• The Journal of Korean Society for Radiation Therapy
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• v.12 no.1
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• pp.1-7
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• 2000

• The Journal of Korean Society for Radiation Therapy
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• v.5 no.1
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• pp.92-94
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• 1992

• Progress in Medical Physics
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• v.15 no.3
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• pp.156-160
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• 2004

An essential quality assurance (QA) procedure in high dose rate (HDR) remote after-loading brachytherapy is that of the verification of the Ir-192 HDR source positioning accuracy. A number of methods using mechanical rulers or autoradiograph and video cameras have been reported to check the positional error of the Ir-192 source. In this study, the feasibility of a CMOS (Complementary Metal Oxide Semiconductor) PC camera, with a fluorescent screen, was investigated. The agreement between the planned and measured dwell position was better than 1 mm and dwell times better than 0.4 sec. Our results indicate that the CMOS PC camera system could be used as a QA tool for the on-line determination of the source position and dwell time.

• Radiation Oncology Journal
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• v.9 no.2
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• pp.227-232
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• 1991

Authors described the remote afterloading endobronchial brachytherapy (EBBT technique using the microSelectron HDR Ir-192 and the Asan Medical Center experience. Total 28 EBBT in 9 patients were performed since November 1989 and 24 EBBT in 8 patients were emploiyed for palliation and 3 EBBT in 1 patient was treated curatively. Authors observed a significant relief of obstructive symptom with tumor regression in 7 patients out of 8 who were treated palliatively but one of them died of pulmonary congestion in 3 weeks after EBBT One patient with prior therapy of extensive electrocautery expired within 1 day after 2nd EBBT procedure with massive hemorrhage from the lesion. EBBT procedure has been tolerable and can be performed as an outpatient.

• Journal of radiological science and technology
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• v.35 no.4
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• pp.327-333
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• 2012

Purpose: To analyze the correlation between dose volume histograms(DVH) based on organ outer wall contour and organ wall delineation for bladder and rectum, and to compare the doses to these organs with the absorbed doses at the bladder and rectum. Material and methods: Individual CT based brachytherapy treatment planning was performed in 13 patients with cervical cancer as part of a prospective comparative trial. The external contours and the organ walls were delineated for the bladder and rectum in order to compute the corresponding dose volume histograms. The minimum dose in 0.1 $cm^3$, 1 $cm^3$, 2 $cm^3$, 5 $cm^3$, 10 $cm^3$ volumes receiving the highest dose were compared with the absorbed dose at the rectum and bladder reference point. Results: The bladder and rectal doses derived from organ outer wall contour and computed for volumes of 2 $cm^3$, provided a good estimate for the doses computed for the organ wall contour only. This correspondence was no longer true when large volumes were considered. Conclusion: For clinical applications, when volumes smaller than 5 $cm^2$ are considered, the dose-volume histograms computed from external organ contours for the bladder and rectum can be used instead of dose -volume histograms computed for the organ walls only. External organ contours are indeed easier to obtain. The dose at the ICRU rectum reference point provides a good estimate of the rectal dose computed for volumes smaller than 2 $cm^2$ only for a midline position of the rectum. The ICRU bladder reference point provides a good estimate of the dose computed for the bladder wall only in cases of appropriate balloon position.

• Proceedings of the Korean Society of Medical Physics Conference
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• 2003.09a
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• pp.58-58
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• 2003

