• Tunnel and Underground Space
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• v.32 no.6
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• pp.558-567
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• 2022

The evolution of temperature and thermal stress in a granite specimen is studied via heating experiment in the context of a high-level radioactive waste repository. A heating condition based on the decay-induced heat is applied to a cubic granite specimen to measure the temperature and stress distributions and their evolution over time. The temperature increases quickly due to heat conduction along the heated surfaces, but a significant amount of thermal energy is also lost through other surfaces due to air convection and conduction into the loading machine. A three-dimensional finite element-based model is used to numerically reproduce the experiment, and the thermo-mechanical coupling behavior and modeling conditions are validated with the comparison to the experimental results. The most crucial factors influencing the heating experiment are analyzed and summarized in this paper for future works.

• Journal of the Korea Society of Computer and Information
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• v.14 no.2
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• pp.211-219
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• 2009

The logistic environment of Korean companies faces very challenging circumstances due to lack of resources and tough price competitions. It is obvious that such a load of logistic cost becomes an obstacle to national or business competition advantages in the era of unlimited market competition. Prior studies concerning these issues sought to express a large-scale distribution network in a unified numerical formula using defined symbols and could take systematic approaches to distribution network. But inventory policy and operation in material distribution system have been limited to conventional methodology. so they are exposed to many questions in practical applications. This study analyzed distribution system cost and developed a relevant model for operation policy of distribution system for the efficeient treating of stockout. allowing practical applications, so that it will contribute to saving operational cost related to material distribution system.

• Tuberculosis and Respiratory Diseases
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• v.86 no.3
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• pp.234-244
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• 2023

Background: Effective treatment of fluoroquinolone-resistant multidrug-resistant tuberculosis (FQr-MDR-TB) is difficult because of the limited number of available core anti-TB drugs and high rates of resistance to anti-TB drugs other than FQs. However, few studies have examined anti-TB drugs that are effective in treating patients with FQr-MDR-TB in a real-world setting. Methods: The impact of anti-TB drug use on treatment outcomes in patients with pulmonary FQr-MDR-TB was retrospectively evaluated using a nationwide integrated TB database (Korean Tuberculosis and Post-Tuberculosis). Data from 2011 to 2017 were included. Results: The study population consisted of 1,082 patients with FQr-MDR-TB. The overall treatment outcomes were as follows: treatment success (69.7%), death (13.7%), lost to follow-up or not evaluated (12.8%), and treatment failure (3.9%). On a propensity-score-matched multivariate logistic regression analysis, the use of bedaquiline (BDQ), linezolid (LZD), levofloxacin (LFX), cycloserine (CS), ethambutol (EMB), pyrazinamide, kanamycin (KM), prothionamide (PTO), and para-aminosalicylic acid against susceptible strains increased the treatment success rate (vs. unfavorable outcomes). The use of LFX, CS, EMB, and PTO against susceptible strains decreased the mortality (vs. treatment success). Conclusion: A therapeutic regimen guided by drug-susceptibility testing can improve the treatment of patients with pulmonary FQr-MDR-TB. In addition to core anti-TB drugs, such as BDQ and LZD, treatment of susceptible strains with later-generation FQs and KM may be beneficial for FQr-MDR-TB patients with limited treatment options.

• Korean Journal of Environmental Agriculture
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• v.28 no.3
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• pp.233-237
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• 2009

It has widely been observed that the effect of elevating atmospheric $CO_2$ concentrations on rice productivity depends largely on soil N availabilities. However, the responses of ammonia volatilization from flooded paddy soil that is an important pathway of N loss and thus affecting fertilizer N availability to concomitant increases in atmospheric $CO_2$ and temperature has rarely been studied. In this paper, we first report the interactive effect of elevated $CO_2$ and temperature on ammonia volatilization from rice paddy soils applied with urea. Urea labeled with $^{15}N$ was used to quantitatively estimate the contribution of applied urea-N to total ammonia volatilization. This study was conducted using Temperature Gradient Chambers (TGCs) with two $CO_2$ levels [ambient $CO_2$ (AC), 383 ppmv and elevated $CO_2$ (EC), 645 ppmv] as whole-plot treatment (main treatment) and two temperature levels [ambient temperature (AT), $25.7^{\circ}C$ and elevated temperature (ET), $27.8^{\circ}C$] as split-plot treatments (sub-treatment) with triplicates. Elevated temperature increased ammonia volatilization probably due to a shift of chemical equilibrium toward $NH_3$ production via enhanced hydrolysis of urea to $NH_3$ of which rate is dependent on temperature. Meanwhile, elevated $CO_2$ decreased ammonia volatilization and that could be attributed to increased rhizosphere biomass that assimilates $NH_4^+$ otherwise being lost via volatilization. Such opposite effects of elevated temperature and $CO_2$ resulted in the accumulated amount of ammonia volatilization in the order of ACET>ACAT>ECET>ECAT. The pattern of ammonia volatilization from applied urea-$^{15}N$ as affected by treatments was very similar to that of total ammonia volatilization. Our results suggest that elevated $CO_2$ has the potential to decrease ammonia volatilization from paddy soils applied with urea, but the effect could partially be offset when air temperature rises concomitantly.

