• Title/Summary/Keyword: (D/C) ratio

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Studies on the Purification and Characterization of H-Y Antigen (H-Y 항원의 정제 및 특성규명에 관한 연구)

  • Chung, M.K.;Paik, J.M.;Lee, J.L.;Heo, Y.S.;Kim, C.K.;Kim, J.B.
    • Clinical and Experimental Reproductive Medicine
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    • v.21 no.1
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    • pp.89-97
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    • 1994
  • These studies were carried out to investigate the properties of H-Y antigen purified by immunoaffinity chromatography using monoclonal H-Y antibody. Immunoaffinity column was prepared by the coupling of monoclonal antibody to the Aminolink Coupling Gel. Murine testis supernatant was applied onto the column and eluted by O.lM glycine-HCl buffer and 31${\mu}g$ of H-Y Ag was eluted from one testis. Purified H-Y Ag strongly reacted with Con A and lentil from 6 different kinds of lectins tested, which may indicate that sugar moiety of H-Y Ag is composed of glucose, mannose and their derivatives. Con A-sepharose affinity column was used to purified H-Y Ag based on that H-Y Ag is glycoprotein. The fraction eluted by 0.2M Me-${\alpha}$-D-mannoside from the column loaded with murine testis supernatant was identified to be H-Y Ag by dot blot test. Molecular weight of the purified H-Y Ag was estimated by Sepharose G-75 gel filtration and SDS-PAGE, and showing that it was about 67,000 dalton. In fluorescence test, the ratio of XY embryos and XX embryos was 1:1.

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Influence of Controlling Protozoa on the Degradation and Utilization of Dietary Fibre and Protein in the Rumen and Nitrogenous Flow Entering the Duodenum of Sheep

  • Han, C.Y.;Lu, D.X.;Hu, M.;Tan, Z.L.
    • Asian-Australasian Journal of Animal Sciences
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    • v.12 no.8
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    • pp.1241-1245
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    • 1999
  • Nine two-year old sheep fitted with rumen and duodenum cannulas were used to study the effect of controlling protozoa flora on the degradation and utilization of dietary fibre and protein in the rumen and on nitrogenous flow to the duodenum. There were three groups in this experiment: defaunation (DF); partial defaunation (PDF); faunation (F) as control. Results showed that: 1,There were no differences between treatments in dietary DM degradation in the rumen, but defaunation and partial defaunation increased the quantity of nitrogenous material in the rumen and the flow of N to duodenum. 2, partial defaunation and defaunation improved the degradabilities of dietary NDF, ADF and HC, but there were no differences between the defaunated and partially defaunated groups. 3, Partial defaunation decreased the degradability of dietary protein in the rumen. There was no difference between defaunated and faunated groups. 4, Defaunation and partial defaunation increased the quantity of total N (TN) and microbial N (MCN) in the rumen and the amounts entering the duodenum. The protozoa N (PN) flow in the faunated group was higher than that in the partially defaunated group, and the amino acid pattern in the digesta at the proximal duodenum in the defaunated group was closer to the ideal amino acid pattern. 5, There were differences in the mole percent of acetic, propionic, total-VFAs and the non-glucogenic to glucogenic VFAs ratio (NGR) value in the rumen fluids. The order was as follows: mole percent of acetate: F>PDF>DF; mole percent of propionate: DF>PDF>F; total-VFAs: PDF>F>DF; NGR: F>PDF>DF.

