• Journal of Food Hygiene and Safety
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• v.33 no.4
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• pp.316-323
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• 2018

The purpose of the present study was to investigate the effect of Salvia Plebia R. Br. (SP) powder on the antioxidative defense system and oxidative stress in rats which were fed a high fat high cholesterol diet. Accordingly, the rats were divided into four experimental groups which were composed of a high fat high cholesterol diet group (HF), HF diet with 5% SP powder supplemented group (PA), a HF diet with 10% SP powder supplemented group (PB), and a normal group (N). Consequently, the hepatic catalase activity of the HF group was decreased compared to the normal group (N), but it is recorded that of the PA and PB groups were significantly increased. With this in mind, the PA and PB groups resulted in the case of significantly increased activities of hepatic GSH-px and SOD. The hepatic superoxide radical and hydrogen peroxide contents of the PA and PB groups were significantly decreased, as compared to the HF group. The GOT and GPT activities of the PB group were also significantly decreased when thus compared to the HF group. Notably, the carbonyl values contents of the PA and PB groups were significantly reduced compared to the HF group. The hepatic TBARS values in the liver were significantly reduced as measured in the PA and PB groups. These results suggest that the SP powder may reduce the incidence of oxidative damage, by the activation of an antioxidative enzyme in rats fed with high fat high cholesterol diets.

• Journal of the Korean Applied Science and Technology
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• v.34 no.4
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• pp.995-1003
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• 2017

Whitening and anti-oxidant effects were observed in order to investigate the biological activations of Salvia plebeia herb ethanol extracts. No toxicity was found in both B16F10 melanoma cells and Raw 264.7 cells exposed to Salvia plebeia herb ethanol extracts for 48 hour. The extracts showed significant antioxidant activity in cell-free and cell-cultured system. In the DPPH radical assay, it removed dose-dependently DPPH radicals and showed 77.6% at $100{\mu}g/mL$. In the cells, it also significantly removed silica-induced ROS generation and LPS-induced NO production in a dose dependent manner. Using L-DOPA and L-tyrosine as a substrate, tyrosinase activity was inhibited using Salvia plebeia herb ethanol extracts in a dose-dependent manner. The supression occurred to be in the B16F10 melanoma cells, where dose-dependently inhibited Salvia plebeia herb ethanol extracts of $1{\mu}g/M$ ${\alpha}$-melanocyte stimulated hormone-induced melanin production and the inhibitory effect was 30.7% at a concentration of $100{\mu}g/mL$. This suggests that the Salvia plebeia herb ethanol extracts are usable for cosmetic product developments for anti-oxidant and whitening effects.

• Journal of Bio-Environment Control
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• v.26 no.3
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• pp.208-214
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• 2017

This study aimed to determinate the effect of fluorescent light and light-emitting diodes on the leaf morphology, growth and antioxidant capacity of Salvia plebeia. The plants were grown for 56 days after transplanting (DAT) under the fluorescent light (FL) and LEDs (White, Red and Blue (R+B, ratio 2:1), Blue, Red LED) under the same light intensity and photoperiod ($130{\mu}mol{\cdot}m^{-2}{\cdot}s^{-1}$, 12 hours). Leaf length, width and number of Salvia plebeia at the 56 DAT were significantly higher under the FL and red LED, and lower in the RB LED and white LED. The highest fresh and dry weights of shoot and leaf area were observed in the red LED, followed by the FL and blue LED, and the lowest in the RB LED and white LED. After 21 DAT, leaf apinasty symptom was appeared in plants grown under red LED and RB LED. The chlorophyll content was lower in the red LED. The specific leaf weight, the ratio of leaf dry weight to area, was higher in the blue LED, and lowest in the FL. No significant difference in DPPH radical scavenging activity of Salvia plebeia under the different light sources. All the integrated results suggest that the FL light is a proper light conditions for a closed cultivation of Salvia plebeia.

• Fashion & Textile Research Journal
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• v.18 no.3
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• pp.380-386
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• 2016

This study examined the stainability and functionality of cotton dyed with the extract of Salvia Plebia R. Br. as a research preceding the development of health functional materials and fashion products with a healing motif. The CIELAB measurements of the cotton fabric dyed with the extract of Salvia Plebia R. Br. showed 73.32 for $L^*$, 1.7 for $a^*$, and 37.78 for $b^*$, while the Munsell measurements exhibited 2.63Y in color, 7.18 of brightness, and 5.49 of chroma. The degree of staining resulting from color fastness to laundering, and that resulting from color fastness to perspiration (acid and alkaline), as well as the level of color fastness to crocking (wet and dry) all stayed between relatively higher levels of 4 and 5. The fabric dyed also exhibited SPF 50+, an outstanding sun blocking performance. The deodorization rate was also excellent, rising from 97% to over 99% when the time elapsed increased from 30 minutes to 120 minutes. The fabric dyed also showed a 99.6% antimicrobial activity against staphylococcus aureus ATCC 6538, and a 71.4% antimicrobial activity against Klebsiella pneumoniae ATCC 4352. The aforementioned findings indicate that fabrics dyed with the extract of Salvia Plebia R. Br. contain the potential to be developed for use as health-related materials and fashion products that promote healing.