• Fire Science and Engineering
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• v.25 no.2
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• pp.101-106
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• 2011

In case of an emergency such as a fire on a building and there is a need to evacuate the occupant in that building, it is important to have the guidance information effectively delivered to the evacuating occupants to guide them toward a safe direction using audio sensual media. And, it is also very important to prevent the evacuating occupants getting lost or falling astray, away from the direction toward safety. The purpose of this study, in this respect, is to examine the possible application of the precedent sound effect, with which the evacuating occupants may get a sense of the direction where the announcement comes from. With such an effect, an experiment was conducted to measure the extent to which people can hear the preceding and the following sound in terms of the acoustic pressure level changes and delay time changes, with a view to make the optimal evacuation-guidance announcement or sound. The optimal evacuation guidance sound (announcement) per each of the experimental indoors environments were as follows; 1) Regarding the optimal condition for the evacuation guidance announcement sound in the space of a lecture room, the direction of the advanced sound is positively recognized when the follow-up sound has the delaying time of 10 ms~50 ms in comparison with the advanced sound or when there is no difference between the acoustic pressures of the advanced and follow-up sounds or the acoustic pressure of the advanced sound is higher than that of the follow-up sound. 2) Regarding the optimal evacuation guidance announcement sound in the space of a hall, the advanced sound is positively recognized when the follow-up sound has the delaying time of 20 ms~60 ms in comparison with the advanced sound. 3) Regarding the optimal evacuation guidance announcement sound in the space of a gymnasium, the advanced sound is positively recognized when the follow-up sound has the delaying time of 10 ms~40 ms in comparison with the advanced sound or when the sound pressure of the advanced sound has a higher level than or the same level as that of the follow-up sound.

• Korean Journal of Microbiology
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• v.47 no.1
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• pp.92-96
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• 2011

Rhodococcus sp. strain DK17 possesses three megaplasmids (380 kb pDK1, 330 kb pDK2, and 750 kb pDK3). The alkylbenzene-degrading genes (akbABCDEF) are present on pDK2 while the phthalate operons which are duplicated are present on both pDK2 (ophA'B'C'R') and pDK3 (ophABCR). DK17 with an optimal temperature of $30^{\circ}C$ showed no growth at $37^{\circ}C$. When transferred to $30^{\circ}C$, however, the $37^{\circ}C$ culture began to grow immediately, indicating that $37^{\circ}C$ is not lethal but stressful for DK17 growth. In addition, when exposed to $37^{\circ}C$ even for a short time, a part of DK17 cells lost the ability to degrade o-xylene (a model compound of alkylbenzenes). When two hundred colonies were randomly selected for colony PCR for pDK2-specific akbC, ophC', or pDK3-specific ophC, a total of 29 colonies were found to have lost at least one of the three genes. PFGE analysis clearly showed that all the mutants have different megaplasmid profiles from that of DK17 wild type, which are divided into five different cases: Type I (10 mutants, pDK2 loss and acquisition of a new ~700 kb plasmid), Type II (9 mutants, pDK2 loss), Type III (8 mutants, pDK3 loss and acquisition of a new ~400 kb plasmid), Type IV (1 mutant, pDK3 loss), and Type V (1 mutant, pDK2 and pDK3 loss and acquisition of the ~400 kb and ~700 kb plasmids). The above results showing that growth temperature changes can induce physical changes in bacterial genomes suggest that environmental changes in habitats including temperature fluctuations affect significantly the evolution of bacteria.