Synthesis of Gallosilicate(Ga-MFI} and Its Comparison with ZSM-5 (갈리실리케이트(Ga-MFI)의 합성 및 ZSM-5와의 비교)

  • Kim, Young-Kook;Hwang, Jae-Young;Kim, Myung-Soo;Park, Hong-Soo;Hahm, Hyun-Sik
    • Journal of the Korean Applied Science and Technology
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    • v.21 no.3
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    • pp.231-237
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    • 2004
  • Ga-MFI was synthesized by a hydrothermal process at atmospheric pressure. The effect of mole ratios of reactants on crystallization was also investigated thoroughly. The characteristics of synthesized Ga-MFI was compared with ZSM-5. The synthesis of Ga-MFI was carried out with five different mole-compositions of $\underline{a}SiO_2-\underline{b}Ga_2O_3-\underline{c}Na_2O-\underline{d}TPA_2o-\underline{e}H_2O$. The synthesized Ga-MFI and ZSM-5 were characterized by XRD and FT-IR. The inorganic cation ($Na^+$) and water played an important role in crystallinity and the organic cation ($TPA^+$) as a template played a great influence on yields. With the increase in the amount of $Ga^{3+}$, crystallization time was increased. With a fixed $SiO_2/Ga_2O_3$ ratio of 400, the optimum reaction condition was obtained at $H_2O/SiO_2$=30${\sim}$35, $Na_2O/SiO_2$=0.5${\sim}$0.6, and $TPA_2O/Na_2O$=1${\sim}$1.25. In these cases, the crystallinity and yield were more than 95% and 90%, respectively. By comparing IR spectrum of Ga-MFI with those of ZSM-5 and silicalite, it was found that Ga-MFI showed a unique peak at 970 $cm^{-1}$, which may be used to identify Ga-MFI from ZSM-5 and silicalite.

Pharmacokinetic Comparison of Lamisil Tablet and Muzonal Tablet Containing Terbinafine HCl in Healthy Volunteers (건강한 지원자에 있어서 염산테르비나핀 함유 라미실정과 무조날정의 약물동력학적 비교)

  • Choi Han-Gon;Yong Chul Soon;Rhee Jong-Dhal;Woo Jong-Soo;Lee Kyung Hee;Yoo Bong Kyu
    • YAKHAK HOEJI
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    • v.49 no.4
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    • pp.255-259
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    • 2005
  • Financial standing of National Health Insurance has been experiencing a grave deterioration during the last 4-5 years, and the yearly amount paid by the insurance for drug expense rose up to 4 trillion won recently. Furthermore, the ratio of drug expenses in the total expenditure of the insurance reached about $25\%$, showing the tendency to be levelled off. As a measure to improve the financial deterioration of the insurance and to encourage generic substitution among the health professionals, we compared pharmacokinetic parameters of brand name drug (Lamisil) and generic drug (Muzonal) containing terbinafine HCl in healthy volunteers. The area under the curve (AUC) of the two drugs showed $2220.4\pm784.7\;and\;2143.1\pm861.6hr{\cdot}ng/ml$ in the corresponding order and no statistically significant difference was identified. The peak concentration $(C_{max})$ of the generic drug demonstrated $566.6\pm246.2 ng/ml$ compared to $550.8\pm204.0$ of brand name drug, which was not significantly different either. Time to reach peak concentration showed about 6 minutes difference between the drugs, which has no clinical significance to the treatment of dermatomycosis and dermatophytosis.

Clinical Evaluation of Empyema Treated by Open Thoracotomy Drainage (Open thoracotomy drainage 를 받은 농흉환자의 임상적 고찰)

