• Journal of Nutrition and Health
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• v.36 no.5
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• pp.476-482
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• 2003

We studied the effects of soy isoflavone supplements on bone metabolism marker (serum osteocalcin, urinary deoxypyridinoline) and urinary mineral excretion (urinary Ca, Mg, Zn) in 47 postmenopausal women. There were 24 participants in the treatment group and 23 in the control group. The treatment group consumed isoflavone extract capsules daily (which contained 90 mg of soy isoflavones) for 12 weeks. The study compared before and after isoflavone intake in the following areas: Physical examination, diet survey, bone metabolism marker and urinary mineral excretion. The average age of the treatment group was 64.6 years and that of the control group was 66.5 years. There were no significant differences between the two groups in terms of height, weight and body mass index. Both groups maintained a regular diet pattern in terms of their average daily nutrient intake. There were no significant differences between the treatment group (23.9 mg) and the control group (25.4 mg) in terms of daily isoflavone intake based on diet. The analysis of bone metabolism marker changes in the treatment group after 12 weeks of taking the isoflavone supplements demonstrated significant differences in the following: Serum osteocalcin (13.7 ng/mL in befor versus 6.8 ng/mL in after) and urinary deoxypyridinoline (5.9 nmol/mmol Cr in befor versus 4.5 nmol/mmol Cr in after). The subjects in the treatment group showed no significant difference in urinary Ca excretion. But the subjects showed a significant difference in urinary Mg (131.9 mg/day in befor versus 115.6 mg/day in after) and Zn (400.5 $\mu\textrm{g}$/day in befor versus 310.2 $\mu\textrm{g}$/day in after) excretion in the isoflavone treatment group at the levels of p<0.001, p<0.01, respectively. No changes were made in the intake of minerals. The composition of serum osteocalcin and urinary deoxypyridinoline, and indicators of bone metabolism, including the excretion Mg and Zn, significantly decreased. As a result, bone mineral loss was lessened. (Korean J Nutrition 36(5): 476~482, 2003)

• Journal of Nutrition and Health
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• v.14 no.4
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• pp.209-219
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• 1981

To evaluate long-term metabolic response of free-living Korean subjects consuming local sources adequately or slightly below habitual intake. Subjects, six male medical students aged 23-25 years were free-living, but consumed diets in the metabolic unit. They were healthy as determined from medical laborarory tests. They belong to the Korean middle-class. Temperature of outdoor during study were ranged between -2 to $26^{\circ}C$, whereas the indoor were $18-22^{\circ}C$. Animal protein ranged between 25-30% of total calorie. The three meals and a vitamin supplement to meet recommendation were given daily. Three 50day periods following the design were used to test the protein-energy adequacy of the diet. Urinary nitrogen excretion was measured daily. Fecal samples were pooled for the last 5 days of each week. Nitrogen balance was computed using 5mg N/Kg skin and miscellaneous losses. Body weight was measured daily. The study was covered on 126 metabolic observations weekly. Body weight changes were relatively stable with the energy intake of 37-44Kca1/kg, and N-balances were also relatively stable, but it was influenced by physical and or mental stress somehow. It could be assumed that the mean protein and energy requirement were $190{\pm}10mg$ N/Kg with $41{\pm}2$ Kcal/kg, and the mean digestibility of protein was 81% on these subjects with the experimental conditions. The protein requirement, however, could be cut down somewhat with some limited increaing of energy intake under parameters of N-balance and maintaining body weight. It was also observed a tendency of the requirement were getting smaller with the increase of body size.

• Journal of Nutrition and Health
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• v.45 no.1
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• pp.5-11
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• 2012

We investigated the effects of short-term food restriction and repeated fasting and refeeding on appetite regulating hormones and adiponectin activity in rats. To investigate the acute and chronic effects of food restriction in vivo, Sprague-Dawley rats were divided into a control group (CON), a 1 day fasting group, a 2 days fasting gruop, a 3 days fasting gruop, a fasting and refeeding for 1 week gruoup and a fasting and refeeding for 2 weeks group. Blood glucose, triglyceride and total cholesterol decreased in all fasting groups compared to those in the CON group. Free fatty acid of all fasting groups was higher than those in the CON, and were lowest in the three cycle fasting and refeeding group. Blood insulin following short-term food restriction was lower than that in the CON. blood ghrelin increased significantly (p < 0.01) following the short-term food restriction, However, blood ghrelin in the repeated fasting and refeeding groups decreased significantly decreased (p < 0.01) compared to that in the CON and short-term food restriction group. In contrast, blood leptin decreased significantly (p < 0.01) in the short term food restriction group and the three cycle of fasting and refeeding group but increased in the six cycle of fasting and refeeding group. No significant differences in adiponectin contents were observed in the short-term food restriction group. But, adiponectin increased significantly (p < 0.01) following the fasting and refeeding cycles. Blood adiponectin and blood leptin levels were showed positively correlated ($r^2$ = 0.469) when all samples were analysed together.

