• The Journal of Korean Institute of Communications and Information Sciences
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• v.38C no.2
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• pp.189-195
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• 2013

In this paper, a land and maritime unified tourism information guide system is proposed which employs robust speech recognition in ship noise environments. Most of conventional front-ends for speech recognition have used a Wiener filter to compensate for stationary noise such as car or babble noises. However, such the conventional front-ends have limitation in reducing non-stationary noise that are occurred inside the ship on voyage. To overcome such a limitation, the proposed system incorporates nonlinear multi-band spectral subtraction to provide highly accurate tourism route recognition. It is shown from the experiment that compared to a conventional system the proposed system achieves relative improvement of a tourism route recognition rate by 5.54% under a noise condition of 10 dB signal-to-noise ratio (SNR).

• KSCE Journal of Civil and Environmental Engineering Research
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• v.37 no.1
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• pp.119-124
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• 2017

In this paper, 18 railway stations in Gyunggi-do are selected as metropolitan transfer centers out of 203 stations based on three elements. They are the number of passengers, the level of connection transport, and the level of relevant plans. For 18 stations the level of service (LOS) is analyzed for connection transport system. As a result, half of them are found to be below LOS "D". In order to maximize the use of those railway stations, a method is proposed to upgrade the level of service to "C" above. Finally, the improvement plans are suggested for two acts. In the Special Act on Metropolitan Traffic Management of the Metropolitan Region, the central government financial support ratio is suggested from 30% to 50%, from "necessary costs" to "total costs." In the Act on National Integrated Transport System Efficiency, 50% for connection road and 70% for connection raiway are suggested.

• Agribusiness and Information Management
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• v.6 no.1
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• pp.1-11
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• 2014

The purpose of this study is to develop the growth prediction model that can predict growth and development information influencing on the production of citrus fruits. The growth model was developed to predict the floral leaf ratio, number of fruit sets, fruit width, and overweight fruits depending on the main period of growth and development by considering the weather factors because the fruit production is influenced by weather depending on the growth and development period. To predict the outdoor-grown citrus fruit production, the investigation result for the standard farms is used as the basic data; in this study, we also understood that the influence of weather factors on the citrus fruit production based on the data from 2004 to 2013 of the outdoor-grown citrus fruit observation report in which the standard farms were targeted by the Agricultural Research Service and suggested the growth and development information prediction model with the weather information as an independent variable to build the observation model. The growth and development model for outdoor-grown citrus fruits was assumed by using the Ordinary Least Square method (OLS), and the developed growth prediction model can make a prediction in advance with the weather factors prior to the observation investigation for the citrus fruit production. To predict the growth and development information of the production of citrus fruits having a great ripple effect as a representative crop in Jeju agriculture, the prediction result regarding the production applying the weather factors depending on growth and development period could be applied usefully.

• Korean Journal of Veterinary Service
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• v.16 no.2
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• pp.127-137
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• 1993

Carbon tetrachloride ($CCl_4$) has been used to treat a variety of parasitic infection in both large and small animals, including Fasciola hepatica. Recently, we can easily contest with carbon tetrachloride in air, food, water, rain and Industry area etc. and it is using in order to induce liver injury in laboratory. In this study. we investigated activitis of LDH, ALP, AST and ALT and amount of cholesterol, triacylglycerol, glucose and BUN in mice serum exposed to $CCl_4.$ The mice divided Into a Naive control(A), corn oil control(B) and experimental group(C, D). Naive control group(A) was given feed and water only. Corn oil control group(B) was given corn oil 1ml /100g of body weight(B.W). Experimental group(C) was given carbon tetrachloride 1ml /100g B.W. ($CCl_4$： corn oil=1：20(V /V) ), Experimental group(D) was given carbon teterachloride 1ml /100g B.W. ($CCl_4$: corn oil=1：10(V /V) ). The results obtained were summarized as follows : 1) The body weight was declined after the l0th day In mice exposed to carbon tetra-chloride. 2) The total protein level in serum was significantly in mice exposed to carbon tetra-chloride($P{\leq}0.05$). The albumin and A /G ratio was decresed significantly in mice exposed to carbon tetrachloride($P{\leq}0.01$) 3) All of the activity of LDH, AST, ALT and ALP in mice serum exposed to carbon tetra chloride inclosed significantly activity of LDH ($P{\leq}0.05$), inclosed significantly activity of AST($P{\leq}0.05, \;p {\leq}0.01$), inclosed significantly activityof ALT 3nd ALP($P {\leq}0.05,\;p {\leq}0.01$). 4) The amount of cholesterol and triacylglycerol, lipid metabolite products in serum was inclosed in case of cholesterol but did not change in case of triacylglycerol.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.29 no.12
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• pp.915-923
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• 2018

