• Journal of Digestive Cancer Research
• /
• 제2권2호
• /
• pp.72-74
• /
• 2014

췌장암은 예후가 매우 불량한 대표적인 암이며, 특히 전이성 췌장암의 경우 생존기간이 3-6개월에 불과하다. 대부분의 췌장암 치료는 항암화학요법이 근간을 이루지만 수술적 치료 이외에 항암화학요법이나 방사선 치료에는 반응이 미미한 것으로 알려져 있다. 저자들은 다발성 혈관 침범과 복강 내 림프절 전이를 보이는 수술이 불가능한 진행성 췌장암에서 젬시타빈 단독 항암화학요법과 고식적 방사선 치료, 그리고 병행한 사이버나이프 추가 치료로 7년 이상의 장기 생존을 보인 증례를 경험하였다. 추적관찰 중 한 차례의 재발과 병발한 원발성 폐암이 확인되었으나, 이 역시 사이버나이프 치료 후 완전 관해를 보인 드문 증례기에 문헌고찰과 함께 보고하는 바이다.

• 한국과학교육학회지
• /
• 제31권4호
• /
• pp.557-566
• /
• 2011

본 연구는 B-1 교과교실제의 실시에 따라 신설된 과학 재량 과목에 대한 학생들의 인식을 조사하여, 교과교실제의 실시 효과에 대해 알아보고자 하였다. 과학 재량 과목은 탐구 실험 수업으로 교과교실에서 진행되었고, 블록타임제와 분반 수업을 적용하여 실시되었다. 교과교실제 수업과 이 과목에 대한 학생들의 인식을 알아보고자 2차례에 걸쳐 학생 설문조사가 이루어졌다. 연구의 결과, 학생들은 교과교실제 수업으로 인해 교사의 수업 준비도, 수업 흥미도가 높아졌다고 생각하고 있었다. 과학 실험 중심의 과학 재량 과목에 대한 만족도는 매우 높았으며(84%), 이공 계열 지망 학생(p<.05)과 성취도 상위권 학생(p<.01)의 경우 유의미하게 높은 만족도를 보였다. 또한 블록타임제와 분반 수업에 대해서도 긍정적으로 인식하고 있었다.

• 대한의사협회지
• /
• 제61권11호
• /
• pp.670-677
• /
• 2018

Many of the patients visit the doctors because of itching sensation. Itching is an unpleasant sensation. In the epidermal keratinocytes, various neurotransmitters and receptors are related itching. The itch signal is mainly transmitted through the lateral spinal ganglion-derived nerve fibers extending to the lower epidermis. Many mediators such as histamine are involved in the itching pathway. It can be helpful in the treatment of patients having itching sensation with a lot of new therapies from the basic medication such as antihistamines. Also, many drugs are currently under study.

• 대한피부과학회지
• /
• 제56권10호
• /
• pp.624-627
• /
• 2018

Allergic contact dermatitis is an inflammatory condition associated with periorbital erythema, edema, and pruritus. The periorbital skin is relatively thin compared with the skin over other facial areas; therefore, it is vulnerable to allergen penetration and may show a variety of cutaneous manifestations. Recently, vision enhancement surgery is a widely performed procedure, and the prevalence of senile cataract and glaucoma is increasing. The prevalence of periocular allergic contact dermatitis is increasing secondary to the growing use of topical ophthalmic medications. Several studies in Korea have reported periocular allergic contact dermatitis secondary to the use of topical ophthalmic medications including latanoprost ($Latano^{(R)}$), fluorometholone ($Tolon^{(R)}$), polymyxin B ($Terramycin^{(R)}$), atropine sulfate ($Atropine^{(R)}$), neomycin sulfate ($Cambison^{(R)}$), and befunolol hydrochloride ($Bentos^{(R)}$), among others. However, ofloxacin ($Effexin^{(R)})$-induced allergic contact dermatitis has not been reported in the domestic and/or foreign literature. We report a case of periocular allergic contact dermatitis secondary to the use of ofloxacin ophthalmic ointment.