목적 : 본 연구에서는 C-arm과 CT에 사용 가능한 자궁경부암용 팬톰을 개발하고 이를 이용하여 기존의 필름 방법에 기반한 위치 확인 방법과 CT 재구성 방법의 정확성을 비교 연구하고자 한다. 정확성이 검증된 후에는 두 방법의 장점을 이용하기 위해 CT로 재구성된 좌표를 필름의 좌표로 변환시켜 현재 사용되고 있는 필름에 기반한 근접 치료 계획 시행에 도움을 주고자 한다. 방법 : 자체 제작한 자궁경부암용 팬톰은 인체 등가 물질인 물과 아크릴을 사용하였고, 크게 localizer 부분과 팬톰 부분으로 구성되어 있다. 또한, 실제 자궁경부암 환자의 임상적인 구조를 모사하여 제작하였다. 자궁경부암 치료시 중요 장기인 방광과 직장을 구와 원기둥으로 설계하였고, 고선량율 applicator는 아크릴 판의 흠으로 고정시켜 제작하였기 때문에 CT 촬영시 applicator를 제거한 영상에서도 applicator의 구조가 정확하게 묘사될 수 있도록 제작하였다. 두 시스템에서 재구성된 좌표를 비교하기 위해 각각의 시스템에서의 얻은 재구성 좌표와 팬톰 자체의 localizer와 재구성 알고리즘을 바탕으로 개발된 프로그램을 이용하여 얻은 좌표로 두 재구성 좌표의 비교 연구를 수행하였다. 정확성이 검증되고 장기의 정보가 담긴 CT의 좌표는 자체 개발된 프로그램으로 2 차원의 필름 좌표로 변환되었다. 본 연구에 사용된 모든 프로그램은 ILD 5.5를 사용하여 개발되었다. 결과 : 두 시스템의 좌표 비교 결과 x, y 축은 차이가 2mm 이내로 비교적 정확한 실험 결과를 얻을 수 있었고, z 축의 경우 CT 슬라이드의 굵기에 따라 2mm-3mm 이내의 차이가 있음을 관찰할 수 있었다. z 축을 제외한 좌표의 차이는 획득한 영상에서 컴퓨터로 좌표를 옮기는 localizer 좌표 선택 과정에 발생했을 것으로 예상된다. 또한, 이 검증된 좌표와 개발된 프로그램을 이용하여 우리는 CT의 좌표를 2차원의 필름 좌표로 정확하게 변환할 수 있었다. 결론 : 이 연구로부터 기존의 C-arm 재구성 방법과 CT 재구성 방법의 비교를 통해 각 치료 기기의 신뢰성을 직접 확인할 수 있었으며, 비교를 통해 검증된 CT의 좌표를 필름 좌표로 변환시킴으로서, 각 시스템의 장점만을 결합한 효과적인 치료 계획을 세울 수 있는 가능성을 제시하였다. 또한 물과 아크릴을 사용한 비교적 간단하고 경제적인 방법으로 C-arm, CT 그리고 MRI에 모두 이용 가능한 팬톰을 제작하여 쉽고 정확하게 위치를 확인할 수 있었다. 더 나아가, 본 연구에서 제작된 자궁경부암 팬톰은 근접치료를 포함하여 관련 팬톰 개발에 도움을 줄 수 있을 것으로 예상된다.

• Proceedings of the Korea Contents Association Conference
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• 2013.05a
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• pp.205-206
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• 2013

자궁경부암 근접치료를 시행했던 환자 10명을 대상으로 동일한 처방에 대한 기하학적 특성이 다른 Ir-192선원을 치료계획시스템을 이용하여 선량평가를 비교 분석 해 보았다.

• Radiation Oncology Journal
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• v.21 no.3
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• pp.238-244
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• 2003

Purpose: The Planning of High-Dose-Rate (HDR) brachytherapy treatments are becoming individualized and more dependent on the treatment planning system. Therefore, computer software has been developed to perform independent point dose calculations with the integration of an isodose distribution curve display into the patient anatomy images. Meterials and Methods: As primary input data, the program takes patients'planning data including the source dwell positions, dwell times and the doses at reference points, computed by an HDR treatment planning system (TPS). Dosimetric calculations were peformed in a $10\times12\times10\;Cm^3$ grid space using the Interstitial Collaborative Working Group (ICWG) formalism and an anisotropy table for the HDR Iridium-192 source. The computed doses at the reference points were automatically compared with the relevant results of the TPS. The MR and simulation film images were then imported and the isodose distributions on the axial, sagittal and coronal planes intersecting the point selected by a user were superimposed on the imported images and then displayed. The accuracy of the software was tested in three benchmark plans peformed by Gamma-Med 12i TPS (MDS Nordion, Germany). Nine patients'plans generated by Plato (Nucletron Corporation, The Netherlands) were verified by the developed software. Results: The absolute doses computed by the developed software agreed with the commercial TPS results within an accuracy of $2.8\%$ in the benchmark plans. The isodose distribution plots showed excellent agreements with the exception of the tip legion of the source's longitudinal axis where a slight deviation was observed. In clinical plans, the secondary dose calculations had, on average, about a $3.4\%$ deviation from the TPS plans. Conclusion: The accurate validation of complicate treatment plans is possible with the developed software and the qualify of the HDR treatment plan can be improved with the isodose display integrated into the patient anatomy information.

• 대한방사선치료학회:학술대회논문집
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• 2001.06a
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• pp.8-9
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• 2001

• The Journal of Korean Society for Radiation Therapy
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• v.7 no.1
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• pp.167-175
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• 1995