• Korean Journal of Plant Resources
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• v.25 no.5
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• pp.578-585
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• 2012

Cytokines released from innate immune cells play key roles in the regulation of the immune response. Red Ginseng (RG, steamed and dried root of Panax ginseng C.A. Meyer) is known to show different pharmacological effects by changed composition of saponins compared with Panax Ginseng. In this study, we examined the immunomodulatory effects of RG on the regulation of cytokine release in mice. RG was injected i.p at doses of 0.5, 5 and 50 mg/kg for 6 weeks. We assessed that the weight index of immune organs such as thymus, and spleen, and the mitogen blastogenesis of splenocytes. We also determined the levels of circulating cytokines in serum from RG-treated mice using ELISA assay. The weight index of thymus and spleen, and proliferation of mitogen response of splenocytes have increased in the RG-injected groups. In addition, the levels of IFN-${\gamma}$, TNF-${\alpha}$, IL-6, IL-12 and IL-2 concentrations have significantly increased in the serum of RG-treated mice, but that of IL-10 has not. These results suggest that RG has immune stimulating effects and could be useful as a immunoregulator of circulating cytokine release in vivo.

• Korean Journal of Plant Resources
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• v.24 no.4
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• pp.343-350
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• 2011

A medicinal herb, Stevia rebaudiana Bertoni which is grown under physical stresses such as simulated microgravity, shaking, and low temperature for 4 days, showed fresh weight decrease of 3.6%, 21% and 8.7% compared with the respective control. On control plants, the radical scavenging value of DPPH represented 86% and 55%, respectively in the leaves and stems extracts. Relatively weak antioxidant activities of 22% and 27% were measured respectively in AA (ascorbic acid) and BHA (beta-hydroxyacetic acid) known as synthetic antioxidants. The radical scavenging effect of DPPH (2,2-diphenyl-1-picryl hydazal) in stevia plants under a simulated microgravity was observed to be consistently higher relative to the control, whereas those effects of shaking and low temperature treatments rapidly increased and then reduced after 6 hours in case of shaking process and 24 hours in case of low temperature treatment, which results had similar levels of scavenging effects to the control. The plants under simulated microgravity showed the highest level of activity with the value of 147% and the shaking and low temperature treatments showed the increases of SOD activity by 121% and 125%, respectively. From the above results, it is clarified that the simulated microgravity is more effective to the antioxidant activity than those of other abiotic stresses.

• Food Science and Biotechnology
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• v.16 no.1
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• pp.29-36
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• 2007

Five phenolic compounds 1-5 were isolated for the first time from the exudate of geminating peanut (Arachis hypogaea). The structures were fully characterized by analysis of physical and spectral data. All isolated compounds were tested for antioxidant activities using 1,1-diphenyl-2-picrylhydrazyl (DPPH), 2,2-azino-bis-(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS), and hydroxyl radical. Compounds 2, 3, and 5 exhibited a strong scavenging effect on DPPH (2: $IC_{50}\;=\;10.4\;{\um}M$, 3: $IC_{50}\;=\;45.2\;{\mu}M$, 5: $IC_{50}\;=\;5.0\;{\mu}M$), and ABTS (2: $IC_{50}\;=\;9.6\;{\mu}M$, 3: $IC_{50}\;=\;5.5\;{\mu}M$, 5: $IC_{50}\;=\;3.3\;{\mu}M$) radical activity, whereas these compounds had weak hydroxyl radical scavenging activity ($IC_{50}\;>\;200\;{\mu}M$). The total phenolic contents of the extracts using n-hexane, EtOAc, and n-BuOH were found to be 96.4-964.3 mg gallic acid equivalent per g dry material (GAE/g) and n-BuOH fraction showed the highest total phenolic content (964.3 mg GAE/g). These studies suggest that the exudate of geminating peanut may possess possible health related benefits to humans.

