• The Journal of Korean Academic Society of Nursing Education
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• v.20 no.1
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• pp.108-117
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• 2014

Purpose: The purpose of this study was to develop and validate health care providers' counseling manual in mobile application for lifelong health care among patients with chronic hepatitis B. Methods: The mobile application was developed using a prototyping approach and system developing life cycle method, evaluated by users for their satisfaction with the counseling manual and experts for the quality of the manual. To evaluate application of the counseling manual, knowledge and counselor self-efficacy of the subjects were measured and compared before and after application of the counseling manual. Results: There were statistically significant increases in knowledge and counselor self-efficacy in the user group. A mobile application with high accessibility and applicability including information and counseling factors can promote counseling competence of the nurse as health care provider caring chronic hepatitis B patients. Conclusion: The results of this study indicate that the counseling manual in mobile application is effective in increasing knowledge and counselor self-efficacy among nurses to promote lifelong health care among patients with chronic hepatitis B. Therefore, it can be usefully utilized in the field of nursing for patients with chronic hepatitis B as a nursing intervention.

• Laboratory Medicine Online
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• v.7 no.3
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• pp.94-102
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• 2017

Malaria, tuberculosis, and hepatitis are common and notorious infectious diseases in Myanmar. Despite intensive efforts to control these diseases, their prevalence remains high. For malaria, which is a vector-borne disease, a remarkable success in the reduction of new cases has been achieved. However, the annual number of tuberculosis cases has increased over the last few decades, and the prevalence of chronic viral hepatitis infection has been high in Myanmar and other nearby countries. Early detection and prompt treatment are crucial to control these diseases. We have devoted our research efforts to understanding the status of these infectious diseases and working towards their eventual elimination for the last four years with the support of the Korea International Cooperation Agency. In the modern era, an infection that develops in one geographical area can spread globally because national borders do not effectively limit disease transmission. Our efforts to understand the status of infectious diseases in Myanmar will benefit not only Myanmar but also neighboring countries such as Korea.

• Laboratory Medicine and Quality Assurance
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• v.40 no.2
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• pp.51-69
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• 2018

As part of the immunoserology program of the Korean Association of External Quality Assessment Service, we organized two trials on the external quality assessment of hepatitis viral markers in 2016 and 2017. The hepatitis viral antigens and antibodies program consisted of 10 test items. We delivered two and three types of pooled sera specimens to 965 and 965 institutions for the first and second trials of external proficiency testing in 2016, respectively. The number of participating laboratories was 915 (94.8%) and 913 (95.0%) in the first and second trials in 2016, respectively. We also delivered three kinds of pooled sera specimens to 936 and 1,015 institutions for the first and second trials of external proficiency testing in 2017, respectively. The number of participating laboratories was 920 (98.3%) and 996 (98.1%) in the first and second trials in 2017, respectively. The most commonly tested items were hepatitis B surface antigen, followed by the antibodies to hepatitis B surface antigen, anti-hepatitis C virus, hepatitis B envelope antigen, antibodies to hepatitis B envelope antigen, anti-hepatitis A virus and antibodies to hepatitis B core antigen. The most frequently used methods for detecting viral markers were the chemiluminescence immunoassay and the electrochemiluminescence immunoassay, but they yielded a few-false positive results due to the matrix effect. The immunochromatographic assay yielded false-negative results for anti-hepatitis A virus due to low sensitivity. Continuous improvement in the quality of viral hepatitis testing through participation in the survey seems necessary.

• Pediatric Infection and Vaccine
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• v.4 no.2
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• pp.240-256
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• 1997

