• Journal of the Korea Society of Computer and Information
• /
• v.10 no.6 s.38
• /
• pp.27-36
• /
• 2005

Finite failure NHPP models presented in the literature exhibit either constant, monotonic increasing or monotonic decreasing failure occurrence rates Per fault. This Paper Proposes reliability model using the generalized gamma distribution, which can capture the monotonic increasing(or monotonic decreasing) nature of the failure occurrence rate per fault. Equations to estimate the parameters of the generalized gamma finite failure NHPP model based on failure data collected in the form of interfailure times are developed. For the sake of proposing shape parameter of the generalized gamma distribution, used to the special pattern. Data set, where the underlying failure process could not be adequately described by the knowing models, which motivated the development of the gamma or Weibull model. Analysis of failure data set for the generalized gamma modell, using arithmetic and Laplace trend tests . goodness-of-fit test, bias tests is presented.

• Tuberculosis and Respiratory Diseases
• /
• v.43 no.1
• /
• pp.63-68
• /
• 1996

Background: Interferon-$\gamma$ has various biologic effects, including antiviral effect, antitumor proliferative effect, activation of macrophage and B lymphocyte, and increased expression of major histocompatibility complex. Especially, antitumor proliferative effect of interferon-$\gamma$ has already been proved to be important in vivo as well as in vitro. And, clinical studies of interferon-$\gamma$ have been tried in lung cancer patients. However, the mechanism of antitumor effect of interferon-$\gamma$ has not yet been established despite of many hypotheses. "Necrosis" is a type of cell death which is well known to occur in the circumstances of severe stresses. In contrast, "apoptosis" is another type of cell death which occurs in such biological circumstances as embryonic development, regression of organs, and self-tolerance of lymphocytes. And, apoptosis is an active process of cell death in which cells are dying with fragmentations of their cytoplasms and nuclei. And, in the process of apoptosis the DNAs of cells are cleaved between nucleosomes by unidentified endonuclease and therefore DNAs of apoptotic cells result in a typical electrophoresis pattern known as DNA ladder pattern. Recently it has been suggested that cytotoxic effect of interferon-$\gamma$ occurs via apoptosis. To elucidate the mechanism of antitumor cytotoxic effect of interferon-$\gamma$, we microscopically observed a lung cancer cell line, A549 which was treated with interferon-$\gamma$. We observed A545 treated with interferon-$\gamma$ was dying fragmented. And so, we performed this study to find out that the mechanism of antitumor cytotoxic effect of interferon-$\gamma$ be apoptosis. Method: We treated A549, human lung cancer cell line with various concentration of interferon-$\gamma$ and quantified its cytotoxic effect of various periods, 24 hours, 72 hours and, 120 hours by MTT(dimethylthiazolyl diphenyltetrazolium bromide) bioassay. Also, after we treated A549 with 100 units/mi of interferon-$\gamma$ for 120 hours, we observed the pattern of cell death with inverted microscope and we extracted DNAs from the dead A549 cells and observed the pattern of 1.5% agarose gel electrophoresis with ethidium bromide staining. Result: 1) Cytotoxic effect of interferon-$\gamma$ on A549: For the first 24 hours, threre was little cytotoxic effect and for between 24 hours and 72 hours, there was the beginning of cytotoxic effect and for 120 hours there was increased cytotoxic effect. 2) Pattern of A549 cell death by interferon-$\gamma$: We observed with inverted microscope that A549 cells were dying fragmented. 3) DNA ladder pattern of gel electrophoresis: We observed DNA ladder pattern of gel electrophoresis of extracted DNAs from dead A549 cells. Conclusion: We concluded that the mechanism of interferon-$\gamma$induced cytotoxicity on lung cancer cell line, A549 be via apoptosis.

