• Proceedings of the Korea Information Processing Society Conference
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• 2021.05a
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• pp.282-284
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• 2021

최근 4차 산업혁명으로 의료빅데이터 기반으로 한 AI 기술이 급속도로 발전하고 있다. 특히, 의료영상을 기반으로 병변을 탐색, 분활 및 정량화 그리고 자동진단 및 예측 관련된 기술이 AI 제품으로 출시되고 있다. AI 기술개발은 많은 학습데이터가 요구되며, 임상검증에 단일기관에서 2개 이상 기관의 검증이 요구되고 있다. 그러나 아직까지도 단일기관에서 학습용 데이터와 테스트, 검증용 데이터를 달리하여 기술개발에 활용하고 있다. 본 논문은 AI 기술개발에 필요한 영상데이터에 대한 표준화된 데이터셋 변환 및 관리를 위한 시스템에 대해 기술한다. 다기관 데이터를 수집하기 위해서는 각 기관의 의료영상 데이터 수집 및 저장하는 기준이 명확하지 않아 표준화 작업이 필요하다. 제안한 시스템은 기관 또는 다기관 연구 그룹의 의료영상데이터를 표준화하여 저장할 수 있을 뿐만 아니라 의료영상 뷰어 및 의료영상 리스트를 통해 연구자가 원하는 의료영상 데이터 셋을 검색하여 다양한 데이터셋으로 제공할 수 있기 때문에 수집 및 변환 그리고 관리까지 지원할 수 있는 시스템으로 영상기반의 머신러닝 연구에 활력을 불어넣을 수 있을 것으로 기대하고 있다.

• Proceedings of the Korea Water Resources Association Conference
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• 2021.06a
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• pp.56-56
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• 2021

하천단면이나 하상변동 추적 등 하천공간정보는 유량이나 강우 등 수문시계열 정보와 더불어 계획홍수위 산정이나 하천구조물 신설로 인한 하천의 변화를 추적하는 데 있어 근간을 이루는 주요 정보로 국가차원의 유지 및 관리가 필요하다. 국내의 하천공간정보는 RIMGIS, WAMIS, 하천 일람, WINS와 같은 웹기반 시스템에서 정보화 되어 관리되고 있다. 그러나, RIMGIS는 여러 가지 문제점을 노정하고 있어 개선을 적극적으로 검토해볼 시점이라고 볼 있다. 우선, RIMGIS는 구축이 10년 이상된 기술로 구성되어 온라인 시스템 실행속도가 느리고, 물관리 일원화 와중에 관리주체가 불분명해진 상태이며, 제공되는 정보도 하천망이나 유역 정도로 차원 및 정확도도 낮고 활용도 및 현행화도 부족한 상태이다. 또한 공간정보 관리 DB표준으로 효율적인 관계형 구조 대신 하천대장 등을 수치화한 개념의 레이어 단위의 주제도로 관리하다보니 자료중복이 불가피하여 시스템이 무겁고, 자료간 연관검색이 거의 불가하고, 신속한 하천지형 변화 업데이트가 어려운 상태이다. 최근 진행되고 있는 RIMGIS 개선 사업은 여전히 종래의 레이어 단위의 주제도들을 추가하거나 개정하는 데 머물고 있는 상태이다. 이러다 보니 현재 우리나라의 대표적인 하천정보시스템인 RIMGIS의 실무 활용도는 낮은 것으로 알려져 있다. 가장 실무활용도를 저하시키고 현행화 상의 문제로 지적되는 부분은 하천정비기본계획 수립 시 발생한 공간자료 관리 부실이다. 현재 RIMGIS에서는 하천기본계획보고서만 PDF 형태로 제공할 뿐, 실제 지형자료는 과업을 수행한 설계사에 개별 보관되어 활용도뿐만아니라 망실의 우려가 높은 상황이다. 본 연구에서는 하천기본계획수립 시 측량되는 단면을 포함한 다양한 공간자료를 관계형으로 표준화 DB에 효율적으로 저장할 수 있게 하는 방안을 제시하고자 한다.

• Journal of the Korean Society of Food Science and Nutrition
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• v.34 no.4
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• pp.544-548
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• 2005

The objective of this study was to determine the effect of die temperature and dimension on extraction pattern, extract yield, and crude saponin content of extruded white ginseng. The extrusion variables were die temperature $(110\;and\;120^{\circ}C)$ and die dimension (3 holes with 1.0 mm, 2 holes with 2.0 mm, and 1 hole with 3.0 mm diameter). The browness and redness were indicator of active components in ginseng extract. Both were used to evaluate the effect of die temperature and die dimension on release pattern and release rate constant. Browness and redness of extract achieved its lowest value at die temperature $110^{\circ}C$ and 2 holes with 2.0 mm diameter, indicating the lowest extraction rate constant. Extract yield highly increased by extrusion treatment. Extract yield and crude saponin content were the highest at die temperature $120^{\circ}C$ and 1 hole with 3.0 mm diameter. In conclusion, extrusion process has contributed significantly in improvement of release rate of its active components.

