• Title/Summary/Keyword: 강도 조기 평가

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Brain Atrophy and White Matter Lesions on Magnetic Resonance Imaging in Alzheimer's Disease (알쯔하이머 치매 환자의 뇌자기공명영상(腦磁氣共鳴影像)에 나타난 뇌위축(腦萎縮)과 뇌백질병변(腦白質病變)에 대한 연구)

  • Woo, Jong Inn;Kim, Ju Han
    • Korean Journal of Biological Psychiatry
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    • v.3 no.2
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    • pp.203-210
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    • 1996
  • Objects : To investigate the relationship between the age of onset with the atrophy and the white matter hyperintensities observed in the brain MRI of Alzheimer patients. Methods : The authors measured volumetrically cortical and ventricular brain atrophy and rated semiquantitatively white matter signal hyperintensities in nine presenile and 18 senile Alzheimer patients, who were matched for dementia severity, according to NINCDS-ADRDA criteria and in age-matched 10 presenile and 11 senile control subjects. Results : Presenile Alzheimer patients showed significantly greater cortical and ventricular atrophy indices(p<0.05) but no difference in white matter hyperintensity scores compared to the age-matched control group. On the contrary, senile Alzheimer patients showed significantly greater white matter hyperintensity scores(p<0.05) but no difference in cortical and ventricular atrophy indices compared to the age-matched control group. Conclusion : An earlier onset was related to marked brain atrophy with less white matter lesions and a later onset is related to marked white matter lesions with less brain atrophy in Alzheimer's disease. Our results suggested the passible difference in the pathophysiology between the presenile and the senile-onset Alzheimer's disease.

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Elasto-Magnetic Sensor-Based Local Cross-Sectional Damage Detection for Steel Cables (Elasto-Magnetic 센서를 이용한 강재 케이블 국부 단면 감소 손상 탐지)

  • Kim, Ju-Won;Nam, Min-Jun;Park, Seung-Hee;Lee, Jong-Jae
    • Journal of the Korean Society for Nondestructive Testing
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    • v.31 no.4
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    • pp.360-366
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    • 2011
  • The Elasto-magnetic sensor is applied to detect the local cross-sectional loss of steel cables in this study while it was originally developed for measuring the tensile force in the previous works. To verify the feasibility of the proposed damage detection technique, steel bars which have 4-different diameters were fabricated and the output voltage value was measured at each diameter by the E/M sensor. Optimal input voltage and working point are chosen so that the linearity and resolution of results can ensure through repeated experiments, and then the E/M sensor was measured the output voltage values at the damage points of steel bar specimen that was applied the 4 types of damage condition based on the selected optimal experimental condition. This proposed approach can be an effective tool for steel cable health monitoring.

The functional imaging to Diagnose Acute Cerebral infarction Comparing between CT Perfusion and MR Diffusion Imaging (급성 뇌경색 진단을 위한 CT관류영상과 MR확산영상의 비교)

  • Kim, Seon-Hee;Eun, Sung-Jong;Rim, Chae-Pyeong
    • Journal of the Korean Society of Radiology
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    • v.6 no.1
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    • pp.19-26
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    • 2012
  • It is very important for early diagnosis and therapy with ischamic cerebral infarction patients. This study was to know the ischemic penumbra lesion which compared CT-perfusion and diffusion weighted MRI(DWMRI) with acute cerebral infarction patients. 12 acute cerebral infarction patients had performed perfusion CT and performed DWMRI. Perfusion images including cerebral blood volume(CBV), cerebral blood flow(CBF), time to peak(TTP) and mean transit time(MTT) maps obtained the values with defect lesion and contralateral normal cerebral hemisphere and DWMRI was measured by signal intensity and compared of lesion size between each perfusion map. All perfusion CT maps showed the perfusion defect lesions in all patients. There were remarkable TTP and MTT delay in perfusion defect lesions. The lesions on CBF map was the most closely correlated with the lesions on DWMRI. The size of perfusion defect lesions on TTP and MTT map was larger than that of lesions on DWMRI, suggesting that MTT map can evaluate the ischemic penumbra. Perfusion CT maps make it possible to evaluate not only ischemic core and ischemic penumbra, but also hemodynamic status in the perfusion defect area. These results demonstrate that perfusion CT can be useful to the diagnosis and treatment in the patients with acute cerebral ischemic infarction.