A concrete embedded antenna design is proposed for probing the durability of a building at an industrial scientific medical band of 902~908 MHz. The proposed antenna is designed with a stacked slot patch structure for lower impedance variation to a dielectric constant of concrete, as a dielectric constant difference is derived from the moisture content. The proposed structure has a wider bandwidth when a parasitic patch structure is used, which reduces antenna performance degradation resulting from the moisture content of concrete. The measured voltage standing wave ratio of the proposed structure is less than 2 and the beam width is approximately $80^{\circ}$, whereas the gain is greater than 7 dBi. The proposed antenna is fabricated with a rectangle-type concrete block, which is simulated and measured for return loss and antenna gain.

• Journal of the Architectural Institute of Korea Structure & Construction
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• v.35 no.9
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• pp.143-150
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• 2019

The purpose of this study was to propose how to determine the setting time related to the determination of the surface finish working time of the concrete using a Durometer, which is used as a rubber hardness meter. Two different types of Durometer were used to measure the setting time of the concrete. High flowing concrete with 40% of water to binder ratio was fabricated maintaining $600{\pm}100mm$ of slump flow. The test results indicated that the application of the Durometer resulted in a high correlation with the penetration resistance tester in both mortar and concrete. When measuring the setting time of the concrete, with properly used with Durometer, evaluation of the setting time of the concrete can be available. Therefore, it is thought that the measurement of the final set of the durometer C type can be useful to decide the limit time of the finishing operation and the time of the rejuvenation of the curing process by measuring the finishing set at 40 HD in the case of the initial set and 10 HD in the case of D type.

• Childhood Kidney Diseases
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• v.26 no.1
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• pp.52-57
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• 2022

Purpose: To determine predictive factors for detecting renal parenchymal damages (RPDs) in infants with recurrent febrile urinary tract infection (fUTI). Methods: From January 2015 to December 2021, 102 infants with recurrent fUTI and who underwent ^99mTc-dimercaptosuccinic acid (DMSA) renal scan in our hospital were included in this study. Controls included infants with normal DMSA results performed 3 months apart from the 2nd episode of fUTI. DMSA-positive group included infants with positive DMSA results performed 3 months apart from the 2nd episode of fUTI or at the 3rd episode of fUTI. The recurrence rate, causative bacteria, renal size discrepancy of both kidneys, and laboratory findings including C-reactive protein (CRP) and spot urine sodium-to-potassium ratio (uNa/K) were compared between both groups. Results: Only 3.8% of 79 infants with a 2nd episode of fUTI showed positive DMSA results. fUTI recurred more frequently within 12 months of follow-up in the DMSA-positive group than in the control group (69% vs. 13%, P<0.001). CRP values were significantly higher in the DMSA-positive group than in the control group (7.3 mg/dL vs. 3.7 mg/dL, P<0.001). Spot uNa/K were significantly lower in the DMSA-positive group than in the control group (0.6 vs. 1.1, P<0.001). Conclusions: Congenital renal scar and RPDs on the DMSA scan were more frequently found in infants with recurrent fUTI than those in the control group. High CRP values and low spot uNa/K in acute infections were helpful in predicting the presence of RPD in infants with recurrent fUTI.

• Journal of Gastric Cancer
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• v.23 no.2
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• pp.289-302
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• 2023