• Korean Journal of Microbiology
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• v.46 no.3
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• pp.233-239
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• 2010

Four genes (yqfR, yfmL, ydbR, deaD) were identified as putative DEAD-box RNA helicase genes in the genomic sequence of Bacillus subtilis by homology search. To understand the function of these genes, each of the genes was deleted and the constructed strains were tested for their growth charateristics at different temperatures. The growth rate of ydbR deletion mutant ($T_d$=53 min) was a little bit reduced at $37^{\circ}C$ as compared to that of wild type strain (CU1065). But the growth rate of other three (yqfR, yfmL, deaD) deletion mutants ($T_d$=30-40 min) is nearly equal to the growth rate of wild type ($T_d$=32 min). On the other hands, the growth rate of deletion mutants were reduced at $22^{\circ}C$ in order of yqfR ($T_d$=151 min), yfmL ($T_d$=214 min), ydbR ($T_d$=343 min), which showed cold-sensitive phenotype. The deletion mutant of deaD ($T_d$=109 min) grew equally as compared to the growth rate ($T_d$=102 min) of the wild type at $22^{\circ}C$ and did not show cold-sensitive growth. Double, triple and quadruple deletion mutants of these genes were constructed, and growth rate of these mutants were measured at various temperature conditions ($22^{\circ}C$, $37^{\circ}C$, $42^{\circ}C$) using LB broth. Multiple deletion mutations showed more severe cold-sensitive growth than single deletion mutations, and double deletion of ydbR and yfmL ($T_d$=984 min) showed most cold-sensitive growth than any other double mutants. Such a cold-sensitive growth of these mutations is quite similar to the result of csdA or srmB deletion in E. coli and suggested that physiological role of ydbR and yfmL is related with ribosome assembly.

• Science of Emotion and Sensibility
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• v.14 no.4
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• pp.571-580
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• 2011

The purpose of this study was to evaluate the effects of secondary task such as sending text message (STM) and searching navigation (SN) using the variable indicating control of vehicle ((Medial-Lateral Coefficient of Variation, MLCV), (Anterior-Posterior Coefficient of Variation, APCV)) and motion signal (Jerk-Cost function, JC). Participants included 50s taxi drivers; 14 males and 14 females. Participants were instructed to keep a certain distance (30m) from the car ahead with constant speed (80km/hr or 100km/hr). Experiement consisted of driving alone for 1minute and driving with secondary task for 1minute. Both MLCV and APCV were significantly increased during Driving + Sending Text Message(STM) and Driving + Searching Navigation(SN) than Driving only. Also, JC was increased during Driving + STM and Driving + SN than Driving only. In this study, we found that even in the experts group who are taxi driver and have 25 years driving experience, the smoothness of motion is decreased and the control of vehicle is disturbed when they were performing secondary tasks like sending text message or searching navigation.

• Journal of Oral Medicine and Pain
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• v.31 no.4
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• pp.297-316
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• 2006

The increasing tendency of medical disputes is one of the remarkable social phenomena. Especially we must not overlook the phenomenon that production and circulation of information related to medical accidents is increasing rapidly through the internet. In this research, we evaluated the web sites which provide the information related to medical accidents using the keyword "medical accidents" in March 2006, and classified the 28 web sites according to the kinds of establishers. We also analyzed the contents of the sites, and checked and compared the current status of the web sites and problems that have to be improved. Finally, we suggested the possible solutions to prevent medical accidents. The detailed results were listed below. 1. Medical practitioners, general public, and lawyers were all familiar with and prefer the term "medical accidents" mainly. 2. In the number of sites searched by the keyword "medical accidents", lawyer had the most sites and medical practitioners had the least ones. 3. Many sites by general public and lawyers had their own medical record analysts but there was little professional analysts for dentistry. 4. General public were more interested in the prevention of medical accidents but the lawyers were more interested in the process after medical accidents. The sites by medical practitioners dealt with the least remedies of medical accidents, compared with other sites. 5. General public wanted the third party such as government intervention into the disputes including the medical dispute arbitration law or/and the establishment of independent medical dispute judgment institution. 6. In the comparison among the establishers of web sites, medical practitioners dealt with the least examples of medical accidents. 7. The suggestion of cases in counseling articles related to dental accidents were considered less importantly than the reality. 8. Whereas there were many articles about domestic cases related to the bloody dental treatment, in the open counseling articles the number of dental treatment regarding to non insurance treatment was large. 9. In comparing offered information of medical accidents based on the establishers, general public offered vocabularies, lawyers offered related laws and medical practitioners offered medical knowledge relatively. 10. They all cited the news pressed by the media to offer the current status of domestic medical accidents. Especially among the web sites by general public, NGOs provided the plentiful statistical data related to medical accidents. 11. The web sites that collect the medical accidents were only two. As a result of our research, we found out that, in the flood of information, medical disputes can be occurred by the wrong information from third party, and the medical practitioners have the most passive attitudes on the medical accidents. Thus, it is crucial to have the mutual interchange and exchange of information between lawyer, patients and medical practitioners, so that based on clear mutual comprehension we can solve the accidents and disputes more positively and actively.

