• Journal of Pharmacopuncture
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• v.10 no.1 s.22
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• pp.137-155
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• 2007

Purpose : This study was undertaken to make a diagnosis weakness and firmness (虛實) of Dysmenorrhea patients by diagnosis questionnaires system(Diagnosis System of Oriental Medicine-DSOM) Methods : The subjects were 58 volunteers who was suffering for dysmenorrhea, employed using Measure of Menstrual Pain (MMP) questionnaire. The had agreed to take part in this experiment, with didn't take any anodyne drugs. The MMP score by using 7 questions and the Menstrual Symptom Severity List(MSSL-D) was measured before and after menstruation cycle. Results and Conclusions : The findings of this study were as follows; 1. We examined Pathogenic Factor's frequency of DSOM, Coldness(寒) was 45 persons 80.36%, Damp(濕) was 40 persons 71.43%, Heart(心) was 37 persons 66.07%, Heat syndrom(熱) was 9 persons 16.07%, insufficiency of Yang(陽虛) was 6 persons 10.71%. 2. We divided Dysmenorrhea patients into two groups(weakness and firmness) by Results of DSOM, Firmness was 25 Persons 43.1%, Weakness was 23 persons 39.7%, Unknown was 10 persons 17.2%. 3. In estimation based on Measure of Menstrual Pain (MMP) questionnaire Severe menstrual pain is weakness, Mild menstrual pain is Firmness. 4. In estimation of coldness and heat syndrom, Coldness was 40 persons 69.0%, Heat syndrom, was 2 persons 3.5%, Possess both coldness and heat syndrom was 9 persons 15.5%.

• The Journal of the Korea Contents Association
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• v.18 no.8
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• pp.345-352
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• 2018

The purpose of this study is to clarify the difference between the scoring results by scorer(doctors and standardization patients) and examination dates. A total of 101 students in the fourth grade of medical school participated in four clinical practice test. Students were randomly assigned to either day-1 or day-2, which was consisted of a standardized patient scoring set or a physician scoring set. Station checklists consisted of history taking, physical examination, patient education, physician-patient relationship and clinical courtesy. The achievement scores of each case and each domain were converted to the standard score, and the differences between groups were compared. Female students' achievement scores were significantly higher than male students' achievement scores in all domains. There was no significant difference between means by the standardized patients' group and doctors group. Day-2 group was significantly higher than day-1 group in both of history taking and physical examination domains. If the principles of checklist are clearly defined, the scorer status (either physician or standardized patients) does not determine the difference of students' practice test scores.

• Clinical and Experimental Reproductive Medicine
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• v.9 no.1_2
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• pp.43-53
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• 1982

여성의 난소기능은 뇨중 Oestrone-3-glucuronide를 간편한 solid-phase 의 화학발광성 면역학적 측정법 (Chemiluminescence Imrnunoassay(CIA) 에 의하여 그 기능이 탐지될 수 있다. Oestrone-3-g1ucuronyl-6-bovine serum albumine에 대한 antiserum의 IgG fraction은 polystyrene 실험관벽에 흡착시켰으며, 항원으로서는 est r one-3- gl ucuronyI-6-aminoethyl-ethyl-isoluminol 을 항원 (antigen) 에 labeI 시킨 것이다. 시험 대상물인 뇨는 매일아침뇨(early morning urine) 을 희석 (1:1000 V/V)한 후 100mcl 를 취하여 이를 각기 이중분석액으로 택하였다. 시험관 내에서 결합반응 (1 hour at $4^{\circ}C)이 일어난 후에는 시험관내의 액체를 전부 흡입 폐기시켰으며, 항체반응이 일어난 후 ( antibody-bound fraction )에는 완충액 (400mcl)으로 한번 세척시켰다. 그후 염화수산화물(2N , 200mcl)을 가지고 $22^{\circ}C$에 60 분간 방치 혼합케 한 후 효소(microperoxidase) 와 과산화수소를 가하면서 산화작용에서 발생되는 발광양을 10초동안 측정하여 그 결과를 분석하였다. 위에 기술한 분석방법을 평가하면 다음과 같은 결론을 얻었다. Calibration curve sensitivity$3.12{\pm}0.75$ PG/tube ($mean{\pm}SD$)였고, lntra-assay precision(CV%) 9.52 (20 replicates;$38.4{\pm}3.66$nmol/1) 와 8.81 (15 replicates; $102.4{\pm}8.82$nmol/1)였다. Inter-assay precision(CV%) 은 11.9 (mean of 4 pools-7.03, 23.16, 52.11 과 117.53 nmol/1)로 2개월 동안에 걸쳐 시행되었고, 평균 비이어스(mean bias)는 -0.78 로 28에서 448 nmol 범위로서 매일아침 "뇨"의 차이분(different aliquots)은 좋은 결과를 얻었다. 건강한 여성으로부터 채취된 뇨중 Oestrone-3-glucuronide 의 농도(nmol/1)를 보면 월경주기의 여포기와 배난기 및 황체기에 있어서 각기 $40.2{\pm}9.9$ , $102.3{\pm}39.4$와 $84.3{\pm}13.3$nmol/1였다. 이와같은 결과는 동일한 검사뇨를 방사면역학적 방법(RIA)으로 측정 (6 menstrual cycle)한 결과와 유사한 측정치를 얻으므로서 간편하고 진보된 좋은 방법중의 하나라고 사료되는바이다.