• KIEAE Journal
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• v.10 no.3
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• pp.43-50
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• 2010

Natural lighting is directly connected with our mental and physical health. For working or learning effect, the proper natural lighting is required for improving our living conditions. School facilities, especially, are the place where includes students' ordinary activities with learning behaviors during the school years from elementary to high school. This study was carried out for the purpose introducing a basic database in that planning a school by researching on the actual in the natural lighting system of some schools' classroom, estimating, and analyzing through a simulation, which resulted in a method of improving the natural lighting system. As a result of measuring and analyzing Daylight Factor(DF) during the time from 9 am to 3 pm when students are activating in their classroom, generally DF range of the sides near to window and aisle seats zone are not distributed well. Besides, two out of four school which are researched would not reach the standards of the law for school sanitary while rest of the schools meet the standards; Average DF 5% and Minimum DF 2%. And the result of a simulation by RADIANCE program shows the most appropriate DF range when it is applied in variable numbers about an oriehows the- South-east 15, south-east 30, south-east 45, south-west 15, south-west 30, and south-west 45 degrees. When it is applied in the variable numbers about glass transmittance - 60%, 70%, and 80% in condition facing south of a classroom, the result shows that the DF range of 80% transmittance is relatively higher than other glasses in the classroom. Thus, when a school is built, plans for an orientation is necessary for improve of elementary schools' environment with the glass installation which is made for high transmittance and is regarded with the students' activities time.

• Journal of Fisheries and Marine Sciences Education
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• v.27 no.1
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• pp.243-252
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• 2015

The present study, to examine the effect of the exercise for weight control, compares the difference of the heart rate and energy expenditure by sex during Twist exercise. Twenty eight adults (male 14, female 14) were carried out Twist exercise for 7 minutes and 14 minutes. During performing the exercise program, to perform HR and related variables were measured for 7 minutes and 14 minutes. Through a twist exercise treatment and the following results were obtained. 1. Females had slightly higher, without statistical significance, number of heart beat, minimum heart rate, maximum heart rate, and average heart rate than male had for both 7 minutes and 14 minutes of Twist exercise. 2. In the case of energy consumption, significant differences did not appear until 7 minutes to perform Twist exercise. On the other hand, the energy consumption for 14 minutes of performance was significantly higher in male than in female (p<.05). However, energy expenditure for the period per minute per unit weight (kcal/min/kg) showed no difference. 3. If more than 30 minutes duration were preformed the Twist exercise, males were expected to consume significantly higher than females (p<.05). To consume calories for the 10,000 step walk of, it would be required about 76 minutes for Twist exercise time without distinction of sex. Through the above findings, twist exercise is a form of aerobic exercise for obesity prevention and weight control, as well as it might be beneficial to practice and maintain the health and physical fitness with offering a variety of exercise opportunities in the public.

• Journal of Korean Medicine for Obesity Research
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• v.9 no.1
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• pp.1-14
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• 2009

Complex microbial communities play an important role in the human health and co-evolved with human in the form of symbiosis. Many literatures provide new evidences that the increased prevalence of obesity cannot be attributed solely to changes in the human genome, nutritional habits, or reduction of physical activity in our daily lives. The intestinal flora was recently proposed as an environmental factor responsible for the control of body weight and energy metabolism. A number of studies suggest that the modulation of gut microbiota affects host metabolism and has an impact on energy storage and demonstrated a role for the gut microbiota in weight gain, fat increase, and insulin resistance. Variations in microbiota composition are found in obese humans and mice and the microbiota from an obese mouse confers an obese phenotype when transferred to an axenic mouse. As well, the gut microbial flora plays a role in converting nutrients into calories. Specific strategies for modifying gut microbiota may be a useful means to treat or prevent obesity. Dietary modulations of gut microbiota with a view to increasing bifidobacteria have demonstrated to reduce endotoxemia and improve metabolic diseases such as obesity. The fermentation of medicinal herbs is intended to exert a favorable influence on digestability, bioavailability and pharmacological activity of herbal extract. Therefore we also expect that the fermented herbal extracts may open up a new area to treat obesity through modulating gut microbiota.

