• Journal of The Korean Society of Inherited Metabolic disease
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• v.14 no.2
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• pp.142-149
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• 2014

Purpose: There are 15 types of Glycogen storage disease (GSD) that have been identified, and GSD type Ia is the most common type. There are several studies of Korean GSD type Ia patients' long-term complications. The aim of this study to find out clinical symptoms and prognosis of GSD type Ia patients. Methods: We performed clinical, biochemical and genetic analysis retrospectively on five patients diagnosed with GSD type Ia in a Soonchunhyang University Hospital from July 2002 to July 2014. Results: All patients had hepatomegaly at diagnosis, and they were all confirmed to have fatty liver at abdomen USG. They had no developmental delay, but two of them had growth retardation. Elevated blood lactate, triglyceride, and uric acid levels can find out all patients, but only one patient had hypoglycemia. They are diagnosed with GSD through gene analysis, and by gene analysis, they have c.648G>T (homozygote, splicing mutation), c.122G>A/c.648G>T, c.248G>A/c.648G>T mutations. Treatment with three times meals, three times snacks and four to six times use of uncooked constarch for all patients. Following the progress, one of them resulted in hypothyroidism, other one had renal stones. A patient diagnosed at 16 years old had liver cirrhosis and started having hemodialysis for ESRD. Conclusion: GSD type Ia patients had hepatomegaly, hyperlipidemia, hyperuricemia, and lactacidemia. Therefore patients who have such these symptoms are recommended gene analysis. A patient diagnosed at 16-years-old had liver cirrhosis and ESRD in progress, early diagnosis and treatment are important for GSD type Ia patients.

• Korean Journal of Childcare and Education
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• v.11 no.1
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• pp.501-521
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• 2015

This study aims to examine the effects of the main eight items amended in the 2013 child care center accreditation system and to provide suggestions. The participants in the study were 200 child care center teachers and staff; 150 professionals consisting of public officials in charge of child care, members for the accreditation committee, and inspectors at the site; and 144 parents. They participated in an on-line questionnaire survey conducted during the end of February, 2014. The survey questions regarding the eight changed items were the same to all the three participating groups, and three more questions were asked to child care center teachers and staff. The collected data were analyzed with frequencies and percentages to present general recognition level. For a group comparison, analysis of variance was first performed among 3 professional groups, all of which has the same size. When there was not a statistically significant difference among the three groups, the second analysis of variance was done among three groups of professionals including the three groups, teachers and staff, and parents. The results showed that there were differences in recognition among the groups regarding each changed item in the 2013 child care center accreditation system, but overall, the groups evaluated the main amendments positively and the changes were considered appropriate and necessary. However, it was found that in-depth reviews are needed of procedure unification to check the basics to require legal compliance; management of unaccredited centers such as valid period reduction and no accreditation, or limit for re-accreditation application; and the burdens of child care centers about surprise visits and notice of inspection dates in advance.

• Journal of the Korea Convergence Society
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• v.11 no.10
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• pp.133-138
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• 2020

The purpose of this study was to identify malignant tumor-related factors in breast diseases and to find out how recently reported oral contraceptives affect women in Korea. The research method is data from the 7th National Health and Nutrition Survey conducted by the Korea Centers for Disease Control and Prevention, and was provided according to the procedures for use guided through the website of the Korea Centers for Disease Control and Prevention. The analyzed data covered a total of 9,981 people, 3,341 in 2016, 3,263 in 2017 and 3,377 in 2018. The results from the study showed the significance of age, smoking, drinking, hyperlipidemia and unmarried related variables, especially the significance of oral contraceptives. Based on this study, it can contribute to active prevention of related factors and cancer-causing suppression policies, especially since the use of oral contraceptives is on the rise, it is believed that continuous research of the subjects to be taken, such as the period and dosage, should be carried out.

• Journal of the Korean Data and Information Science Society
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• v.24 no.4
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• pp.867-876
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• 2013

Metabolic syndrome has been known as a major factor of cardiovascular disease. Several metabolic disorders, particularly chronic disease is complex, and from individuals that appear in our country, the prevalence of the metabolic syndrome is increasing gradually. Therefore, this study, using a multi-factor dimensionality reduction method, checks the major single risk factor of metabolic syndrome and suggests a new diagnosis results of metabolic syndrome. Data of 3990 adults who responded to all the questionnaires of health interview are used from the database of the 5th Korea national health and nutrition examination survey conducted in 2010. As the result, the most dangerous single risk factor for metabolic syndrome was waist circumference and the most dangerous combination factors were waist circumference, triglyceride, and hypertension. This is the result of a new diagnosis of the metabolic syndrome. Especially, waist circumference, low HDL-cholesterol and hypertension were the most dangerous combination for male. In particular, the combination of waist circumference, triglyceride and diabetes was dangerous for obese people.

• Journal of the Korea Convergence Society
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• v.12 no.5
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• pp.385-392
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• 2021

This study conducted to provide the evidence to prevent and promote Metabolic Syndrome by figuring out the relationship between diagnostic indicators and health behavior of participants with Metabolic Syndrome. The subject included 633 participants who visited to university medical center or public health center in Daejeon from July 2017 to July 2018 for regular check-up. The data were analyzed using independent t-test, ANOVA, Scheffe test, Pearson's correlation coefficients by SPSS/WIN 22.0 program. As a result, 633 participants showed the differences in health behaviors according to age, religion, level of education, and the number of diagnostic indicators. By types of metabolic syndrome based on "hyperglycemia", there was a difference in stress management between groups. Moreover, in the group with hyperglycemia, hyperlipidemia was associated with stress management among health behaviors. Therefore, it is necessary to provide an interventional program that include these factors to improve Metabolic Syndrome.

