• Title/Summary/Keyword: 고지명

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Necessity of 99mTc-dimercaptosuccinic acid scan in infants with low grade vesicoureteral feflux (경도의 방광요관역류가 있는 소아에서 99mTc-dimercaptosuccinic acid 신 스캔의 필요성)

  • Koh, Ji Yeon;Koo, Ja Wook
    • Clinical and Experimental Pediatrics
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    • v.49 no.6
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    • pp.648-652
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    • 2006
  • Objective : $^{99m}Tc$-dimercaptosuccinic acid(DMSA) scan is considered to be the most sensitive examination for detection of renal scars. However, because of its high radiation exposure to the kidney and its limited usefulness for patients with low grade vesicoureteral reflux(VUR), some authors have suggested that DMSA scans should be reserved primarily for children with VUR grade 3 and above. The aim of this study was to reevaluate the necessity of DMSA scans as a screening test in infants without reflux or with low grade reflux. Methods : In this retrospective study, 189 infants(mean age : 6.2 months) diagnosed as UTI were enrolled. Voiding cystourethrogram(VCUG), DMSA scan and renal ultrasonography were performed within 1 month of UTI. VUR grade was classified into three subgroups; low grade(grade 1-2), moderate grade(grade 3), and high grade(grade 4-5), respectively. Results : Renal defects were present in 67 of 189 infants, and 82 of the 378 renal units. The incidence of renal defects was significantly correlated with VUR grade(P<0.01); 28 percent without reflux, 38 percent with low grade, 53 percent with moderate grade, 100 percent with high grade, respectively. However, there was no significant differences in incidence of renal defects between the low grade and moderate grade group. Conclusion : In this study, renal defects were found in quite high percentages; 28 percent patients without reflux and 38 percent patients with low grade VUR, respectively. Moreover, there was no significant difference in the incidence of renal defects between the low grade and moderate grade groups. Therefore, DMSA scan should be performed for infants with UTI as a screening test regardless of the presence of VUR.

Phase II Study of Paclitaxel and Cisplatin as Second-line Chemotherapy in Advanced Non-small Cell Lung Cancer (진행성 비소세포폐암에 대한 2차 화학요법으로 paclitaxel과 cisplatin의 제 2상 임상연구)

  • Seo, Yeoung-Tae;Kim, Bong-Seog;Go, Ji-Young;Choi, Dong-Suk;Choi, Seong-Ho;Kim, Hye-Jin;Ahn, Young-Mi;Roh, Yong-Ho;Lee, Kyung-Hee
    • Journal of Yeungnam Medical Science
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    • v.21 no.2
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    • pp.198-206
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    • 2004
  • Background: To evaluate the efficacy and safety of paclitaxel and cisplatin against advanced non-small cell lung cancer (NSCLC) as a second-line chemotherapy. Subjects and Methods: Twenty-five patients were enrolled. The patients received 200 $mg/m^2$ paclitaxel as a 3-hour intravenous infusion and 60 $mg/m^2$ cisplatin as 2D-minute intravenous infusion with vigorous hydration on day 1 every 28 days. The response was assessed every 2 cycles. Results: All 25 patients were assessed for their response and toxicity. Partial responses were observed in 5 patients. The overall response rate was 20%(95% confidence interval, 4%-36%) and the median response duration was 4.5(range, 2-11) months. The median time to progression was 3.3(range, 0-14) months. The median overall survival of all patients was 7.4(range, 1.3-39) months. The hematologic toxicities were minor and easily controlled. Conclusion: The combination chemotherapy of paclitaxel and cisplatin as a second-line treatment has a moderate efficacy with an acceptable toxicity in patients with advanced NSCLC.

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A study on Blood pressure and Blood constituents of middle-Aged men Obesity (중년 남성 비만의 혈압 및 혈액 성상에 관한 연구)

  • 이현옥;박혜순;승정자
    • The Korean Journal of Food And Nutrition
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    • v.9 no.4
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    • pp.366-371
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    • 1996
  • The purpose of this study was to investigate blood pressure and blood constituents in middle-aged men obesity. All the measurements were taken from 1524(obese 453, control 1071) man's subjects. The body mass index BMI in obese group and control was 26.6$\pm$1.4kg/$m^2$ and 22.2$\pm$1.9kg/$m^2$ respectively. The mean systolic and diastolic blood pressure in obese group were significantly higher than control(p<0.001). The concentrations of serum total cholesterol, triglyceride, HDL-cholesterol, LDL-cholesterol and atherogenic index in obese group were 202.1$\pm$34.7mg/dl, 210.0$\pm$121.8mg/dl, 43.4$\pm$10.3mg/dl, 116.7$\pm$33.5mg/dl, 3.8$\pm$1.2, respectively. There was significance in the relation between cholesterol, triglyceride, LDL-cholesterol and BMI. The frequency of dyslipidemia (hypercholesterolemia and hypertriglyceridemia) in obese group was significantly more than control(p<0.001).

