• Journal of the Korean Crystal Growth and Crystal Technology
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• v.8 no.1
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• pp.169-178
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• 1998

The crystal phases precipitated in various compositions glass of CaO-$SiO_2-P_2O_5$ system, were identified by XRD. E composition (CaO 49.4, $SiO_2\;36.8,\;P_2O_5$ 8.8 wt%) glass in which both apatite(($Ca_{10}(PO_4)_6O$ and $\beta$-wollastonite($CaSiO_3$) crystals would precipitate by heating, was selected as an experimental composition to prepare the glass ceramics with high bending strength and good bioactivity to the living bone. Glass powders of E composition were unidirectionally crystallized at $1050^{\circ}$C in the temperature-gadient furnace and the resultant glass ceramics were characterized. Bending strength of the glass ceramics was also measured. To investigate the bond forming ability between the glass ceramics and living bone tissue, soaking test of glass ceramics in simulated body fluid was carried out. Densed glass ceramics composed of apatite and $\beta$-wollastonite crystal were prepared by unidirectional crystallization under the optimum conditions. (2 0 2) plane of $\beta$-wollastonite crystals tended to grow perpendicularly to the crystallization direction. Average bending strength of this glass ceramics was 186.9 MPa, higher than that of the glass ceramics prepared by isothermal (not directional) crystallization In soaking test, a thin layer of apatite crystallite was formed on surface of the glass ceramics in 3 days. Apatite crystals formed on the glass ceramics could be act a role to make the chemical bond between the glass ceramics and living bone tissue.

• Journal of the Korean Geographical Society
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• v.43 no.2
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• pp.235-252
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• 2008

Many cartographers have for many years searched for a way to construct cartograms in which the sizes of geographic areas such as states, counties or census tracts are reseated in proportion to their population or some other socio-economic properties. While many techniques and algorithms for creating cartograms have been proposed, some of them are still extremely complex to generate in a proper manner, and many of them suffer either from this lack of readability or from seamless integration with GIS software. This paper, therefore, presents a simple population cartogam technique based on the Circular Cartogram Algorithm(CCA) by Dorling(1996) to tackle these drawbacks by drawing the areas as simple circles for use as a base map and linking the construction with GIS mapping processes. For an automated approach in the cartogram generation, this paper proposes a close coupling method of ArcView GIS 3.3. package in order for users to access to the cartopam algorithm. Then, they will be available through an interface that the ArcView GIS system allows user-written routines to be accessed easily. The CCA and its coupling architecture ensure to improve the potential applicability of the use of cartograms to census mapping at practical levels. As the cartogram examples, cartograms of population and property types in 2005 Korea census data sets are illustrated in the end, by which viewers can easily identify the residential concentration and their relative ratio in Seoul metropolitan area.

• Journal of the Economic Geographical Society of Korea
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• v.19 no.1
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• pp.51-67
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• 2016

Urban development-related growth in recent years has become a qualitative growth based on regional identity, rather than a hardware-based growth. For this purpose, strategic approaches to the value of cultural assets of the city are required for competitiveness of the city. In this paper, I seek a model for urban regeneration and regional development through empirical case studies of cultural assets and utilize the 'Seoul Fairy Tale Festival' in terms of strengthening regional competitiveness. By analyzing detailed elements of the 'Seoul Fairy Tale Festival' case, the hardware infrastructure, software and governance structures, diverse contentsware, ecosystem characteristics centered on the humanware, and circular structure was studied. As a feature of cultural assets, combined with the management of physical assets and operations of several programs, was the basis for creating a synergy effect of creating an identity for the region. In addition, it was confirmed the possibility of a regional-rehabilitation type of urban regeneration that is based on the expansion of existing facilities, and a regional-innovation type of urban regeneration that is based on a fusion of characteristics. This analysis is significant in terms of the possibility of large urban regeneration based on cultural assets associated with the festival, as well as physical assets and by combining various governance stakeholders for the festival, it can be concluded that it provided an indigenous virtuous cycle.