• Korean Journal of Food Science and Technology
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• v.41 no.1
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• pp.16-20
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• 2009

To develop health functional foods using high amylose rice flours, the properties of flours prepared from domestic high amylose rice varieties, Goamy2 and Goamy, and imported rice from Thailand were investigated. After soaking the rice grains and drying, the dry-milled rice flours were passed through a 120-mesh sieve. The protein and total starch contents of the Goamy2 rice flour were lowest, but its crude lipid and ash contents were highest among the flours. In addition, apparent amylose content, water binding capacity, and total dietary fiber were highest in the Goamy2 flour (36.2, 255.0, and 9.2%, respectively). The Thai rice flour had the highest swelling power, whereas the Goamy2 flour had the lowest swelling power and solubility. By Rapid visco-analysis, the Thai flour showed the highest peak and total setback viscosities and lowest breakdown viscosity. The pasting pattern of the Goamy2 flour was different from that of the other flour, where low viscosity was maintained during heating and cooling. Goamy and Thai rice flours showed an A type crystallinity, but Goamy2 flour showed a B type crystallinity similar to high amylose maize starch. The Goamy2 flour presented a dull and yellowish color, and the lowest lightness (L) value and the highest yellowness (+b) value.

• Journal of Pharmacopuncture
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• v.19 no.3
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• pp.207-212
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• 2016

Objectives: Acupuncture treatments are safe and effective for a wide variety of diseases involving autonomic dysregulation. Heart rate variability (HRV) is a noninvasive method for assessing sympathovagal balance. The low frequency/high frequency (LF/HF) spectral power ratio is an index of sympathovagal influence on heart rate and of cardiovascular health. This study tests the hypothesis that from rest to 30% to 50% of peak oxygen consumption, the nonlinear Conte-Zbilut-Federici (CZF) method of computing the LF/HF ratio is a more reliable index of changes in the HRV than linear methods are. Methods: The subjects of this study were 10 healthy young adults. Electrocardiogram RR intervals were measured during 6-minute periods of rest and aerobic exercise on a cycle ergometer at 30% and 50% of peak oxygen consumption ($VO_{2peak}$). Results: The frequency domain CZF computations of the LF/HF ratio and the time domain computations of the standard deviation of normal-to-normal intervals (SDNN) decreased sequentially from rest to 30% $VO_{2peak}$ (P < 0.001) to 50% $VO_{2peak}$ (P < 0.05). The SDNN and the CZF computations of the LF/HF ratio were positively correlated (Pearson's r = 0.75, P < 0.001). fast Fourier transform (FFT), autoregressive (AR) and Lomb periodogram computations of the LF/HF ratio increased only from rest to 50% $VO_{2peak}$. Conclusion: Computations of the LF/HF ratio by using the nonlinear CZF method appear to be more sensitive to changes in physical activity than computations of the LF/HF ratio by using linear methods. Future studies should determine whether the CZF computation of the LF/HF ratio improves evaluations of pharmacopuncture and other treatment modalities.

• Journal of Korean Home Economics Education Association
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• v.21 no.4
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• pp.159-173
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• 2009

The purpose of this study was to develop a teaching learning process plan applying Keller's motive induction strategy to 'Nutrition and Meal' unit of the middle school home economics(HE). Five different problems were developed based on the 7th revised HE curriculum: "What should I do for a physical and mental health?", "What should I do to intake a required nutrient of my body?", "What should I do to take a well balanced diet?", "What should I do to build a desirable eating habits?" and "What should I do to deal with a nutrition issues?". This study was performed as the following procedures: the 'Nutrition and Meal' unit of the revised 7th middle school HE curriculum and the present HE textbooks were analyzed. And then the teaching learning process plan was designed, developed, evaluated, and revised. The motive induction strategies were developed based on the Keller's Motivational Tactics Checklist.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.12 no.2
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• pp.805-812
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• 2011

The elderly population has been dramatically increasing over the past years, but most of the population has developed chronic diseases and handicaps due to aging. High-intensity resistance training is one of the most effective ways to improve muscular strength, but it is unclear whether body composition and functional fitness would be increased by high-intensity resistance training. The aim of this investigation was to explore whether 12 weeks of high-intensity training would improve muscular strength, body composition, and functional fitness in women over the age of 70 years. Twenty-four participants were randomly assigned to a high-intensity resistance training group (n=8), a low-intensity resistance training group (n=8), and a control group (n=8). The experimental groups exercised 3 days per week for 12 weeks at a local fitness center. An analysis of variance(ANOVA) with repeated measures was used for analysis. The results showed that there was a significant improvement in agility and muscular strength following the high-intensity resistance training. Moreover, Moreover, %body fat and body fat mass decreased significantly after the 12 weeks of high-intensity resistance training(p<0.05). Based on these results, it was concluded that high-intensity resistance training is efficient for women over the age 70 years in increasing their muscular strength and functional fitness and reducing their total body fat mass.