Beneficial effects of ton-bag and wire-steel pallet on postharvest handling of onion and the cost evaluation (톤백 및 와이어철제파렛트 이용에 따른 양파의 수확후관리 효율성 증대와 경제성 평가)

  • Kwon, Young-Deuk
    • Food Science and Preservation
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    • v.24 no.7
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    • pp.915-922
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    • 2017
  • This study aimed in onion production by evaluating cost and labor efficiencies of onion storage methods using either a ton-bag or a wire-steel pallet. New methods using ton-bag and wire-steel pallets were developed and applied to postharvest tasks, such as harvest packaging, transportation, and storage. The storage parameters evaluated for their effect on the logistics of onion production were: working duration, working hours, and cost expenditure. The longitudinal tensile strength of the ton-bag developed in this study was 16% higher than that of the conventional ton-bag. The wire-steel pallet developed in this study had 10% more storage capacity in a low-temperature storage room, and its truck loading capacity was more than doubled compared to that of the conventional steel pallet. There was no difference in the wasting rate during bulk storage between the newly developed wire-steel pallet and the conventional steel pallet, for 500 kg of onions. However, the bulk storage of 1,000 kg of onions using the wire-steel pallet was not found to be suitable, because the wasting rate of onions stored using the wire-pallet was 3.7% higher than that of onions stored using a conventional steel pallet. The time and the total investing costs for the bulk method decreased by 50.1% and 46.1%, respectively, compared to those for conventional harvest. In the bulk storage using the wire-steel pallet, the total storage cost decreased by 28.8%. Thus, it is estimated that we could have saved 18.3 billion won if the wire-steel pallet method about 30% of the total onion production (1,298,749 M/T) in 2016.

Effect of Biochar Treatment on the Growth Characteristics of Q. variabilis for the Restoration of Post-fire Forest Areas (산불피해지 복원을 위한 바이오차 처리가 굴참나무 묘목 생육에 미치는 영향)

  • Yu Gyeong Jung;So Jin Kim;Ju Eun Kim;Jeong Hyeon Bae;Won Seok Kang;Young Geun Lee;Ki Hyung Park
    • Journal of Korean Society of Forest Science
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    • v.112 no.3
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    • pp.290-302
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    • 2023
  • The aim of this study was to examine the changes in the initial tree growth characteristics of Q. variabilis planted in forest fire-damaged areas treated with soil moisturizers such as biochar and to identify the factors that affect tree growth. To evaluate the effectiveness of soil moisture treatment in the area planted with QV, an experimental plot was created according to the treatment method (spread and mix) and treatment ratio (0, 4, and 40 t/ha). The survival rate of QV was 20% higher in the treatment plot than in the control plot. The height and root collar diameter (RCD)growths of QV were high on the northern slope with spread treatment and on the southern slope with mix treatment. The relative growth rate (RGR) according to the soil moisturizer treatment method was higher in the mix treatment, showing a significant difference in RCD. The northern slope had a higher RGR and significant growth rate. This suggests that the growth improvement effect may depend on the soil moisturizer treatment method. The aspect or treatment method affectsthe drying conditions of the soil, which in turn affects its moisture content or nutrient dynamics. The present research results can be used to establish soil moisturizer treatment standards that are suitable for growth purposes. In addition, this study demonstrates that biochar treatment can be considered as an effective alternative to boost biomass and facilitate early restoration of forest fire-damaged areas.

