• Investigative Magnetic Resonance Imaging
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• v.14 no.2
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• pp.134-138
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• 2010

Parosteal lipoma is a rare benign tumor containing mature adipose tissue having an intimate relationship to the periosteum. Characteristically, this tumor presents as a lipomatous mass adjacent to bone, eliciting variable reactive changes in the underlying cortex. We report a case of parosteal lipoma of the foot. The MR findings consisted of juxtacortical lipomatous mass abutting to bony protuberance, with internal fibrous striations, and osseous reaction in the adjacent bone. By the aid of multiplanar imaging capability, high spatial and contrast resolution of MRI, characteristic features of parosteal lipoma can lead to diagnosis on imaging.

• Polymer(Korea)
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• v.26 no.5
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• pp.680-690
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• 2002

Implantable biodegradable wafers were prepared with pamidronate -loaded poly (L-lactide-co-glycolide) (PLGA, 75 : 25 mole ratio by lactide to glycolide, molecular weight : 20000 and 90000 g/mole) by direct compression method for the sustained release of pamidronate to investigate the possibility for the treatment of bone resorption. Pamidronate-loaded PLGA powders were prepared by means of physical mixing and spray drying with the control of formulation factors and characterized by scanning electron microscope and X-ray diffractometer. The pamidronate-loaded PLGA powders fabricated into wafers by direct compression under the constant pressure and time at room temperature. These wafers were also observed for their structural characteristic, release pattern, and degradation pattern. The release rate of pamidronate increased with increasing their initial loading ratio as well as increasing wafer thickness. The molecular weight of PLGA affects the release pattern : the higher molecular weight of PLGA, the faster release rate. It can be explained that the higher viscosity of high molecular PLGA solution at same concentration tends to aggregate PLGA and pamidronate resulting in unstable pharmaceutical dosage form. This system had advantages in terms of simplicity in design and obviousness of drug release rate and nay be useful as an implantable dosage form for the treatment of aural cholesteatoma.

• Journal of Chest Surgery
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• v.34 no.6
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• pp.506-510
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• 2001

Langerhans\` Cell Histiocytosis(LCH) is a disease of unknown origin, characterized by abnormal proliferation of Langerhans\` cells. Previously, it has been called histiocytosis X, which included eosinophilic granuloma, Hand-Sch ller-Christian\`s disease, and Letterer-Siwe disease. Any organs or tissues such as skin, lymph nodes, bone and bone marrow can be involved. However, LCH of chest wall is rarely reported in our country. We experienced a 18 month old male child, who had osteolytic lesion involving the rib with axillary lymph node metastasis. The tumor was confirmed as LCH after surgery.

• Journal of the Korean Arthroscopy Society
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• v.13 no.3
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• pp.272-275
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• 2009

Extraarticular synovial chondromatosis is a very rare disease which affects the hands, feet, and wrists most commonly. In cases of involvement around large joints, the tissues around knee are usually involved. It arises from tendon sheath, capsular tissue and bursae. It is an idiopathic process in which the synovial cells undergo the metaplasia into cartilage cells. Chondroid matrix of the cartilaginous nodules calcify and ossify to be the osteochondroma. On simple radiograms before calcification and/or ossification of the chondroid tissues the cartilaginous nodules look normal on radiograms. Therefore MRI is needed to establish the diagnosis. We report a case of extraarticular pan-peri-meniscal synovial chondroma around right knee, initially suspected as a ganglion cyst which clinically mimicked a large rounded lesion or a cystic lesion on MRI.

• Journal of the Korean Applied Science and Technology
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• v.38 no.1
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• pp.168-177
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• 2021

The effects of the Perilla frutescens var. crispa and Atractylodes macrocephala Koidzumi mixture on the activities of osteoblast differentiation and the restraint of osteoclast formation were investigated. the Perilla frutescens var. crispa and Atractylodes macrocephala Koidzumi mixture in the human osteoblast "MG-63" cell, was examined in relation to alkaline phosphatase (ALP) activity and alizarin red stains. In order to observe the effects of osteoclasts formation, we analyzed RAW 264.7 cell tartrate-resistant acid phosphatase (TRAP) activity and TRAP stains. In cytotoxicity testing, it was confirmed that apple extract is safe at a concentration of 50 ㎍/㎖ or less. The ALP activity and Bone calcification formation ability were the Perilla frutescens var. crispa and Atractylodes macrocephala Koidzumi mixture had a lower activity than that of control group. However the Perilla frutescens var. crispa and Atractylodes macrocephala Koidzumi mixture significantly reduced activity of TRAP in the RAW 264.7 osteoclastic cell generation and effectively Inhibited the TRAP(+) multinuclear cells. Thus, our results demonstrate that the Perilla frutescens var. crispa and Atractylodes macrocephala Koidzumi mixture enhances the inhibitory activity of bone-resorption in RAW 264.7 cells. In conclusion, the Perilla frutescens var. crispa and Atractylodes macrocephala Koidzumi mixture seem to be effective in the prevention and treatment of bone related disorders.

