• Journal of the Korea Institute of Information and Communication Engineering
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• v.19 no.6
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• pp.1296-1300
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• 2015

Ganglion cysts are commonly observed cystic tumor in association with the joints and tendons of the appendicular skeleton. In this paper we propose a method to extract ganglion cysts from ultrasound images with intelligent image processing. The method consists of fuzzy stretching preprocessing to enhance the contrast between related organs and 8-directional contour tracking to model the boundaries of the cysts and labelling procedure to compute the size of cysts. In experiment, we verified that the proposed method extracts ganglion cysts accurately from ultrasound images.

• Journal of the Speleological Society of Korea
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• v.37 no.38
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• pp.26-38
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• 1994

태백산지의 내륙산간에 해당하는 태백시는 강원도의 주요 지역을 연결하는 결절지의 구실을 할 수 있는 지리적 위치에 있으며, 용연동굴 뿐만 아니라 많은 석회동굴이 산재하고 동굴의 보고 지역이다. 지금까지 이곳 주민의 주산업은 석탄광업에 의존하여 왔으나 현재는 정부의 석탄합리화 정책으로 인한 탄광의 폐광으로 마땅한 수익원이 없으므로 이촌향도 현상이 심화되어 가고 있다. 이러한 피폐를 탈피하기 위해서는 안정성이 높은 생활환경을 만드는 것이 시급한 이곳의 과제라고 하겠다.(중략)

• Proceedings of the Speleological Society Conference
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• 1994.11a
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• pp.88-89
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• 1994

태백산지의 내륙산간에 해당하는 태백시는 강원도의 주요 지역을 연결하는 결절지의 구실을 할 수 있는 지리적 위치에 있으며, 용연동굴 뿐만 아니라 많은 석회동굴이 산재하고 동굴의 보고 지역이다. 지금까지 이곳 주민의 주산업은 석탄광업에 의존하여 왔으나 현재는 정부의 석탄합리화 정책으로 인한 탄광의 폐광으로 마땅한 수익원이 없으므로 이촌향도 현상이 심화되어 가고 있다. 이러한 피폐를 탈피하기 위해서는 안정성이 높은 생활환경을 만드는 것이 시급한 이곳의 과제라고 하겠다.(중략)

• The Journal of the Korea Contents Association
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• v.11 no.9
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• pp.429-436
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• 2011

There have been several studies reporting that vocal misuse and abuse causes voice problems, as well as laryngeal disease such as laryngitis, vocal nodules, vocal polyp. But few researches have investigated amounts or rates of vocal misuse or vocal abuse of patients. Therefore, the author of this study developed measuring device for vocal misuse and abuse behaviors and compared frequency of vocal misuse and abuse behaviors of normal children and children with vocal nodules. The subjects of this study were five normal children and five children with vocal nodules who were male, lower graders of elementary schools(first to third graders). Based on the results of this study, the frequency of the children with vocal nodules in vocal misuse and abuse using was 5,411(${\pm}145$) and that of the normal children was 3,133(${\pm}257$). The frequency of vocal misuse and abuse behaviors of the children with vocal nodules was around 1.5 time significantly higher than that of normal children(p<.001).

• Journal of Yeungnam Medical Science
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• v.25 no.2
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• pp.102-107
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• 2008

Background : Malignant pulmonary nodules account for 30 to 40 percent of all solitary pulmonary nodules (SPNs). Therefore, characterization of SPNs is very important for treatment. Recently, dynamic CT has been widely used for tissue characterization and formation of differential diagnoses. The purpose of this study was to evaluate the ability of dynamic CT to formulate the differential diagnosis of SPNs. Materials and Methods : Nineteen patients with SPNs underwent dynamic CT (unenhanced scans, followed by a series of images at 20, 40, 60, 80, 100, 120, 140, 160, and 180 sec after intravenous injection of contrast medium). Diagnosis of SPN was performed based on pathologic findings in needle biopsy samples. Peak enhancement, net enhancement, slope of enhancement, and maximum relative enhancement ratio of the SPN were measured on dynamic CT, and Levene's test was performed to assess benignancy and malignancy. Results : Twelve SPNs were confirmed to have malignant pathology. There were no significant differences between benign and malignant nodules with respect to peak enhancement (p=0.787), net enhancement (p=0.135), or slope of enhancement (p=0.698). The maximal enhancement ratio was increased in malignancy compared to benignancy, but the difference was not statistically significant (p=0.094). Conclusion : In our study, the hemodynamic characteristics of dynamic CT were not significantly different between benign and malignant nodules. Therefore, long-term studies of larger patient samples are required to confirm our findings.