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Human and Animal Study on the Natural Food for Obesity and Metabolic Syndrome Risk Factors (비만 및 대사성증후군 위험인자에 대한 천연물 식품의 인체 및 동물 효능연구)

  • 문근아;최선미;김선형;김성수;강지연;윤유식
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.32 no.8
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    • pp.1394-1400
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    • 2003
  • In this study a natural composition containing oriental herbs, KSH28, for reducing obesity and metabolic syndrome was constructed and its efficacy was evaluated in animal and human. To investigate the anti-obesity effect of KSH28, animal study was conducted using high fat diet-induced obese mice. KSH28 significantly decreased body weight and adipose tissue in high fat diet-fed obese mice. The mean size of fat cells in adipose tissue was significantly reduced. Glucose and triglyceride levels were also significantly decreased. To elucidate its efficacy in human, a natural food containing KSH28 with grains, vegetables, vitamins, minerals and dietary fibers was constructed and 40 subjects (8 male and 32 female) were tested for the change of body composition, blood pressure and blood lipid profile. All subjects had 2 pack (309 each) of natural food per day for 4 weeks. Compared to the baseline value, body fat was significantly reduced, however, water, protein and mineral contents in the body were not changed, suggesting selective reduction of fat tissue. Blood pressure and serum lipid profile were significantly decreased to reduce risk for metabolic syndrome. Serum GPT, a liver function indicator, was not changed and no significant side effects were detected. Therefore, it was shown that the KSH28 is a safe and effective composition for reducing obesity and metabolic syndrome.

Biochemical Analysis of Crew's Blood and Urine before & after Long-Term Navigation (원양항해 전과 후 선원의 혈액 및 소변의 생화학적 분석)

  • Ha Hae-Dong;Moon Serng-Bae;Jun Seung-Hwan;Jeong Eun-Seok;Kim Jae-Ho
    • Journal of Navigation and Port Research
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    • v.30 no.5 s.111
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    • pp.415-420
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    • 2006
  • Urinalyses have been conducted for 28 crew's in H University's training ship and creatine and uric acid turned out to be higher in all ages, which can be inferred that board job has caused negative impact on kidney and/or malfunction In addition, TC and HDL-C, LDL-C ha; decreased, however, TG has increased after the navigation. All different positions including officer, crew, decker, engineer and radio part showed the similar pattern TC and HDL-C has decreased in 30s, 40s and TG has increased in 30s. A few of the 30's show extremely high TG rates so hyperlipidemia is suspected. 7 members turned out positive for UBG test and 5 positive for PRO test. Especially there was only one UBG positive before the navigation but, 7 members has become positive, which means the one-month long-tenn navigation has definite impact on the liver cell function.

Prevalence and Risk Factors of Gallstones in Adult Health Screening Population (건강한 성인의 담석 유병률과 위험인자)

  • Lee, Mi-Hwa;Kwon, Duck-Moon;Cho, Pyong-Kon
    • Journal of radiological science and technology
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    • v.37 no.4
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    • pp.287-294
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    • 2014
  • Gallstone is the most common disease of the biliary system. Korean has experienced an increase in the percentage of cholesterol gallstones. The major risk factors associated with cholesterol gallstones are age, gender as well as obesity. This study was designed to determine the prevalence of gallstones in the last three years and evaluate the associated risk factors in the population who underwent health screening. The study population consisted of 2,484 males and 2,212 females who visited the health promotion center in Dalseogu, Daegu in Korea from January 2011 to December 2013. Each participant in the study had their biliary system gallbladder examined using ultrasonography. Classified as underweight, normal weight or overweight using the population of obese according to the body mass index, and classified according to mood diagnosis of diabetes presented by the American Diabetes Association. Fasting blood glucose and number of liver function, the divided the control group by referring to the normal liver function values used herein. The geological map, I was classified as NCEP APT III. A showed of total 148 people were found to have gallstones. The prevalence of sex among 148 patients (3.15%) 84 men (1.79%) and 64 women 1.36%) which shows significantly there is little difference. 1.84% 40 years and below, 3.38% 40's showed age prevalence was 4.66% in 50's and above. In addition, Total-cholesterol was at the most in 52 people, LDL-cholesterol in 398 people, Triglyceride in 36 people, HDL-cholesterol in 19 people. The abnormal group, was created from the total-cholesterol categories from a physical examination of a subject that has been found to be gallstones in the gallbladder. A result of conducting the univariate analysis shows the prevalence of gallstones, a correlation that is meaningful. The logistic regression analysis of multiple ages was chosen to show risk factors age independent cholelithiasis. In spite of the conclusion, gallstones are not displayed in relation to the metabolic syndrome but in order to clarify this, not only the subject of a health examination is needed but, a further study of the general public when possible.