• Fashion & Textile Research Journal
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• v.18 no.6
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• pp.869-877
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• 2016

This study looks into the dyeing properties and functionality of cotton fabrics dyed in both the Spirodela polyrhiza extract and the extract resulting from the mixture of Salvia plebeia R. Br. and Spirodela polyrhiza. Since the UV-Vis Spectrum of the methanol extract of Spirodela polyrhiza shows absorption peaks at 256, 268nm, and 345nm, it can be inferred that the compound that Spirodela polyrhiza contains is a flavonoid. In addition, it can also be presumed that, by analyzing the infrared absorption spectrum of Spirodela polyrhiza, the plant contains flavonoid compounds, just like Salvia plebeia R. Br.. The UV protection factors of the cotton fabrics dyed in both the Spirodela polyrhiza extract and the extract from the mixture of Salvia plebeia R. Br. and Spirodela polyrhiza were 50+, presenting outstanding UV protection factors. The deodorization rate of the cotton dyed in the Spirodela polyrhiza extract was between 30 and 120 minutes, and the rate rose from 92% to 97% as time passed. The deodorization rate of the cotton dyed in the extract from the mixture of Salvia plebeia R. Br. and Spirodela polyrhiza increased from 88% to more than 91%. The result also revealed that overall the fastness of color, including color fastness to washing related to change in color, as well as the color fastness to light of the fabric dyed in the extract from the mixture of the two plants improved, compared to the cloth dyed only in Spirodela polyrhiza extract. Furthermore, the antibacterial activity was also strengthened.

• Korean Journal of Pharmacognosy
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• v.52 no.3
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• pp.186-191
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• 2021

We developed a method to identify and quantify 6-hydroxyluteolin 7-O-glucoside in the powder of Salvia plebeia (PS) using high-performance liquid chromatography coupled with diode array detector (HPLC/DAD) and equipped with reverse-phase INNO C18 column. The analytical method was optimized and validated using novel parameters. The obtained values for the limits of detection and quantification were 3.60 and 10.90 ㎍/mL, respectively. Calibration curve showed good linearity in the concentration range tested (0.00625-0.1 mg/mL, r² = 1.0000), high accuracy (96.2-101.4%), and precision values (RSD ≤ 0.27%). Our analysis support the use of our method for accurately identifying and quantifying 6-hydroxyluteolin 7-O-glucoside from PS in routine analyses and large-scale extraction processes for content determination.

• Journal of the Korean Society of Food Science and Nutrition
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• v.44 no.6
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• pp.791-799
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• 2015

This study was conducted to investigate the effects of water extract from Rosa multiflora and Rosa multiflora complex on lipid metabolism in rats fed a high cholesterol diet. Experimental rats were divided into four groups, which were composed of normal diet group (N group), high cholesterol diet group (HF group), high cholesterol and 5% Rosa multiflora diet group (HR group), and high cholesterol and Rosa multiflora complex diet group (HRC group). Rosa multiflora complex is composed of Duchesnea chrysantha, Salvia plebeia R. BR., and Sasa borealis. The serum triglyceride (TG) content of the HF group was significantly higher than that of the N group, whereas that of the HRC group was significantly lower. Serum high-density lipoprotein-cholesterol contents of the HR and HRC groups were significantly higher than that of the HF group. The serum total cholesterol and low-density lipoprotein- cholesterol contents of the HF group were significantly higher than those of the N group, and especially the atherogenic index of the HRC group was significantly reduced compared to the HF group. The liver TG and total cholesterol contents of the HF group were significantly increased compared to the normal diet group, while those of the HR and HRC groups were significantly decreased compared to the HF group. Fecal total lipid and total cholesterol contents of the HR and HRC groups were significantly increased compared to the HF group. Uridine 5'-diphospho (UDP)-glucuronyl transferase activity of the HR and HRC groups were increased compared to the HF group. Total bile acid contents of the HR and HRC groups were increased compared to the HF group, and that of the HRC group was significantly increased compared to the HF groups. These results suggest that Rosa multiflora supplementation has powerful health benefits due to UDP-glucuronyl transferase activity, bile acid, and lipid metabolism.