• The korean journal of orthodontics
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• v.35 no.5 s.112
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• pp.351-360
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• 2005

This study aimed to investigate the effects of indomethacin on distribution and expression of COX-2 and IGF-1 in the mandibular condyle ofi growing dogs and to examine the number of chondroclasts around the mineralization zone indomethacin inhibits prostatlandin $E_2$ production in the tissue by inhibiting synthesis of cyclooxygenase 2. Prostaglandin $E_2$ stimulates insulin-like growth factor synthesis. Insulin-like growth factor stimulates growth of mandibular condylar cartilage. Eight mongrel dogs. aged 13-14 weeks, were divided into 4 groups. Group 1 and group 2 were administered indomethacin 2 mg/Kg/day orally two times a day for 7 days and 14 days respectively. Group 3 were administered indomethacin 8mg/Kg/day orally 2 times a day for 14 days, and 4he control group were administered a placebo. The mandibular condyle heads were sectioned in $5{\mu}m$ thickness The specimens were stained with H-E staining. COX-2 immunohistochemical staining and IGF-1 immunohistochemical staining and examined under microscope. After TRAP staining, the number of chondroclasts were calculated The observed results were as follows: Indomethacin inhibited expression and distribution of COX-2 and IGF-1 on the proliferative zone of condylar cartillage. Indomethacin decreased the number of chondroclastes on the mineralization zone by a time-dependent manner (P<0.05). Indomethacin inhibited expression and distribution of IGF-I by a dose and time-dependent manner. These results show that indomethacin inhibited expression and distribution of COX-2 and IGF-1 on the proliferative zone of condylar cartilage and decreased the number of chondroclasts and suggests that when indomethacin is administered for a long time, condyle growth could be delayed.

• Journal of Korean Ophthalmic Optics Society
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• v.17 no.3
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• pp.285-291
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• 2012

Purpose: This study was conducted to research any effect on visual function related to accommodation by VDT work. Methods: The refraction power, accommodative lag, accommodative facility, relative accommodation, amplitude of accommodation and blink rate were measured before and after VDT work for 2 hours on 48 university students (16 males and 32 females), without abnormal accommodative function and systemic and ocular disease, who had never undergone corrective eye surgery. All examinations were performed with distant refraction, and a survey was conducted on the items related to subjective symptoms of VDT syndrome. Results: After 2 hours of VDT work, refractive power increased by 0.23 D, the amount of change in accommodative lag were $0.17{\pm}0.42D$ in the right eye and $0.23{\pm}0.47D$ in the left eye (t=2.26, p=0.03). There were statistically significant differences. Both the accommodative facility and relative accommodation and amplitude of accommodation were decreased after work. However, blink rate were increased. After VDT work, 33.4% of the subjects showed subjective symptoms of asthenopia and 33.3% of them showed shoulder pain. Conclusions: As a result, the accommodative lag increased in response to the two hours of VDT work, and overall accommodative functions were decreased. In addition, as symptoms of providing visual strain, asthenopia showed the most prominent subjective symptoms.

• Journal of Korean Ophthalmic Optics Society
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• v.18 no.3
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• pp.271-277
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• 2013

Purpose: The purpose was to study the corneal refractive power changes associated with the wearing of everted silicone hydrogel soft lenses. Methods: The corneal refractive power and corneal astigmatism were measured using corneal topographer (CT-1000, Shin-nippon Co., Japan) for checking change of corneal refractive power and objective refractive error was measured by auto-refractometer (Natural vision-K 5001, Shin-nippon Co., Japan). We measured at baseline and 1 week after lens wearing. Results: The correcting of corneal refractive power could be effective in low myopia. It's more effective to the higher power of greatest meridian of cornea and the more corneal astigmatism. 73% of subjects' refractive error was decrease less than 1 D and 17% of the subjects had an reverse effect (increase) occurs. The reduction of objective refractive error was more effective when cornea refractive power was great or corneal astigmatism was much. Conclusions: Pressure which the everted silicone hydrogel lens to the cornea could be caused. It occurred as the degrees of corneal power, corneal astigmatism and objective refractive error differences. Selection of an appropriate subject is important considering difficulty of changing the parameters of the lens.

