• 대한신경과학회지
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• 제36권4호
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• pp.314-317
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• 2018

Focal subarachnoid hemorrhage occasionally presents as transient focal neurologic episodes mimicking transient ischemic attack (TIA). Unless properly diagnosed, it may aggravate cerebral hemorrhage by administering antithrombotic agents. Therefore, clinicians need to be aware that such focal subarachnoid hemorrhage sometimes cannot be detected on noncontrast computed tomography and blood-sensitive magnetic resonance imaging can detect even a small amount of hemorrhage. We describe an 85-year-old woman with focal subarachnoid hemorrhage and possible cerebral amyloid angiopathy who presented transient left arm weakness recurrently, which mimicked TIA.

• 한방안이비인후피부과학회지
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• 제35권1호
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• pp.105-106
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• 2022

• 대한피부과학회지
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• 제56권9호
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• pp.543-547
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• 2018

Wolf's isotopic response is defined as the occurrence of a new skin disorder at the site of another unrelated skin disease that has already healed. In most cases of isotopic response, the initial dermatosis is herpes infection, and the most frequent second dermatoses are granulomatous reactions. Various interpretations of this phenomenon have been attempted. However, the exact mechanism has not been identified yet. Herein, we report a case in which the secondary disease was segmental vitiligo that appeared over the same dermatomes of herpes zoster. A 71-year-old woman presented with well-defined, depigmented patches on the left chest and back. She had been diagnosed with herpes zoster on the same dermatomes and treated with an antiviral agent 3 years ago. Histological examination showed decreased basal melanin pigments and melanocytes. Consequently, the patient was diagnosed with segmental vitiligo based on the clinical and histological findings.

• 우울조울병
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• 제9권2호
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• pp.57-63
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• 2011

Objectives : This study aimed to investigate the prevalence and risk factors of depression within two weeks after stroke. Methods : A total of 362 stroke patients were recruited. Depression (major and minor depressive disorders) was diagnosed by applying DSM-IV criteria. Data on socio-demographic characteristics (age, gender, education, marital state, living state, religion, occupation, income, life event, and social support), stroke severity (NIHSS), disability (BI), stroke hemisphere and location, vascular risk and disease, and previous history of stroke and depression were obtained. Results : Depression was present in 90 (24.9%) patients: major depression 29 (8%) and minor depression 61 (16.9%) patients. In the univariate analyses, depression was associated with older age, higher number of stressful life event, poorer social support, severe disability, anterior stroke location, previous history of stroke and depression. In the multivariate analyses, depression was independently associated with higher number of stressful life events and poorer social support. Conclusion : Depression was common and was determined by premorbid levels of stress and social support in stroke patients at acute stage. More intensive psychiatric care and intervention is needed for the high risk group.

• 대한피부과학회지
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• 제56권9호
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• pp.556-560
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• 2018

Congenital hemangioma (CH) is a fully formed benign vascular tumor at the time of birth and do not proliferate in postnatal life. CH must be differentiated from infantile hemangioma. CH has three subtypes that are recognized based on their natural history: Rapidly involuting congenital hemangioma (RICH), non-involuting congenital hemangioma (NICH), and partially involuting congenital hemangioma (PICH). It is important to distinguish RICH from NICH because RICH spontaneously regresses but NICH does not. Herein, we report two patients diagnosed with RICH and NICH, respectively. We presented the clinical features as well as ultrasonographic and histologic findings to distinguish congenital from infantile hemangioma.

• 우울조울병
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• 제9권1호
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• pp.30-36
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• 2011

Purpose : Anxiety disorder and depressive disorder are often comorbid with each other, and the comorbidity is associated with poorer psychiatric outcome, resistance to treatment, increased risk for suicide, greater chance for recurrence. We aimed to investigate the comorbidity of anxiety disorder in Korea. Method : Subjects were total of 867 depressed patients recruited CRESCEND-K multicenter trial. We used SCID (Structured Clinical Interview for DSM - IV) to find comorbidity of anxiety disorders in depressed patient. Results : Of 867 patients, total 8.2% had anxiety disorder. Proportion of anxiety disorder Not Otherwise Specified was 3.5%, panic disorder was 1.7%, generalized anxiety disorder was 1.1%, post traumatic stress disorder was 0.9%, obsessive compulsive disorder was 0.6%, social phobia was 0.4%. Conclusion : In this study, anxiety disorder in depression were measured at a low comorbidity rate in compare to previous studies. Selection bias, use of antidepressants at registration, severity of depression symptoms, and point of SICD administration seems to have affected these results. It is probable that comorbidity evaluation would be more precise if shorter, structured interviews such as M. I.N.I.-Plus were used during first clinical interview for depression diagnosis.

• 대한피부과학회지
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• 제56권10호
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• pp.645-647
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• 2018

• 대한피부과학회지
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• 제56권10호
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• pp.647-649
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• 2018

• 과학교육연구지
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• 제46권1호
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• pp.40-52
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• 2022

참여형 과학문화 확산의 일환으로 지속되어 온 생활과학교실은 효과적인 학교 밖 체험·탐구 활동으로서 과학의 대중화에 앞장서왔다. 그러나 최근의 코로나19 상황으로 생활과학교실 역시 비대면으로 전환하거나 대면-비대면 교육을 조합할 수밖에 없는 환경이 되었으며, 이러한 교육의 변화가 여전히 학생들의 과학에 대한 관심과 흥미를 제고하는데 효과적인지 검토가 필요한 시점이다. 이에 본 연구에서는 비대면 생활과학교실 프로그램에 참여한 초등학생들의 평소 관심 분야, 과학기술에 대한 인식, 과학에 대한 관심과 흥미, 과학적 역량이 어떻게 변화되는지 확인하고 학생과 학부모들의 인식 차이를 비교함으로써 비대면 생활과학교실의 교육 효과성을 제고하고 향후 운영 방안에 대해 모색하였다. 연구 결과 비대면 생활과학교실 프로그램 참여 이후 학생들은 과학기술 발전이나 미래기술, 환경오염, SNS에 대한 관심 등이 높아지고 게임에 대한 관심이 줄어드는 경향을 보였다. 또한 과학기술 활동에 대한 관심, 과학에 대한 흥미, 과학적 역량도 증가하여 비대면 생활과학교실의 교육 효과를 확인할 수 있었다. 이를 바탕으로 생활과학교실의 학습 주제와 내용 수준을 다양화하고 소외된 학습자들에게 비대면 과학 학습의 기회를 확대하며, 최신 미디어를 활용한 과학콘텐츠 개발과 공유가 필요함을 제언하였다.

• 대한신경과학회지
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• 제30권4호
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• pp.333-336
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• 2012

Berardinelli-Seip congenital lipodystrophy 2 (BSCL2) gene is known to be associated with different clinical phenotypes; Silver syndrome, Charcot-Marie-Tooth type 2 with a dominant hand involvement and distal hereditary motor neuropathy type V (dHMN-V). Up to now, only two heterozygous mutations (N88S and S90L) in BSCL2 have been reported. We identified a N88S BSCL2 mutation in a dHMN-V family with a spastic gait by whole-exome sequencing. To our knowledge, this is the first report of a N88S BSCL2 mutation in Korean patient.