  • Han, Yeong-Suk;Kim, Se-Hwa;Lee, Hong-Gyun
    • Journal of Chest Surgery
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    • v.11 no.1
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    • pp.35-41
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    • 1978
  • After the advent of the effective antimicrobial drugs, empyema of the pleural cavity came to be considered an infrequent disease. However, in recent years the problem of empyema is increasing, probably due to bacterial changes associated with the use and misuse of antimicrobials as well as alterations in the host associated with increased longevity and chronic disease. During the 10 years period from 1957, Sop. to 1977, Aug., we experienced 152 cases of empyema, of which 37 were scheduled on open thoracotomy drainge for chronic empyema. 1. The ratio of male to female was 3.6:1 with male predominance and 64% of total was above 40 years old in age distribution. 2. The cardinal symptoms were fever[70%], dyspnea[40.5%], and sputum[40.5%]. The leucocytosis were observed in 75.7% of all cases. The hemoglobin level showed subnormal in 21.6% of all cases. 3- The underlying pathology predisposing to empyema were postoperative empyema [35.1%] and tuberculosis[32.4%] in order. 4. The pathologic organisms by bacterial culture in 37 patients were Pseudomonas [24.3%], Staphylococccus [21.6%], Streptococcus [21.6%]., no growth [8. 1%] and the remainders. 5. The late results were as follow; a. Spontaneous closure was seen in 10 patients and all of them belongs to non-tuberculous group. Their mean duration was 14 months. b. Still opened are eight; 6 in tuberculous group, remainders in non-tuberculous group. c. Secondary closure was performed in 6 patients, of which 5 cases showed successful secondary closure but one failed. The mean duration from OTD to secondary closure was 46.3 days. d. Eleven patients were not followed. e. Two patients were expired; one was due to progressive cachexia and pulmonary insufficiency, the other due to gastrointestinal bleeding unrelated to empyema.

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Three Phase Embedded Z-Source Inverter (3상 임베디드 Z-소스 인버터)

  • Oh, Seung-Yeol;Kim, Se-Jin;Jung, Young-Gook;Lim, Young-Cheol
    • The Transactions of the Korean Institute of Power Electronics
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    • v.17 no.6
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    • pp.486-494
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    • 2012
  • In this paper, we proposes the three-phase embedded Z-source inverter consisting of the three embedded Z-source converters and it's the output voltage control method. Each embedded Z-source converter can produce the bipolar output capacitor voltages according to duty ratio D such as single-phase PWM inverter. The output AC voltage of the proposed system is obtained as the difference in the output capacitor voltages of each converter, and the L-C output filter is not required. Because the output AC voltage can be stepped up and down, the boost DC converter in the conventional two-stage inverter is unnecessary. To confirm the validity of the proposed system, PSIM simulation and a DSP based experiment were performed under the condition of the input DC voltage 38V, load $100{\Omega}$, and switching frequency 30kHz. Each converter is connected by Y-connection for three-phase loads. In case that the output phase voltage is the same $38V_{peak}$ as the input DC voltage and is the 1.5 times($57V_{peak}$), the simulation and experimental results ; capacitor voltages, output phase voltages, output line voltages, inductor currents, and switch voltages were verified and discussed.

Model Tests on the Bearing Capacity and Settlement of Footing Considering Scale Effect (Scale Effect를 고려한 기초의 지지력 및 침하량 산정을 위한 모형실험)

  • 정형식;김도열;김정호
    • Journal of the Korean Geotechnical Society
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    • v.19 no.5
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    • pp.343-354
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    • 2003
  • The scale effect should be considered to determine the bearing capacity and settlement of footings from Plate-Load Test, because of the size difference between a footing and a loading plate. To analyze characteristics of bearing capacity and settlement according to the difference of loading plate sizes, model tests were performed with four different sizes of square plate, which are B=10, 15, 20 and 25cm, on five different kinds of subsoil. Based on the analyzed results, this paper also proposes a method of bearing capacity and settlement determination, where scale effect is considered depending on the mixing ratio of sand and clay. Until now, uneconomic constructions have been conducted because of unreasonable evaluation in estimating bearing capacity and settlement of footings from Plate-Load Test in fields. In the application of the formula proposed in this research to field problems, it is expected that evaluation of bearing capacity and settlement of footings can be more reliable and more economic construction can be achieved.

Influence of gas mixture He-Ne-Xe on the vacuum ultraviolet intensity in ac-PDPs.

