mild atopic dermatitis. Methods : A total of 24 patients who visited Semyung Oriental Medical Center from November 1st, 2018 to December 20th, 2018 were included in the study. In this study, the patients were treated with Functional cosmetics containing peptide Scolopendrasin-I isolated from the Scolopendra subspinipes mutilans. For 4 weeks of gross examination, instrumental assessment were made before and after the study to evaluate how well the products for treatment group in recovering the dry skin barriers by mild atopic dermatitis. Results : 1. In the primary endpoint, Skin Hydration showed a statistically significant increase in treatment group in baseline, 2 weeks and 4 weeks. 2. In the primary endpoint, Transepidermal Water Loss(TEWL) showed a statistically significant decrease in treatment group between Baseline and 4 weeks. 3. In the secondary endpoint, Skin pH showed a statistically significant decrease in treatment group between baseline and 4 weeks. 4. To evaluate the safety of the products for the human body, Adverse events, SCORAD Index Assessment were conducted; There were no severe adverse events during this study. And SCORAD Index showed a statistically significant decrease in treatment group in baseline, 2 weeks and 4 weeks. Therefore, it is suggested that products, if used for certain period, should be safe for the human body. Conclusions : According to the above experiments, it is suggested that "Functional cosmetics containing peptide Scolopendrasin-I isolated from the Scolopendra subspinipes mutilans" should be effective for dry skin due to mild atopic dermatitis.

Anti-inflammatory effect of non-thermal atmospheric pressure plasma for periodontitis treatment: in vitro pilot study (치주염 치료를 위한 저온상압 플라즈마의 항염효과: 예비 실험)

  • Park, You li;Kim, Hyun-Joo;Lee, Ju-Youn;Jeong, Sung-Hee;Kwon, Eun-Young;Joo, Ji-Young
    • Journal of Dental Rehabilitation and Applied Science
    • /
    • v.37 no.2
    • /
    • pp.88-94
    • /
    • 2021
  • Purpose: The purpose of this study was to evaluate the anti-inflammatory effects of non-thermal atmospheric pressure plasma (NTP) on human gingival fibroblasts (HGFs) for clinical application of periodontal treatment. Materials and Methods: HGFs were treated with Porphyromonas gingivalis (Pg) lipopolysaccharide (LPS). Customized NTP device was developed for periodontal in vitro study. Cell viability was evaluated with cell counting kit-8. The levels of inflammatory cytokines, including interleukin (IL)-8 and 6, were determined by enzyme-linked immunosorbent assay. Results: When NTP was applied, the cell viability did not change significantly, and there was no difference for 6 h and 24h. When Pg LPS was treated to HGFs, the secretion of IL-8 and IL-6 was increased compared to the control group. But when the NTP was applied, the secretion of them was significantly decreased. Conclusion: NTP did not affect cell viability of HGFs. And it inhibited the LPS-induced production of IL-8 and IL-6.

Development of Building System for Achieving an Optimal Growth Environment in a Vertical Smart Farm (수직형 스마트 팜의 적정 생육환경 조성을 위한 건축 시스템 개발 - 수직형 스마트 팜에 최적화된 내부 공기 균일성 향상에 대한 연구 -)

  • Kim, Handon;Lee, Jeonga;Choi, Seun;Jang, Hyounseung;Kim, Jimin
    • Korean Journal of Construction Engineering and Management
    • /
    • v.22 no.4
    • /
    • pp.3-10
    • /
    • 2021
  • According to the IPCC, humans are influencing the climate system. Such changes in the climate system can cause problems in the supply of food ingredients in the agricultural field by changing the existing growing environment. To solve this problem, vertical farms can be a good alternative for a stable supply of food ingredients. Although the vertical smart farm pays close attention to maintaining and managing the growing environment of crops, it is difficult to uniformly implement temperature, humidity, illumination, oxygen, and carbon dioxide concentrations in the building space. As a result of conducting computational fluid dynamics analysis to ensure air uniformity, a remarkable result is that it is advantageous to continuously spray suitable carbon dioxide CO2 concentrations for a long period of time for air uniformity in a vertical smart farm. Through this result, it is possible to efficiently plan a growing environment system optimized for a vertical smart farm. Based on this study, if efficient crops are produced by creating an optimized growing environment for vertical smart farms, it will be able to contribute to the development of the agricultural field.

A Study on Factors Related to Sleep Disordered Breathing in Children (어린이의 수면 호흡 장애 관련 위험인자)

  • Nawoon, Kim;Daewoo, Lee;Jaegon, Kim;Changkeun, Lee;Yeonmi, Yang
    • Journal of the korean academy of Pediatric Dentistry
    • /
    • v.49 no.2
    • /
    • pp.180-187
    • /
    • 2022
  • The aim of this study was to investigate the risk factors associated with sleep disordered breathing (SDB) by comparing intraoral factors, body mass index (BMI), and medical history with pediatric sleep questionnaire (PSQ) findings. Seven hundred eighty-seven subjects aged between 7 to 11 years old were included. Their caregivers were asked to complete questionnaires. Oral manifestations including Angle's classification, overjet, and Brodsky tonsil grade were examined. Children with PSQ scores of more than 0.33 points were classified into the SDB high-risk group. Among the 787 subjects, 34 (4.3%) were classified into the SDB high-risk group. Children with allergic rhinitis, atopic dermatitis, excessive overjet, or large tonsil size had a significantly higher risk for SDB versus those without. Also, there was a significant difference in SDB risk according to BMI status. Gender, gestational age, breastfeeding, and Angle's classification were not associated with SDB. Children at high risk for SDB were predisposed to tonsillar hypertrophy, allergic rhinitis, obesity, and atopic dermatitis. Children with these factors could be candidates for early intervention to prevent the progression of SDB.