• Title/Summary/Keyword: 간절제술

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Partial Hepatectomy in a Canine Hepatocellular Carcinoma (부분 간절제술을 통한 개의 간세포암종 치료예)

  • 이충호;최재훈;정성목;김완희;김대용
    • Journal of Veterinary Clinics
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    • v.18 no.2
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    • pp.170-173
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    • 2001
  • Primary hepatocellular carcinomas are rare in dogs. A 12-year-old 5.4 kg female Poodle was referred to the Veterinary Medical Teaching Hospital with abdominal distension and mild anorexia. In this case, an extensive soft tissue mass was clearly palpable in the upper abdomen and radiography revealed a spherical mass of soft tissue density in the abdomen but its origin was not clear. In following an exploratory laparotomy, a partial hepatectomy was performed. Surgical complications were minimal. The survival time was seven months before dyspnea lead to a sudden and rapid decline.

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Psychological Characteristics of Living Liver Transplantation Donors using MMPI-2 Profiles (MMPI-2를 이용한 생체 간 공여자들의 심리적 특성에 대한 연구)

  • Lee, Jin Hyeok;Choi, Tae Young;Yoon, Seoyoung
    • Korean Journal of Psychosomatic Medicine
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    • v.27 no.1
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    • pp.42-49
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    • 2019
  • Objectives : Living donor liver transplantation (LDLT) is a life-saving therapy for patients with terminal liver disease. Many studies have focused on recipients rather than donors. The aim of this study was to assess the emotional status and personality characteristics of LDLT donors. Methods : We evaluated 218 subjects (126 male, 92 female) who visited Daegu Catholic University Medical Center from August 2012 to July 2018. A retrospective review of their preoperative psychological evaluation was done. We investigated epidemiological data and the Minnesota Multiphasic Personality Inventory-2 questionnaire. Subanalysis was done depending on whether subjects actually underwent surgery, relationship with the recipient, and their gender. Results : Mean age of subjects was $32.19{\pm}10.91years$. 187 subjects received LDLT surgery (actual donors) while 31 subjects didn't (potential donors). Donor-recipient relationship included husband-wife, parent-children, brother-sister etc. Subjects had statistical significance on validity scale L, F, K and all clinical scales compared to the control group. Potential donors had significant difference in F(b), F(p), K, S, Pa, AGGR, PSYC, DISC and NEGE scales compared to actual donors. F, D and NEGE scales were found to be predictive for actual donation. Subanalysis on donor-recipient relationship and gender also showed significant difference in certain scales. Conclusions : Under-reporting of psychological problems should be considered when evaluating living-liver donors. Information about the donor's overall psychosocial background, mental status and donation process should also be acquired.

The Effect of Gamisoyo-san Intravenous Pharmacopuncture on Restoration of Liver Function after Partial Hepatectomy in SD Rat (가미소요산 혈맥약침이 부분 간절제술을 시행한 Rat의 간기능 회복에 미치는 영향)

  • Lee, Chan;Yun, Jung-Hun;Yim, Yun-Kyoung
    • The Journal of Korean Medicine
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    • v.36 no.1
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    • pp.22-32
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    • 2015
  • Objectives: This study researched the effect of Gamisoyo-san intravenous pharmacopuncture on restoration of liver function after partial hepatectomy in SD rat. Methods: Twelve rats were randomly divided into three groups: control group (n=4) underwent partial hepatectomy, saline group (n=4) was injected $1m{\ell}$ saline after partial hepatectomy, Gamisoyo-san group (n=4) was injected with 10mg/kg Gamisoyo-san after partial hepatectomy. Liver function and liver regeneration ratio were measured on the seventh day after partial hepatectomy. Results: The results show that the AST, AST and ALT level in Gamisoyo-san group was significantly lower than those of control group and saline group(P<0.05) Conclusion: In partial hepatectomy model, Gamisoyo-san intravenous pharmacopuncture seems to significantly promote the restoration of liver function.

Effects of Carcinogens and Partial Hepatectomy on the Nitrogen Utilizing and the Xenobiotic Metabolizing Enzymes in the Hepatic Tissues of Rats (발암원과 부분간절제술 처리에 의한 백서 간 조직중 질소이용계 및 이물질 대사계 효소의 변화)

  • 박상철;김응국;곽상준;이건욱;김수태
    • Environmental Mutagens and Carcinogens
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    • v.8 no.1
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    • pp.22-34
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    • 1988
  • The biochemical changes of the hepatic tissues, induced by the carcinogen treatment such as diethylnitrosamine and acetamidofluorene in combination with the partial hepatectomy after Solt and Farber, were determined for the characterization of the induction of the proliferative capacity and the environmental adaptability of the carcinogenic tissues during the malignant transformation process. For the study of the proliferative capacity of the tissues, the activities of the enzymes, related with the nitrogen trapping mechanism, such as glutamine synthetase and gamma-glutamyltranspeptidase, were monitroed, while the cintents of cytochrome P450's and their isozymic patterns as well as the activities of the glutathione S-transferase were determined in the function of time after the hepatocarcinogenic stimuli.