• Journal of the Korean Society of Radiology
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• v.13 no.2
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• pp.201-207
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• 2019

This study has evaluated whether the method of using the combination of different risk group, according to K-TIRADS classification and K-TIRADS classification in thyroid ultrasonography is useful in a differential diagnosis of benign and malignant nodules. The subject was patients underwent thyroid ultrasonography and retrospective analysis were performed based on the results of fine needle aspiration cytology. A chi-square test was performed for the difference analysis of the score system in K-TIRADS and different risk group according to the benign and malignant of thyroid nodule. The optimized cut off value was determined by the K-TIRADS score and different risk group to predict malignant nodule through ROC curve analysis. In the differential verification result of K-TIRADS and different risk group, according to the classification of benign and malignant nodule group each showed significant difference statistically(p=.001). In the point classification according to K-TIRADS for the prediction of benign and malignant in ROC curve analysis showed AUC 0.786, Cut-off value>2(p=.001), and in the different risk group, it was decided as AUC 0.640, Cut-off value>2(p=.001). When discovering the nodule in thyroid ultrasound, it is considered that the K-TIRADAS which helps in identifying benign and malignant thyroid nodules, it is considered to be helpful in the differential diagnosis of thyroid nodules, than the classification system according to Different risk group, and when applying the classification system according to K-TIRADS, it is considered that it can reduce unnecessary fine needle aspiration cytology and could be helpful in finding the malignant nodules early.

• Journal of the Korea Computer Graphics Society
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• v.24 no.5
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• pp.31-39
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• 2018

In this paper, we propose an automated method for the ground-glass nodule(GGN) classification using GGN-Net based on intensity, texture, and shape-enhanced images in chest CT images. First, we propose the utilization of image that enhances the intensity, texture, and shape information so that the input image includes the presence and size information of the solid component in GGN. Second, we propose GGN-Net which integrates and trains feature maps obtained from various input images through multiple convolution modules on the internal network. To evaluate the classification accuracy of the proposed method, we used 90 pure GGNs, 38 part-solid GGNs less than 5mm with solid component, and 23 part-solid GGNs larger than 5mm with solid component. To evaluate the effect of input image, various input image set is composed and classification results were compared. The results showed that the proposed method using the composition of intensity, texture and shape-enhanced images showed the best result with 82.75% accuracy.

• Journal of the Korean Society of Radiology
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• v.18 no.5
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• pp.419-427
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• 2024

The objective of this study is to analyze and evaluate the diagnostic performance and utility of elastography and artificial intelligence program in distinguishing between benign and malignant thyroid nodule. In a hospital outpatient clinic, we performed thyroid ultrasound from January 2023 to June 2024, and retrospectively analyzed 126 patients who performed elastography, S-detect, and fine needle aspiration cytology(FNAC) because nodules were found. The analysis of differences based on cytology results showed statistically significant differences in age, nodule size, echogenicity, nodule orientation, margins, shape, presence of calcification, posterior shadowing, K-TIRADS ultrasound interpretation, S-detect results and elasticity contrast index. The ROC curve analysis determined a cut off value for the elasticity contrast index at 2.32, with diagnostic concordance rates of 0.66 for expert interpretation, 0.49 for S-detect, and 0.67 for the elasticity contrast index, indicating superior diagnostic performance with elastography. Thus, elastography may ge used as an adjunct tool to minimize unnecessary repeat examinations and the frequency of tissue biopsies in the diagnosis of thyroid nodules.