Study on the Growth and Flowering Characteristics according to the Sowing Time of Genetic Resources of Cruciferae (십자화과(Cruciferae) 유전자원의 파종시기에 따른 생육 및 개화특성 조사)

  • Kwang-Soo Kim;Da-Eun Kwon;Ji-Eun Lee;Young-Lok Cha;Yong-Ku Kang
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2020.08a
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    • pp.52-52
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    • 2020
  • 유채(Brassica napus L.)는 식용유 생산을 목적으로 재배되며, 1975년에는 26.8천ha가 재배되어 연간 생산량이 34.7천톤이 생산되었으나, 외국으로부터 값싼 식용유의 대량수입으로 재배면적이 급격하게 감소되었다. 그러나 최근에 지방자치단체를 중심으로 경관용 재배면적이 증가하고 있고, 건강에 대한 관심이 높아짐에 따라 국내산 non-GM 식용유 생산을 목적으로 유채 재배면적이 급격하게 증가하고 있다. 유채의 대량생산을 위해서는 논 재배가 필수적이나 유채와 벼의 이모작 재배 시기가 겹치는 문제점이 발생하고 있어 조생종 유채의 품종개발과 함께 봄 파종이 가능한 유채의 품종 육성에 대한 요구가 매우 높다. 따라서 본 연구에서는 국내 보유 유채를 포함하는 십자화과(Cruciferae) 유전자원의 특성 평가를 통해 극조숙 유채 품종 육성을 조기에 육성하기 위해 실시하였다. 농촌진흥청 국립유전자원센터에서 분양받은 유전자원 146계통을 파종 재배하면서 핵형분석과 외부형질을 기준으로 정확한 종을 동정하였고, 각 유전자원의 생육 및 개화특성을 조사하였다. 유전자원들을 세포분석기를 이용하여 핵형을 분석한 결과, 전체 146개의 유전자원 중 유채(B. napus L.) 128계통, 갓(B. juncea Sinsk) 6계통, 배추(B. campestris Makino) 9계통, 미분류 3계통 등으로 조사되었다. 유전자원을 가을 파종(10월 22일)하였을 때 개화가 가장 빠른 계통(IT 279089)이 파종 후 137일 이후인 3월7일부터 개화가 시작되었고, 가장 늦은 계통(IT 279198)은 191일 후인 4월 30일에 개화가 시작되었다. 봄 파종(2월 4일)하였을 때 개화가 가장 빠른 계통(IT 279089)이 파종 후 79일 이후인 4월 23일부터 개화가 시작되었고 IT 279092 등 29계통은 추대와 개화가 되지 않았다. 위와 같은 연구결과를 토대로 개화시기가 빠른 유전자원을 육종을 위한 인공교배 시화분친이나 종자친으로 이용하면 지방산 품질이 좋고 극조숙성인 유채 품종의 개발이 가능할 것으로 생각된다.

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Evaluation of Neoadjuvant Chemotherapy Effect in Osteosarcoma (골육종에서 술전 항암화학요법의 효과 판정)