• Journal of Korean Ophthalmic Optics Society
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• v.17 no.4
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• pp.403-410
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• 2012

Purpose: The purposes of this study are to investigate accommodative response among emmetropes, spectacle wearer and contact lens wearer, and correlation between refractive error and accommodative respons for each group. Methods: The 72 subjects(144 eyes) who do not have any ocular diseases were participate in this study. Subjects were categorized into emmetropes, spectacle wearer and contact lens wearer by refractive error using closed-field auto-refractometer. We measured dominant eye, naked/habitual visual acuity and refractive error of monocular/binocular vision of refractive error for far/near distance with open-field auto-refractometer and calculated accommodative lag. Results: There were no significant difference of accommodative lag between right and left eye dominant and non-dominant eye, monocular and binocular vision, and spectacle lens wearer and contact lens wearer, However the accommodative lag of binocular vision was severe than monocular vision at near. The lag of myopia was larger than emmetropes, and male was larger than female. Significant correlation was found between refractive error and accommodative lag in total subjects and the same result was found in emmetropes and contact lens wearer. However there were no significant correlation in the spectacle wearer. Conclusions: There were significant difference between emmetrops and myopes in terms of accommodative lag, however accommodative lag of spectacle wearer was not different with contact lens wearer in myopes. There were also significant correlation between refractive error and accommodative lag in emmetropes and contact lens wearer, but the accommodative lag of spectacle wearer was not significantly correlated with refractive error.

• Journal of the korean academy of Pediatric Dentistry
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• v.27 no.4
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• pp.564-572
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• 2000

We decided among extraction, orthodontic traction and autotransplantation such as direction and position of unerupted tooth, degree of developing root apex, eruption space, being of supernumerary tooth or odontoma or cyst when tooth impacted. Autotransplantation is considered when orthodontic traction is unrealistic or when tooth movement can absorb root of neighbor tooth. The prognosis for successful autotransplantation is dependent on a number of factors such as root development, surgical technique, patient's age, endodontic treatment, time and type of splinting, preservation of periodontal ligament and storage medium. Especially when severe osseous defect is being, bone graft considered for reducing of mobility and for assisting recovery. In all cases, chief complaint is unerupted tooth and various causing factors were supernumerary, odontoma, ectopia and so on. Before autotransplantation, space regaining was done if needed and demineralized freezed dried bone and autogenous bone graft was done when there is severe osseous defect by extraction of supernumerary tooth or odontoma. Splinting was removed after 2-3weeks At 3-4weeks after autotransplantation, endodontic treatment was decided. At follow up check, normal recovery was done and there was no inflammatory or replacement root resorption in periapical radiograph.

• The korean journal of orthodontics
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• v.35 no.2 s.109
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• pp.106-115
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• 2005

This study was aimed to investigate the effects of indomethancin on physiologic root resorption and to examine the dental pulp and tissue changes around the resorbing teeth 13-14 week old six mongrel dogs were divided into 3 groups, two experimental groups administered indomethacin 2mg/kg/day and 8mg/kg/day orally two times a day for 14 days respectively. and control group administered a placebo The deciduous incisors showing root resorption were selected. fixed for 24 hrs in $10\%$ formalin solution. demineralized in $10\%$ EDTA solution. Invested in paraffin and sectioned in $5{\mu}m$ thick sections. The preparations were stained with H&E staining and Masson's trichrome staining and examined under the light microscope Observation revealed that deciduous root resorbing tissue resembles inflammatory tissue and accompanies bore remodelling. The dental pulp was formal except the area near root resorption. well organized columnar odontoblasts layer under the predentin, anud the odontoblasts near root resorption were cuboidal or flat cells in the disrupted layer under the predentin. Indomethacin administered group showed a partial decrease in the number of odontoclasts and nucleus But there was no sign of pulp change by indomethacin. These results suggest that indomethacin inhibits recruitment of odontoclasts partially and that of osteoclasts more. and so when it is administered for long periods deciduous root resorption can be delayed and eruption of the successor can be delayed for a short period.

• Journal of Veterinary Clinics
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• v.31 no.2
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• pp.137-140
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• 2014

A Maltese (case 1) and a Labrador Retriever (case 2) presented with urinary incontinence. General conditions were good and screening tests, including a complete blood count, serum chemistry and radiography, were performed. Excretory urography was conducted, and fluoroscopy was performed for case 1 and computed tomography was performed for case 2. The dogs were diagnosed as right extramural ectopic ureter in case 1 and bilateral intramural ectopic ureter in case 2. We performed surgical corrections, including a neoureterocystostomy for extramural ectopic ureter and neoureterostomy for intramural ectopic ureter. After surgery, the dogs were catheterized with an indwelling catheter for 3 days. Urinary incontinence improved completely and the clinical outcomes were good. The choice of adequate surgical procedure is important for correcting ectopic ureters in canines.

