• YAKHAK HOEJI
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• v.52 no.4
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• pp.274-278
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• 2008

Two known lavandulylated flavanones, leachianone A (1) and sophoroaflavanone G (2), were isolated from the roots of S. flavascens Ait. The structures of these compounds were determined on the basis of IR, 1D and 2D NMR in addition to direct comparison with authentic compounds. However, leachianone A (1) and sophoroflavanone G (2) did not have growth inhibition activity against any microorganisms (MIC, >200 ${\mu}g/ml$).

• Journal of Physiology & Pathology in Korean Medicine
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• v.23 no.5
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• pp.1049-1054
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• 2009

The effect of Sacchromyces cerevisiae-Fermented Sophorae Radix water extract (SFS) on production of hydrogen peroxide and nitric oxide (NO) from mouse macrophage Raw 264.7 Cells treated with nicotine (1 mM) was investigated through this study. SFS (0, 25, 50, 100, 200, 400 ug/mL) was simultaneously treated with nicotine (1 mM) during culture of 4, 20, 24, 44, 48, 68, and 72 hr. And the intracellular productions of hydrogen peroxide were measured by dihydrorhodamine 123 (DHR) assay. NO production after 24 hr treatement was measured with Griess reagent assay. SFS restored the production of hydrogen peroxide and NO reduced by nicotine (1 mM) in Raw 264.7 Cells. These results suggests that SFS could be supposed to have the immunological activity concerned with macrophage's oxidative burst including hydrogen peroxide and NO.

• Journal of Society of Preventive Korean Medicine
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• v.9 no.1
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• pp.135-141
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• 2005

Bioassay-directed fractionation of the dired roots of Sophorae Radix led to the isolation of Sophoraflavanone G. Their structures were elucidated using 1H-NMR, 13C-NMR, UV, IR and mass spectral ananlyses. These compounds exhibited a moderate antimicrobial activities against Streptococcus gordonii, Actinobacillus actinomycetemoomitans and Porphylomonas gingivalis.

• Proceedings of the Korea Water Resources Association Conference
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• 2007.05a
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• pp.790-794
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• 2007

본 연구에서는 경기도 안성시 쌍지리에 위치한 고삼저수지 상류의 소유역을 대상으로 홍수재해 전후의 토지이용별 유출량과 오염농도를 실측하여 분석하였으며, 강우 형태에 따른 오염물질의 배출특성을 알아보기 위해 유역관리모형인 BASINS/WinHSPF 모형을 적용하였다. 오염물질의 배출은 오염원의 형태뿐만 아니라 개별 오염원의 발생형태에 따라 수역으로 유입되는 물질량이 달라지며, 특히 강우의 영향에 의한 시기별 배출량의 변화가 크다. 이렇게 적용된 모형에 대상지구의 강우량, 강우강도, 강우지속시간 등의 확률강우를 적용하여 강우에 따른 홍수재해 전후의 오염물질 배출 특성을 파악하고 이에 따른 오염 물질 저감 방안에 대해 연구하였다.

• Proceedings of the Korean Information Science Society Conference
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• 2002.10d
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• pp.328-330
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• 2002

본 논문에서는 역전파 신경망(Backpropagation Neural Network)을 시계열 데이터인 주가 데이터를 이용한 주가 예측의 정확도를 향상시키기 위한 학습 방법으로 적용하였다. 실제 증권거래소의 종목 데이터에서 비교적 등락폭이 안정적인 각 산업분야별 5개 기업의 5일 이동평균선 데이터 240개를 훈련 데이터로, 20개는 테스트 데이터로 이용하였다. 선정된 입력 데이터를 은닉층의 개수와 은닉 노드의 개수 등을 달리 하면서 10,000번의 훈련을 통해서 실험 하였으며, 그 결과 1개의 은닉층을 사용한 네트워크1은 20개의 테스트 데이터 사이의 19개의 신호 중 14개를 예측하였고, 2개의 은닉층을 사용한 네트워크 2는 16개를 예측하였다. 시험 결과를 통해서 보듯이 은닉층을 2개 사용하였을 때 보다 좋은 실험 결과를 얻을 수 있었으며, 역전파 신경망 모델이 주가 예측에 적합하다는 것이 증명되었다.