• Korean Journal of Psychosomatic Medicine
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• v.7 no.2
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• pp.247-251
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• 1999

Background : Iron deficiency anemia(IDA) is a very common condition, and its underlying causes are diverse. Gastrointestinal blood loss, pregnancy, menorrhagia are known as common causes of IDA. However, especially in the IDA case of unknown origin, we must consider the culture specific cause of IDA as a possible cause of IDA. As I found an unusual cause of IDA related to a cultural behavior, I would like to report two cases of IDA occurred by negative therapy in Korea. It is possible to explain these cases by explanatory model. Case 1 : With a chief complaint of dyspnea, a 27-year-old woman visited our clinic. She had multiple treatment histories of negative therapy for her psoriasis. The blood loss during this procedure is the cause of present IDA. Case 2 : A 70-year-old man visited our clinic complaining of anorexia and dizziness. The history of treatment showed that he had an IDA 9 month ago. The IDA developed again because of repeated negative therapy after previous treatment of IDA. He has used the negative therapy intermittently to treat tinea pedis for 5 years. Conclusion : We must consider the negative therapy as a possible cause of IDA in Korea.

• Environmental and Resource Economics Review
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• v.26 no.1
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• pp.57-83
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• 2017

The Japanese government's attempts to reduce fine particles (PM2.5) emission pollution in Japan have been largely ineffective. This is because PM2.5 in Japan originated from various sources including around half from oversea countries such as China. This prompts the Japanese government to start a new initiative to reduce PM2.5 at its origin by transferring local knowledge on air pollution reduction measures and technologies to China and working closely with the Chinese government. To promote further reduction in PM2.5, bilateral corporation between Japan and China should be extended to include Korea. It is recommended that an international convention should be in place to deal with transboundary air pollutants in East Asia. A successful East Asia corporation to reduce PM2.5 will not only contribute to clean air but also to future sustainable low carbon society in this region.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.10
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• pp.4943-4952
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• 2013

This study was conducted among Korean women over aged 60 who participated in Korea National Health and Nutrition Examination Survey (KNHANES) (the 2nd and 3rd year at the 4th survey, and the 1st year at the 5th survey). The purpose of the study was to figure out a relation between femoral neck and lumbar spine bone mineral density and anthropometry, life style, diet, fracture history, family history of osteoporosis, medical history, menstrual history and reproductive factor. To express the strength of the associations, percent differences were calculated from multiple linear regression models using the formula ${\beta}{\times}$(unit/mean BMD). Unit for continuous variables were chosen to approximate 1 standard deviation(SD). In women aged 60 or older, lean mass(B: 0.257) and fat mass(B: 0.237) greatly influenced bone density in the femoral neck and lumbar spine. Therefore it will be an effective way to prevent osteoporosis for elderly women by increasing lean mass and maintaining proper weight.

• The Journal of Korean Obstetrics and Gynecology
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• v.19 no.3
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• pp.231-245
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• 2006

Purpose : To investigate and compare the characteristics of menstruation in the shift workers and the day workers, and present guidelines for health promotion of the shift-working women. Methods : Questionnaires including general health condition and QSCC II were distributed to shift-working women and day-working women in one university hospital in Gyeonggi-do and 36 questionnaires of shift-working women and 33 of day-working women were analyzed. Results : Day workers were about 5 years older than shift workers on average. There was more irregularity of menstrual cycle and period in day-working group but it is thought to incorrect because of the age problem. There were more women who have dysmenorrhea in day-working group, but the proportion of dysmenorrhea which continues more than 72 hours -which is very suggestive of secondary dysmenorrhea- was higher in shift-working group. Average VAS of dysmenorrhea was nearly the same in two groups. The life of shift-working group was lesser satisfactory than that of day-working group. There were more sleep disturbances in the shift-working group. Sasang constitution was analyzed in both group using QSCC II, and Taeumin were more in shift-working group. Conclusion : As the number of shift-working women increases, needs for oriental medical treatments would increase because it is more natural and lesser invasive managements which women are very interested in. So it is thought to be necessary to understand health problems of shift-working women, and prepare guidelines for managements and treatments to promote the health of shift-working women.