• Korean Journal of Pharmacognosy
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• v.40 no.1
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• pp.51-58
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• 2009

The anti-hyperlipidemic effects of an ethyl acetate fraction from Orostachy japonicus in a high lipid diet-induced hyperlipidemic rat model were assessed. The fraction, which contained kaempferol, astragalin, and isoquercitrin, was associated with significant weight loss and reduction of lipid contents in serum and liver tissues. The fraction, which contains mainly flavonoids, diminished the levels of malondialdehyde and hydroxyl radical, and increased the anti-oxidative enzyme activities of superoxide dismutase, catalase, and glutathione peroxidase. Reduced bleeding and plasma clotting times resulting from the administration of the ethyl acetate fraction may reduce cardiovascular disease associated with hyperlipidemia.

• Journal of Korea Technical Association of The Pulp and Paper Industry
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• v.29 no.1
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• pp.43-51
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• 1997

The various culture conditions of Trichoderma viride(ATCC 3454) and Phanerochaete chrysosporium(ATCC 26921) with glucose-pepton medium, Mandels medium, YMG medium for wood degradable enzyme were examined. Mycellium of the two species grew profusely on glucose-pepton medium. Maximum fungal growth was observed about 10days. But CMCase, Fpase, laccase activity in the culture medium with glucose-pepton was not detected. When grown in fermenter culture using Mandels medium, Trichoderma viride produced CMCase and Fpase. Its CMCase activity was 0.15 lU/ml and Fpase activity was 0.3 IU/ml within about 4-6days. Phanerochaete chrysosporium grown in a YMG medium gave the best enzyme activity when they were grown under stationary culture with an atmosphere of 100% oxygen. Levels of laccase activity of 3.0 mull were achieved in stationary culture under 100% oxygen. The enzyme condensation by ultrafiltration method caused a 2-fold(cellulase) and 6-fold(laccase) as compared to control activity.

• 건강소식
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• v.32 no.3 s.352
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• pp.6-13
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• 2008

뇌졸중은 우리나라에서 발생하는 사망원인 중 두 번째를 차지하는 질병이다. 2003년 통계청 자료에 의하면 연간 10만명 당 뇌졸중으로 인한 사망자는 75.5명에 이르는 것으로 알려져 있다. 하지만 가장 높은 사망원인인 암이 위암, 폐암,간암 등 모든 암 질환을 포함한 것임을 감안할 때 단일 질환으로는 뇌졸중이 사망원인 1위라 하겠다. 성인의 경우 여러 가지 신체적 장애를 일으키는 주범이기도 한 뇌졸중은 주로 노인질환으로 인식되어 왔지만 최근에는 30∼40대에도 흔히 발병하고 있다. 이는 식생활 변화 및 운동부족으로 인해 뇌졸중의 주요 원인인 고혈압, 고지혈증, 당뇨, 비만 등의 발생률이 높아졌기 때문이라 할 수 있다. <건강소식>이 마련한 연간 특별기획 '한국인의 10대 질병부담, 그 예방과 극복'. 이번 달은 그 두 번째 연재로 뇌졸중에 대해 알아보도록 하겠다.

• Journal of the Korean Society of Food Science and Nutrition
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• v.37 no.12
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• pp.1583-1588
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• 2008

The purpose of this work was to study the relationships between dietary intake and serum lipid profile in 293 adult subjects (mean age: $45.9{\pm}0.7$, men: 163, women: 130) who visited health promotion center. The anthropometric and biochemical blood indices were measured, and nutritional intakes were assessed using a food frequency questionnaire method. The subjects were divided by three groups in accordance with a standard for treating hyperlipidemia; those who had blood cholesterol levels above 240 mL/dL or triglyceride levels above 200 mL/dL were put into the risk group (Risk), while those with blood cholesterol levels below 200 mL/dL and triglyceride levels below 150 mL/dL were put into the control group (Control). Subjects who were between the two groups in terms of blood cholesterol and triglyceride levels were put into the borderline group (Borderline). Risk group showed significantly higher body mass index, body weight, waist circumference, and fat content compared to control group. The levels of calorie, carbohydrate, fat, and protein intake were significantly higher in the risk group than control group. There were significantly positive correlations between dietary calorie, carbohydrate, fat, and protein intake and blood triglyceride concentration. The blood HDL-cholesterol concentration had negative correlation with carbohydrate intake. These results suggested that overeating may be one of important factors affecting hyperlipidemia in Korean adults.

• Journal of Sasang Constitutional Medicine
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• v.11 no.2
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• pp.209-226
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• 1999

In this study, we compared the effect of the Therapeutic Diet and Constitutional Diet on the subjects whose total number is 65 and has hyperlipidemia by checking the serum lipids 3weeks later, 6weeks later. In the Taeumin, there is a little difference in the two Dietary Therapies. Therapeutic Diet shows significant decrease in the total-cholesterol(6weeks later), triglyceride(6weeks later). (P<0.05) In that point Therapeutic Diet shows better effect than Constitutional Diet. Constitutional Diet shows better effect in the phospholipid by significant decrease in the phospholipid(6weeks later).(P<0.01) In the Soyangin group, Therapeutic Diet shows no difference, but Constitutional Diet shows significant decrease in the total lipid(3weeks, 6weeks later), phospholipid(3weeks later).(P<0.05).