• Proceedings of the KAIS Fall Conference
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• 2011.12b
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• pp.660-663
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• 2011

우주방사선이나 과도펄스(Transient Radiation) 형태의 감마 방사선이 반도체에 조사되면 소자 내부에서 짧은 시간에 다량의 전하가 생성된다. 이 전하들과 증폭된 과전류는 소자의 고장(Upset, Latchup)과 오동작을 유발시키게 되고 나아가 전자부품이 소진(Burnout)되는 직접적인 원인이 된다. 본 연구에서는 이러한 핵폭 방출 과도방사선에 대한 전자부품/장비의 내방사선관련 기초연구로 군전자부품의 감마-과도방사선에 대한 피해분석 시험을 수행하고 나아가 과도방사선 방호기술 체계구축의 필요성에 대해 논하였다. 과도펄스 방사선시험은 군용으로 분류된 반도체 칩을 대상으로 포항 전자빔가속기를 사용하였다. 핵폭발 방출 과도방사선을 모사하기 위해 감마선 변환장치를 MCNP 설계를 통해 제작하고 단일모드의 마이크로초 단위 감마펄스 방사선을 방출시켜 시험대상 칩을 부착한 시험보드에 조사하는 과정으로 실험을 진행하였다. 온라인 고속 측정장치를 통한 전자소자의 과도방사선시험에서 다양한 피해현상을 측정할 수 있었고, 열상카메라 촬영을 통하여 과열상태를 관측함으로써 피해현상의 검증과 더불어 소진현상으로의 전개 가능성을 확인하였다.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2017.05a
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• pp.213-217
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• 2017

Since more than 30% of the liquid rocket engine failures occur during the start-up process, and the Space Shuttle Main Engine (SSME) is especially sensitive to small changes in propellant conditions, a 2% error in the valve position or a 0.1sec timing error could lead to significant damage of the engine, simulation modeling of start-up process is important. However, there are many difficulties associated with engine start-up process caused by nonlinear mass flow and heat transfer characteristics associated with filling an unconditioned engine system with cryogenic propellants. In this paper, we modelled a SSME simulation model using partially Computational Fluid Dynamics (CFD) method to solve these problems and checked the performance by comparing with the performance of the simulation model using the lumped method under the state of normal condition.

• Nuclear Engineering and Technology
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• v.19 no.3
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• pp.186-191
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• 1987

In this paper, we suggest the simple and practical direct simulation method for the system reliability calculation In the aspect of system unavailability calculation, this method can simplify the calculation process by applying the hard-wired system fault tree. For the calculation purpose, we use the ESCAF which is developed by Mr. Laviron in France. As a consequence, we estimate the unavailability of OP$\Delta$T & OT$\Delta$T channel in W PWR plants as a value of 8.17576$\times$10$^{-9}$ from IEEE std. 500-1977's reference data. In our calculation, the processing time is no more than 25 sec.

• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.4
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• pp.936-941
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• 2006