• The Journal of Korean Academy of Prosthodontics
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• v.60 no.4
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• pp.442-452
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• 2022

Implant-assisted removable partial denture (IAPRD) can be considered as a simple and cost-effective treatment approach for an edentulous patient with anatomical or financial limitations. Recently, it was reported that the application of IARPD with implant supported fixed prostheses covered by the National Health Insurance Service (NHIS) were increasing. This case report describes the treatment of maxillary fully edentulous patient with anterior four-implant-supported fixed prosthesis and distal extension IARPD. This treatment approach may be advantageous over maxillary implant overdentures in some circumstances. The patient was satisfied with improved function and esthetics in the anterior area and financial benefit from the NHIS. Further long-term clinical studies are needed to establish clinical validity of the treatment approach described in this case report.

• Journal of the Korean Society of Radiology
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• v.85 no.3
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• pp.531-548
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• 2024

Developmental dysplasia of the hip is a condition characterized by hip joint instability due to acetabular dysplasia in infancy, necessitating precise ultrasound examination. Legg-Calvé-Perthes disease is caused by a temporary disruption in blood flow to the femoral head during childhood, progressing through avascular, fragmentation, re-ossification, and residual stages. Slipped capital femoral epiphysis is a condition where the femoral head shifts medially along the epiphyseal line during adolescence due to stress, such as weight-bearing. Differentiating between transient hip synovitis and septic arthritis may require joint fluid aspiration. Osteomyelitis can be associated with soft tissue edema and osteolysis. When multiple lesions are present, it is essential to distinguish between Langerhans cell histiocytosis and metastatic neuroblastoma. This review will introduce imaging techniques and typical findings for these conditions.

• Proceedings of the Korean Society of Veterinary Pathology Conference
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• 2001.09a
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• pp.34-34
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• 2001

2001년 7월 6일 항문폐쇄와 기립불능을 보이는 10일령의 홀스타인 자우가 병리학적 진단을 받고자 경북대학교 수의과대학 병리학교실에 의뢰되었다. 이 자우는 경상북도 고령군의 어느 젖소 목장에서 2 산째 자우였다. 임상적 검사에서는 자우의 출생시 항문폐쇄에 따른 수술을 받은 상태였고 포유를 하려고 하였으나 기립이 불가능하였다. 병리학적 진단을 위해 부검을 실시하였던 바, 왼쪽 1∼3 번 늑골의 결손을 관찰할 수 있었으며 결손된 늑골쪽의 견갑골은 변형되어 있었고 왼쪽 상완골도 그 길이가 짧아져 있는 것을 관찰할 수 있었다. (중략)

• The Transactions of The Korean Institute of Electrical Engineers
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• v.63 no.7
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• pp.956-961
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• 2014

Due to the increasing needs of anti-fall device for elderly, it is required to develop the test rigs for fall simulation. The femoral bone model consists of silicone and steel is used as an effective device to simulate falls. In this work, we propose five different femoral bone models and analyse them by using a commercial FEA tool. It has been shown that two kinds of simplified models exhibit the simulated side falls with an error range of ~1% in the impact load of femoral neck compared with full model. Especially, the upper tissue model is found to provide us with the best efficient test environment, attributable to its simple structure.

• The Science & Technology
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• no.8 s.423
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• pp.18-20
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• 2004

한국항공우주연구원 채연석(54) 원장은 어릴 때부터 로켓 만들기에 푹 빠져 있었다. 고교 시절 자작 소형 로켓이 귓가에서 터지는 바람에 고막을 다치기도 했다. 그 시절은 닐 암스트롱이 달에 인류의 족적을 처음으로 남기고, 미국과 옛 소련의 우주개발 경쟁으로 우주선 발사 장면이 연일 방송과 신문지상을 장식하던 때였다. 그것을 보는 소년 채연석의 꿈은 직접 만든 로켓을 우주로 쏘아 올리는 것이었다. 그로부터 30여 년이 지난 지금 채 원장은 한국의 우주기술 개발의 총 사령탑이 되어 있다. 그 자리에서 그는 우주를 향한 꿈을 바느질의 한땀 한땀처럼 엮어가고 있는 중이다. 한국항공우주연구원 원장실에서 만난 채연석 원장의 표정에서는 우주항공 기술의 기반을 쌓느라 영일없는 나날을 보내는 것을 금방 느낄 수 있었다. 채 원장은 2002년말 우주 개발용 로켓의 주류를 이루고 있는 액체연료를 사용하는 로켓을 개발해 발사에 성공하기도 했다. 그 로켓의 길이는 14m, 지름 1m로 우리 나라 독자 기술로 개발한 것이다. 그는 우리 나라가 독자적으로 인공위성을 만들어, 역시 독자적으로 개발한 로켓으로 발사에 성공하면 월드컵 4강 진출보다 더 국가 이미지가 높아질 것으로 내다봤다. 그만큼 우주기술은 극한 기술과 첨단기술을 골고루 필요로 하기 때문이다.