• The Journal of Engineering Geology
• /
• v.9 no.3
• /
• pp.253-265
• /
• 1999

Physical properties of Paleozoic sedimentary rocks in Gabsan formation in Jechon area were obtained by both geophysical well log methods and core property measurements, and the similarity and difference shown between the well log and core log responses were analyzed. The physical properties obtained are natural gamma, resistivity and density. From the difference in density response between the well log and core measurement, the need of correction for natural gamma effect on density log was strongly suggested. And fairly good correlation was obtained between well log and core properties, and among natural gamma, resistivity and density by applying natural gamma correction on density log. It is noted that shale in Gabsan formation reveals very high density, even higher than the density of adjacent non-porous limestone.

• Journal of radiological science and technology
• /
• v.29 no.3
• /
• pp.125-132
• /
• 2006

The PET/CT scanner is an evolution in image technology. The two modalities are complementary with CT and PET images. The PET scan images are well known as low resolution anatomic landmak, but such problems may help with interpretation detailed anatomic framework such as that provided by CT scan. PET/CT offers some advantages-improved lesion localization and identification, more accurate tumor staging. etc. Conventional PET employs tranmission scan require around 4 min./bed position and 30 min. for whole body scan. But PET/CT scanner can reduced by 50% in whole body scan. Especially nowadays PET scanner LSO scintillator-based from BGO without septa and operate in 3-D acquisition mode with multidetectors CT. PET/CT scanner fusion problems solved through hardware rather than software. Such device provides with the capability to acquire accurately aligned anatomic and functional images from single scan. It is very important to effective detection from gamma ray source in PETdetector. And can be offer high quality diagnostic images. So we have study about detection processing of PET detector and high quality imaging process.

• Journal of Advanced Navigation Technology
• /
• v.23 no.5
• /
• pp.400-407
• /
• 2019

In this paper, the shadow detection and reconstruction method are proposed using intrinsic image, which does not change the essential characteristics under the influence of various illuminance, and multi-scale gamma correction. The shadow detection was estimated by the pixel change information between a grayscale and an intrinsic image of the color image, and the brightness of the image were adjusted by gamma correction in the shadow restoration process. Multi-scale gamma correction is performed for each channel of a color image due to the fact that the saturation can be changed by nonlinear adjustment to individual pixel values. Multi-scale gamma values are estimated based on the information of the crossed edge between shadows and non-shadowed regions in the color image, as a result, the shadows are reconstructed by correcting different region features with multi-scale gamma values. Experimental results show that the proposed method effectively reconstructs shadows in a single natural image.

• Communications for Statistical Applications and Methods
• /
• v.4 no.2
• /
• pp.533-540
• /
• 1997

일반화 감마분포(generalized gamma distribution)에서 지표모수(index parameter)에 대한 추론은 생존시간(lifetime)과 관련한 모형의 선택문제에서 매우 중요하다. 이에 대한 정확한(exact) 추론법은 알려져 있지 않다. 본 연구에서는 이에 대한 점근적(asymptotic) 검정법으로 소표본에서도 우도비 검정에 비해 효율이 뛰어난 Bartlett 검정을 제안하고, 이의 요율적 수행을 위한 대체 모형으로 부터의 누율계산(cumulant computation) 법을 제시하였다. 또한 실제자료에 대해 본 논문에서 제시한 누율계산과정을 이용하여 Bartlett 검정을 실시한 결과 기존의 우도비 검정과는 상당히 큰 차이가 남을 확인하였다. 따라서 모형의 선택 등의 문제에서 제안된 방법은 소표본의 경우에 더욱 효율적이라 할 수 있다.