Purpose: To evaluate the hepatitis B vaccination program which has been conducted since 1980, Korea. Methods: This study was carry out self reported questionnaire and serologic test covering 2,072 elementary school students who were born between 1980 and 1987, selected by cluster sampling. The HBV serologic markers (HBsAg, Anti-HBs and Anti-HBc) were tested by radioimmunoassay (RIA). The contents of questionnaire include demographic data of students and parents, vaccination status, vaccination frequency, vaccination age, past history of mother's HBV test. Results: 1) The HBsAg positive rates by sex showed 3.7% for male and 2.7% for female, representing an average rate of 3.4%. The HBsAg positive rates by age group showed 5.6% for 13 years and l.5% for 6 years, representing a tendency of lowering rate as ages being younger. 2) The pre-natal HBV test rate was 10.2%, while post-natal HBV test rate was 42.5%. The test showed that the parents' educational level being higher than others, the pre- and post-natal HBV test showed higher rates. In case the fathers occupation being office worker, the post-natal HBV test showed a higher rate compared with other occupation. 3) Overall vaccination rate was 82.6%, complete vaccination rate 69.8%, booster injection rate 42.8%. The vaccination rate, complete vaccination rate and booster injection rate increased as the age being younger. If the educational level of parents were higher, the vaccination rate, complete vaccination rate and booster injection rate showed higher rates. Younger students showed younger vaccination age, and higher educational background of family showed younger vaccination ages. 4. With regard to positive rate of HBV markers by vaccination age, HBsAg and Anti-HBc positive rate showed higher degrees in the following order; preschool age (1-6 years), school age (6-13 years) and infancy (0-1 year). Anti-HBs positive rate was increased as the frequency of vaccination increased. Five years after initial complete vaccination, minimum protective rate was lowest, 69.6%.

• Journal of the Korean Society of School Health
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• v.5 no.1
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• pp.20-23
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• 1992

충치등의 구강질병은 예방이 가능하며 일단 발생하면 자연치유란 없고 질병의 진행만 있는 질병으로서 조기발견과 조기치료가 필요하다. 특히 학교연령층에서 폭발적으로 발생되고 있 기 때문에 학교구강보건관리가 중요하지만 선진국처럼 학교구강건강 관리실을 운영하고 전문인력을 상주 배치할 수 없는 현시점에서 예방교육과 조기발견, 조기치료를 위한 정기구강검사 제도는 필수적이다. 현행학교정기구강검사는 결핵, 간염, AIDS 등 질병의 전염문제와 검진비가 현실적이지 못하며 치과의사의 봉사강요형태로 진행되고 있는 문제 등이 있다. 그러므로 래원검진제 같은 의견도 있으나 현행 정기구강검진제를 개선하여 실시하는 것이 현실적이라고 본다. 기수소독문제는 치과의사 1인당 50개 정도의 기구가 준비되고 화학소독제로서 Glutal-dehyde(와이멕스)사용으로 해결될 수 있으며 기타 문제는 검진수가의 현실적 인상과 연계되어 근본적으로 해결될 수 있다.

• Food preservation and processing industry
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• v.16 no.2
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• pp.10-23
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• 2017

최근 햄버거 병을 시작으로 살충제 계란파동, E형간염 소시지까지, 급증한 식품안전 사고는 국민식품소비를 위축시키고 막연한 공포감 조성으로 올바른 식품섭취를 유지할 수 없도록 한다. 국민소득 증가와 더불어 식품의 안전성에 대한 소비자의 관심이 높아지고 있으며, 소비자는 보다 안전한 먹거리를 공급해줄 것을 요구하고 있다. 이에 대한 대응책을 마련하고자 정부와 식품업계, 학계 등은 고심하고 있다. 본 연구는 4차산업혁명에 발맞추어 식품안전분야에 ICT기술을 활용한 생산에서 소비자까지의 식품공급망의 안전관리를 체계화하는 FSMS(Food Safety Management System)을 구성해보고 그를 통한 식품의 안전도를 시험분석을 통해 효과를 검증하는 것이 목적이다. 본 연구는 FSMS의 기술요소인 빅데이터, 온습도IoT센서 등을 Pilot Test하고 FSMS 도입전과 도입후의 검체를 체품하여 공인식품시험검사기관에서 검체의 미생물수 분석을 통해 최종적으로 FSMS의 도입효과와 모형도를 제시하였다.

• Clinical and Experimental Pediatrics
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• v.52 no.11
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• pp.1279-1282
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• 2009