• Tuberculosis and Respiratory Diseases
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• v.43 no.4
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• pp.500-518
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• 1996

Background : The solitary pulmonary nodule(SPN) presents a diagnostic dilemma to the physician and the patient. Many clinical characteristics(i.e. age, smoking history, prior history of malignancy) and radiological characteristics( i.e. size, calcification, growth rate, several findings of computed tomography) have been proposed to help to determine whether the SPN was benign or malignant. However, most of these diagnostic guidelines are based on the data collected before computed tomography(CT) has been introduced and lung cancer was not as common as these days. Moreover, it is not well established whether these guidelines from western populations could be applicable to Korean patients. Methods : We had a retrospective analysis of the case records and radiographic findings in 114 patients presenting with SPN from Jan. 1994 to Feb. 1995 in Seoul National University Hospital, a tertiary referral hospital. Results : We observed the following results ; (1) Out of 113 SPNs, the etiology was documented in 94 SP IS. There were 34 benign SP s and 60 malignant SPNs. Among which, 49 SPNs were primary lung cancers and the most common hi stologic type was adenocarcinoma. (2) The average age of patients with benign and malignant SPNs was $49.7{\pm}12.0$ and $58.1{\pm}10.0$ years, respectively( p=0.0004), and the malignant SPNs had a striking linear propensity to increase with age. (3) No significant difference in the hi story of smoking was noted between the patients with benign SPNs($13.0{\pm}17.6$ pack- year) and those with malignant SPNs($18.6{\pm}25.1$ pack-year) (p=0.2108). (4) 9 out of 10 patients with prior history of malignancy had malignant SPNs. 5 were new primary lung cancers with no relation to prior malignancy. (5) The average size of benign SPNs($3.01{\pm}1.20cm$) and malignant SPNs($2.98{\pm}0.97cm$) was not significantly different(p=0.8937). (6) The volume doubling time could be calculated in 22 SPNs. 9 SPNs had the volume doubling time longer than 400 days. Out of these, 6 were malignant SPNs. (7) The CT findings suggesting malignancy included the lobulated or spiculated border, air- bronchogram, pleural tail, and lymphadenopathy. In contrast, calcification, central low attenuation, cavity with even thickness, well-marginated border, and peri nodular micronodules were more suggestive for benign nodule. (8) The diagnostic yield of percutaneous needle aspiration and biopsy was 57.6%(19/33) of benign SPNs and 81.0%(47/58) of malignant SPNs. The diagnostic value of sputum analysis and bronchoscopic evaluations were relatively very low. (9) 42.3%(11/26) of SPNs of undetermined etiology preoperatively turned out to be malignant after surgical resection. Overall, 75.4%(46/61) of surgically resected SPNs were malignant. Conclusions : We conclude that the likelihood of malignant SPN correlates the age of patient, prior history of malignancy, some CT findings including lobulated or spiculated border, air-bronchogram, pleural tail and lymphadenopathy. However, the history of smoking, the size of the nodule, and the volume doubling time are not helpful to determent whether the SPN is benign or malignant, which have been regarded as valuable clinical parameters previously. We suggest that aggressive diagnostic approach including surgical resection is necessary in patient with SPNs.

• The Journal of the Korea Contents Association
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• v.16 no.5
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• pp.290-297
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• 2016

This study analyzed the features of the nodules requiring a fine needle aspiration, which were found in thyroid ultrasonography of the employee health check-up examinees. Based on the fine needle aspiration results, over 1 cm nodules or those implying malignancy on the ultrasonography were categorized into the 1st group. Whereas, regardless of the size the fine needle aspiration results implying malignancy on the ultrasonography were categorized into the 2nd group. In the 1st group, 15.8% were malignant, and in the 2nd group, 28% were malignant. The findings implying malignancy were statistically significant. However, even though the nodules were larger than 1 cm, when the nodules were not accompanied by a high risk factor and showed a spongiform structure in the ultrasonographic results, most of them were benign, and a fine needle aspiration was not required. The ultrasonographic findings are important rationales in making a decision on whether or not a fine needle aspiration is required for thyroid nodules. Currently, the fine needle aspiration for thyroid nodules is commonly performed when the size of the nodule is larger than 1 cm, even though it has a spongiform structure, to relieve the patient's anxiety. However, if ultrasonographic findings of thyroid are correctly understood in differentiating malignant from benign nodules, unnecessary fine needle aspiration can be avoided.