• Journal of KIISE:Information Networking
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• v.29 no.3
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• pp.286-298
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• 2002

The Remote Procedure Call(RPC) has been traditionally used for Inter Process Communication(IPC) among precesses in distributed computing environment. As distributed applications have been complicated more and more, the Mobile Agent paradigm for IPC is emerged. Because there are some paradigms for IPC, researches to evaluate and compare the performance of each paradigm are issued recently. But the performance models used in the previous research did not reflect real distributed computing environment correctly, because they did not consider the evacuation elements for providing security services. Since real distributed environment is open, it is very vulnerable to a variety of attacks. In order to execute applications securely in distributed computing environment, security services which protect applications and information against the attacks must be considered. In this paper, we evaluate and compare the performance of the Remote Procedure Call with that of the Mobile Agent in IPC paradigms. We examine security services to execute applications securely, and propose new performance models considering those services. We design performance models, which describe information retrieval system through N database services, using Petri Net. We compare the performance of two paradigms by assigning numerical values to parameters and measuring the execution time of two paradigms. In this paper, the comparison of two performance models with security services for secure communication shows the results that the execution time of the Remote Procedure Call performance model is sharply increased because of many communications with the high cryptography mechanism between hosts, and that the execution time of the Mobile Agent model is gradually increased because the Mobile Agent paradigm can reduce the quantity of the communications between hosts.

• Journal of Nutrition and Health
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• v.43 no.2
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• pp.105-113
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• 2010

Ixeris dentata var. albiflora Nakai, a herbal plant, is often used to make a strong stomach as an antiphlogistic used when dyspepsia and to improve appetite in Korea and China. And also it is used for adult diseases such as diabetes and liver diseases as Korean traditional medicine. In this study, the composition and DPPH radical scavenging activities of the root of Ixeris dentata var. albiflora Nakai and its effects on cell viability on vero and chang cells were investigated. Moisture, crude ash, crude protein and crude lipid were 79.14, 2.49, 8.28 and 2.56 g/100 g respectively. The highest mineral content was K. The major free sugars were glucose, fructose and sucrose. Major fatty acid are linoleic acid, palmic acid and linolenic acid. Major amino acids were glutamic acid, arginine and aspartic acid and the total contents of amino acids were 28.12 mg/g. The methanol extracts were further fractionated with n-hexane, chloroform, ethylacetate, butanol and water to get an active fraction. In addition, cell viabilities in each fraction were determined. Methanol extract, butanol, and aqueous fraction showed strong survival rates in vero cell and chang cell viability test, and hexane, chloroform, and ethylacetate fraction were examined for toxin in a cell. The root of Ixeris dentata var. albiflora Nakai had scavenging activities against DPPH radicals in a dose-dependent assay. Ethylacetate fraction's SC50 was $6.8\{\mu}g/mL$, very strong DPPH radical scavenging activities, but water fraction did not show any activity.