• Journal of the Institute of Electronics Engineers of Korea SP
• /
• v.45 no.2
• /
• pp.65-73
• /
• 2008

The characterization process for the accurate color reproduction in mobile phone with camera and LCD is popular. The camera and LCD characterization, gamut mapping process is necessary to map the camera's input color stimulus, CIEXYZ value, into the LCD's output color stimulus. Each characterization is the process estimating the relation between input and output signals. In case of LCD, because of output device, the output color stimulus for the arbitrary input signal can be measured by spectro-radiometer However, in the camera, as the input device, the characterization is an inaccurate and needs the manual works in the process obtaining the output signal because the input signal can not be generated. Moreover, after gamut mapping process, the noise is increased because the optimized gamma tone curve of camera for the noise is distorted by the characterization. Thus, this paper proposed the system of obtaining the output signal of camera and the method of gamma correction for the noise. The camera's output signal is obtained by RGB values of patches from captured the color chart image. However, besides the illumination, the error for the location of the chart in the viewfinder is generated when many camera modules are captured the chart. The method of correcting the position to correct the error from manual works. The position of camera is estimated by captured image. This process and moving of camera is accomplished repeatedly, and the optimized position can be obtained. Moreover, the lightness curve of camera output is corrected partly to reduce the noise from the characterization process.

• Communications for Statistical Applications and Methods
• /
• v.4 no.3
• /
• pp.753-763
• /
• 1997

컴퓨터의 발전에 따른 MCMC를 비동질적 포아송 과정에 이용하였다. 베이지안 추론에서 조건부 분포를 가지고 사후분포를 결정하는데 있어서의 계산 문제를 고려하였다. 특히 분포가 이중지수, 곰페르츠, 랄리, 감마, 그리고 검벨인 일반 순서통계량 모형에 대하여 깁스 샘플링과 메트로폴리스 알고리즘을 활용한 베이지안 계산과 모형선택을 제시하였다.

• Proceedings of the Korea Contents Association Conference
• /
• 2013.05a
• /
• pp.161-162
• /
• 2013

본 논문에서는 Mental ray 렌더러를 통해 렌더링 된 이미지의 색감과 사실적인 빛의 감쇠효과를 위해 사용되는 Color Management를 활용한 Linear Work Flow 작업과정을 제시하고 그 이론적인 배경을 설명하고자 한다. 디지털로 사용되는 대부분의 이미지 포맷은 모든 모니터에서 동일한 색감을 표현하기 위해 sRGB라는 표준화된 형식을 사용하고 있다. 하지만 Mental ray는 기본적으로 감마 커브가 1.0으로 이루어진 이미지를 렌더링한다. sRGB가 가지고 있는 2.2의 감마커브와 차이가 발생함에 따라 사용자가 원하는 색감을 얻어내기 어렵다. 반면에 Color Management를 활용해 렌더링 된 이미지의 감마 커브를 수정해주면 3D 소프트웨어로 사용 된 텍스쳐의 원본 색감을 렌더링 후에도 유지할 수 있다. 또한 라이팅의 감쇠(Decay)와 산란에도 영향을 주어 보다 풍부한 색감의 이미지를 얻게 된다. 본 연구에서는 Autodesk Maya의 Mental Ray를 이용해 실험을 하고 Color Management를 활용한 이미지와 그렇지 않은 이미지를 비교 분석한다. 연구의 범위는 제품 렌더링을 위한 스튜디오 라이팅 기법으로 한정하였다.

• The Korean Journal of Applied Statistics
• /
• v.35 no.2
• /
• pp.311-325
• /
• 2022

For count responses, the situation of excess zeros often occurs in various research fields. Zero-inflated model is a common choice for modeling such count data. Bayesian inference for the zero-inflated model has long been recognized as a hard problem because the form of conditional posterior distribution is not in closed form. Recently, however, Pillow and Scott (2012) and Polson et al. (2013) proposed a Pólya-Gamma data-augmentation strategy for logistic and negative binomial models, facilitating Bayesian inference for the zero-inflated model. We apply Bayesian zero-inflated negative binomial regression model to longitudinal pharmaceutical data which have been previously analyzed by Min and Agresti (2005). To facilitate posterior sampling for longitudinal zero-inflated model, we use the Pólya-Gamma data-augmentation strategy.