To prevent human body injury from oxidative stress, antioxidants are very important and many research about antioxidants are generally being conducted. Hydrogen peroxide$(H_20_2)$ that is one of vitality oxygen species has been seen that cause various diseases, DNA damage and gene change. We have already known that the inhibition effect of Zizania latifolia Radix, Rhizoma on apoptosis induced by $H_2O_2$ in Neuro2A cell. And the purpose of this study was that we made a comparative study on the inhibition effect of apoptosis in Neuro2A cell on the region of Zizania latifolia(Radix, Rhizoma, Herba). Neuro2A cells were cultivated in RPMI(GibcoBRL) with 5% FBS and treated with $H_2O_2$ and Zizania latifolia(Radix, Rhizoma, Herba). Separately we measured the cell viability and analyzed DNA fragmentation. Activity of PARP, Cytochrome C, caspase-9, caspase-3, p53, p21, Bax and Bcl-2 in the cell was examined by using western blot. The results obtained were as Follows: The cell viability in all of Zizania latifolia (Radix, Rhizoma, Herba) treatment (60ug/m1<) decreased significantly compared with that of none treatment(p<0.001). Zizania latifolia Radix increased cell viability was most effective of three regions. But we had no significant difference among three regions. All of Zizania latifolia (Radix, Rhizoma, Herba) increased cell viability about twice as much as that being injury by $H_2O_2$,(Zizania Latifolia (Radix, nhizoma, Herba) 20ug/m1, $H_2O_2$ 200uM, p<0.001). DNA fragmentation developed by $H_2O_2$, but was not developed in all of Zizania latifolia (Radix, Rhizoma, Herba) treatment. PARP, Cytochrome C, caspase-9 and caspase-3 activated all by $H_2O_2$ but were not activated in all of Zizania latifolia (Radix, Rhizoma, Herba) treatment. P53, P2l and Bax activated by $H_2O_2$, and Bcl-2 got into inactivation. But the opposite results appeared in all of Zizania latifolia (Radix, Rhizoma, Herba) treatment. In conclusion, these results suggest that all of Zizania latifolia (Radix, Rhizoma, Herba) inhibit the development of DNA fragmentation and apoptosis by $H_2O_2$and the antioridant action of all of Zizania latifolia (Radix, Rhizoma, Herba) is effective.

• Current Industrial and Technological Trends in Aerospace
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• v.7 no.2
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• pp.121-130
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• 2009

In this paper, the attitude and orbit control subsystem technology of new GEO communication and observation satellite using Sun sensors are introduced and analyzed. COMS is new GEO communication and Earth observation satellite based on EUROSTAR 3000 space bus technology. The attitude and orbit control subsystem of COMS adopts a configuration using three BASS and three LIASS Sun sensors to acquire the attitude error information in the specific reference frames. These Sun sensors are used to acquire Sun direction and to control the spacecraft to keep the relative attitude with respect to a reference Sun direction in both transfer and operational orbits. In this paper, the mathematical models of BASS and LIASS are described as well as their operational implementation in the flight software.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1993.04a
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• pp.177-177
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• 1993

뇌모세혈관내피세포로 구성된 혈액-뇌관문(BBB)은 tight junction으로 구성되어 있을뿐만 아니라 fenestra가 없는 등 BBB가 가진 특성으로 인해 물질 수송에 장벽역할을 하기 때문에 주로 중추신경계 질환시의 약물요법에 많은 제한이 따른다. 따라서 뇌로의 효율적인 약물 송달방법에 대해 많은 연구가 진행중에 있는데 본 연구에서는 BBB의 hyperosmotic opening법을 이용하여 뇌로 잘 수송되지 않는 약물의 뇌송달 방법에 대해 연구하고자 하였다. 먼저 수용성으로 인해 BBB 에 잘 통과하지 않는 물질로 신장 및 뇌영상 촬영시 사용되는 방사성 의약품이 Tc-DTPA를 이용하여, hyperosmotic opening법에 의한 뇌투과 증가정도를 검토하였으며, 실험방법이 확립됨에 따라 뇌암의 항암요법을 위해 뇌로의 투과가 적은 항암제(5-Fluorouracil, 5-FU)의 뇌송달에 대해 본 방법을 적용하여 검토하였다. 실험동물로는 S.D.계 웅성 랫트를 사용하였으며, 실험방법은 다음과 같이 하였다. 랫트의 좌측 외경동맥(left external carotid artery)에 혈류의 역방향으로 혈관 분지점에서 1-2mm 전까지 PE-50 catheter를 삽입하고, 1.6 molal L－(＋)－ arabinose 고장액(1580mOsm)을 0.12ml/sec의 일정한 속도로 30초간 infusion함으로 BBB를 opening 한 다음, 5분 후에 Tc-DTPA를 대퇴 정맥으로 주사하여 0, 10, 30초, 1, 1.5, 2, 3, 4, 5, 7 및 10분 간격으로 대퇴동맥에 설치한 카테타로부터 혈액을 채취하고 마지막 혈액을 취한 후 즉시 단두하여 뇌를 적출하였다. 채취한 뇌를 액체질소에 담근 후 tissue Tek으로 고정하고 autoradiography를 하기 위한 slice와 농도측정을 위해 필요한 부위를 취한 후 감마카운터로 Tc-DTPA의 brain각 부위별 및 혈장농도를 측정하였다. 뇌조직중 혈액부피의 측정은 Tc-albumin를 이용하여 구하였다. 같은 방법으로 5-FU에 대한 실험도 행하였고, 이때 각 혈장 및 조직중의 5-FU함량은 HPLC로 하였다.