• The Journal of Korean Medicine
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• v.21 no.2
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• pp.37-42
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• 2000

Objectives and Methods : Unlike respiratory anaphylaxis responses, mediators responsible for cardiovascular responses are not clearly elucidated. Main characteristics of cardiovascular anaphylaxis include hypotension and cardiac failure (anhythmia and cardiac contraction failure). In this experiment, the fractionations of Sophorae Radix (SR) were tested for its preventive effects against cardiovascular anaphylaxis in pithed rats. Results : Of the SR fractionations, water fractions, at the concentration of 20 and 60mg/kg, was significantly effective on all the cardiovascular changes in pithed rats. Also, of the cardiovascular changes, depressor response was significantly attenuated by the ethyl acetate (EA) fraction, at the concentration of 60mg/kg. Conclusions : These results suggest that water and EA fractions of the SR fractionations possess anti. anaphylactic effects in pithed rats. Additional research is needed to identify active principles for the observed pharmacological effects.

• Magazine of the Korean Society of Agricultural Engineers
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• v.40 no.1
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• pp.43-48
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• 1998

In order to provide basic information for the estimation of evapotranspiration for grass (Joycia Japonica), both field lysimeter experiment and model prediction were performed to estimate daily ET Various methods were used to predict daily reference crop ET and crop coefficients. Measured mean daily ET during the 1997 growing season was 4.5mm Model predicted mean daily ET during the 1997 growing season varied from 3.6 to 4.7mm depending on the prediction model Crop coefficients varied from 0.96 to 1.27 depending on the prediction model Comparison of the seven reference crop ET prediction methods used in this study shows that the Penman-Monteith method gave the smallest ET while the Hargreaves method gave the largest ET. The crop coefficient by the corrected Penman method was 1.03, which is closest to 1.0, suggesting that this method may he the best prediction method.

• Journal of Haehwa Medicine
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• v.5 no.2
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• pp.503-507
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• 1997

The cytotoxicity-guided fractionation of the roots of Sophora flavescens (Leguminosae) extracts led to the isolation of fifteen active principles 1~15, responsible for the cytotoxicity against five kinds of cultured human tumor cell lines, i.e., A549(non small cell lung), SK-OV-3(ovary), SK-MEL-2(skin), XF498(central nerve system) and HCT-15(colon), evaluated by SRB method in vitro. Compounds 2~14 were classified as unusual flavonoid occurred exclusively in this species and the proliferation of each examined tumor cells were significantly inhibited during the continuous exposure to compounds 1~15 for 48 hours, respectively.

• Korean Journal of Pharmacognosy
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• v.31 no.4
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• pp.421-425
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• 2000

HPLC method was applied to the quantitative analysis of lupine alkaloid, matrine from alkaloid fraction of Sophorae Radix (Sophora flavescens). The average content of matrine from 20 Sophorae Radices showed $0.13{\pm}0.06%$.

• The Korean Journal of Pesticide Science
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• v.17 no.4
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• pp.402-410
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• 2013

Insect pests damages are increasing on the field of Lycium chinense under environment- friendly management Thus, we was to monitor the occurrence of pests on organic L. chinense in Chungnam Cheongyang and, insecticidal effect of eco-friendly agricultural materials (EFAMs) were tested against major pests. When the buds come out, injury by L. chinense was very high causing the high population density of Myzus persicae in late May and early June, and the injury by Lema decempunctata was increased from mid-June. Otherwise, injuries by Eriophys macrodonis, Henosepilachna vigintioctomaculata and Hedma spp. were continued throughout the growing season. From the fruit held in late July, Hemipteran insects including Plautia stali and Halyomorpba balys were sucking the fruit, and their injury to L. chinense were gradually increased. For the eco-friendly environmental control of M. persicae, L. decempunctata and E. macrodonis, EFAMs containing Sophora flavescens, Melia azedarach (Chinaberry), Chenopodium ambrosioides (Mexican tea), Quassia amara (Amargo), Stemona sessilifolia, Sophora seeds and Nepeta cataria (Catmint), were selected and used to control the insect pests. Control effects of the mixed extract with S. flavescens and Sophora seeds against M. persicae and L. decempunctata were higher than any other EFAM as 84.0% and 86.6%, respectively. In case of E. macrodonis, its control effect was good with the mixed extract with S. flavescens, C. ambrosioides and M. azedarach.