  • Joo, Min Wook;Kang, Yong-Koo;Yoo, Ie Ryung;Choi, Woo Hee;Chung, Yang-Guk;Kim, Dong-Hyun;Kang, Jin-Woo
    • The Journal of the Korean bone and joint tumor society
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    • v.20 no.2
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    • pp.66-73
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    • 2014
  • Purpose: Various diagnostic imaging modalities have been used to evaluate the effect of neoadjuvant chemotherapy for osteosarcoma early and noninvasively. We evaluated the effectiveness of imaging studies of plain radiographs and positron-emission tomography/computed tomography (PET/CT) in predicting neoadjuvant chemotherapy effect for osteosarcoma and tried to establish a general principle in interpretation of PET/CT parameters. Materials and Methods: Eighteen patients who underwent two cycles of neoadjuvant chemotherapy and surgical excision for osteosarcoma were enrolled. There were 13 males and 5 females, with a median age of 19 (11-63) years. Fifteen patients of 18 had the American Joint Committe on Cancer (AJCC) stage IIB. They had plain radiographs and PET/CT before and after neoadjuvant chemotherapy. The resected tumor specimens were pathologically examined to determine histological response grade using a conventional mapping method. Statistical analysis was performed to evaluate the correlation between histopathological necrosis rate, and radiographic finding category, post-chemotherapy maximum standardized uptake value (SUVmax), average standardized uptake value and metabolic tumor volume (MTV) as well as reduction rates of them. Results: Eight patients were good responders to neoadjuvant chemotherapy based on histological evaluation. Median SUVmax reduction rate was 73 (23-77) % in good responders and 42 (-32-76) % in poor responders. Median MTV reduction rate was 93.5 (62-99) % in good responders and 46 (-81-100) % in poor responders. While radiographic finding category was not different according to histological response (p=1.0), SUVmax reduction rate was significantly different (p=0.041). Difference in MTV reduction rates approached statistical significance as well (p=0.071). Conclusion: While radiographic finding category was not reliable to assess neoadjuvant chemotherapy effect for osteosarcoma, reduction rate of SUVmax was a useful indicator in this study. As parameters of PET/CT can be influenced by various factors of settings, different centers have to make an effort to establish their own standard of judgement with reference of previous studies.

Assessment of the Safe Rice Cropping Period Based on Temperature Data in Different Regions of North Korea (북한 지역별 기온 자료를 활용한 벼 안전 재배 시기 분석)

  • Yang, Woonho;Kang, Shingu;Kim, Sukjin;Choi, Jong-Seo;Park, Jeong-Hwa
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.20 no.2
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    • pp.190-204
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    • 2018
  • The probability of safe cropping and the major phenological stages in rice were assessed using daily mean temperature data from 1981 to 2016 at 27 sites in North Korea. The threshold temperatures for early marginal transplanting date (EMTD), marginal harvesting date (MHVD), safe marginal heading date (SMHD), and cumulative temperature-based heading date (CTHD) were set to be $14^{\circ}C$, $13^{\circ}C$, $22^{\circ}C$ for 40 days after heading, and cumulative temperature of $1200^{\circ}C$ to MHVD, respectively. The safe heading date (SHD) was assumed to be either SMHD or CTHD whichever was earlier. It was also assumed that the minimum requirement for the suitability of safe rice cropping was met when both SMHD and CTHD appeared along with the time period of 60 days or more from EMTD to SHD. It was analyzed that 17 sites (Kaesong, Haeju, Yongyon, Singye, Sariwon, Nampo, Pyongyang, Anju, Kusong, Sinuiju, Changjon, Wonsan, Hamhung, Pyonggang, Huichon, Supung, Kanggye) had 90% or higher probability, two sites (Yangdok, Sinpo) had 80-90% probability, and eight sites (Kimchaek, Chunggang, Chongjin, Sonbong, Changjin, Pungsan, Hyesan, Samjiyon) had less than 80% probability of the safe rice cropping. For each region, the representative EMTD, SHD, and MHVD were analyzed using the 80 percentile of total years tested. The ranges for EMTD, SHD, and MHVD were May 4 in Sariwon~May 24 in Sinpo, June 21 in Kanggye~August 11 in Haeju, and September 17 in Kanggye~October 16 in Haeju and Changjon, respectively. Time durations from EMTD to SHD and from SHD to MHVD were 67~97 days and 57~72 days, respectively, depending on the regions. This study would facilitate modeling efforts for rice yield simulation in future studies. Our results would also provide basic information for practical researches on the rice cropping system in North Korea.

