• Title/Summary/Keyword: 결합 가능성

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The Effects of Panax Ginseng Extract on Antioxidative Enzyme Activity in Ovariectomized Rats (인삼 추출물이 난소를 절제한 백서의 항산화효소 활성에 미치는 영향)

  • 하배진;황일영
    • Journal of Life Science
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    • v.12 no.3
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    • pp.349-356
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    • 2002
  • In order to observe the bioactivity of ovariectomized rats, nonovariertoized (sham) group, ovariectomized (Ovx) group, ovariectomized ginseng total saponin (GTS)-treated (Ovx+ GTS) group and ovariectomized ginseng water extract (GW)-treated (Ovx+CW) group were made. We measured AST (L-aspartate aminotransferase) and ALT (L-alanin aminotransferase) in sera, and MDA (malondialdehyde:lipid peroxidation), SOD (superoxide dismutase), catalase, total-glutathione (GSH + GSSG) and GPx (glutathione peroxidase) in liver tissue total homogenates of rat. AST activity of serum in Ovx group was 2.11 times increased, but ALT activity was not changed compared to Sham group. In AST activity, they tend to decrease significantly in each substance such as GTS and GW administered group. Lipidperoxides of each fraction in Ovx group were highly increased compared to Sham group. Extracts of ginseng-treated group markedly inhibited lipid peroxidation by 62% ∼72%. And as the result of the measurements of SOD, catalase, total-glutathione and GPx which are antioxidant enzyme, antioxidant enzymes in Ovx group much lower than in Sham group. But they were significantly increased in each substance such as GTS and GW, administered group. Based on the results, it is supposed that more produced free radicals decreased antioxidant enzyme. And it is also thought that extracts of ginseng can inhibit aging by reducing antioxidant enzyme.

Inhibitory Effect of Organic Acids and Natural Occurring Antimicrobials Against Staphylococcus aureus Isolates from Various Origins (다양한 유래에서 분리된 황색포도상구균에 대한 유기산과 천연항균물질의 저해 효과)

  • Kim, Bo-Ram;Yoo, Jin-Hee;Jung, Kyu-Seok;Heu, Sung Gi;Lee, Sun-Young
    • Journal of Food Hygiene and Safety
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    • v.27 no.4
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    • pp.449-455
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    • 2012
  • The purpose of this study is to evaluate antimicrobial effects of organic acid and some natural occurring antimicrobials against Staphylococcus aureus isolated from various origins (vegetables, peanut, pea leaf, kim-bab, person, perilla leaf, and animal) and to calculate their MIC and MBC values. Five organic acids (acetic, lactic, citric, malic, and propionic acid), three essential oils (carvacrol, thymol, and eugenol), and two other natural antimicrobials (nisin and cinnamic acid) were evaluated for their antimicrobial effects against 113 strains of S. aureus using combination treatments. Propionic acid (7%), nisin (1%), thymol (1%), carvacrol (1%) showed antimicrobial activities against S. aureus strains in agar disc diffusion test. And, carvacrol, thymol, and nisin were found to be the most effective with the lowest MIC values of 0.0313%, 0.0625%, and 0.0625% against S.aureus, respectively. Propionic acid (0.2313%) and citric acid (0.6000%) were the most effective among organic acids tested. Therefore, these five antimicrobials were selected for next combination treatments. Combination of propionic acid and citric acid were showed the strongest inhibitory effectiveness against S. aureus among combination treatments. These results suggest that organic acid such as propionic and citric acid, and natural occurring antimicrobial such as nisin, carvacrol, and thymol might be possibly used as preservatives for inhibiting S. aureus in foods.

Double Salt Precipitation Behavior of Rare Earth by Sodium Sulfate in Sulfuric Liquor of Waste Permanent Magnet Scrap (폐 영구자석 스크랩 황산침출용액으로부터 황산나트륨에 의한 희토류 원소 복염침전 거동 고찰)

  • Yoon, Ho-Sung;Kim, Chul-Joo;Chung, Kyeong Woo;Kim, Ji-Hye;Lee, Eun-Ji;Yoo, Seung-Joon
    • Resources Recycling
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    • v.26 no.5
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    • pp.39-47
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    • 2017
  • In this study, the precipitation of rare earth-sodium sulfate with sodium sulfate was conducted in order to separate rare earth from Fe in rare earth sulfate solution. Neodymium (Nd) was easily precipitated as Nd-sulfate salt with sodium sulfate, on the other hand, excessive sodium sulfate was needed for the precipitation of Dy-sulfate salt. Also neodymium not only promoted the precipitation of dysprosium sulfate salt but also increased recovery of dysprosium sulfate salt in sulfuric acid solution. At the condition of $60^{\circ}C$ precipitation temperature, 3 h reaction time, 7 equivalents sodium sulfate, the recovery of neodymium and dysprosium sulfate salt was 99.7% and 94.3% respectively from the sulfuric acid solution containing Nd of 23.39 mg/ml and Dy of 8.67 mg/ml. Lastly, from the results of separation of Dy to Nd by the method of sulfate double salt, the effect of salting out with NaCl is important to increase the grade of Dy, and 98.7% of Dy grade could be obtained in this study.