• Journal of Animal Science and Technology
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• v.46 no.3
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• pp.495-502
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• 2004

Intimin, the product of eae gene in EHEC O157:H7, is required for intimate adherence. In this study, the C-terminaI region(281 amino acids) of the EHEC OI57:H7 intimin were expressed as a protein fusion with (His)$_6$ which was used to raise antiserum in rabbits. The antiserum reacted in western blot with a 94kDa outer membrane protein of EHEC O157:H7. It was observed that the antibody titers both in egg yolk and serum appeared in 2${\sim}$4 weeks after immunization with fusion protein. At the time of 8 weeks, the titre of egg yolk was found to be higher than that of sera. According to the results of neutralization test, chicken egg-yolk antibody(lgY) against the recombinant intimin strongly reacted to EHEC O157:H7. We conclude that a truncated recombinant intimin could be used as an immunogen to elicit antibody(lgY) against O157:H7.

• Korean Journal of Food Science and Technology
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• v.25 no.2
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• pp.148-153
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• 1993

Composition and structure of synthetic glucitol fatty acid polyesters (GPE)-a potential fat substitute-were investigated. Also degree of substitution (D.S) of GPE was determined according to the relative ester distribution within it to evaluate the feasibility of GPE using as a fat substitute. The GPE was separated into single ester group by a normal-phase HPLC and D.S of it was identified to be 6. Absorption band at $1747\;cm^{-1}$ in the IR spectrum of GPE indicated that there were ester bonds within GPE molecules. which link fatty acid moiety to glucitol. Disappearance of the hydroxyl proton signals of glucitol in the H-NMR spectrum of GPE implied that most of hydroxyl groups in glucitol participated in the formation of ester bonds with fatty acids. In addition the D.S estimated from the quantitative proton integration of GPE coincided well with the D.S of GPE determined by hydroxyl value measurement. In conclusion, the GPE synthesized in this study was found to be a glucitol fatty acid hexaester so that it is expected to be used as a fat substitute in the near future.

• Journal of the Korean Society of Food Science and Nutrition
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• v.32 no.5
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• pp.745-751
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• 2003

This study was carried out to investigate whether peptide produced from wheat protein by enzyme hydrolysis can be used as a natural antimicrobial agent. Antimicrobial peptide was obtained from wheat protein hydrolyzed by 7 of pretense. The produced antimicrobial peptide was purified through ultrafiltration, membrane filtration and HPLC and molecular weight and amino acid sequence of the purified antimicrobial peptide were determined. Among hydrolysate produced from wheat protein by 7 of protease, antimicrobial activity was observed for the peptide obtained from Asp. saito protease. The Asp. saito protease did produce antimicrobial hydrolysate showing the highest antimicrobial activity at reaction condition of 37$^{\circ}C$ and pH 6.0, but not at reaction condition above 5$0^{\circ}C$. Wheat protein hydrolysate was fractionated by membrane filtration and showed antimicrobial activity between molecular weight 1,000~3,000. The antimicrobial activity fraction obtained by membrane filtration was separated through HPLC and showed antimicrobial activity in the peak of retention time 31.1~31.8 min. We could convince this hydrolysate as heat-stable peptide since antimicrobial activity was maintained after treated with heat for 15 min at 121$^{\circ}C$. Molecular weight of antimicrobial peptide identified by MALDI-mass was 1,633. Amino acid sequence of antimicrobial peptide was cysteine, glycine, prolin, prolin, prolin, valine, valine, alanine, alanine and arginine.

• Journal of the Korean Institute of Landscape Architecture
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• v.48 no.5
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• pp.89-106
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• 2020