• Korean Journal of Plant Resources
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• v.30 no.2
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• pp.144-151
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• 2017

This study examined the anti-inflammatory and whitening effects of Amaranth (Amaranthus spp L.) seed extract. Amaranthus spp L. seeds were extracted using 70% ethanol and then fractionated sequentially with n-hexane, dichloromethan, ethyl acetate and butanol. For the study of anti-inflammatory activity in RAW 264.7 cells, EtOAc fraction of Amaranthus spp L. seeds significantly inhibited nitrogen oxide production as well as the protein level of iNOS. Furthermore, EtOAc fraction of Amaranthus spp L. seeds inhibited expression of $TNF-{\alpha}$, PGE2 and the protein level of COX-2 in a dose-dependent manner. Inaddition, the tyrosinase inhibitory activities of the Amaranthus spp L. seed 70% ethanol extract and subfractions were also measured to see if these extracts can be used as an ingredient for whitening cosmetics. Tyrosinase is an oxidase that is a rate-limiting enzyme for controlling the production of melanin. Therefore, tyrosinase inhibitors have become increasingly important in cosmetics and medical products with regards to hyperpigmentation. EtOAc fraction of Amaranthus spp L. seeds showed mushroom tyrosinase inhibitory activity in a dose-dependent manner. This activity was more potent than that of a positive control cynandione A. These results suggest that Amaranthus spp L. seeds may be a valuable natural ingredient for the food and cosmetics industries.

• Korean Journal of Community Nutrition
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• v.7 no.5
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• pp.664-674
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• 2002

청소년을 위한 영양 웹사이트의 컨텐츠 개발을 목적으로 사이버 영양정보 이용 현황과 요구도를 파악하고자 서울, 대전, 광주, 대구의 4개 대도시의 남녀 중고등학생 1262명을 임의로 선정하여 2000년 9월부터 10월에 걸쳐 설문지 조사를 실시하고 분석한 결과는 다음과 같다. 조사대상의 인터넷/PC통신의 이용시간은 전체 하루 평균137.0 $\pm$ 100.6분으로 나타났고 남학생이 여학생보다 평균 20.2분 길었다(p<0.05) 영양정보 급원의 이용 비중은 TV/라디오가 가장 컸고(3.69 $\pm$ 1.48) 인터넷/PC통신의 비중은 남녀, 중고생간의 차이 없이 매우 낮았다(1.30 $\pm$1.53). 인터넷/PC통신의 이용은 주로 게임 오락, 채팅이나 사교, 숙제자료를 찾기 위해서였으며 학교 공부 이외의 정보와 지식을 얻기 위한 활용도는 낮았다. 조사대상 중 인터넷/PC통신을 통해 영양정보 습득 경험이 있는 비율은 전차의 34.5%였으며 여학생(38.3%)이남학생(30.3%)보다 높았다(p<0.01). 영양정보 습득을 위해 인터넷/PC퉁신 이용 빈도는 응답자의 72%가 한 달에 1회 이하였으나, 한 달에 4회 이상 이용자도 10.9%나 되었다. 이용 목적은 ‘숙제를 위하여’가 가장 많았고 ‘자신의 건강’ 또는 ‘다이어트를 위함’이 그 다음 순이었다. 이용한 영양 웹사이트들의 전반적인 만족도는 ‘보통’의 수준(3.05 $\pm$ 0.92)이었으며 별로 또는 전혀 만족하지 않는 비율이 29.2%나 되었는데, 개선점으로 ‘정보의 빈약’(36.3%), ‘내용의 지루함과 흥미 부족’ (23.8%), ‘접속 속도의 느림’ (20.7%)의 순이었고, ‘내용의 난해도’는 전체의 13.0%가 지적하였다. 영양 컨텐츠의 내용에 대한 요구도를 조사한 결과 청소년 수준에 맞도록 쉽고 구체적이며 (71,8%), 새로운 정보의 빠른 업데이트(60.6%), 그리고 화면구성면에서는 쉽게 찾아 들어올 수 있고(88.6%) 복잡하지 않은 화면(61.9%)과 캐릭터를 많이 쓰는 것(51.1%)에 대한 요구도가 높았다. 한편 인터넷/PC통신을 통한 영양상담 경험은 남녀나 중고생간의 차이 없이 전반적으로 매우 적었으며(8.1%) 그중 91%가 한 달에 1회 이하로 저조한 상담 빈도를 보였다. 상담목적은 ‘자신의 건강’, ‘숙제’, ‘다이어트’, ‘가족의 건강을 위해’ 순으로 나타났으며, 상담결과에 대한 만족도는 ‘보통’보다 낮은 수준으로서(2.53 $\geq$ 1.01) ‘별로 또는 전혀 만족하지 않는’ 비율이 45.9%로 나타났다. 영양상담사이트의 개선점으로는 답변의 빈약함(43.2%), 난해성(22.7%), 느린 답변(22.7%) 등을 지적하였으며 친절하고 충분한 답변에 대한 요구도가 크게(48.7%) 나타났다. 조사대상들의 영양정보 습득이나 영양상담의 접속 경로는 주로 검색엔진을 통해서였으며 야후와 다음이 가장 많이 이용되었다.