• Journal of Korean Medicine for Obesity Research
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• v.9 no.2
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• pp.21-32
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• 2009

Objectives Identification of individuals predisposed to obesity is an important issue for prevention and control of the obesity. It was reported that a high prevalence of obesity appeared in Taeumin among Sasang constitutions, but Enneagram personality-types has not been used to classify the patterns of obesity. These two classification methods were employed in combination in the current study, and it was analyzed whether the morbidity pattern of obesity can be characterized in further detail. Methods The subjects were 125 University students(62 males and 63 females) who answered both questionnaires for Sasang constitutions and Enneagram personality types. The obesity of students was classified by the obesity index and BMI. Results Only Taeumin group of Sasang constitutions was overweight, and the male of the group was overweight or obese. Analysis of the obesity index and BMI according to the Enneagram personality types showed significant differences(p<.05) between the types in the female group. These values were highest at the type 3 and lowest at the type 4. The physical indices according to both the centers of Enneagram and Sasang constitutions showed that only Taeumin female group had significant differences(p<.05) in the obesity index and BMI. Taeumin male group was overweight or obese in all centers of Enneagram and Taeumin female group was overweight or obese only in heart-center. Conclusions Diagnosis of the present data suggest that the classification of obesity patterns using Enneagram personality types in addition to Sasang constitutions is very useful to prevent and control the obesity.

• Nuclear Engineering and Technology
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• v.2 no.3
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• pp.149-161
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• 1970

This paper describes a detailed investigational performance on the gamma radiation shield effect of heavy concretes that were manufactured by the use of mineral ores produced domestically and which may be possibly applied for the biological shield design. Ten different kinds of mineral ores were collected for use as the aggregates, physical test and chemical analysis for them were carried out to select the aggregate with a better property. Through the experimental investigation on the shielding effect of various concretes with different combination of concrete components such as water-cement and fine-coarse aggregate ratios, it was possible to derive some criteria for the best condition being capable of obtaining the concretes with high density and good uniformity. Data on the shielding-effectiveness of the different concretes were obtained by performing collimated beam experiment using 60Co gamma-ray. Analyzing the shielding-efficiency, shielding-concrete specific gravity and biological shield cost, the optimum condition of yielding the best economic shielding design, with low cost and good spatial distribution to some extent was determined.

• Journal of Korean Society on Water Environment
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• v.23 no.5
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• pp.705-711
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• 2007

Green quantum-dot nanocrystal (QD525) with anti-microcystin monoclonal antibody was applied for detection of microcystin, a monocyclic peptide hepatotoxin, extracted from the culture of Microcystis aeruginosa. The presence of microcystin in the cell lysate was verified by HPLC analysis with UV absorbance at 238 nm. Microcystis cell extract exhibited fluorescence emission spectra, which peak was around 460 nm because of their complex organic substances. When a spherical QD525 antibody conjugates (10~20 nm in diameter) were bound to the microcystins in the Microcystis cell lysate, the fluorescence intensity of the primary peak at 525 nm diminished while the secondary emission peak at 460 nm slightly increased intensities. It is due to energy transfer from the primary (major) to the secondary (minor) peak, resulting from physical deformation of QD525 and different environmental factors. On the other hand, other cell extracts did not show any fluorescence emission change. This study is very available for detecting and monitoring the microcystin because it is one step assay without washing step and portable spectrophotometer makes on-site measurement possible. For health risk assessment of the microcystin, the reliable and rapid system to detect and quantify microcystin is seriously required.

• Proceedings of the Korea Water Resources Association Conference
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• 2005.09b
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• pp.1189-1192
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• 2005

Due to their slow degradation properties, hydrophobic organic contaminants in estuarine sediment have been a concern for risks to human health and aquatic organisms. Studies of fate and transport of these contaminants in estuaries are further complicated by the fact that hydrodynamics and sediment transport processes in these regions are complex, involving processes with various temporal and spatial scales. In order to simulate and quantify long-term attenuation of Polycyclic Aromatic Hydrocarbons (PAH) in the Elizabeth River, VA, we develop a modeling approach, which employs the U.S. Environmental Protection Agency's water quality model, WASP, and encompasses key physical and chemical processes that govern long-term fate and transport of PAHs in the river. In this box-model configuration, freshwater inflows mix with ocean saline water and tidally averaged dispersion coefficients are obtained by calibration using measured salinity data. Sediment core field data is used to estimate the net deposition/erosion rate, treating only either the gross resuspension or deposition rate as the calibration parameter. Once calibrated, the model simulates fate and transport PAHs following the loading input to the river in 1967, nearly 4 decades ago. Sediment PAH concentrations are simulated over 1967-2022 and model results for Year 2002 are compared with field data measured at various locations of the river during that year. Sediment concentrations for Year 2012 and 2022 are also projected for various remedial actions. Since all the model parameters are based on empirical field data, model predictions should reflect responses based on the assumptions that have been governing the fate and sediment transport for the past decades.