  • Yoo, N.L.;Jung, K.B.;Lee, J.H.;Lee, S.B.;Han, Y.K.;Jeong, S.H.;Lee, H.J.;Son, C.G.;Lim, J.E.;Oh, P.Y.;Moon, M.W.;Jeoung, J.M.;Ko, B.D.;Cho, G.S.;Uhm, H.S.;Choi, E.H.
    • 한국정보디스플레이학회:학술대회논문집
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    • 2005.07b
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    • pp.1221-1224
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    • 2005
  • The improvement of luminance and luminous efficiency is the one of the most important parts in AC-PDPs. To achieve high luminance and luminous efficiency, high VUV emission efficiency is needed. We measured the emission spectra of the vacuum ultraviolet(VUV) rays in surface discharge AC-PDP with ternary gas mixture of He-Ne-Xe. The influence of He-Ne-Xe gas-mixture ratio on excited $Xe^{\ast}$ resonant atoms and $Xe_2\;^{\ast}$ dimers has been investigated. It is found that luminous efficiency of ternary gas mixture, He-Ne-Xe, is shown to be much higher than that of binary gas mixture of Ne-Xe. For improving discharge luminous efficiency, we have studied VUV emission characteristics of ternary gas mixture, He(50%)-Ne-Xe and He(70%)-Ne-Xe with Xe concentration and filling gas pressure.

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Development of Eddy Current Test Probe for Profilometry Inspection of Tube (원형튜브 단면형상검사용 와전류탐촉자 개발)

  • Lee, H.J.;Nam, M.W.;Lee, C.H.
    • Journal of the Korean Society for Nondestructive Testing
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    • v.17 no.4
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    • pp.262-269
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    • 1997
  • An eddy current probe ($8{\times}1$ multiple-element, surface scan) was successfully designed and fabricated at the KEPRI using the impedance equivalent circuit theory. The probe is intended for the detection of circumferential deformations (cross-section view) of the heat exchanger tubing that can occur due to corrosion, erosion, and denting. Optimum design parameters providing the highest sensitivity and signal-to-noise ratio, such as the coil dimensions, electrical characteristics, and test frequencies, were determined based on initial laboratory experiments conducted on the test specimen (SS304 tubing: OD : 9.68mm, wall-thickness : 0.47mm) containing artificial flaws (e.g., dents and corroded surface on tube OD) using the available Zetec-made probe. Using this parameters, a new probe was made and tested on an unknown specimen. The result indicated that the new probe is capable of detecting the circumferential deformation with the error of ${\pm}0.2%$ (0.022mm) of the tube O.D.

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Etiologic Classification of Recurrent Spontaneous Abortion (습관성 유산의 원인적 분류)

  • Park, Moon-Il;Lee, Ki-Hun;Chung, Sung-Ro;Lee, Jai-Auk;Moon, Hyung;Kim, Doo-Sang
    • Clinical and Experimental Reproductive Medicine
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    • v.18 no.1
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    • pp.113-120
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    • 1991
  • Etiologic classification was performed in 155 patients with recurrent spontaneous abortion history. The incidence was 9.3% among 1658 pregnant women at Hanyang university hospital during the same period. In etiologic classification, 37 cases of on-going patients for diagnostic evaluation were excluded. Of the remained 118 patients, the patients with unknown etiology were 32 cases (27.1%), and 86 cases were classified into each etiologies using appropriate diagnostic modalities. Anatomic causes were the largest etiology, which revealed 46.6% (55 among 118 patients). The next etiology was immunologic cause, which revealed 24.6% (29 patients). Of the 86 patients who have at least one cause, 40.7% (35 among 86) have two or more etiologies. Furthermore, six cases (7%) have 3 combined etiologies. The uterine synechia and/or incompetent internal os of the cervix, namaly anatomic causes, revealed highest combination ratio than other etilogies. The popular abortion technique in Korea, D&C, seems to be main factors for these anatmic causes. The combined causes rather than single cause of recurrent spontaneous abortion were unique situation in Korea especially with anatomic etiologies. From this point of view, we think anatomic etiologies should be rule out first in the evaluation of the patients. For this purpose, we believe hysteroscopy would be helpful as a diagnostic work-up and treatment modality in the management of recurrent spontaneous abortion patients in Korea.

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