A Study on the Seawater Filtration Characteristics of Single and Dual-filter Layer Well by Field Test (현장실증시험에 의한 단일 및 이중필터층 우물의 해수 여과 특성 연구)

  • Song, Jae-Yong;Lee, Sang-Moo;Kang, Byeong-Cheon;Lee, Geun-Chun;Jeong, Gyo-Cheol
    • The Journal of Engineering Geology
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    • v.29 no.1
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    • pp.51-68
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    • 2019
  • This study performs to evaluate adaptability of seashore filtering type seawater-intake which adapts dua1 filter well alternative for direct seawater-intake. This study varies filter condition of seashore free surface aquifer which is composed of sand layer then installs real size dual filter well and single filter well to evaluate water permeability and proper pumping amount according to filter condition. According to result of step aquifer test, it is analysed that 110.3% synergy effect of water permeability coefficient is happened compare to single filter since dual filter well has better improvement. dual filter has higher water permeability coefficient compare to same pumping amount, this means dual filter has more improved water permeability than single filter. According to analysis result of continuous aquifer test, it is evaluated that dual filter well (SD1200) has higher water permeability than single filter well (SS800) by analysis of water permeability coefficient using monitoring well and gauging well, it is also analysed dual filter has 110.7% synergy effect of water permeability coefficient. As a evaluation result of pumping amount according to analysis of water level dropping rate, it is analysed that dual filter well increased 122.8% pumping amount compare to single filter well when water level dropping is 2.0 m. As a result of calculating proper pumping amount using water level dropping rate, it is analysed that dual filter well shows 136.0% higher pumping amount compare to single filter well. It is evaluated that proper pumping amount has 122.8~160% improvement compare to single filter, pumping amount improvement rate is 139.6% compare to averaged single filter. In other words, about 40% water intake efficiency can be improved by just installation of dual filter compare to normal well. Proper pumping amount of dual filter well using inflection point is 2843.3 L/min and it is evaluated that daily seawater intake amount is about $4,100m^3/day$ (${\fallingdotseq}4094.3m^3/day$) in one hole of dual filter well. Since it is possible to intake plenty of water in one hole, higher adaptability is anticipated. In case of intaking seawater using dual filter well, no worries regarding damages on facilities caused by natural disaster such as severe weather or typhoon, improvement of pollution is anticipated due to seashore sand layer acts like filter. Therefore, It can be alternative of environmental issue for existing seawater intake technique, can save maintenance expenses related to installation fee or damages and has excellent adaptability in economic aspect. The result of this study will be utilized as a basic data of site demonstration test for adaptation of riverside filtered water of upcoming dual filter well and this study is also anticipated to present standard of well design and construction related to riverside filter and seashore filter technique.

Allogeneic Inlay Cortical Strut Grafts for Large Cysts or Post-curettage Cavitary Bony Defects (거대 낭종성 골병소 또는 소파 후 잔유 골 결손부에 시행한 내재형 동종 피질 지주골 이식술)

  • Chung, Yang-Guk;Kang, Yong-Koo;Kim, Chol-Jin;Lee, An-Hi;Park, Jeong-Mi;Bahk, Won-Jong;Yoo, Hyun-Ho
    • The Journal of the Korean bone and joint tumor society
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    • v.17 no.2
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    • pp.73-78
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    • 2011
  • Purpose: This study was aimed to evaluate the result of inlay cortical strut bone grafts for large cysts or cavitary bone lesions in long bones. Materials and Methods: Seven patients with large cyst or cavitary bony lesions were managed with curettage, allogeneic inlay cortical strut and cancellous bone grafts. Additional plate and screw fixations were performed in 6 patients. There were three SBCs, two FDs with secondary ABC changes, one FD and one post-cement spacer removal state. Three of them had pathologic fractures. Progression of bone healing and mechanical support and functional result were evaluated. The mean follow-up period was 25.4 months. Results: Incorporations into host bones were progressed in all, average 4.2 months in six metaphyseal regions and 5.8 months in five diaphyseal regions respectively. Full structural supports were achieved in all except one patient without any additional procedures. No allograft-related complication was developed. Mean functional score according to the MSTS criteria was 29.6 at last follow up. Conclusion: Inlay cortical strut graft provided additional mechanical stability and bone stock for screw purchase in large cyst or cavitary defects of long bones, which allow early mobilization and excellent functional outcome.