A Pychoeducational Group Intervention for Women with Primary Breast Carcinoma (유방암 환자에 대한 심리교육 집단개입의 효과)

  • Hwang, Sook-Yeon;Lee, In-Soo;Park, Byeong-Woo
    • Korean Journal of Social Welfare
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    • v.51
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    • pp.93-118
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    • 2002
  • The objective of this study was to determine the effect of a psycho-educational group intervention in reducing psychologic distress and enhancing coping in Korean breast cancer patients. The patient selection criteria were age younger than 70 years, having any postoperative adjuvant therapy, and surgery undergone within the previous 12 months as of the start of the study and there were 70 patients eligible for this criteria. They were randomized into three groups; experimental group(24 patients), wait-list control group(24 patients) and wait-list group(36 patients). We conducted a 8-week, structured, psychosocial group intervention, which used psycho-educational strategies combining education and psychological support. Subjects were assessed for psychological distress and coping by administering the Beck Depression Inventory(BDI) and the Ways of Coping Checklist-Revised(WCCL-R) at the baseline and after 8 weeks. Forty eight patients were participated and thirty five patients completed the study. The experimental group had significantly lower scores than the controls for depression on the BDI(p=.012) after 8-week intervention. However, coping did not show a significant difference on WCCL-R after the intervention. Despite of some limitations, the results of this study suggest that a short term psychosocial group intervention produces a significant improvement in the quality of life of patients with primary breast carcinoma in Korea in terms of managing depression.

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Liberalism and Perfectionism (자유주의와 완전주의)

  • Kim, Young-kee
    • Journal of Korean Philosophical Society
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    • v.144
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    • pp.83-111
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    • 2017
  • The purport of this essay is to examine the possible compatibility of liberalism and perfectionism. Liberalism is typically considered as anti-perfectionism. So communitarian critique of liberalism focused on the effects of its anti-perfectionism. But liberalism could be interpreted as compatible with perfectionism. Joseph Raz attempts to develop and defend "perfectionist" liberalism. He rejects anti-perfectionist "neutrality" and claims that the goal of political action is to encourage pursuit of what is truly good and discourage pursuit of what is morally unworthy. Despite this strong perfectionist claim, Raz's political philosophy gives pride of place to individual liberty, or autonomy, which he considers to be intrinsically valuable. One exercises autonomy in choosing among a plurality of human goods. Nonetheless, Raz forthrightly denies the value of autonomy used to choose what is morally bad and says that society has no reason to protect worthless, much less morally evil, options. Raz is more conventionally liberal, however, in espousing a version of J. S. Mill's "harm principle", arguing that a due regard for autonomy rules out government use of coercive means to discourage "victimless" immoralities. However, there are some serious questions about whether Raz's strong perfectionism can support his principled rejection of "morals legislation". I think that if his strong perfectionism could be a little "weakened" and his autonomy could be interpreted as having only formal value rather than having intrinsic value, then his perfectionism could be compatible with liberalism.

Whitehead's Concept of Proposition and Creative Advance of Nature (화이트헤드의 명제론 연구 - 화이트헤드의 명제론과 현실의 창조적 전진 -)

  • Chun, Chul
    • Journal of Korean Philosophical Society
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    • v.116
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    • pp.351-370
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    • 2010
  • Whitehead's metaphysics and philosophy of nature rest on his awareness of the metaphysical problem of the relation between "I", the "creative advance" and forces of the universe. Whitehead attempted to systematize human experience of the world based on logical explorations. In this context it is important to note that his discussion of proposition and language is closely connected with his works on a systematic theory of nature. Whitehead proposes a metaphysical concept of proposition also based on the creative advance of the universe. His theory of proposition is designed to show that human language is constructions of the relations between logical and real events in the creative universe which refer to a particular point of view. In this view, a variety of verbal possibilities in the multiple worlds can be realized in the same proposition. For Whitehead the emergence of novelty in the function of proposition is an essential property of the creative universe. This paper will try to give a discussion to Whitehead's theory of proposition with regard to the emergence of nature. Especially I emphasize in this paper Whitehead's idea and meaning of proposition for the development of the creative advance of nature as one aspect of particular importance.