Purpose: Liver metastasis (LM) is reported in approximately 40% of patients with advanced/metastatic gastric/gastroesophageal junction adenocarcinoma (metastatic esophagogastric adenocarcinoma; mGEA) and is associated with a worse prognosis. This post-hoc analysis from the RAINBOW trial reported the efficacy, safety, and biomarker outcomes of ramucirumab and paclitaxel combination treatment (RAM+PAC) in patients with (LM+) and without (LM-) LM at baseline. Materials and Methods: Patients (n=665) were randomly assigned on a 1:1 basis to receive either RAM+PAC (LM+: 150, LM-: 180) or placebo and paclitaxel (PL+PAC) (LM+: 138, LM-: 197). The overall survival (OS) and progression-free survival (PFS) were evaluated using stratified Kaplan-Meier and Cox regression models. The correlation of dichotomized biomarkers (VEGF-C, D; VEGFR-1,2) with efficacy in the LM+ versus LM- subgroups was analyzed using the Cox regression model with reported interaction P-values. Results: The presence of LM was associated with earlier progression than those without LM, particularly in patients receiving PL+PAC (hazard ratio [HR], 1.68). RAM+PAC treatment improved OS and PFS irrespective of LM status but showed greater improvement in LM+ than that in LM- (OS HR, 0.71 [LM+] vs. 0.88 [LM-]; PFS HR, 0.47 [LM+] vs. 0.76 [LM-]). Treatment-emergent adverse events were similar between patients with and without LM. No predictive relationship was observed between biomarker levels (VEGF-C, D; VEGFR-1,2) and efficacy outcome (OS, PFS) (all interaction P-values >0.05). Conclusions: RAM provided a significant benefit, irrespective of LM status; however, its effect was numerically stronger in patients with LM. Therefore, RAM+PAC is a clinically meaningful therapeutic option for patients with mGEA and LM.

• Advances in environmental research
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• v.12 no.1
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• pp.51-64
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• 2023

The sustainable management of rice straw is essential for protection of human health and environment. This study assesses the impact of stock density of earthworm (Eisenia fetida) and Neem leaves (Azadirachta indica) on the quality of the final vermicompost. The vermicompost is produced using different combinations of rice straw, Neem leaves, and cow dung (bulking agent) by varying stock density of earthworms. The vermicomposting experiments are performed in plastic containers (32 cm × 28 cm × 28 cm) in open for 90 days under laboratory conditions. The stock density of the earthworm is found to be an important factor to influence nutritional quality of the final vermicompost. There is observed significant improvement in the total nitrogen (91.8%), phosphate (73.4%), potassium (38.8%), and calcium (59.05%) content of the vermicompost produced with the highest stock density of the earthworms. All the treatments showed decrease in TOC and C:N content after 90 days of vermicomposting. The treatment with Neem leaves showed maximum growth of earthworms (2.65 fold). Neem leaves brought positive changes in the quality of final vermicompost by enhancing the growth and reproduction of the earthworms. The calcium content increased by 39% in the final vermicompost with the addition of Neem leaves at the same stock density of the earthworms. The stock density of the earthworms and Neem leaves are found to significantly improve quality of the final vermicompost as compared with the compost (control). The surface morphology in SEM images showed high degree of fragmentation in the vermicompost as compared with the compost. The combined action of microbes and earthworms resulted in high degree of disintegration in the vermicompost.

• Biomolecules & Therapeutics
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• v.31 no.4
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• pp.411-416
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• 2023

Methamphetamine (METH) is a powerful neurotoxic psychostimulant affecting dopamine transporter (DAT) activity and leading to continuous excess extracellular dopamine levels. Despite recent advances in the knowledge on neurobiological mechanisms underlying METH abuse, there are few effective pharmacotherapies to prevent METH abuse leading to brain damage and neuropsychiatric deficits. α-Pinene (APN) is one of the major monoterpenes derived from pine essential oils and has diverse biological properties including anti-nociceptive, anti-anxiolytic, antioxidant, and anti-inflammatory actions. In the present study, we investigated the therapeutic potential of APN in a METH abuse mice model. METH (1 mg/kg/day, i.p.) was injected into C57BL/6 mice for four alternative days, and a conditioned place preference (CPP) test was performed. The METH-administered group exhibited increased sensitivity to place preference and significantly decreased levels of dopamine-related markers such as dopamine 2 receptor (D2R) and tyrosine hydroxylase in the striatum of the mice. Moreover, METH caused apoptotic cell death by induction of inflammation and oxidative stress. Conversely, APN treatment (3 and 10 mg/kg, i.p.) significantly reduced METH-mediated place preference and restored the levels of D2R and tyrosine hydroxylase in the striatum. APN increased the anti-apoptotic Bcl-2 to pro-apoptotic Bax ratio and decreased the expression of inflammatory protein Iba-1. METH-induced lipid peroxidation was effectively mitigated by APN by up-regulation of antioxidant enzymes such as manganese-superoxide dismutase and glutamylcysteine synthase via activation of nuclear factor-erythroid 2-related factor 2. These results suggest that APN may have protective potential and be considered as a promising therapeutic agent for METH-induced drug addiction and neuronal damage.