A Study on the Characteristics of Humanistic Landscape in Pyongyang Castle through Pictorial Maps in the Late Joseon Dynasty (조선후기 회화식 고지도를 통해 본 평양성의 인문경관 특성)

  • Kim, Mi-Jung;So, Hyun-Su
    • Journal of the Korean Institute of Traditional Landscape Architecture
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    • v.38 no.2
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    • pp.14-30
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    • 2020
  • This study focuses on the fact that pictorial maps in the late Joseon Dynasty were conceptual diagrams with the place names perceived by the people at the time of their production. In this regard, targeting on five pictorial maps, the humanistic landscape characteristics of Pyongyang, which had cultural identities such as a historically old, commercial, and Pungnyu(appreciation for the arts) city, were derived as follows. First, the historic legitimacy of Pyongyang Castle was represented by ritual and religious facilities. They include 'Dangunjeon' and 'Gijagung' related to the nation founder, 'Munmujeong': the remains of Goguryeo, 'Sajikdan' & 'Pyongyanggangdan': the place of the national rites, Hyanggyo and Seowon: education & rite functions, Buddhism and Taoist facilities, 'Yongsindang', 'Sanshindang', and 'Jesindan': folk religion facilities. Gija-related facilities, which became symbols of Pyongyang due to the importance of Small-Sinocentrism and Gija dignity tendency, were distributed throughout Pyongyang Castle though, the facilities related to King Dongmyeong of Goguryeo and the spaces of religion praying for blessings are spread in Bukseong and on the riverside of Daedonggang each. Second, as a Pyongando Province's economic center, Pyongyang's commercial landscape was represented by logistics and transportation facilities. The Daedonggang River, which was in charge of transportation functions, had many decks such as 'Yangmyeongpo', 'Cheongryongpo' and 'Waeseongjin' and bridges, such as 'Yeongjegyo' and 'Gangdonggyo', which connected major transportation routes. The road network was created in Oeseong area to facilitate logistics transportation and management, and many warehouses named after the jurisdiction of Pyongyangbu were distributed near the roads and Provincial Offices of the main gates. In addition, it was characterized by the urban area systematically divided with hierarchical roads, 'Bukjangnim' of willow trees planted on the main entrance roads of Pyongyang Castle, a linear landscape created by 'Simnijangnim' consisting of mixed forests with elm trees. Third, Pungnyu City is realized by the distribution of amusement facilities. The riverside of Daedonggang adjacent to Naeseong exhibits characteristics of artificial landscape such as a canal leading to the inside of the castle, a docking facility with embankments, and a port with cargo ships anchored. However, Bukseong of the natural surroundings had numerous pavilions and platforms such as 'Bubyeongnu', 'Eulmildae', 'Choeseungdae', 'Jebyeokjeong' and engraved letters such as 'Cheongnyubyeok', 'Jangbangho'. 'Osunjeong', 'Byeogwolji', 'Banwolji' near 'Sachang', and 'Aeryeondang', built on the island of a square pond, created waterscape in Naeseong invisible from the Daedonggang, and for practical purposes, ponds and repeated willow vegetation landscape related to Gija were placed in the western rampart of Jungseong. In addition, 'Seonyeondong', a cemetery of Gisaeng, located near by Chilseongmun, was used as poem titles and themes by literary people, contributing to the creation of the Pungnyu image of Pyongyang.

The Relationship of Abdominal Obesity and Lipid Profiles by Computed Tomography in Adult Women (전산화 단층촬영을 이용한 성인여성의 복부비만과 지질대사지표와의 연관성)

  • Kim, Mi-Young
    • Journal of radiological science and technology
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    • v.31 no.1
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    • pp.33-39
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    • 2008
  • Abdominal obesity, especially, visceral obesity is thought to be a risk factor of type 2 diabetes and cardiovascular disease such as hypertension, hyperlipidemia, coronary artery disease. Based on previous studies visceral fat accumulation is highly related to these diseases compared to subcutaneous fat accumulation. The purpose of this study was to see the relation between abdominal obesity and lipid profiles in adult women. The included subjects were 25 adult women(BMI > $23\;kg/m^2$), who visited the obesity clinic in a general hospital from April 2006 to September 2007. Blood pressure, fasting glucose and lipid profiles were measured. The abdominal fat distribution had been assessed by CT scan at the level of L4-L5. From bivariate analyses, the visceral fat accumulation showed negative correlations with TC and TC/HDL. The BMI, total abdominal fat and Visceral fat/Subcutaneous fat ratio showed significant correlations with visceral fat accumulation. From linear regression analyses of all the study subjects, TC, TG and HDL were found to be determinants of the visceral fat accumulation($R^2\;=\;0.474$).