• 대한한방내과학회지
• /
• 제43권2호
• /
• pp.320-325
• /
• 2022

Objective: The purpose of this report is to present the effects of integrative cancer treatment (ICT) on a patient diagnosed with glioblastoma multiforme (GBM). Methods: A 71-year-old male GBM patient received ICT from May 14 to October 12, 2021 and concurrently received temozolomide and radiotherapy. The effect on symptoms was evaluated using a visual analog scale (VAS), and changes in tumor size were assessed using magnetic resonance imaging. Results: After treatment, the VAS score for nausea decreased from 5 to 1, and the tumor size also reduced. Conclusion: ICT could be effective in treating GBM patients by reducing the size of the tumor as well as alleviating the side effects.

• Journal of Medicine and Life Science
• /
• 제19권3호
• /
• pp.130-133
• /
• 2022

Several studies have reported a possible link between anti-aquaporin-4 antibody and vitamin B12 deficiency in neuromyelitis optica spectrum disorder (NMOSD). Bilaterally symmetric hyperintense signals on magnetic resonance imaging (MRI) of the posterior columns, called the inverted V sign, are a characteristic feature of subacute combined degeneration associated with vitamin B12 deficiency. We report a patient with anti-aquaporin-4 antibody-positive NMOSD and an inverted V sign on MRI of the spinal cord and address the association between anti-aquaporin-4 antibody and functional vitamin B12 deficiency.

• 대한두경부종양학회지
• /
• 제39권2호
• /
• pp.59-63
• /
• 2023

Epstein-Barr virus positive diffuse large B-cell lymphoma is very rare malignant tumor in thyroid gland. Compared to Epstein-Barr virus negative diffuse large B-cell lymphoma, it tends to have more extranodal involvement, does not respond to chemoimmunotherapy well, and has worse prognosis. We have encountered a patient with Epstein-Barr virus positive diffuse large B-cell lymphoma of thyroid gland in 75-year-old female presenting with aggravating dyspnea and neck pain.

• 대한구강악안면임플란트학회지
• /
• 제22권4호
• /
• pp.220-235
• /
• 2018

Sinus lift procedure is frequently required for the maxillary molar implant placement. Previous studies have demonstrated alveolar ridge preservation (ARP) can maintain the dimensions of ridge height and width. However, there is a lack of studies which evaluated the effect of ARP to avoid sinus lift procedure. Purpose of this study is to describe a method reducing the need of sinus lift surgery by ARP in maxillary molar areas and to assess the feasibility clinically, radiologically and histologically. Ten maxillary molars in ten patients had severe vertical bone resorption with minimal residual bone height. They were considered having the high possibility of the necessity of sinus lift procedure for dental implant after the extraction. After extraction, open healing ARP with deproteinized bovine bone mineral mixed with 10% collagen and resorbable collagen membranes was performed. After sufficient healing, dental implants were placed, and evaluated clinically and radiologically. Histological observation was conducted just before the implantation in one patient. Implants were successfully placed without sinus lift in all ten cases. All the implants were restored with no sign of complications, and patients are now in a close follow-up up to 20 months post-loading. Histological observation showed minimal inflammatory reaction and newly formed bone was substantially noted. The ARP technique has successfully avoided the sinus lift surgeries. It appears that this procedure may improve the simplicity of the clinical process for the clinicians and reduce the discomfort of patients.

• 과학과기술
• /
• 제30권3호통권334호
• /
• pp.80-81
• /
• 1997

국소성 분절성 신사구체경화증(FSGS)의 형성과정에서 신사구체 비대가 어떤 의미를 갖는가를 집중적으로 연구해 과총에서 수여하는 우수논문상을 수상한 서울대 의대 병리학교실 이현순교수. 이교수는 "병리학은 각종 진단을 내리고 또한 병의 원인을 근원적으로 접근할 수 있다는 점에서 매우 매력적인 학문이라고 생각한다"고 했다.

• 과학과기술
• /
• 제30권8호통권339호
• /
• pp.82-83
• /
• 1997

위암 파라핀조직을 이용하여 세포배양없이 염색체변이를 규명하는 연구로 인정을 받고 있는 카톨릭의대 임상병리학교실 한경자교수. 염색체 연구는 살아있는 세포를 이용해왔으나 한교수는 수술을 통해 얻은 죽은 조직으로 연구해 이 분야의 연구 활성화에 전기를 마련해 학계의 기대를 모으고 있다.