GEMS BrO Retrieval Sensitivity Test Using a Radiative Transfer Model (복사전달모델을 이용한 GEMS 일산화브로민 산출 민감도 시험)

  • Chong, Heesung;Kim, Jhoon;Jeong, Ukkyo;Park, Sang Seo;Hong, Jaemin;Ahn, Dha Hyun;Cha, Hyeji;Lee, Won-Jin;Lee, Hae-jung
    • Korean Journal of Remote Sensing
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    • v.37 no.6_1
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    • pp.1491-1506
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    • 2021
  • To estimate errors in GEMS retrievals for bromine monoxide (BrO) total vertical column densities(VCDs), we perform a sensitivity test using synthetic spectra generated by a radiative transfer model. Hourly synthetic data are produced for 00-07 UTC on the first day of every month in Jul 2013- Jun 2014. Solution errors estimated by the optimal estimation method tend to decrease with increasing air mass factors (AMFs) but increase when AMFs are larger than 5. Interference errors induced by formaldehyde (HCHO) absorption appear to be larger with smaller BrO AMFs. Total BrO retrieval errors estimated by combining solution and interference errors show an average of 26.74±30.18% for all data samples and 60.39±133.78% for those with solar zenith angles higher than 80°. Due to interfering spectral features and measurement errors not considered in thisstudy, errorsin BrO retrievals from actual GEMS measurements may have different magnitudes from our estimates. However, the variability of errors assessed in this study is still expected to appear in the actual BrO retrievals.

The Characteristics of Diisopropyl Methylphosphonate Adsorption on Zirconium-based Metal Organic Frameworks Manufactured by using Different Acids as Modulators (서로 다른 산을 조절인자로 활용하여 제조한 지르코늄 기반 금속유기골격체의 Diisopropyl Methylphosphonate 흡착 특성)

  • Jang, Wonhyeong;Kim, Honghyun;Jeong, Sangjo
    • Applied Chemistry for Engineering
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    • v.32 no.5
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    • pp.524-531
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    • 2021
  • Depending on the type and amount of acid used as a modulator in the manufacturing process, the structural properties of UiO-66 can be modified and the adsorbability of chemical warfare agents can be enhanced. In this study, several acids as a modulator were used to synthesize UiO-66. Their properties were analyzed with FT-IR, XRD, titrator, and adsorption isotherms using chemical warfare agent simulant, DIMP. The UiO-66, structurally damaged by hydrochloric acid as a modulator, showed lower crystallinity and DIMP adsorption capacity and also smaller specific surface area and volume of voids compared to those of UiO-66, which was manufactured using acetic acid, and formic acid as a modulator. Additionally, UiO-66 which was synthesized by adding formic acid and hydrochloric acid as a modulator, showed the highest DIMP adsorption capacity and is likely to be used as an adsorbent for chemical warfare agent in the future.

Regulation of Cinnamyl Alcohol Dehydrogenase (CAD) Gene Family in Lignin Biosynthesis (리그닌 생합성에서 cinnamyl alcohol dehydrogenase (CAD) 유전자 family의 조절)

  • Kim, Young-Hwa;Huh, Gyung-Hye
    • Journal of Life Science
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    • v.31 no.10
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    • pp.944-953
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    • 2021
  • Lignin is a complex phenylpropanoid polymer abundant in the cell walls of vascular plants. It is mainly presented in conducting and supporting tissues, assisting in water transport and mechanical strength. Lignification is also utilized as a defense mechanism against pathogen infection or wounding to protect plant tissues. The monolignol precursors of lignin are synthesized by cinnamyl alcohol dehydrogenase (CAD). CAD catalyzes cinnamaldehydes to cinnamyl alcohols, such as p-coumaryl, coniferyl, and sinapyl alcohols. CAD exists as a multigenic family in angiosperms, and CAD isoforms with different functions have been identified in different plant species. Multiple isoforms of CAD genes are differentially expressed during development and upon environmental cues. CAD enzymes having different functions have been found so far, showing that one of its isoforms may be involved in developmental lignification, whereas others may affect the composition of defensive lignins and other wall-bound phenolics. Substrate specificity appears differently depending on the CAD isoform, which contributes to revealing the biochemical properties of CAD proteins that regulate lignin synthesis. In this review, details regarding the expression and regulation of the CAD family in lignin biosynthesis are discussed. The isoforms of the CAD multigenic family have complex genetic regulation, and the signaling pathway and stress responses of plant development are closely linked. The synthesis of monolignol by CAD genes is likely to be regulated by development and environmental cues as well.

The Rheology of Cement Paste Using Polycarboxylate-Based Superplasticizer for Normal Strength-High Fluidity Concrete (보통강도 고유동 콘크리트용 PC계 고성능 감수제를 사용한 시멘트 페이스트의 레올로지 특성 평가)

  • Kong, Tae-Woong;Lee, Han-Seung
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.9 no.3
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    • pp.276-286
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    • 2021
  • General high fluidity concrete is the area of high strength concrete with a high amount of cement to secure the required fluidity and workability. Since most of the concrete structures currently used have normal strength, there is a limit to the practical expansion and practicality of use. Thus it is necessary to develop normal strength-high fluidity concrete with low binders that can be used not only in general buildings but also in special buildings, and can greatly reduce construction time and save labor costs. This requires to develop and apply the polycarboxylate-based superplasticizer. In this study, PCE was prepared for each combination of starting materials(WR, HB, RT) and the rheological properties of cement paste were analyzed using ringflow cone and a rotary viscometer. As a result, when PCE with a combination of WR 80%, HB 6.5%, and RT 13.5% was applied, the yield stress can be minimized while securing the plastic viscosity at level of the normal strength. In addition, high fluidity due to the high dispersion effect was confirmed.