• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.11 no.sup2
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• pp.50-58
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• 2008

Acute liver failure is a devastating disease in children. Most cases of acute liver failure in children are indeterminate; however, metabolic liver disease is one of the main causes in the pediatric age group. Though a major symptom of acute liver failure is hepatic encephalopathy, this is very difficult to diagnose, particularly in younger children. Liver transplantation has improved the chances of survival dramatically; however, it is not known which patients are ideal candidates for liver transplantation. Because patients may deteriorate rapidly, arranging care in a center with expertise will secure the best possible outcomes.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.11 no.2
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• pp.210-213
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• 2008

Hyperacute liver failure from mushroom intoxication in children is rare and has a low survival rate. We report a case of hyperacute liver failure from mushroom intoxication in a 29-month-old boy. The patient ingested a mushroom about three days prior to presentation. He was admitted to the hospital with vomiting, abdominal pain, seizures, and hematemesis. During the hospitalization the patient developed hepatic encephalopathy (stage IV-a), and a coagulopathy. He recovered fully with specific medication, Penicillin GK and N-acetylcysteine.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.9 no.1
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• pp.108-113
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• 2006

In case of Wilson's disease complicated with hemolytic anemia and fulminant hepatic failure; plasma exchange or liver transplantation should be considered. We report an 11 year-old male with fulminant Wilson's disease who developed hemolytic crisis. He was recovered by exchange transfusion after 6 times of plasma exchange.

• Journal of The Korean Society of Inherited Metabolic disease
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• v.12 no.2
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• pp.99-103
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• 2012

Tyrosinemia type I is an autosomal recessive inborn error of tyrosine metabolism that caused a mutation. Clinical symptoms include progressive liver damage with liver failure, coagulopathy, hypophosphataemic rickets, renal tubular dysfunction and a high risk of hepatocellular carcinoma. If left untreated, the affected infants may die from liver failure within the first year of life. PharmacoloIcal therapy with 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione (NTBC) has offered an effective therapeutic option in addition to dietary restriction of tyrosine and phenylalanine. As prognosis of tyrosinemia type I is improving with early diagnosis and early treatments, it meets the criteria for a condition that would benefit from newborn screening. We report a case of tyrosinemia type I diagnosed by newborn screening and successive biochemical analysis of plasma and urine, treated by dietary restriction and NTBC.

• Clinical and Experimental Pediatrics
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• v.50 no.9
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• pp.841-847
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• 2007

Acute liver failure (ALF) is a very rare but devastating illness in children. Specific treatment to recovery is often not available, and the underlying cause of the liver failure is often unknown and diverse especially in children. Liver transplantation has increased the chance of survival; however it needs an optimal timing to reach the best result which is not familiar to pediatrician. This article discusses the current knowledge of the epidemiology, backgrounds and factors to be considered before establishing the treatment of ALF in children.

• Tuberculosis and Respiratory Diseases
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• v.63 no.5
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• pp.435-439
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• 2007

Standard antituberculous therapy, including isoniazid (INH), rifampin, ethambutol, and pyrazinamide (PZA), is widely used to treat active tuberculosis. The most important side effect is hepatotoxicity. In a standard four-drug regimen, PZA was the most common cause of drug-induced hepatitis and was dose-related. The incidence of drug-induced hepatitis is high at doses of 40~70 mg/kg per day but has fallen significantly since the recommended dose was reduced. Liver toxicity induced by PZA is rare at doses of 25 mg/kg per day or less. PZA-induced fulminant hepatic failure is also rare but fatal. We report a case of fulminant hepatic failure caused by a re-challenge of PZA.