Hepatomegaly and liver dysfunction might develop in patients with diabetes mellitus due to glycogen deposition or nonalcoholic steatohepatitis. We experienced a case of hepatic glycogenosis in a patient with type 1 diabetes mellitus who presented with recurrent hypoglycemia, suggesting impairment of glycogenolysis and gluconeogenesis. A 10-year-old girl with a 4-year history of type 1 diabetes mellitus was admitted because of recurrent hypoglycemia and abdominal pain in the right upper quadrant. She had Cushingoid features and hepatomegaly that extended 6 cm below the right costal margin. Laboratory data and radiologic examination revealed elevated liver enzyme levels due to fatty liver. Periodic acid-Schiff (PAS) staining revealed intense glycogen deposition in the cytoplasm of the hepatocytes and PAS reactivity was lost with diastase treatment. At 2 months after administration of glucagon injection and uncooked cornstarch between meals and at bedtime, the hypoglycemic episodes and liver dysfunction improved. It is important to distinguish hepatic glycogenosis from steatohepatitis, because it is possible to prevent excessive hepatic glycogen storage in hepatic glycogenosis cases by strictly controlling blood glucose level and by glucagon administration. To prevent severe hypoglycemic symptoms accompanied by hepatic glycogenosis, we suggest that uncooked cornstarch, which is effective in maintaining blood glucose level, can also be administered.

• Pediatric Infection and Vaccine
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• v.16 no.2
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• pp.191-198
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• 2009

Purpose : Breastfeeding should be recommended for infants born to mothers with chronic hepatitis B Infection after postexposure prophylaxis. However, high proportion of these mothers are reluctant to engage in breastfeeding in Korea. This survey was taken to identify the cause of that reluctance. Method : Questionnaires were given to mothers with chronic hepatitis B infection who were registered at the 'Hepatitis B Perinatal Transmission Prevention Program' operated by Korea Center for Disease Control and Prevention. They visited a community health center for blood sample collection and signed a consent paper. The questionnaires were sent to the mothers. Result : Among 839 mailed questionnaires, 114 were returned marked 'address unknown'. The overall reply rate was 17% (n=125). Among responders, 52% (n=62) were breastfeeding and 48% (n=60) were formula-feeding. The most influential factor for breastfeeding was the mother's own decision (75%) and the obstetrician's recommendation (17%). For formulafeeding mothers, their decisions were influenced by obstetricians (57%), and by their own thinking (28%). The relationship between breastfeeding and perinatal prophylaxis failure was recognized as 45% 'related' and 50% 'not-related'. A total of 91% of breastfeeding mothers replied that they will breast-feed again. Among formula-feeding mothers, 78% answered that they will breast-feed if they were known that 'there is no direct relationship between breastfeeding and perinatal prophylaxis failure'. Conclusion : Despite the fact that there is no direct relationship between breastfeeding and perinatal prophylaxis failure, many were reluctant to breast-feed. Healthcare professionals have influence over the mothers for decision making. It will be necessary to educate healthcare personnel so that they can make a conceptual change as well as to promote the fact to the general public.

• Clinical and Experimental Pediatrics
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• v.50 no.9
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• pp.823-834
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• 2007

Interferon (IFN) alpha has been the first line therapy of chronic hepatitis B in children, but HBeAg seroconversion occurred in 26% of treated children compared to 11% of controls in multinational randomized controlled study. Recently, lamivudine was shown to be a potent inhibitor of Hepatitis B virus (HBV) reproduction both in HBeAg positive and in HBeAg negative (the pre-core mutant form) chronic hepatitis in randomized studies worldwide. Lamivudine therapy led to considerable improvement in the seroconversion rate of HBeAg in children with chronic hepatitis B, though long-term therapy resulted in the expansion of lamivudine-resistant mutant viruses. Combination therapy with lamivudine plus alpha-IFN does not seem to improve HBe Ag seroconversion. Above all, the most effective way to prevent hepatitis B is universal HBV vaccination.

• The Journal of Korean Society for School & Community Health Education
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• v.13 no.1
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• pp.45-53
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• 2012

Purpose: The purpose of this study was to identify relationship between knowledge and infection control behavior about Hepatitis B patient in health care-related majors. Methods: Data was collected from health care related majors-nursing, emergency rescue and dental hygiene with questionaire. Total respondents were 306 and we use all of them. We analysed students' knowledge and infection control behavior about Hepatitis B patient and their relationship. Uni-variate analysis, t-test, ANOVA and correlation analysis test were conducted using SAS version 9.2. Results: Students who go the Hepatitis B lecture were significantly high Knowledge level about Hepatitis B(p<.05). Students who go to clinical education about Hepatitis B were significantly better behavior about infection control in clinical practice(p<.05). The relationship between knowledge about Hepatitis B and infection control in clinical practice was significantly negative(p<.05). Conclusions: It needs to be educated both infection control lectures and clinical practice to health care-related majors to prevent cross-infection between patients and health care providers.