• The Journal of Dong Guk Oriental Medicine
• /
• v.9
• /
• pp.111-125
• /
• 2000

Galwhahaejungtang has been used to alcoholic disease. Object of This study is examining the effect of Galwhahaejungtang and exercise on variation of total cholesterol, HDL-cholesterol, triglyceride, free fatty acid, BUN, Creatinine in rat with alcohol administration. METHODS AND MATERIALS Fifty four rats were divided into four groups. 1. The group of rat with alcohol administration and no treatment 2. The group of rat with alcohol and Galwhahaejungtang administration 3. The group of rat with alcohol administation and exercise 4. The group of rat with alcohol, Galwhahaejungtang administration and exercise Serum of rat were obtained after 2 weeks and 4 weeks. RESULTS 1. The level of total cholesterol was decreased in the group of rat with Galwhahaejungtang administration and exercise after 2 weeks. After 4 weeks, the level of total cholesterol was significantly decreased in the group of rat with Galwhahaejungtang administration and exercise. 2. The level of HDL-cholesterol was significantly increased in the group of rat with exercise after 2 weeks. After 4 weeks, the level of HDL-cholesterol was significantly increased in the group of rat with no treatment and with Galwhahaejungtang administration. 3. The level of try glyceride was significantly decreased in the group of rat with exercise after 2 weeks. After 4 weeks, the level of tryglyceride was significantly decreased in the group of rat with Galwhahaejungtang administration. 4. The level of free fatty acid was significantly decreased in the group of rat with Galwhahaejungtang administration after 2 weeks. After 4 weeks, the level of free fatty acid was significantly decreased in the group of rat with Galwhahaejungtang administration and with Galwhahaejungtang administration and exercise. 5. The level of BUN was significantly decreased in the group of rat with Galwhahaejungtang administration and exercise after 2 weeks. After 4 weeks, the level of BUN was significantly decreased in the group of rat with exercise. 6. The level of creatinine was significantly decreased in the group of rat with Galwhahaejungtang administration and exercise. After 4 weeks, the level of creatinine was significantly decreased in the group of rat with exercise and with Galwhahaejungtang administration and exercise. CONCLUSION Based on these results, it is considered that Galwhahaejungtang administration and exercise has an accelerating effect on alcohol metabolism.

• The Journal of Internal Korean Medicine
• /
• v.22 no.3
• /
• pp.495-501
• /
• 2001

Alcohol withdrawal syndrome includes two or more of the following symptoms: autonomic hyperactivity, increased hand tremor, insomnia, nausea or vomiting, hallucinations of illusions, psychomotor agitation, anxiety, grand mal seizures. Symptoms are usually relieved by administering brain depressant. In oriental medicine, Ju sang correspond to alcohol withdrawal syndrome. Galhwahaesung-tang has been used for the treatment of Ju sang. The authors treated 2 cases of alcohol withdrawal syndome with Galhwahaesung-tang and symptoms are markedly improved. So, We report these case with a brief review of related literatures.