This study examines the functionality and landscape design specifics of the outdoor space of representative commercial multi-complexes in Korea in order to overview the design trends of outdoor landscaping trends. Through surveying the composition of outdoor spaces along with their relation to the surrounding landscape, open spaces, and the neighboring communities, this paper identified the change in trends regarding the characteristics of outdoor landscape planning and acknowledged the enhanced public value of outdoor space. This study asserts that the characteristics of outdoor spaces can best be understood by examining the ways in which the outdoor space relates to adjoining commercial multi-complexes and the surrounding landscape. Focusing on the relationships that outdoor space establishes, commercial multi-complexes can be categorized as follows: in/outdoor separated type, in/outdoor semi-open type, surrounding landscape-projected type, and surrounding landscape-combined type. By studying the landscape design specifics of the outdoor space of representative cases of each type, the following has been concluded: First, the amount of outdoor space has expanded in terms of importance and function while serving to assist in various activities and participatory experiences, and no longer merely serves as a backdrop of commercial facilities. Second, with the strengthened connectivity between in/outdoor spaces, the elements of outdoor surroundings are more actively introduced indoors to improve amenities. Through directly connecting certain indoor program spaces with outdoor spaces, commercial multi-complexes tend to provide richer combined experiences. Third, with the expansion of outdoor space functionality, commercial multi-complexes are increasingly recognized as a quasi-public space, making good example of liminal space. In light of the recent case of development plans linked with public open spaces in suburban settings, commercial landscape design shows the possibility of creating an open space that can function as a center for local culture and green networks in the community.

• Korean Journal of Environmental Biology
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• v.24 no.2 s.62
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• pp.166-171
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• 2006

To elucidate the effect of phytoestrogens on the prevention of neurodegenerative disease in postmenopausal women, the expression of occludin which build up the blood-brain barrier was examined in hippocampus following oral administration of estrogen (E2), genistein, diadzein or combination of genistein and diadzein in ovariectomized (OVX) female rats. E2 significantly increased occludin mRNA level in OVX rat hippocampus, suggesting that estrogen is a physiological regulator for structural integrity of the blood-brain barrier in hippocampus. Following isoflavone diet for 4 weeks, there was significant increase in occludin mRNA level in hippocampus, suggesting that isoflavone diet may be effective for protection of structural integrity of blood-brain barrier in hippocampus from degenerative changes in estrogen deficiency.

• Journal of Energy Engineering
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• v.20 no.3
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• pp.171-177
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• 2011

PVA/GLA/$Al_2O_3{\cdot}3SiO_2$ composite membranes were prepared through the reaction polyvinyl alcohol (PVA) with glutaraldehyde (GLA) as a cross-linking agent and subsequently adding aluminum silicate ($Al_2O_3{\cdot}3SiO_2$) as an inorganic material. The water uptake decreased as the GDL contents increased due to cross-linking process of PVA with GDL, and the ion conductivity increased as the $Al_2O_3{\cdot}3SiO_2$ contents increased in PVA/GLA/$Al_2O_3{\cdot}3SiO_2$ composite membranes. The cross-linking structure of the polymers was confirmed using IR and the tendency of water uptake. The thermal analysis of the copolymers was carried out by TGA. TGA results showed that PVA/GLA composite membrane were more heat-resistant than PVA due to the cross-linking of PVA, and the heat stability of the composite membranes improved much more as the concentration of $Al_2O_3{\cdot}3SiO_2$ increased. Membranes prepared in this study seem to be have thermal stability and increase a tendency of the cation conductivity up to $60^{\circ}C$, but to be exhibit lower performance tendency at over $90^{\circ}C$. Therefore, it is necessary to do more aggressive effort to explore the possibility of application as an ion-conductive composite electrolyte.

• Science of Emotion and Sensibility
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• v.14 no.4
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• pp.531-536
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• 2011

The precise measurement of human emotion is of pivotal importance in the field of emotion science. Based on the perspective of psychoneuroimmunoendocrinology, human emotion is now considered to be measurable by body fluid. The biological molecule cortisol, which is known for the stress hormone, has been widely investigated to help researchers to estimate the stress loaded on human body. Until now, several measurement techniques such as High Performance Liquid Chromatography (HPLC), fluorometric assay, and reverse phase chromatography have been developed. However, since these measurements are expensive, take relatively long time for an operation, and they are not portable, they are not appropriate for POCT (point of care testing). In this paper we demonstrate the performance of a miniaturized-microwave resonant device in the measurement of cortisol. Our method has many advantages in that it requires a small volume of sample, has fast response time, is easy to operate and needs no labeling process. Besides, it will shed a light on the measurement techniques for emotion science.