• Korean Journal of Soil Science and Fertilizer
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• v.41 no.5
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• pp.354-361
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• 2008

In this study, we analyzed nutrient cycling structure of a small farm (cattle of 100 heads and arable lands of 2.5 ha) in Jeonnam province to investigate the effects of nutrients input by the addition of bedding materials (sawdust and rice hull) and nutrients loss before the application to the soils (the period during manure storage in the feedlot and composting process) on nutrient cycling structure. Sawdust and rice hull added as bedding materials increased N by 1.6% and 14.2% and $P_2O_5$ by 3.1% and 27.4%, respectively, relative to the amount of nutrients produced by excretion. This result suggests that the addition of nutrients via bedding materials should be considered for better estimation of nutrient balance. The most significant characteristics of the nutrient cycling structure was loss of mass and nutrients during the storage (21 days) and composting period (90 days). During this period, 78.4% of N and 9.5% of $P_2O_5$ was lost from sawdust compost; meanwhile, the percentages of loss for rice hull compost were 81.6% and 10.3%, respectively. A lower percentage of nutrients loss in sawdust compost than that in rice hull compost was attributed to the relatively slow decomposition rate of organic materials in the sawdust compost which has higher C/N ratio and lignin contents. Therefore, it was concluded that estimation of nutrient balance should be conducted based on nutrient contents in the final compost being applied to the lands rather than the amount of nutrients contained in the livestock excretion. In addition, the effects of bedding materials on nutrient losses should be also taken into account.

• Development and Reproduction
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• v.10 no.4
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• pp.263-269
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• 2006

To evaluate the potentiality of industrial use of cysteine proteinase inhibitor (cystatin) of tilapia egg and serum stability of the tilapia cystatin on low temperature storage and heat treatment was studied. When the eggs were stored at $4^{\circ}C$ for 3 days the cystatin activity was not changed much, while the supernatant of egg homogenate lost its cystatin activity significantly, remaining only about 65% of initial activity. When the eggs and serum were subjected to repeated freeze at $-20^{\circ}C$ and thaw at room temperature once a day, the egg cystatin was decreased after 5 cycles of freeze and thaw. However the serum cystatin was not changed by the 5 times repetition of freeze and thaw. More than 80% of egg cystatin activity was remained when the egg was heated at $35^{\circ}C$ for 30 min, but less than 10% was remained when heated at $50^{\circ}C$. On the other hand, the serum cystatin was very resistant to heat, remaining about 74% after heating at as high as $80^{\circ}C$ for 30 min. In summary, the egg cystatin was more stable when stored as intact form of egg rather than as supernatant of homogenate when stored at refrigeration. Egg cystatin was relatively stable against repeated freeze-thaw, and serum was found to be more stable in cysteine proteinase inhibitory activity than egg. Egg cystatin was not very resistant to heat treatment, while serum cystatin was quite resistant to high temperature heat treatment. These results suggest that tilapia egg and serum, especially the serum, would be a useful source for cysteine proteinase inhibitor in surimi production.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.48 no.6
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• pp.401-410
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• 2020

In this study, a real-time Tactical UAS position compensation system based on image information developed to compensate for the weakness of location navigation information during GPS signal interference and jamming / spoofing attack is described. The Tactical UAS (KUS-FT) is capable of automatic flight by switching the mode from GPS/INS integrated navigation to DR/AHRS when GPS signal is lost. However, in the case of location navigation, errors accumulate over time due to dead reckoning (DR) using airspeed and azimuth which causes problems such as UAS positioning and data link antenna tracking. To minimize the accumulation of position error, based on the target data of specific region through image sensor, we developed a system that calculates the position using the UAS attitude, EO/IR (Electric Optic/Infra-Red) azimuth and elevation and numerical map data and corrects the calculated position in real-time. In addition, function and performance of the image information based real-time UAS position compensation system has been verified by ground test using GPS simulator and flight test in DR mode.

• Korean Journal of Soil Science and Fertilizer
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• v.45 no.6
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• pp.1094-1099
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• 2012

Green manure cultivation affects soil productivity and nutrient conservation in paddy soil at winter season. This study was to evaluate nitrogen behavior released from chinese milk vetch (CMV) as green manure by using stable $^{15}N$ trace during rice cultivation. The CMV used in the experiment was 29.9 of C/N ratio and 14.1 g N $kg^{-1}$ ($^{15}N$ 0.388 atom % excess) and was applied at rates of 10 and $30Mg\;ha^{-1}$ in pot of 1/2000a size. Rice growth and N uptake increased with higher levels of CMV application at harvesting stage. Among total N uptake, 14.6 and 26.8 % of nitrogen was released respectively from the two different rates of CMV application. Stable $^{15}N$ recovery by rice biomass was 60%, 54% to the $^{15}N$ input, respectively, of CMV application, which decreased in order of grain, root, and straw of rice biomass. Total N content in the soil after rice harvest was 1.9 and 2.1 g N $kg^{-1}$, respectively, with increasing N input by the different rates of CMV application and the rate of $^{15}N$ recovery derived from CMV in the soil was 3.8 and 4.8 %, respectively. N input by CMV application induced rice growth and productivity during rice cultivation. However, it might need proper managements to reduce N loss because about 36-41 % of nitrogen was lost from N input by CMV application.