• Korean Journal of Comparative Education
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• v.24 no.5
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• pp.1-25
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• 2014

This study intended to examine the English-Medium Instruction (EMI) policy in terms of developmental background and current situation in Chinese and Korean higher education institutions and to provide policy implications for each country. EMI policy in China and Korea shared common characteristics that the EMI courses in both countries were expanded through government leadership at the beginning in order to respond to internationalization since early 2000s. In terms of the differences, EMI policy in China aimed to improve educational quality and nurture bilingual talents while in Korea it primarily aimed to attract international students and internationalize universities. Although both governments took the lead in implementing the policy, universities in two nations responded differently. While the Chinese universities merely followed the government policy to expand EMI courses, its Korean counterparts had a more strong intention to increase EMI courses. Related policy implications were addressed.

• Journal of the Korean Institute of Traditional Landscape Architecture
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• v.30 no.2
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• pp.142-154
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• 2012

This study aimed at learning the characteristics of place identity of the Buan county hall garden and Sangsosan(上蘇山) by looking over the pattern and content of letter-engraved rocks and nearby facilities and history. Especially, we focused on the meaning and contents of the letters in Sangsosan and a Government Office of Buan engraved on rocks in order to learn what the place means. The results of our study are as follows. Buan-hyun(扶安縣) in the Joseon dynasty period blossomed literary culture of enjoying poetry and melody, and this was faithful realization of the concept of "Rakto(樂土)" of 'Saengubuan(生居扶安).' The grand scale letters written by Si-SooPark(朴蓍壽: 1767~1876), head of the office in the early 19th century, in the cursive style on the basis stone of the garden of Buan county building, which was the site of the office of Buan-hyun in the Joseon dynasty period, such as 'Bongraedongcheon(蓬萊洞天)', 'Jurim(珠林)', and 'Okcheon(玉泉)' mean that "'Bongrae', the another name of Buan', is a place where Taoist hermits would live because the spring water of Seorim flows down to be Okcheon.", showing his pride of living Buan. The regions like Seorimjeong, Geumdae(琴臺), and Hyecheon(惠泉) where letters engraved on rocks are located intensively are closely related with those who communicated with Mae-ChangLee(李梅窓: 1573~1610), the slave of the government, and are local attractions and garden traces where the literary culture and scholar's spirit of Buan are well-harmonized. Most of the letters were written from the 19th century to the early 20th century, showing that 4 for landscapes, 8 for Kyungseck(景色: imaginary scenry), 5 for figures, 15 for poems and 2 for others. The ratio of poems is much higher than that of poems in other regions' letters on rocks, and the keyword of the letters is Haecheon. A piece of the place identity heavily influenced by the Taois thermit ideology is revealed by the expressions of 'Bongraedongcheon', 'Sosansaho(蘇山四皓)' or 'the spring water of Haecheon' that was considered as an elixir of Taoist hermits. Seorim the forest, which had been managed after Yeon-Myeong Cho(趙然明: 1797~?), head of the office, planted trees in the 11th year of the reign of King Heonjong(1845), Seorimjeong in the forest, and rocks with engraved letters on them are proof of literary culture and the garden traces showing the characteristics and aspect of Imcheon(林泉) Garden of the office heavily influenced by the Taoist hermit ideology. Along with Naebyeon-san national park and Kyeokpo region, the center of Buan tourism, we hope that cultural heritages including rocks with engraved letters over Seorim park would become a representative cultural heritage and attraction of Buan.