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담배연기 없는 맑은 화성 만들기 사업 평가

  • Lee, Hye-Gyeong;An, Mi-Yeon;Lee, Mi-Yeon;Go, Ji-Yeon;Lee, Ji-Seon;Go, Seung-Deok;Park, Nam-Su;O, Eun-Hwan
    • Proceedings of The Korean Society of Health Promotion Conference
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    • 2009.05a
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    • pp.87-87
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    • 2009
  • 2008년부터 화성시에서는 담배연기 없는 맑은 화성 만들기 사업에 착수하였다. 이는 흡연으로 인한 사망 및 질환 유병의 감소, 간접흡연에의 노출, 감소 개인행위 통제를 위한 역량 강화, 지역사회 협력체계 구축 및 지원적 환경의 조성을 목적으로 하고 있다. 포괄적 흡연통제프로그램 모델을 기반으로 하여 각기 적합한 환경을 위한 수행전략과 실행계획을 수립하였다 ; 담배연기 없는 환경조성, 홍보 및 캠페인, 금연클리닉을 통한 교육, 상담의 금연프로그램 운영, 모니터링과 평가, 사업관리를 위한 지침과 교육 등. 2008년 1년 동안 총 1714명이 금연클리닉을 방문하였으며, 이중 90%는 금연시도 4주간, 57%는 6개월 동안 금연상태를 유지하였다. 6개월 동안 금연상태를 유지한 대상 중 67%는 50세 이하 연령이었으며, 6개월 동안 금연상태를 유지한 대상 중 28%에게는 행동수정요법을 적용하였다. 금연환경 조성을 위해 지역사회내 건물과 시설을 모니터링하였으며, 경로당, 유치원, 초등학교, 문화재 등과 같은 특정 환경에 초점을 맞춘 교육과 관리를 수행하였다. 또한 2009년 사업추진방향설정을 위해 지역사회주민들 대상으로 하는 금연정책에 대한 전화조사를 실시하였다. 건강한 도시를 구축하기 위해서는 모든 지역사회구성원을 대상으로 하는 다양하고 효과적인 프로그램을 지속적으로 추진하는 것이 필요하다. 특히 학생, 가족, 학교, 지역사회와 정부간의 담배 없는 화성을 만들기 위한 협력적 관계 구축이 무엇보다 중요하다고 할 수 있다. 향후 보다 나은 사업추진을 위해 현상황에 대한 분석을 토대로 적절한 전략을 개발하는 것이 필요하다.

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Disc and underwriting - A proposal of life underwriter in terms of insurance benefits - (디스크질환과 언더라이팅 -보장급부를 중심으로 고찰한 생명보험 언더라이터의 제안-)

  • Byun, Hye-Jin
    • The Journal of the Korean life insurance medical association
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    • v.27 no.2
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    • pp.96-106
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    • 2008
  • Herniate disc disease is one of the biggest problem in claim of insurance as well as in medical. Herniate disc disease have recently increased, and it is ranked 8th in claim reasons recently. As an underwriter and physical therapist, I want to study interrelationship of insurance and disc disease. I think it is necessary to know about knowledge of medical, so this study is given some space to structure of spine, cause of herniated disc disease, role of disc, methods of classification of disable (McBride method and AMA method), and spine disability stage. disc surgery is divided laparoscope disc surgery and spine surgery. I analysis it some factors- gender, age, occupation, re-surgery, and state of after surgery - through searching medical papers. I suggest below conclusion to underwriter because it can be useful to make questionnaire, and underwriter can expect prognosis. conclusion The negative factors of disc surgery (compare to other cases) were as follows: 1. endoscope disc surgery: $20{\sim}40year$ old man, hospitalization period more than 5 days. 2. spine surgery: $45{\sim}70year$ old woman, hospitalization period more than 15 days. 3. re-surgery experience: exist 4. working condition: a person who draws a small income, non-regular worker, working period is less than 1 year. 5. method of surgery: pedicle screw fixation. spine fusion surgery, artificial disc surgery. 6. post surgery condition: appearance of muscle weakness, paralysis, reference pain, lordosis, kyphosis, and complication. smoker or take a drink.

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