• Korean Journal of Community Nutrition
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• v.13 no.4
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• pp.489-498
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• 2008

This study was carried out to identify bone mineral density(BMD), body composition, lifestyle and dietary habits of young women by physical measurement and questionnaires. The study subjects, 190 young women living in Seoul, were divided into three age groups: $20{\sim}24$ years(93), $25{\sim}29$ years(44) and $30{\sim}39$ years(53). There was no significant difference in mean body muscle mass, protein, mineral, body fat and BMI among the three age groups. The rate of low weight(18%) in 20 years group was higher that of the 30 years(11.3%). The mean BMD and T-score were $0.44g/cm^2$ and -0.66. BMD and T-score of the forearm bone were significantly higher in the $30{\sim}39$ years group. But BMD and T-score of calcanues were not significantly different among the three age groups. The rate of normal, osteopenia and osteoporosis subjects by BMD were 60.5%, 38.4%, 1.1%, respectively. The rate of osteopenia in $20{\sim}24$ years group was significantly higher than the other age groups. The rate of meal irregularity was significantly higher in $20{\sim}24$ years group. The rate of women who walk and are exposed to sunlight more than 1hr per day were significantly higher in $20{\sim}24$ years group than the others. However, the score of food behaviors is significantly higher(bad) in $20{\sim}24$ years group than the others. The relationship between BMD and frequency of food intake showed significant differences in beans, broom, seaweed and rice wine. In conclusion, the risk rate of BMD was very high, 40% of the subjects, and the risk rate of BMD was higher in 20 years group than 30 years group, and the rate of low weight in 20 years group was higher than in 30 years group. The food habits and behaviors were not healthy enough. Therefore, nutrition education is needed for bone health.

• Restorative Dentistry and Endodontics
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• v.35 no.5
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• pp.344-352
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• 2010

Objectives: The purpose of this study was to determine the setting time, compressive strength, solubility, and pH of mineral trioxide aggregate (MTA) mixed with glass ionomer cement (GIC) and to compare these properties with those of MTA, GIC, IRM, and SuperEBA. Materials and Methods: Setting time, compressive strength, and solubility were determined according to the ISO 9917 or 6876 method. The pH of the test materials was determined using a pH meter with specified electrode for solid specimen. Results: The setting time of MTA mixed with GIC was significantly shorter than that of MTA. Compressive strength of MTA mixed with GIC was significantly lower than that of other materials at all time points for 7 days. Solubility of 1 : 1 and 2 : 1 specimen from MTA mixed with GIC was significantly higher than that of other materials. Solubility of 1 : 2 specimen was similar to that of MTA. The pH of MTA mixed with GIC was 2-4 immediately after mixing and increased to 5-7 after 1 day. Conclusions: The setting time of MTA mixed with GIC was improved compared with MTA. However, other properties such as compressive strength and pH proved to be inferior to those of MTA. To be clinically feasible, further investigation is necessary to find the proper mixing ratio in order to improve the drawbacks of MTA without impairing the pre-existing advantages and to assess the biocompatibility.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.2
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• pp.962-969
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• 2014

This study investigated the patterns and correlations of spinopelvic alignments in in middle school and high schools students of Gyeongnam areas in Korea using rasterstereography. Sixty-one subjects were recruited from May to October 2013, the average age of subjects was $16.40{\pm}2.20$ years. In the present results, PSIS ratio was statistically different between the sexes(male $21.15{\pm}2.40$%, female $23.41{\pm}3.28$%)(p<.01) and lordotic angle was statistically different between the sexes(male $33.44{\pm}8.46^{\circ}$, female $38.96{\pm}8.11^{\circ}$)(p<.001), but other parameters were not statistically different between the sexes. However, we verified that lordotic angle was significant correlation separately with pelvic tilt(r=.348), kyphotic angle(r=.609). Surface rotation was significant correlation separately with kyphotic angle(r=-.278), lordotic angle(r=-.256), trunk inclination(r=.493). These finding could be used as basic data research to confirm normal pattern of spinopelvic alignment and balance in health adolescents, and might help understand adolescents with structure problem in spine and pelvis.