• The Journal of Korean Obstetrics and Gynecology
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• v.24 no.3
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• pp.98-108
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• 2011

Objectives: The purpose of this study is to investigate the relationship between granulocyte/lymphocyte ratio and dysmenorrhea, history of gynecological disease, heart rate varibility(HRV). Methods: From May 1st 2011 to July 10th 2011, a total of 40 female subjects (age 20-39) were recruited. We evaluated the menstruation condition by questionnaires including VAS(Visual Analog Scale), VRS(Verbal Rating Scale) and MVRS (Multidimensional Verbal Rating Scale), also measured subject's WBC differential count and HRV. Results: 1. There was no statistically significant difference in granulocyte/lymphocyte ratio according to menstruation cycle, duration, amount, color, and blood clot. 2. There was no statistically significant difference in VAS, VRS, MVRS mean scores between normal group and abnormal group according to granulocyte/ lymphocyte ratio. 3. The past prevalence of gynecological disease of abnormal group showed significantly higher compared with that of normal group($x^2$=6.578, p=0.010). 4. LF/HF ratio and granulocyte ratio significantly showed positive correlation ($r_s$=0.311 p=0.048) and LF/HF ratio and lymphocyte ratio significantly showed negative correlation($r_s$=-0.319 p=0.045). Conclusion: These findings suggest that the gynecologic diseases are related to disorder of autonomic nervous system, but not dysmenorrhea. And the balance state of sympathetic/parasympathetic nerve infered through granulocyte/lymphocyte ratio and HRV seems to be consistent. However, reconfirmation through further studies is needed.

• The Journal of Korean Obstetrics and Gynecology
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• v.20 no.2
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• pp.188-195
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• 2007

Purpose: The purpose of this study was to analyze current status of the web-sites dealing with oriental obstetrics & gynecology in the internet, and to evaluate their quality and confidence of health information. Methods: It was selected 54 local sites by searching for such key words as menstrual pain. The evaluation tool consisted of six major classification (Content, Authorship, Purpose, Functionality, Feedback and Privacy). Results: In the evaluation of web-sites, the lowest and the highest scores were 7 and 19 out of 26, and the average score was 13.94. The scores of Purpose, Content, Feedback were higher than the average, but the scores of Authorship, Functionality, Privacy were lower than the average. Conclusion: There is a need to develop a high-quality information about latest, confidence, authorship of documents, and to prevent a exposure of privacy.

• The Journal of Korean Obstetrics and Gynecology
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• v.20 no.2
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• pp.176-187
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• 2007

Purpose: Recent studies show that Skin Resistance Variability(SRV) could be related to the functions of Hypothalamus-Pituitary-Ovary(H-P-O) axis. 7-Zone-Diagnostic System is oriental medicine measuring system using SRV. To know the differences of SRV of normal and abnormal menstrual cycle groups, we research the SRV of the two groups. Methods: We measured SRV of two groups that were consist of 126 women who took CP-6000A test in Sangji Oriental Medical Hospital from Mar. 2004 to Feb. 2006. After detection of SRV, we performed correlation analysis by SPSS 12.0. Results: The SRV was measured twice in 7 areas. By the results of 1st trial on Factor AA of the SRV, the patient group's results were lower than normal group's results in all 7 areas. And there were remarkable differences in 1, 2, 3, 4, 5, 7 areas between two groups. By the results of 2nd trial on Factor AA of the SRV, the patient group's results were lower than normal group's results in all 7 areas similar to 1st trial results. And there were remarkable differences in 2, 3 areas between two groups. Conclusion: Comparing normal group with patient group, these results may reflect the relations of abnormal menstrual cycle and H-P-O axis functions. Because patient's results were lower than normal's in all 7 areas. And remarkable different results in 2, 3 areas were repeated by twice trial all. Further study will be needed.