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Cirrhosis after Liver Lobectomy Managed with Traditional Korean Medical Treatment: A Case Report (간세포암의 부분 간절제술 후 한방치료로 복수를 동반한 간경변 증상이 호전된 환자 증례보고)

  • Kim, Hyo-rin;Jeong, Hye-ryon;Jang, Chul-yong;Woo, Chan;Ha, Ye-jin;Moon, Goo;Baek, Dong-gi
    • The Journal of Internal Korean Medicine
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    • v.36 no.3
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    • pp.410-418
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    • 2015
  • Objectives The purpose of this study is to report the possibility of treatment of liver cirrhosis with traditional Korean medical treatment. Methods A 57-year-old man diagnosed with hepatocellular carcinoma and liver cirrhosis was admitted to Wonkwang University Oriental Medical Hospital in August 2014. He underwent liver lobectomy and later experienced abdominal pain, anorexia, and insomnia. To control cirrhotic ascites and prevent relapses, he opted to receive HangAmDan-B (HAD-B) and cultivated wild ginseng herbal acupuncture therapy. Results After treatment, the volume of ascites decreased and the patient&’s symptoms such as abdominal pain and anorexia improved. Conclusions This report suggests that HAD-B and cultivated wild ginseng herbal acupuncture therapy may play a therapeutic role in liver cirrhosis occurring after liver lobectomy.

A Human Case of Hepatic Resection for Liver Fascioliasis In Korea (간내 간충병에 대한 간절제술 1예)

  • Kim, Hong-Jin;Roh, Sung-Kyun;Shim, Min-Chul;Kwun, Koing-Bo;Lee, Heun-Ju;Chang, Jae-Chun;Lee, Tae-Sook
    • Journal of Yeungnam Medical Science
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    • v.7 no.1
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    • pp.165-171
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    • 1990
  • Human Fasciola hepatica infection is a rare entity involving infestation of the liver and biliary tree with adult flukes. which can result in hepatitis. cirrhos is and biliary tract inflammation. obstruction and lithiasis. The patient had the typical diagnostic tetrad of fever. eosinophilic leukocytos is. tender hepatomegaly and fluke ova in the stools. Theatment consistes of Emetine hydrochloride administration for hepatic involvement and common bile duct exploration for removal of flukes. with cholecystectomy for associated cholelithiasis. The combination of medical and surgical therapy cal be expected to produce an arrest of this infection. The removed liver revealed eggs of the fasciols species in the intrahepatic bile duct. The clinical history. pathological findings and treatment of this case were described.

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Effects of acute LeeKwaDoo administration on liver regeneration induced by partial hepatectomy in rats (부분 간절제술을 시행한 랫드에서 간재생에 관한 이과두주 급성투여에 따른 영향)

  • Cho Jin-Youn;Song Ji-Yae;Ahn Jae-Bum;Kim Hyun-Seok;Kim Min-Su;Im Hyun;Lim Jun-Sung;Shin Dong-Seok;Kim Hyun-Chul;Jung Ki-Soo;Shin Myung-Kyun;Lee Min-Jae
    • Korean Journal of Veterinary Service
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    • v.29 no.1
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    • pp.55-63
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    • 2006
  • Alcoholism and alcohol abuse are major public health concerns. This is linked to the injury of many organs, especially liver. Experiments were peformed to know the acute effects of LeeKwaDoo (LKD) induced by two-third partial hepatectomy (PH) in rats. In liver samples, regeneration parameters and histological assessment were performed. For the blood biochemical study, the blood were assayed with AST, ALT. The portal branch of liver lobes was ligated in the male Sprague-Dowley rats, two-thirds partial hepatectomies were also performed. It was estimated bodyweight and relative liver weight for the index of liver mass. For the marker of blood chemistry, we investigate the serum sample of rats and demonstrated the level of AST, ALT. Remaining tissues of liver developed as microscopic structures. Resection of the lobes in PH+LKD group resulted in a marked change of liver weight, blood chemistry and histological changes. The initiation of the proliferative response in PH group stimulated as well as reduction of the liver mass. On the other hands, the Initiation of the proliferative response in PH+LKD group delayed. Eventually, both PH group and PH+LKD group was restored relative liver weigh after 7 day. In conclusion, the acute adminstration of LKD seems to inhibit the initial response of liver regeneration through alcohol effects.

The Mean Transit Time of the CBD and the Afferent Loop Using $^{99m}Tc-DISIDA$ Scintigram in Truncal Vagotomy (미주신경간절제술에 있어서 $^{99m}Tc-DISIDA$ 신티그램을 이용한 총수담관 및 Afferent loop의 평균지연시간)

  • Moon, Tae-Yong;Kim, Dong-Soo
    • The Korean Journal of Nuclear Medicine
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    • v.22 no.2
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    • pp.199-203
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    • 1988
  • The authors observed functional change of the CBD and the afferent loop with the transit time of $^{99m}Tc-DISIDA$ scintigram in patients treated by the surgical operation of gastric ulcers and cancer at Busan National University Hospital from June, 1987 to April, 1988. So authors estimated the time between the peak activity of the CBD and the afferent loop (TCA), the half transit time of the CBD activity (t 1/2 CBD) and the half transit time of the afferent loop activity (t 1/2 A-loop) in 9 patients undergone truncal vagotomy, who have no specific symptoms at 2 to 6 months after the operation, 5 patients undergone the operation without truncal vagotomy, and 7 persons as a control group. The results were as follows: I) In control group, the mean TCA, t 1/2 CBD and t 1/2 duodenum were $8.6{\pm}9.0$ min, $38.7{\pm}17.3$ min. and $28.6{\pm}10.9$ min, respectively. 2) In the operation group without truncal vagotomy, the mean TCA, t 1/2 CBD and t 1/2 A-loop were $10.0{\pm}7.1$ min. $48.2{\pm}22.3$ min. and $39.4{\pm}26.7$ min. respectively. 3) In the operation group with truncal vagotomy, the mean TCA, t 1/2 CBD and t 1/2 A-loop were $15.0{\pm}8.7$ min., $36.1{\pm}16.5$ min. and $42.6{\pm}24.4$ min, respectively. From the above results, we concluded that the transit time of the CBD and the afferent loop is not affected by truncal vagotomy.

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