• Journal of Chest Surgery
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• v.35 no.2
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• pp.87-93
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• 2002

Background: Predicting the important role of intercellular adhesion molecule-1 expression on the acute ischemia-reperfusion injury, we set out to demonstrate it by assessing the degree of expression of ICAM-1 after warm ischemia-reperfusion in canine unilateral lung ischemia model. Material and Method: Left unilateral lung ischemia was induced by clamping the left hilum for 100 minutes in seven adult mongrel dogs. After reperfusion, various hemodynamic pararmeters and blood gases were analyzed for 4 hours, while intermittently clamping the right hilum in order to allow observation of the injured Ieft lung function. The pulmonary venous blood was collected serially to measure TNF- and cICAM-1 level. After 4 hours of reperfusion, the lung tissue was biopsied to assess cICAM-1 expression, and to measure tissue malondialdehyde(MDA) and ATP level. Result: The parameters including arterial oxygen partial pressure, pulmonary vascular resistance and tissue MDA and ATP level suggested severe lung damage. Serum TNF-$\alpha$ level was 8.76$\pm$2.37 ng/ml at 60 minutes after reperfusion and decreased thereafter. The cICAM-1 level showed no change after the reperfusion during the experiment. The tissue cICAM-1 expression was confirmed in 5 dogs. Conclusion: The increase of TNF-$\alpha$ Ievel and expression of tissue ICAM-1 were demonstrated after ischemia reperfusion injury in canine lung model.

• The Journal of the Korea Contents Association
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• v.16 no.7
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• pp.730-739
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• 2016

The purpose of this study is to find improvements in current issues faced in counseling training within the military and also show limits in counseling capabilities of military officers who are in charge of leading and counseling their troops. In reference to previous studies made on this topic, we looked at issues rising from military troops who are mainly in their post-adolescents having difficulties in adopting themselves to military life style. We also studied current status of counseling within the military and the counseling difficulties faced by military officers who are closely related to their troops.Survey and in-depth interviews were conducted to achieve the purpose of this study. 100 military officers were surveyed for the frequency of the counseling sessions, and to supplement the survey, in-depth interviews were conducted 3 military officers and analyzed qualitatively. As a result of the survey and the in-depth interviews 76.5% of the military officers never had counseling training prior to joining the military and only 32.9% received counseling training after joining the military. 61% of the survey participants expressed difficulties in counseling their troops. Most of them expressed difficulties in lack of training and issues on theory based training. For the improvements following have been identified; "understanding the troops", "Identifying the problems", "Execution of the training" and "Techniques for Military Training". This study has a meaning in terms of identifying improvement areas in counseling training in the military through researching into current limits in military counseling and military officers counseling capabilities when the social issue of new troops having difficulties in adopting to military life style are on the rise.

• Defense and Technology
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• no.10 s.236
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• pp.22-33
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• 1998

21세기를 대비하는 지상군은 미래의 전장운영개념을 다양한 위협에 대처할 수 있도록 재정립하여야 한다. 또한 이 기본개념을 바탕으로 현존전력 극대화하고 미래전력을 창출하기 위해 방위력 개선 방향을 설정하여야 한다. 특히 "I.S.R (정보.감시.정찰)+$C^4I$+PGM(정밀유도무기)" 체계의 통합하에 정보전, 정밀타격전, 입체고속전 등을 수행할 수 있도록 하며 간부계발과 교리, 훈련, 군구조 및 편성, 무기.장비, 자원관리의 제 요소를 총합체계적으로 발전시켜 나가야 한다.

• Survey Research
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• v.7 no.1
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• pp.29-53
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• 2006

This paper analyzes which of the military sub-fields has an effect on a soldier's evaluation of South and North Korean military power. There are three objectives of this paper. First, it is to analyze whether the South is superior to the North in the overall military power and military sub -fields, without the presence of the US armed forces in South Korea. Second, it is to assess which of the military sub-fields influences the overall evaluation of military power through a regression analysis. Finally, it is to look at whether the professional soldiers have a motivational bias, due to an argument that the military personnel tend to exaggerate the inferiority of their own military power to get more budget for defense construction. Research in 2002 and 2003 tell us that South Korean military power is slightly inferior to North Korea's. However, research in 2005 shows that military power of South and North Korea is almost equal. The sub-fields in which South Korea is superior are in the order of War Sustainability, Information Warfare, Air Force, and Navy. North Korea is regarded to be superior in the fields of Atomic Biological Chemical Warfare Capability, Special Force, Reserve Mobilization, and Army. The higher ranked soldiers tend to evaluate that the North is superior to the South.