• Proceedings of the Korea Water Resources Association Conference
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• 2009.05a
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• pp.1908-1912
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• 2009

유량자료는 물의 순환과정을 규명하고 효율적인 수자원 개발 및 이수 치수 계획 등에 매우 귀중하게 이용된다. 그러나 이러한 유량자료를 확보하는 데는 많은 시간과 경비 등이 요구되기 때문에 주요 수위의 유량측정자료로 수위-유량관계 곡선식(Stage-Discharge Curve)을 개발하여 유량자료를 환산하고 있다. 따라서 수위-유량관계 곡선식의 신뢰도는 유량자료의 품질에 절대적인 영향을 미치는 요인으로 작용된다. 수문학을 연구하는 많은 학자들은 고품질의 유량자료를 생산하여 신뢰성 있는 곡선식을 개발하고자 유량측정 방법과 기준, 장비개량 등에 관한 연구를 수행하고 있다. 측정하고자 하는 기기별 측정 성과에 대한 연구 자료가 거의 없이 국내에 보급된 다양한 유속측정기기를 사용하여 유량자료를 생산하여 활용하고 있다. 본 연구에서는 규격화된 콘크리트 수로에 일정한 유량을 흘려보내고 다양한 측정기기를 이용하여 유속을 측정하였다. 그리고 이 측정성과를 이용하여 유량을 산정하고 비교분석하였다. 실험을 위해서 국내에서 일반적으로 사용되고 있는 측정기기로 마그네틱유속계(Electromagnetic Current Meter), 휴대용유량계(Flow Meter), 프라이스유속계(USGS Type AA Current Meter), 갈수기용유속계(USGS Pygmy Meter)등의 장비를 사용하였으며, 동일한 조건에서 유량을 얻음으로 측정 기기가 제시하는 유량을 알 수 있었다. 비교검토에 적용하고자 측정한 수심으로는 0.25m, 0.30m, 0.35m, 0.40m의 4개 Case로 진행이 되었으며, 측정방법으로는 도섭법(Wading Measurement)에 의하거나 케이블웨이(Cableway), 교량법(Bridge Measurement), 보트법(Boat Measurement)등이 있으나, 신뢰성과 정확도를 높이기 위해 도섭법으로 수면에서 0.6d 지점의 유량측정방법(1점법)을 적용하였다. USGS Type AA Current Meter, USGS Pygmy Meter는 유속측정기기의 검교정을 받았으므로 다른 실험유속측정치의 비교를 위한 기준값으로 사용하였다. 따라서 국내에서 널리 사용되는 측정기기(Electromagnetic Current meter, Flow Meter, USGS Type AA Current Meter, USGS Pygmy Meter)별 검토 결과 프라이스유속계를 기준으로 마그네틱유속계는 ${\pm}$10% 이상, 갈수기용 유속계 및 휴대용 유량계는 ${\pm}$5% 미만의 차이가 있음을 확인할 수 있었다.

• Journal of Korean Ophthalmic Optics Society
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• v.9 no.2
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• pp.223-231
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• 2004

In most previous studies, the assessment of accommodative convergence to accommodative stimulus (AC/A) ratio was commonly made by measuring gradient AC/A ratio. This study deals with the proximal convergence/accommodation(PC/A)ratio measured by comparing values of the gradient AC/A ratio and the calculated AC/A ratio to prevail the clinical use of the AC/A ratio. Visual acuities of All 124 subjects had been corrected to at least 1.0 with either eye through their habitual refractive correction and the MEM dynamic retinoscopy was performed to estimate their accommodative response. And then the PC/A ratio was calculated by making use of the calculated AC/A ratio and the gradient AC/A ratio. This study showed that the difference between the mean calculated AC/A ratio and the mean gradient AC/A ratio in subgroups may be attributable to proximal convergence. Consequently, further studies on proximity cues including the PC/A ratio could be helpful to prevail the clinical use of the AC/A ratio.

• Korean Journal of Clinical Laboratory Science
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• v.50 no.3
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• pp.370-374
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• 2018

Subclavian steal syndrome is a type of obstructive artery disease caused by severe stenosis and occlusion of a left proximal subclavian artery or brachiocephalic trunk. The resulting vertebro-basilar insufficiency symptoms are due to retrograde blood flow from the contralateral vertebral and basilar arteries into the low-pressure ipsilateral upper extremity vessels. For that reason, patients usually experience dizziness or arm ischemic symptoms. Neurointervention is an effective treatment for ischemic stroke, including the subclavian artery stenosis. This paper reports a patient with subclavian steal syndrome who had a vertebral artery Doppler waveform change in duplex sonography and a 12 mmHg difference in interarm systolic blood pressure. A stenotic lesion of the subclavian artery was treated effectively by inserting a precise stent. The follow up examination showed that the vertebral artery Doppler waveform change disappeared and recovered and that the 12 mmHg difference in interarm systolic blood pressure decreased to 5 mmHg after treatment.